CAS 951-78-0

Desossiuridina

Descrizione:

Desossiuridina è un nucleoside che gioca un ruolo cruciale nella sintesi del DNA. Consiste in una molecola di zucchero desossiribosio legata a una base di uracile, che è una delle quattro nucleobasi presenti nell'RNA, ma nel DNA è sostituita dalla timina. La formula chimica di Desossiuridina è C9H11N2O5, e ha un peso molecolare di circa 227,24 g/mol. Desossiuridina è tipicamente una polvere cristallina bianca a bianco sporco che è solubile in acqua e presenta un pH leggermente acido a neutro in soluzione. È coinvolto in vari processi biochimici, inclusa la replicazione e riparazione del DNA, e funge da substrato per l'enzima timidina chinasi, che lo fosforila per formare Desossiuridina trifosfato (dUTP). Questo composto è anche di interesse nella ricerca e nelle applicazioni terapeutiche, in particolare nello studio del metabolismo degli acidi nucleici e come potenziale agente antivirale. Il suo numero CAS è 951-78-0, che lo identifica in modo univoco nei database chimici.

Formula: C₉H₁₂N₂O₅

InChI: InChI=1S/C9H12N2O5/c12-4-6-5(13)3-8(16-6)11-2-1-7(14)10-9(11)15/h1-2,5-6,8,12-13H,3-4H2,(H,10,14,15)/t5-,6+,8+/m0/s1

InChI key: InChIKey=MXHRCPNRJAMMIM-SHYZEUOFSA-N

SMILES: O=C1N([C@@H]2O[C@H](CO)[C@@H](O)C2)C=CC(=O)N1

Sinonimi:

• 1-(2-Deoxy-β-<span class="text-smallcaps">D</span>-erythro-pentofuranosyl)uracil
• 1-(2-Deoxy-β-D-erythro-pentofuranosyl)uracil
• 1-(2-deoxy-alpha-L-erythro-pentofuranosyl)pyrimidine-2,4(1H,3H)-dione
• 1-(2-deoxy-beta-L-erythro-pentofuranosyl)pyrimidine-2,4(1H,3H)-dione
• 1-(2-deoxypentofuranosyl)pyrimidine-2,4(1H,3H)-dione
• 1-[(3xi)-2-deoxy-beta-D-glycero-pentofuranosyl]pyrimidine-2,4(1H,3H)-dione
• 2'-Desoxiuridina
• 2'-Desoxyuridin
• 2'-Desoxyuridine
• 2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-β-<span class="text-smallcaps">D</span>-erythro-pentofuranosyl)-
• 2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-β-<span class="text-smallcaps">D</span>-ribofuranosyl)-
• 2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-β-D-erythro-pentofuranosyl)-
• 2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-β-D-ribofuranosyl)-
• Deoxyribose uracil
• Deoxyuridine
• Nsc 23615
• Uracil deoxyriboside
• Uridine, 2'-deoxy-
• 2-Deoxyuridine

2'-Deoxyuridine

CAS: 951-78-0

Formula: C₉H₁₂N₂O₅

Purezza: >99.0%(HPLC)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 228.20

Ref: 3B-D0060

2'-Deoxyuridine, 98+%

CAS: 951-78-0

2'-Deoxyuridine is frequently halogenated to create thymidine analogues useful for studies of DNA synthesis and degradation mechanisms. Derivatized 2?-Deoxyuridines used as labeling substrates include chloro-2?-deoxyuridine (CldU), bromodeoxyuridine (BrdU) and/or iododeoxyuridine (IdU). Other useful

Formula: C₉H₁₂N₂O₅

Purezza: 98+%

Colore e forma: Crystals or powder or crystalline powder, White to pale cream

Peso molecolare: 228.20

Ref: 02-A16026

1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione

CAS: 951-78-0

Formula: C₉H₁₂N₂O₅

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 228.2020

Ref: IN-DA005T5P

2'-Deoxyuridine

CAS: 951-78-0

2'-Deoxyuridine (2-deoxyuridine).

Formula: C₉H₁₂N₂O₅

Purezza: 98.51% - 99.88%

Colore e forma: Solid

Peso molecolare: 228.2

Ref: TM-T1721

2'-Deoxyuridine

CAS: 951-78-0

2'-Deoxyuridine

Purezza: ≥98%

Peso molecolare: 228.2g/mol

Ref: 54-BUP15860

2'-Deoxyuridine

CAS: 951-78-0

2'-Deoxyuridine

Formula: C₉H₁₂N₂O₅

Purezza: ≥95%

Colore e forma: white crystalline powder

Peso molecolare: 228.20g/mol

Ref: 54-OR0326

2'-Deoxyuridine-2-13C;1,3-15N

CAS: 369656-76-8, 951-78-0

Purezza: 99 atom % 13C; 99 atom % 15N

Colore e forma: White Solid

Peso molecolare: 231.23

Ref: 3U-M5445

2'-Desoxyuridine

CAS: 951-78-0

Formula: C₉H₁₂N₂O₅

Purezza: 95%~99%

Peso molecolare: 228.204

Ref: BP-BP4234

2''-Deoxyuridine

CAS: 951-78-0

Formula: C₉H₁₂N₂O₅

Purezza: ≥ 99.0%

Colore e forma: White to off-white crystalline powder

Peso molecolare: 228.21

Ref: 7W-GE3235

2’-Deoxyuridine

CAS: 951-78-0

Applications An uridine derivative as therapeutic agent for treating allergy, cancer, infection and autoimmune disease.
References Fu, M., et al.: J. Biol. Chem., 271, 9982 (1996), Thornalley, P., et al.: Biochem. J., et al.: 344, 109 (1999), Munter, T., et al.: Chem. Res. Toxicol., 15, 1549 (2002)

Formula: C₉H₁₂N₂O₅

Colore e forma: Neat

Peso molecolare: 228.20

Ref: TR-D288010

2'-Deoxyuridine

CAS: 951-78-0

2'-Deoxyuridine (2'-dU) is an intermediate in the synthesis of thymidylate, which is a precursor for DNA synthesis. It can be prepared through high-performance liquid chromatography. 2'-dU has been shown to inhibit the enzymatic activity of enzymes responsible for synthesizing uridine and thymidylate, leading to neuronal death. 2'-dU has also been shown to have a protective effect against mitochondrial dysfunction induced by hydrogen fluoride. It is also known to bind with toll-like receptor 4 (TLR4), which is involved in inflammatory responses. 2'-dU has been used as a fluorescence probe for nucleic acids and as a polymerase chain reaction (PCR) substrate.

Formula: C₉H₁₂N₂O₅

Purezza: Min. 98 Area-%

Colore e forma: White Powder

Peso molecolare: 228.21 g/mol

Ref: 3D-ND06282

1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione

CAS: 951-78-0

Formula: C₉H₁₂N₂O₅

Purezza: 97%

Colore e forma: Solid, Crystalline Powder

Peso molecolare: 228.204

Ref: 10-F093489

2’-Deoxyuridine extrapure, 98%

CAS: 951-78-0

Formula: C₉H₁₂N₂O₅

Peso molecolare: 228.20

Ref: SR-92627

2'-Deoxyuridine

CAS: 951-78-0

Please enquire for more information about 2'-Deoxyuridine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Formula: C₉H₁₂N₂O₅

Purezza: Min. 98 Area-%

Peso molecolare: 228.2 g/mol

Ref: 3D-Q-200273

Trifluridine EP Impurity D

CAS: 951-78-0

Formula: C₉H₁₂N₂O₅

Peso molecolare: 228.2

Ref: ST-EA-CP-T185004