CAS 944-73-0

Acido 1,3-dimetilurico

Descrizione:

Acido 1,3-dimetilurico è un derivato della purina e una forma metilata dell'acido urico, caratterizzato dalla presenza di due gruppi metilici attaccati agli atomi di azoto nelle posizioni 1 e 3 della struttura dell'acido urico. La sua formula molecolare è C7H8N4O3 e ha un peso molecolare che riflette la sua composizione di carbonio, idrogeno, azoto e ossigeno. Questo composto è tipicamente un solido cristallino bianco a bianco sporco, che mostra solubilità in solventi polari come acqua e alcoli, comune a molti derivati dell'acido urico. Acido 1,3-dimetilurico è di interesse nella ricerca biochimica, in particolare negli studi relativi al metabolismo delle purine e alle sue potenziali implicazioni in vari processi fisiologici. Le sue modifiche strutturali possono influenzare la sua attività biologica e le interazioni con gli enzimi coinvolti nel metabolismo degli acidi nucleici. Come molti composti contenenti azoto, può mostrare deboli proprietà acide, contribuendo al suo comportamento nei sistemi biologici. I dati di sicurezza devono essere consultati per le linee guida di manipolazione ed esposizione, come per qualsiasi sostanza chimica.

Formula: C₇H₈N₄O₃

InChI: InChI=1S/C7H8N4O3/c1-10-4-3(8-6(13)9-4)5(12)11(2)7(10)14/h1-2H3,(H2,8,9,13)

InChI key: InChIKey=OTSBKHHWSQYEHK-UHFFFAOYSA-N

SMILES: O=C1C2=C(N(C)C(=O)N1C)NC(=O)N2

Sinonimi:

• 1,3-Dimethyl-2,6,8-Trioxopurine
• 1,3-Dimethyl-7,9-dihydro-3H-purine-2,6,8-trione
• 1,3-Dimethyl-7,9-dihydropurine-2,6,8-trione
• 1,3-Dimethyluric acid
• 1,3-dimethyl-7,9-dihydro-1H-purine-2,6,8(3H)-trione
• 1H-Purine-2,6,8(3H)-trione, 7,9-dihydro-1,3-dimethyl-
• Ba 2751
• Brn 0193698
• Nsc 95854
• Oxytheophylline
• Uric acid, 1,3-dimethyl-
• Uric acid, 1,3-dimethyl- (VAN)
• 7,9-Dihydro-1,3-dimethyl-1H-purine-2,6,8(3H)-trione
• 7,9-Dihydro-1,3-dimethyl-1H-purine-2,6,8(3H)-trione

1,3-Dimethyluric acid

CAS: 944-73-0

Formula: C₇H₈N₄O₃

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 196.1634

Ref: IN-DA0039GL

1,3-Dimethyluric acid

CAS: 944-73-0

1,3-Dimethyluric acid

Purezza: ≥98%

Peso molecolare: 196.16g/mol

Ref: 54-BUP14718

1,3-Dimethyluric acid

CAS: 944-73-0

Formula: C₇H₈N₄O₃

Purezza: ≥ 98%

Colore e forma: White, off-white or light-yellow powder

Peso molecolare: 196.16

Ref: 7W-GL2263

Theophylline EP Impurity E

CAS: 944-73-0

Formula: C₇H₈N₄O₃

Colore e forma: White To Off-White Solid

Peso molecolare: 196.17

Ref: 4Z-T-608

1,3-Dimethyl-1H-Purine-2,6,8(3H,7H,9H)-Trione

CAS: 944-73-0

1,3-Dimethyl-1H-Purine-2,6,8(3H,7H,9H)-Trione

Purezza: 98%

Peso molecolare: 196.16g/mol

Ref: 54-OR1009200

1,3-Dimethyluric Acid

CAS: 944-73-0

Formula: C₇H₈N₄O₃

Purezza: >98.0%(T)(HPLC)

Colore e forma: White to Light yellow powder to crystal

Peso molecolare: 196.17

Ref: 3B-D6169

1,3-Dimethyluric acid

CAS: 944-73-0

1,3-Dimethyluric acid is a product of theophylline metabolism in man. It is one of the purine components in urinary calculi.

Formula: C₇H₈N₄O₃

Purezza: 99.84% - 99.94%

Colore e forma: Solid

Peso molecolare: 196.16

Ref: TM-T8075

1,3-Dimethyluric Acid

Prodotto controllato

CAS: 944-73-0

Applications 1,3-Dimethyluric Acid, is a metabolite of Caffeine (C080100), that is shown to have some of Its similar effects.
References Kalow, W., et al.: Clin. Pharmacol. Ther., 53, 503 (1993), Sharma, S., et al.: Cancer Res., 54, 5848 (1994), Sugawara, M., et al.: J. Biol. Chem., 275, 16473 (2000), Takeda, M., et al.: J. Pharmacol. Exp. Ther., 302, 666 (2002),

Formula: C₇H₈N₄O₃

Colore e forma: Neat

Peso molecolare: 196.16

Ref: TR-D479735

Theophylline EP Impurity E

CAS: 944-73-0

Formula: C₇H₈N₄O₃

Peso molecolare: 196.17

Ref: ST-EA-CP-T59005

1,3-Dimethyl-1H-purine-2,6,8(3H,7H,9H)-trione

CAS: 944-73-0

Formula: C₇H₈N₄O₃

Purezza: 97%

Peso molecolare: 196.166

Ref: 10-F517648

1,3-Dimethyluric acid

Prodotto controllato

CAS: 944-73-0

1,3-Dimethyluric acid is a metabolite of caffeine. It is formed by the oxidative deamination of 1,3-dimethylxanthine in the liver. The concentrations of 1,3-dimethyluric acid are elevated in patients with chronic renal failure and those who are taking theophylline. The concentration–time curve for 1,3-dimethyluric acid was found to be linear and predictable after intravenous administration of caffeine at a dose of 10 mg/kg body weight in rats. This suggests that it is possible to estimate the rate of elimination from plasma after intravenous dosing with caffeine based on measurements of plasma concentrations and time. The metabolism of caffeine involves two pathways: oxidative deamination (1,3-dimethyluric acid) and demethylation (paraxanthine). It has been shown that the metabolites 1,3-dimethyluric acid and paraxanthine are formed by different metabolic pathways. The

Formula: C₇H₈N₄O₃

Purezza: Min. 98 Area-%

Colore e forma: White Powder

Peso molecolare: 196.16 g/mol

Ref: 3D-FD08003