CAS 926279-93-8

H-GGEEEEYFELVKKKK-OH

CAS: 926279-93-8

JAK3tide is a synthetic peptide, which is a highly specific substrate. Derived from comprehensive biochemical studies, it targets the catalytic activity of the Janus kinase 3 (JAK3) enzyme. JAK3tide's mode of action involves being phosphorylated by JAK3, an essential kinase involved in the signaling pathways of certain cytokines, making it a vital tool for assaying JAK3 activity.When used in in vitro kinase assays, it enables precise quantification of JAK3's enzymatic activity, which is pivotal for understanding pathway dynamics involved in immune responses. Its application extends to research areas focused on elucidating the mechanisms of immune signaling pathways and for the development of inhibitors as potential therapeutic agents in immunological disorders. JAK3tide provides a robust framework for scientists aiming to dissect the nuanced interactions within the JAK-STAT pathway and identify novel therapeutic targets, particularly in conditions where JAK3 is dysregulated.

Formula: C₈₂H₁₂₉N₁₉O₂₇

Peso molecolare: 1,813.02 g/mol

Ref: 3D-PP50894