CAS 93957-55-2
:Fluvastatina sodica
Descrizione:
Fluvastatina sodica è un agente sintetico per la riduzione dei lipidi che appartiene alla classe delle statine, utilizzato principalmente per gestire l'iperlipidemia e ridurre il rischio di malattie cardiovascolari. Funziona come un inibitore della HMG-CoA reduttasi, che gioca un ruolo cruciale nella biosintesi del colesterolo. Il composto è caratterizzato dalla sua capacità di ridurre i livelli di colesterolo LDL (lipoproteine a bassa densità) mentre aumenta modestamente il colesterolo HDL (lipoproteine ad alta densità). Fluvastatina sodica è tipicamente somministrato per via orale ed è ben assorbito nel tratto gastrointestinale, sebbene la sua biodisponibilità sia influenzata dal metabolismo di primo passaggio nel fegato. Il farmaco è generalmente ben tollerato, ma gli effetti collaterali potenziali possono includere dolore muscolare, anomalie degli enzimi epatici e disturbi gastrointestinali. È controindicato in pazienti con malattia epatica attiva o in quelli che sono in gravidanza o in allattamento. Fluvastatina sodica è spesso prescritto insieme a modifiche dietetiche e cambiamenti nello stile di vita per migliorare la sua efficacia nella gestione del colesterolo. Si raccomanda un monitoraggio regolare dei livelli lipidici e dei test di funzionalità epatica durante il trattamento.
Formula:C24H26FNO4·Na
InChI:InChI=1/C24H26FNO4.Na/c1-15(2)26-21-6-4-3-5-20(21)24(16-7-9-17(25)10-8-16)22(26)12-11-18(27)13-19(28)14-23(29)30;/h3-12,15,18-19,27-28H,13-14H2,1-2H3,(H,29,30);/b12-11+;/t18-,19-;/s2
InChI key:InChIKey=CUOKYGJQSIKNFS-ZADPHQEYNA-N
SMILES:C(=C/[C@@H](C[C@@H](CC(O)=O)O)O)\C1=C(C=2C(N1C(C)C)=CC=CC2)C3=CC=C(F)C=C3.[Na]
Sinonimi:- (3R,5S,6E)-rel-7-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic acid monosodium salt
- 6-Heptenoic acid, 7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-, monosodium salt, (3R,5S,6E)-rel-
- 6-Heptenoic acid, 7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-, monosodium salt, [R*,S*-(E)]-(±)-
- 6-Heptenoic acid, 7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-, sodium salt (1:1), (3R,5S,6E)-rel-
- Almastatin
- Canef
- Cranoc
- Fluindostatin
- Fluvastatin Sodium Salt
- Fractal
- Lescol
- Lescol XL
- Lochol
- Locol
- Sodium (3R,5S,6E)-7-[3-(4-Fluorophenyl)-1-(1-Methylethyl)-1H-Indol-2-Yl]-3,5-Dihydroxy-6-Heptenoate
- Vastin
- Xu 62-320
- sodium (3R,5S,6E)-7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoate
- Vedi altri sinonimi
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19 prodotti.
Fluvastatin Sodium Salt
CAS:Formula:C24H25FNNaO4Purezza:>98.0%(HPLC)(N)Colore e forma:Light orange to Yellow to Green powder to crystalPeso molecolare:433.46FLUVASTATIN SODIUM CRS
CAS:FLUVASTATIN SODIUM CRSFormula:C24H25FNNaO4Colore e forma:White. Orange. Light Yellow. Powder.Peso molecolare:433.4478FLUVASTATIN FOR SYSTEM SUITABILITY CRS
CAS:FLUVASTATIN FOR SYSTEM SUITABILITY CRSFormula:C24H25FNNaO4Peso molecolare:433.4478Fluvastatin sodium
CAS:Fluvastatin sodiumFormula:C24H25NNaO4Purezza:97.4%Colore e forma:Light Yellow. To. OrangePeso molecolare:414.16813Fluvastatin Sodium
CAS:Cardiovascular drugs, not elsewhere specified or includedFormula:C24H25FNNaO4Colore e forma:White Yellow PowderPeso molecolare:433.16653sodium (3R,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoate
CAS:Formula:C24H25FNNaO4Purezza:98%Colore e forma:SolidPeso molecolare:433.4478Fluvastatin sodium
CAS:Fluvastatin sodium (Fluvastatin sodium salt), a competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase (HMGCR), is a commonly used cholesterolFormula:C24H25FNNaO4Purezza:98.54% - 99.56%Colore e forma:Light Yellow Solid PowderPeso molecolare:433.45Fluvastatin Sodium Salt
CAS:Formula:C24H25FNO4·NaColore e forma:Yellow SolidPeso molecolare:410.47 22.99Fluvastatin-d6 Sodium Salt
CAS:Formula:C24H19D6FNO4·NaColore e forma:Off-White SolidPeso molecolare:416.50 22.99Fluvastatin sodium salt
CAS:Formula:C24H25FNO4·Na·xH2OPurezza:98.0 - 102.0 % (anhydrous basis)Colore e forma:Off-white to pale yellow or light yellow-orange powderPeso molecolare:433.45 (anhydrous)Fluvastatin sodium
CAS:Prodotto controllatoFormula:C24H25FNO4·NaColore e forma:NeatPeso molecolare:433.45Fluvastatin Sodium Salt (Relative Stereochemistry)
CAS:Stability Hygroscopic
Applications A synthetic HMG-CoA reductase inhibitor. Antilipemic.
References Yuan, J., et al.: Atherosclerosis, 87, 147 (1991), Tse, F.L.S., et al.: J. Clin. Pharmacol., 32, 630 (1992), Dain, J.G., et al.: Drug Metab. Disposit., 21, 567 (1993);Formula:C24H25FNO4·NaColore e forma:NeatPeso molecolare:433.45Fluvastatin-d6 Sodium
CAS:Prodotto controllatoApplications Fluvastatin-d6 Sodium Salt is the labeled analogue of Fluvastatin Sodium Salt (F601250), a synthetic HMG-CoA reductase inhibitor. Antilipemic.
References Yuan, J., et al.: Atherosclerosis, 87, 147 (1991), Tse, F.L.S., et al.: J. Clin. Pharmacol., 32, 630 (1992), Dain, J.G., et al.: Drug Metab. Disposit., 21, 567 (1993);Formula:C24H19D6FNNaO4Colore e forma:NeatPeso molecolare:439.48Fluvastatin sodium
CAS:Fluvastatin is a statin that lowers blood cholesterol and triglycerides by inhibiting HMG-CoA reductase, an enzyme that plays a critical role in the synthesis of cholesterol. Fluvastatin has also been shown to reduce the incidence of myocardial infarction, and to reduce atherosclerotic lesions in animal models, reducing the incidence of cardiovascular disease. Fluvastatin also has been shown to inhibit the activation of toll-like receptor 4 (TLR4) by lipopolysaccharide (LPS), which may be related to its anti-inflammatory effects. Furthermore, through lowering blood cholesterol, Fluvastatin also inhibits tubulointerstitial injury and prevents renal damage caused by high concentrations of the lipid.
Formula:C24H25FNNaO4Purezza:Min. 98%Colore e forma:Off-White PowderPeso molecolare:433.45 g/molFluvastatin sodium salt - Bio-X ™
CAS:Fluvastatin is a statin that lowers blood cholesterol and triglycerides by inhibiting HMG-CoA reductase, an enzyme that plays a critical role in the synthesis of cholesterol. Fluvastatin has also been shown to reduce the incidence of myocardial infarction, and to reduce atherosclerotic lesions in animal models, reducing the incidence of cardiovascular disease. Fluvastatin also has been shown to inhibit the activation of toll-like receptor 4 (TLR4) by lipopolysaccharide (LPS), which may be related to its anti-inflammatory effects. Furthermore, through lowering blood cholesterol, Fluvastatin also inhibits tubulointerstitial injury and prevents renal damage caused by high concentrations of the lipid.Formula:C24H25FNNaO4Purezza:Min. 98%Peso molecolare:433.45 g/mol
![sodium (3R,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoate](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA003QMD.jpg&w=3840&q=75)
