CAS 92823-03-5

Flomoxef sodico

Descrizione:

Flomoxef sodico è un antibiotico cefalosporinico ad ampio spettro, utilizzato principalmente per le sue proprietà antibatteriche. È efficace contro una varietà di batteri Gram-positivi e Gram-negativi, rendendolo utile nel trattamento di infezioni causate da questi patogeni. Il composto è caratterizzato dalla sua capacità di resistere all'idrolisi da parte di alcune beta-lattamasi, il che ne migliora l'efficacia contro ceppi batterici resistenti. Flomoxef sodico viene tipicamente somministrato per iniezione ed è noto per il suo profilo di tossicità relativamente basso. La sua farmacocinetica include una buona penetrazione nei tessuti e una emivita favorevole, consentendo regimi di dosaggio efficaci. La sostanza è spesso utilizzata in contesti clinici per trattare infezioni delle vie respiratorie, infezioni del tratto urinario e infezioni cutanee. Come per qualsiasi antibiotico, il potenziale sviluppo di resistenza richiede una considerazione attenta del suo utilizzo, ed è importante seguire le linee guida per una prescrizione appropriata per mitigare questo rischio. Nel complesso, Flomoxef sodico rappresenta un'opzione preziosa nell'arsenale delle terapie antimicrobiche.

Formula: C₁₅H₁₈F₂N₆O₇S₂·Na

InChI: InChI=1S/C15H18F2N6O7S2.Na/c1-29-15(18-8(25)6-31-13(16)17)11(28)23-9(10(26)27)7(4-30-12(15)23)5-32-14-19-20-21-22(14)2-3-24;/h12-13,24H,2-6H2,1H3,(H,18,25)(H,26,27);/t12-,15+;/m1./s1

InChI key: InChIKey=SYHZUFMYQQRMKT-YLCXCWDSSA-N

SMILES: N(C(CSC(F)F)=O)[C@@]1(OC)[C@@]2(N(C1=O)C(C(O)=O)=C(CSC=3N(CCO)N=NN3)CO2)[H].[Na]

Sinonimi:

• 5-Oxa-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-((((difluoromethyl)thio)acetyl)amino)-3-(((1-(2-hydroxyethyl)-1H-tetrazol-5-yl)thio)methyl)-7-methoxy-8-oxo-, monosodium salt, cis-
• 5-Oxa-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(2-((difluoromethyl)thio)acetamido)-3-(((1-(2-hydroxyethyl)-1H-tetrazol-5-yl)thio)methyl)-7-methoxy-8-oxo-, sodium salt,(6R,7R)-
• 5-Oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[[(difluoromethyl)thio]acetyl]amino]-3-[[[1-(2-hydroxyethyl)-1H-tetrazol-5-yl]thio]methyl]-7-methoxy-8-oxo-, monosodium salt, (6R,7R)-
• 5-Oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[[(difluoromethyl)thio]acetyl]amino]-3-[[[1-(2-hydroxyethyl)-1H-tetrazol-5-yl]thio]methyl]-7-methoxy-8-oxo-, monosodium salt, (6R-cis)-
• 5-Oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[[(difluoromethyl)thio]acetyl]amino]-3-[[[1-(2-hydroxyethyl)-1H-tetrazol-5-yl]thio]methyl]-7-methoxy-8-oxo-, sodium salt (1:1), (6R,7R)-
• 6315 S Shionogi
• 6315S
• Flomoxef sodium salt
• Flumarin
• sodium (6R,7R)-7-({[(difluoromethyl)sulfanyl]acetyl}amino)-3-({[1-(2-hydroxyethyl)-1H-tetrazol-5-yl]sulfanyl}methyl)-7-methoxy-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

Flomoxef sodium

CAS: 92823-03-5

Formula: C₁₅H₁₇F₂N₆NaO₇S₂

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 518.4481

Ref: IN-DA00GRA2

Flomoxef Sodium Salt

CAS: 92823-03-5

Formula: C₁₅H₁₇F₂N₆O₇S₂·Na

Colore e forma: White To Off-White Solid

Peso molecolare: 495.45 22.99

Ref: 4Z-F-107001

Flomoxef Sodium

Prodotto controllato

CAS: 92823-03-5

Stability Hygroscopic
Applications Flomoxef Sodium is a sodium salt derivative of Flomoxef (F401850); an oxacephem derived beta-lactam antibiotic that is particularly effective against gram-positive bacteria.
References Miwa, H. et al.: Chemotherapy, 35, 121 (1987); Mikamo, H. et al.: Curr. Therap. Res., 56, 873 (1995);

Formula: C₁₅H₁₇F₂N₆NaO₇S₂

Colore e forma: Neat

Peso molecolare: 518.45

Ref: TR-F403000

Flomoxef Sodium - Bio-X ™

CAS: 92823-03-5

Flomoxef sodium is a water-soluble second/fourth-generation cephalosporin, Shionogi β-lactam antibiotic. Flomoxef inhibits bacterial growth through inhibition of cell wall biosynthesis. It has been shown to be effective against infections caused by Streptococcus pneumoniae, Enterobacter aerogenes, and Acinetobacter baumannii among other bacteria, and can be used to treat ongoing infections or as a prophylactic for example ahead of surgery. Flomoxef sodium has been shown to have synergistic effects when used in combination with isepamicin sulfate and penicillin, which may be due to its ability to increase the permeability of the bacterial cell membrane. Clinical trials are currently underway for flomoxef sodium as a treatment for MRSA infections and UTIs. 
Flomoxef Sodium is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.

Formula: C₁₅H₁₈F₂N₆O₇S₂•Na

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 519.46 g/mol

Ref: 3D-BF300080

Flomoxef Sodium

CAS: 92823-03-5

Flomoxef sodium is a water-soluble prodrug with antibacterial activity that is converted to the active form, flomoxef. Flomoxef sodium inhibits bacterial growth by binding to penicillin-binding proteins and inhibiting cell wall synthesis. It has been shown to be effective against infections caused by Streptococcus pneumoniae, Enterobacter aerogenes, and Acinetobacter baumannii. Flomoxef sodium has been shown to have synergistic effects when used in combination with isepamicin sulfate and penicillin, which may be due to its ability to increase the permeability of the bacterial cell membrane. Clinical trials are currently underway for flomoxef sodium as a treatment for MRSA infections.

Formula: C₁₅H₁₇F₂N₆NaO₇S₂

Colore e forma: White Powder

Peso molecolare: 518.45 g/mol

Ref: 3D-FF41634

Flomoxef sodium

CAS: 92823-03-5

Flomoxef sodium, an antibiotic belonging to the oxacephem group, exhibits excellent activity against a broad spectrum of Gram-positive bacteria.

Formula: C₁₅H₁₇F₂N₆NaO₇S₂

Purezza: 99.28%

Colore e forma: Solid

Peso molecolare: 518.44

Ref: TM-T11301L

Flomoxef Sodium Salt

CAS: 92823-03-5

Formula: C₁₅H₁₇F₂N₆O₇S₂Na

Peso molecolare: 495.45 : 23.0

Ref: ST-EA-CP-F143003