![(2E)-3-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-2-propenal](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fcas-image%2Fthumb-webp%2F29681-2e-3-3-4-fluorophenyl-1-1-methylethyl-1h-indol-2-yl-2-propenal.webp&w=3840&q=75)
CAS 93957-50-7
:(2E)-3-[3-(4-fluorofenil)-1-(1-metiletil)-1H-indol-2-il]-2-propenale
Descrizione:
La sostanza chimica nota come (2E)-3-[3-(4-fluorofenil)-1-(1-metiletil)-1H-indol-2-il]-2-propenale, con numero CAS 93957-50-7, è caratterizzata dalla sua struttura complessa, che include un moiety di indolo e un gruppo funzionale propenale. Questo composto presenta un gruppo fluorofenile, che contribuisce alla sua potenziale attività biologica e lipofilia. La presenza del gruppo isopropile sull'anello di indolo migliora le sue proprietà steriche, influenzando possibilmente le sue interazioni con obiettivi biologici. La parte propenale della molecola indica che potrebbe partecipare a varie reazioni chimiche, comprese le addizioni di Michael o le addizioni coniugate, a causa della presenza del sistema carbonilico α,β-insaturo. Questo composto potrebbe mostrare interessanti proprietà farmacologiche, rendendolo un argomento di interesse nella chimica medicinale e nello sviluppo di farmaci. Le sue caratteristiche specifiche, come solubilità, stabilità e reattività, dipenderebbero dalle condizioni circostanti e dalla presenza di altri gruppi funzionali in un dato ambiente.
Formula:C20H18FNO
InChI:InChI=1S/C20H18FNO/c1-14(2)22-18-7-4-3-6-17(18)20(19(22)8-5-13-23)15-9-11-16(21)12-10-15/h3-14H,1-2H3/b8-5+
InChI key:InChIKey=DVWHSTKQJBIYCK-VMPITWQZSA-N
SMILES:C(=C/C=O)\C1=C(C=2C(N1C(C)C)=CC=CC2)C3=CC=C(F)C=C3
Sinonimi:- (2E)-3-[3-(4-Fluorophenyl)-1-(1-Methylethyl)-1H-Indol-2-Yl]-2-Propenal
- (E)-3-(3-(4-Fluorophenyl)-1-isopropyl-1H-indol-2-yl)acrylaldehyde
- (E)-3-[3'-(4''-Fluorophenyl)-1'-(1''-Methylethyl)-1H-Indol-2''-Yl]-2-Propnal
- (E)-3-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-2-propenal
- (E)-3-[3-(4-fluorophenyl)-1-(1-methylethyl)-2-indolyl]propenal
- 2-Propenal, 3-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-, (2E)-
- 2-Propenal,3-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-, (E)-
- Fluvastatin intermediate
Ordinare per
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9 prodotti.
(E)-3-[3-(4-Fluorophenyl)-1-isopropylindol-2-yl]acrolein
CAS:Formula:C20H18FNOPurezza:>98.0%(GC)Colore e forma:Light orange to Yellow to Green powder to crystalPeso molecolare:307.372-Propenal, 3-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-, (2E)-
CAS:Formula:C20H18FNOPurezza:98%Colore e forma:SolidPeso molecolare:307.3614(E)-3-(3-(4-Fluorophenyl)-1-isopropyl-1H-indol-2-yl)acrylaldehyde
CAS:(E)-3-(3-(4-Fluorophenyl)-1-isopropyl-1H-indol-2-yl)acrylaldehydePurezza:98%Peso molecolare:307.37g/mol(E)-3-[3'-(4''-fluorophenyl)-1'-(1''-methylethyl)-1H-indol-2''-yl]-2-propnal
CAS:(E)-3-[3'-(4''-Fluorophenyl)-1'-(1''-methylethyl)-1H-indol-2''-yl]-2-propnal is an amoebicidal agent that belongs to the class of indole derivatives. It has been shown to inhibit tumor growth in animal models, and thus may be a potential anti-cancer drug. The activity index of (E)-3-[3'-(4''-fluorophenyl)-1'-(1''-methylethyl)-1H-indol-2''-yl]-2-propnal was significantly lower than those of fenoldopam, a well known antihypertensive agent, for the treatment of liver cancer. The compound also inhibits the growth of bacteria by inhibiting protein synthesis in organisms such as amoeba.Formula:C20H18FNOPurezza:Min. 95%Colore e forma:Yellow PowderPeso molecolare:307.36 g/mol(E)-3-(3-(4-Fluorophenyl)-1-isopropyl-1H-indol-2-yl)acrylaldehyde-d7
CAS:Prodotto controllatoApplications (E)-3-(3-(4-Fluorophenyl)-1-isopropyl-1H-indol-2-yl)acrylaldehyde-d7 an isotope labelled reactant used in the synthesis of Fluvastatin (F601250), a synthetic HMG-CoA reductase inhibitor.
References Sacharia, J.R., et. al.: J. Org. Chem., 75, 7514 (2010); Kim, A., Kim, I.S.: Bull. Korean Chem. Soc., 32, 3748 (2011); Yuan, J., et al.: Atherosclerosis, 87, 147 (1991); Tse, F.L.S., et al.: J. Clin. Pharmacol., 32, 630 (1992); Dain, J.G., et al.: Drug Metab. Disposit., 21, 567 (1993)Formula:C20D7H11FNOColore e forma:NeatPeso molecolare:314.405(E)-3-[3-(4-Fluorophenyl)-1-isopropyl-1H-indol-2-yl]-propenal
CAS:Formula:C20H18FNOPurezza:98%Colore e forma:SolidPeso molecolare:307.368(E)-3-(3-(4-Fluorophenyl)-1-isopropyl-1H-indol-2-yl)acrylaldehyde
CAS:Prodotto controllatoFormula:C20H18FNOColore e forma:NeatPeso molecolare:307.36
![(E)-3-[3-(4-Fluorophenyl)-1-isopropylindol-2-yl]acrolein](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3B%2Fthumb%2FF0819.jpg&w=3840&q=75)
![2-Propenal, 3-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-, (2E)-](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA003C0F.jpg&w=3840&q=75)
![(E)-3-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]prop-2-enal](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F86%2Fthumb%2FMM0676.14-0025.jpg&w=3840&q=75)
![(E)-3-[3'-(4''-fluorophenyl)-1'-(1''-methylethyl)-1H-indol-2''-yl]-2-propnal](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3D%2Fthumb%2FFF37514.jpg&w=3840&q=75)
![(E)-3-[3-(4-Fluorophenyl)-1-isopropyl-1H-indol-2-yl]-propenal](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb%2FF036562.jpg&w=3840&q=75)
