CAS 93957-55-2

Fluvastatina sodica

Descrizione:

Fluvastatina sodica è un agente sintetico per la riduzione dei lipidi che appartiene alla classe delle statine, utilizzato principalmente per gestire l'iperlipidemia e ridurre il rischio di malattie cardiovascolari. Funziona come un inibitore della HMG-CoA reduttasi, che gioca un ruolo cruciale nella biosintesi del colesterolo. Il composto è caratterizzato dalla sua capacità di ridurre i livelli di colesterolo LDL (lipoproteine a bassa densità) mentre aumenta modestamente il colesterolo HDL (lipoproteine ad alta densità). Fluvastatina sodica è tipicamente somministrato per via orale ed è ben assorbito nel tratto gastrointestinale, sebbene la sua biodisponibilità sia influenzata dal metabolismo di primo passaggio nel fegato. Il farmaco è generalmente ben tollerato, ma gli effetti collaterali potenziali possono includere dolore muscolare, anomalie degli enzimi epatici e disturbi gastrointestinali. È controindicato in pazienti con malattia epatica attiva o in quelli che sono in gravidanza o in allattamento. Fluvastatina sodica è spesso prescritto insieme a modifiche dietetiche e cambiamenti nello stile di vita per migliorare la sua efficacia nella gestione del colesterolo. Si raccomanda un monitoraggio regolare dei livelli lipidici e dei test di funzionalità epatica durante il trattamento.

Formula: C₂₄H₂₆FNO₄·Na

InChI: InChI=1/C24H26FNO4.Na/c1-15(2)26-21-6-4-3-5-20(21)24(16-7-9-17(25)10-8-16)22(26)12-11-18(27)13-19(28)14-23(29)30;/h3-12,15,18-19,27-28H,13-14H2,1-2H3,(H,29,30);/b12-11+;/t18-,19-;/s2

InChI key: InChIKey=CUOKYGJQSIKNFS-ZADPHQEYNA-N

SMILES: C(=C/[C@@H](C[C@@H](CC(O)=O)O)O)\C1=C(C=2C(N1C(C)C)=CC=CC2)C3=CC=C(F)C=C3.[Na]

Sinonimi:

• (3R,5S,6E)-rel-7-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic acid monosodium salt
• 6-Heptenoic acid, 7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-, monosodium salt, (3R,5S,6E)-rel-
• 6-Heptenoic acid, 7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-, monosodium salt, [R*,S*-(E)]-(±)-
• 6-Heptenoic acid, 7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-, sodium salt (1:1), (3R,5S,6E)-rel-
• Almastatin
• Canef
• Cranoc
• Fluindostatin
• Fluvastatin Sodium Salt
• Fractal
• Lescol
• Lescol XL
• Lochol
• Locol
• Sodium (3R,5S,6E)-7-[3-(4-Fluorophenyl)-1-(1-Methylethyl)-1H-Indol-2-Yl]-3,5-Dihydroxy-6-Heptenoate
• Vastin
• Xu 62-320
• sodium (3R,5S,6E)-7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoate

Fluvastatin Sodium Salt

CAS: 93957-54-1, 93957-55-2

Formula: C₂₄H₂₅FNNaO₄

Purezza: >98.0%(HPLC)(N)

Colore e forma: Light orange to Yellow to Green powder to crystal

Peso molecolare: 433.46

Ref: 3B-F0820

Fluvastatin Sodium

CAS: 93957-55-2

Colore e forma: Neat

Ref: 61-FOR0676.00

FLUVASTATIN SODIUM CRS

CAS: 93957-55-2

FLUVASTATIN SODIUM CRS

Formula: C₂₄H₂₅FNNaO₄

Colore e forma: White. Orange. Light Yellow. Powder.

Peso molecolare: 433.4478

Ref: 41-Y0001090

FLUVASTATIN FOR SYSTEM SUITABILITY CRS

CAS: 93957-55-2

FLUVASTATIN FOR SYSTEM SUITABILITY CRS

Formula: C₂₄H₂₅FNNaO₄

Peso molecolare: 433.4478

Ref: 41-Y0001082

Fluvastatin sodium

CAS: 93957-55-2

Fluvastatin sodium

Formula: C₂₄H₂₅NNaO₄

Purezza: 97.4%

Colore e forma: Light Yellow. To. Orange

Peso molecolare: 414.16813

Ref: 47-1163

Fluvastatin Sodium

CAS: 93957-55-2

Cardiovascular drugs, not elsewhere specified or included

Formula: C₂₄H₂₅FNNaO₄

Colore e forma: White Yellow Powder

Peso molecolare: 433.16653

Ref: 45-1285931

sodium (3R,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoate

CAS: 93957-55-2

Formula: C₂₄H₂₅FNNaO₄

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 433.4478

Ref: IN-DA003QMD

Fluvastatin sodium

CAS: 93957-55-2

Fluvastatin sodium (Fluvastatin sodium salt), a competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase (HMGCR), is a commonly used cholesterol

Formula: C₂₄H₂₅FNNaO₄

Purezza: 98.54% - 99.56%

Colore e forma: Light Yellow Solid Powder

Peso molecolare: 433.45

Ref: TM-T1487

Fluvastatin Sodium Salt

CAS: 93957-55-2

Formula: C₂₄H₂₅FNO₄·Na

Colore e forma: Yellow Solid

Peso molecolare: 410.47 22.99

Ref: 4Z-F-101

Fluvastatin sodium

CAS: 93957-55-2

Fluvastatin sodium

Purezza: ≥98%

Peso molecolare: 433.45g/mol

Ref: 54-BUP13738

Fluvastatin-d6 Sodium Salt

CAS: 93957-55-2

Formula: C₂₄H₁₉D₆FNO₄·Na

Colore e forma: Off-White Solid

Peso molecolare: 416.50 22.99

Ref: 4Z-F-102

Fluvastatin sodium salt

CAS: 93957-55-2

Formula: C₂₄H₂₅FNO₄·Na·xH₂O

Purezza: 98.0 - 102.0 % (anhydrous basis)

Colore e forma: Off-white to pale yellow or light yellow-orange powder

Peso molecolare: 433.45 (anhydrous)

Ref: 7W-GP9431

Fluvastatin sodium

Prodotto controllato

CAS: 93957-55-2

Formula: C₂₄H₂₅FNO₄·Na

Colore e forma: Neat

Peso molecolare: 433.45

Ref: 04-C13871000

Fluvastatin Sodium

CAS: 93957-55-2

Colore e forma: Neat

Ref: 86-MM0676.00

Fluvastatin sodium

CAS: 93957-55-2

Fluvastatin sodium

Purezza: 98%

Peso molecolare: 433.45g/mol

Ref: 54-BISN0143

Fluvastatin Sodium Salt(Relative Stereochemistry)

CAS: 93957-55-2

Stability Hygroscopic
Applications A synthetic HMG-CoA reductase inhibitor. Antilipemic.
References Yuan, J., et al.: Atherosclerosis, 87, 147 (1991), Tse, F.L.S., et al.: J. Clin. Pharmacol., 32, 630 (1992), Dain, J.G., et al.: Drug Metab. Disposit., 21, 567 (1993);

Formula: C₂₄H₂₅FNO₄·Na

Colore e forma: Neat

Peso molecolare: 433.45

Ref: TR-F601250

Fluvastatin-d6 Sodium

Prodotto controllato

CAS: 93957-55-2

Applications Fluvastatin-d6 Sodium Salt is the labeled analogue of Fluvastatin Sodium Salt (F601250), a synthetic HMG-CoA reductase inhibitor. Antilipemic.
References Yuan, J., et al.: Atherosclerosis, 87, 147 (1991), Tse, F.L.S., et al.: J. Clin. Pharmacol., 32, 630 (1992), Dain, J.G., et al.: Drug Metab. Disposit., 21, 567 (1993);

Formula: C₂₄H₁₉D₆FNNaO₄

Colore e forma: Neat

Peso molecolare: 439.48

Ref: TR-F601253

Fluvastatin sodium

CAS: 93957-55-2

Fluvastatin is a statin that lowers blood cholesterol and triglycerides by inhibiting HMG-CoA reductase, an enzyme that plays a critical role in the synthesis of cholesterol. Fluvastatin has also been shown to reduce the incidence of myocardial infarction, and to reduce atherosclerotic lesions in animal models, reducing the incidence of cardiovascular disease. Fluvastatin also has been shown to inhibit the activation of toll-like receptor 4 (TLR4) by lipopolysaccharide (LPS), which may be related to its anti-inflammatory effects. Furthermore, through lowering blood cholesterol, Fluvastatin also inhibits tubulointerstitial injury and prevents renal damage caused by high concentrations of the lipid.

Formula: C₂₄H₂₅FNNaO₄

Purezza: Min. 98%

Colore e forma: Off-White Powder

Peso molecolare: 433.45 g/mol

Ref: 3D-FF23520

Fluvastatin sodium salt - Bio-X ™

CAS: 93957-55-2

Fluvastatin is a statin that lowers blood cholesterol and triglycerides by inhibiting HMG-CoA reductase, an enzyme that plays a critical role in the synthesis of cholesterol. Fluvastatin has also been shown to reduce the incidence of myocardial infarction, and to reduce atherosclerotic lesions in animal models, reducing the incidence of cardiovascular disease. Fluvastatin also has been shown to inhibit the activation of toll-like receptor 4 (TLR4) by lipopolysaccharide (LPS), which may be related to its anti-inflammatory effects. Furthermore, through lowering blood cholesterol, Fluvastatin also inhibits tubulointerstitial injury and prevents renal damage caused by high concentrations of the lipid.

Formula: C₂₄H₂₅FNNaO₄

Purezza: Min. 98%

Peso molecolare: 433.45 g/mol

Ref: 3D-BF164477