CAS 94790-37-1

1-[Bis(dimetilammino)metilene]-1H-benzotriazolio esafluorofosfato(1-) 3-ossido

Descrizione:

1-[Bis(dimetilammino)metilene]-1H-benzotriazolio esafluorofosfato(1-) 3-ossido, comunemente riferito dal suo numero CAS 94790-37-1, è un composto chimico che presenta un moiety di benzotriazolo, noto per le sue applicazioni in vari campi, tra cui la sintesi organica e la scienza dei materiali. Questo composto è caratterizzato dalla sua struttura unica che include un gruppo bis(dimetilamino)methylene, contribuendo alla sua reattività e potenziale come agente nucleofilo. La presenza dell'anione esafluorofosfato indica forti interazioni ioniche, che possono migliorare la solubilità in solventi polari. Inoltre, il gruppo funzionale 3-ossido può conferire proprietà elettroniche specifiche, rendendolo utile in applicazioni fotocatalitiche. Il composto è tipicamente maneggiato con cura a causa della sua potenziale tossicità e reattività, ed è spesso utilizzato in ambienti di laboratorio controllati. Le sue applicazioni possono estendersi a settori come la catalisi, la sintesi di coloranti e come reagente in trasformazioni organiche, dimostrando la sua versatilità nella ricerca e nello sviluppo chimico.

Formula: C₁₁H₁₆N₅O·F₆P

InChI: InChI=1S/C11H16N5O.F6P/c1-13(2)11(14(3)4)15-9-7-5-6-8-10(9)16(17)12-15;1-7(2,3,4,5)6/h5-8H,1-4H3;/q+1;-1

InChI key: InChIKey=BSKUEERROYGAFF-UHFFFAOYSA-N

SMILES: C(N(C)C)(N(C)C)=[N+]1C=2C(N(=O)=N1)=CC=CC2.[P+5]([F-])([F-])([F-])([F-])([F-])[F-]

Sinonimi:

• 1-[Bis(dimethylamino)methylene]-1H-benzotriazolium hexafluorophosphate(1-) 3-oxide
• 1H-Benzotriazolium, 1-[bis(dimethylamino)methylene]-, 3-oxide, hexafluorophosphate(1-) (1:1)
• 1H-Benzotriazolium, 1-[bis(dimethylamino)methylene]-, hexafluorophosphate(1-), 3-oxide
• 2-(1H-Benzotriazole-1-Yl)-1,1,3,3-Tetramethyluronium Hexafluorophosphate
• Hbtu
• N-Hbtu
• N-[(1H-benzotriazol-1-yloxy)(dimethylamino)methylidene]-N-methylmethanaminium hexafluorophosphate
• O-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium Hexafluorophosphate
• O-Benzotriazole-N,N,N',N'-tetramethyl-uronium-hexafluoro-phosphate
• O-Benzotriazole-N,N,N',N'-tetramethyl-uronium-hexafluorophosphate

HBTU [Coupling Reagent for Peptide]

CAS: 94790-37-1

Formula: C₁₁H₁₆F₆N₅OP

Purezza: >98.0%(HPLC)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 379.25

Ref: 3B-B1657

1-(Bis(dimethylamino)methylene)-1H-benzo[d][1,2,3]triazole-1-ium 3-oxide hexafluorophosphate(V), 98%

CAS: 94790-37-1

Formula: C11H16F6N5OP

Colore e forma: White - Almost white crystal - Powde

Peso molecolare: 379.24

Ref: BD-BD23222

O-(Benzotriazol-1-yl)-N,N,N’,N’-tetramethyluronium hexafluorophosphate

CAS: 94790-37-1

Formula: C₁₁H₁₆F₆N₅OP

Purezza: 99.0%

Colore e forma: Solid, Powder or Crystalline Powder or Solid

Peso molecolare: 379.247

Ref: 10-F009019

O-(1H-Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate, 98%

CAS: 94790-37-1

O-(1H-Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate is used as a coupling reagent for solid-phase peptide synthesis. It has been shown to effectively suppress racemization. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. S

Formula: C₁₁H₁₆N₅O

Purezza: 98%

Colore e forma: Crystalline powder, White to pale cream

Peso molecolare: 234.28

Ref: 02-B23597

O-Benzotriazol-1-yl-N,N,N',N'-tetramethyluronium hexafluorophosphate

CAS: 94790-37-1

Formula: C₁₁H₁₆F₆N₅OP

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 379.2418

Ref: IN-DA0035F7

HBTU

CAS: 94790-37-1

Formula: C₁₁H₁₆F₆N₅OP

Purezza: ≥ 99.0%

Colore e forma: White to almost white powder or crystals

Peso molecolare: 379.25

Ref: 7W-GE0864

O-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate

CAS: 94790-37-1

O-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate

Formula: C₁₁H₁₆N₅O·PF₆

Purezza: ≥95%

Colore e forma: white crystals

Peso molecolare: 379.24181g/mol

Ref: 54-PC6587

HBTU

CAS: 94790-37-1

HBTU is a common reagent used for peptide coupling, which can be employed for amide and ester formation. It is stable, highly reactive, suitable for solid phase and in-solution synthesis. The major advantages of HBTU are high yields, fast reaction times, easy reaction conditions, racemisation control and ease of purification from the water-soluble by-products. HBTU contains both the carbodiimide function and the benzotriazole one, activating the carboxylic acid and forming HOBt in situ. Although HBTU was originally catalogued as uronium salt, X-ray diffraction showed evidence for it to be an aminium salt instead.

Formula: C₁₁H₁₆F₆N₅OP

Purezza: Min. 99 Area-%

Peso molecolare: 379.24 g/mol

Ref: 3D-Z-1021

HBTU Reagent

CAS: 94790-37-1

HBTU is a reagent that is used in the synthesis of peptides. It has been shown to have inhibitory properties and stable complexes with ester linkages. HBTU has been shown to have a negative effect on congestive heart disease, which may be due to its ability to bind to receptors and mimic the effects of peptide hormones. This compound is also used as a model system for mitochondrial membrane potential. HBTU binds covalently to the peptide hormone receptor, which slows down the rate of degradation and increases its resistance to proteases. HBTU can also be used as an immunosuppressant drug in animal models of autoimmune diseases by inhibiting T-cell proliferation and cytokine production.

Formula: C₁₁H₁₆N₅OPF₆

Purezza: Min. 95%

Peso molecolare: 379.25 g/mol

Ref: 3D-KHB-1065-PI

HBTU

CAS: 94790-37-1

HBTU is a common reagent used for peptide coupling, which can be employed for amide and ester formation. It is stable, highly reactive, suitable for solid phase and in-solution synthesis. The major advantages of HBTU are high yields, fast reaction times, easy reaction conditions, racemisation control and ease of purification from the water-soluble by-products. HBTU contains both the carbodiimide function and the benzotriazole one, activating the carboxylic acid and forming HOBt in situ. Although HBTU was originally catalogued as uronium salt, X-ray diffraction showed evidence for it to be an aminium salt instead.

Formula: C₁₁H₁₆F₆N₅OP

Purezza: Min. 99 Area-%

Colore e forma: White Powder

Peso molecolare: 379.24 g/mol

Ref: 3D-FH07095

HBTU extrapure, 98%

CAS: 94790-37-1

Formula: C₁₁H₁₆F₆N₅OP

Purezza: min. 98 %

Colore e forma: White, Crystalline powder

Peso molecolare: 379.25

Ref: SR-44424

HBTU

CAS: 94790-37-1

Applications HBTU is a coupling reagent used in peptide synthesis. HBTU has been shown to effectively suppress racemization.
References Prasad, K.V.S.R.G. et al.: Int. J. Pharm. Sci. Rev. Res., 8, 108 (2011); Van Den Nest, W, et al.: J. Pep. Sci., 7, 115 (2001);

Formula: C₁₁H₁₆F₆N₅OP

Colore e forma: White To Off-White

Peso molecolare: 379.24

Ref: TR-H107500