CAS: 943319-70-8 - Ponatinib

Formula: C₂₉H₂₇F₃N₆O

InChI: InChI=1S/C29H27F3N6O/c1-20-5-6-22(16-21(20)8-10-25-18-33-27-4-3-11-34-38(25)27)28(39)35-24-9-7-23(26(17-24)29(30,31)32)19-37-14-12-36(2)13-15-37/h3-7,9,11,16-18H,12-15,19H2,1-2H3,(H,35,39)

InChI key: InChIKey=PHXJVRSECIGDHY-UHFFFAOYSA-N

SMILES: O=C(NC1=CC=C(C(=C1)C(F)(F)F)CN2CCN(C)CC2)C3=CC=C(C(C#CC4=CN=C5C=CC=NN45)=C3)C

Sinonimi:

• 3-(2-Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]benzamide
• Ap 24534
• Ap24534
• Benzamide, 3-(2-imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-
• Iclusig

Ponatinib

CAS: 1114544-31-8 943319-70-8

• Formula: C₂₉H₂₇F₃N₆O
• Colore e forma: Pale Yellow Solid
• Peso molecolare: 523.57

Ponatinib

CAS: 943319-70-8

• Formula: C₂₉H₂₇F₃N₆O
• Purezza: ≥ 98.0%
• Colore e forma: White or off-white powder or crystals
• Peso molecolare: 532.56

Ponatinib, Free Base

CAS: 943319-70-8

• Formula: C₂₉H₂₇F₃N₆O
• Purezza: 98%
• Colore e forma: off-white crystalline solid
• Peso molecolare: 532.56g/mol

Ponatinib

CAS: 943319-70-8

Ponatinib (AP24534) is an orally available, multitargeted kinase inhibitor (IC50s: 0.37/1.1/1.5/2.2/5.4 nM for Abl, PDGFRα, …

• Formula: C₂₉H₂₇F₃N₆O
• Purezza: 98% - 99.74%
• Colore e forma: Solid
• Peso molecolare: 532.56

Ponatinib

CAS: 943319-70-8

Applications Ponatinib is a tyrosine kinase inhibitors (TKI) and used to treat chronic myeloid leukemia …

• Formula: C₂₉H₂₇F₃N₆O
• Colore e forma: Off-White
• Peso molecolare: 532.56

Ponatinib

CAS: 943319-70-8

BCR-ABL1 tyrosine kinase inhibitor

• Formula: C₂₉H₂₇F₃N₆O
• Purezza: Min. 95%
• Colore e forma: Powder
• Peso molecolare: 532.56 g/mol

Ponatinib N-Glucuronide

CAS: 943319-70-8

• Formula: C₃₅H₃₅F₃N₆O₇
• Colore e forma: Neat
• Peso molecolare: 709.692