CAS 957-68-6

Acido 7-amminocefalosporanico

Descrizione:

Acido 7-amminocefalosporanico (7-ACA) è un intermediario cruciale nella sintesi di antibiotici cefalosporinici, ampiamente utilizzati per trattare infezioni batteriche. È un composto biciclico che presenta un anello beta-lattamico, caratteristico degli antibiotici beta-lattamici, essenziale per la sua attività antibatterica. La struttura molecolare del 7-ACA include un gruppo amminico nella posizione 7, che ne aumenta la reattività e consente ulteriori modifiche chimiche per creare vari derivati della cefalosporina. Questo composto è tipicamente una polvere cristallina bianca o bianco sporco, solubile in acqua e solventi organici polari, e mostra stabilità in condizioni acide, ma può essere idrolizzato in ambienti alcalini. Il suo meccanismo antibatterico implica l'inibizione della sintesi della parete cellulare batterica, rendendolo efficace contro un ampio spettro di batteri Gram-positivi e alcuni Gram-negativi. A causa della sua importanza nelle applicazioni farmaceutiche, il 7-ACA è un elemento chiave nello sviluppo di nuovi antibiotici, contribuendo agli sforzi in corso per combattere la resistenza agli antibiotici.

Formula: C₁₀H₁₂N₂O₅S

InChI: InChI=1S/C10H12N2O5S/c1-4(13)17-2-5-3-18-9-6(11)8(14)12(9)7(5)10(15)16/h6,9H,2-3,11H2,1H3,(H,15,16)/t6-,9-/m1/s1

InChI key: InChIKey=HSHGZXNAXBPPDL-HZGVNTEJSA-N

SMILES: C(O)(=O)C=1N2[C@@]([C@H](N)C2=O)(SCC1COC(C)=O)[H]

Sinonimi:

• (6R,7R)-3-[(acetyloxy)methyl]-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• (6R-trans)-3-[(Acetyloxy)methyl]-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• (7R)-7-Aminocephalosporanic acid
• 3-(Acetoxymethyl)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• 3-(Acetoxymethyl)-7-aminocephem-4-carboxylic acid
• 3-Acetoxymethyl-7-aminoceph-3-em-4-carboxylic acid
• 3-Acetoxymethyl-7β-aminoceph-3-em-4-carboxylic acid
• 3-Acetoxymethylen-7-Amino-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid
• 3-Acetoxymethylen-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-2-carbonsaure
• 3-[(Acetyloxy)Methyl]-7-Amino-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-7-amino-8-oxo-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-7-amino-8-oxo-, (6R,7R)-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-7-amino-8-oxo-, (6R-trans)-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-amino-3-(hydroxymethyl)-8-oxo-, acetate (ester)
• 7-Aca
• 7-Acs
• 7-Amino Cephalosporanic Acid
• 7-Amino-3-acetoxymethyl-3-cephem-4-carboxylic acid
• 7-Amino-3-acetoxymethyl-Δ-3-cephem-4-carboxylic acid
• 7-Amino-3-acetoxymethyl-Δ3-cephem-4-carboxylic acid
• 7-Amino-3-acetoxymethyl-Δ³-cephem-4-carboxylic acid
• 7β-Amino-3-acetoxymethylcephemcarboxylic acid
• 7β-Aminocephalosporanic acid
• Acide 3-Acetoxymethylene-7-Amino-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylique
• Acido 3-Acetoximetilen-7-Amino-8-Oxo-5-Tia-1-Azabiciclo[4.2.0]Oct-2-Eno-2-Carboxilico

7-Aminocephalosporanic acid

CAS: 957-68-6

7-Aminocephalosporanic acid (7-ACA) is used for synthesis of cephalosporin antibiotics and intermediates.

Formula: C₁₀H₁₂N₂O₅S

Purezza: 91.05%

Colore e forma: White Solid Powder

Peso molecolare: 272.28

Ref: TM-T0989

7-Aminocephalosporanic acid

CAS: 957-68-6

Formula: C₁₀H₁₂N₂O₅S

Purezza: 95%

Colore e forma: Solid

Peso molecolare: 272.2777

Ref: IN-DA003NCV

7-Aminocephalosporanic acid

CAS: 957-68-6

Formula: C₁₀H₁₂N₂O₅S

Purezza: (HPLC) ≥ 95.0%

Colore e forma: White to off-white or beige crystalline powder

Peso molecolare: 272.28

Ref: 7W-GA7821

7-Aminocephalosporanic acid

CAS: 957-68-6

7-Aminocephalosporanic acid

Purezza: ≥90%

Peso molecolare: 272.28g/mol

Ref: 54-BUP16723

Cefazolin EP Impurity H (Cefalotin EP Impurity C, Cefoperazone EP Impurity E, 7-Aminocephalosporanic Acid)

CAS: 957-68-6

Formula: C₁₀H₁₂N₂O₅S

Colore e forma: White To Off-White Solid

Peso molecolare: 272.28

Ref: 4Z-C-9619

7-Aminocephalosporanic acid

CAS: 957-68-6

7-Aminocephalosporanic acid

Purezza: 96.4% (hplc) (Typical Value in Batch COA)

Colore e forma: slightly off-white crystalline powder

Peso molecolare: 272.28g/mol

Ref: 54-BIA4007

7-Aminocephalosporanic Acid

CAS: 957-68-6

Formula: C₁₀H₁₂N₂O₅S

Purezza: >97.0%(T)(HPLC)

Colore e forma: White to Light yellow to Light orange powder to crystal

Peso molecolare: 272.28

Ref: 3B-A1266

7-Aminocephalosporanic acid

CAS: 957-68-6

Purezza: 95.0%

Colore e forma: Solid, Powder

Peso molecolare: 272.2799987792969

Ref: 10-F221586

(6R,7R)-3-[(Acetyloxy)methyl]-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid (7-ACA)

Prodotto controllato

CAS: 957-68-6

Formula: C₁₀H₁₂N₂O₅S

Colore e forma: Neat

Peso molecolare: 272.28

Ref: 86-MM0238.08

Cefazolin EP Impurity H

CAS: 957-68-6

Formula: C₁₀H₁₂N₂O₅S

Peso molecolare: 272.3

Ref: ST-EA-CP-C149022

7-Aminocephalosporanic Acid

Prodotto controllato

CAS: 957-68-6

Impurity Cefoperazone EP Impurity E
Stability Hygroscopic
Applications 7-Aminocephalosporanic Acid (Cefoperazone EP Impurity E) is the starting material for semi-synthetic cephalosporins. Obtained by mild acid hydrolysis of cephalosporin C.
References Matsuda, A., et al.: J. Bacteriol., 169, 5815 (1987), Aramori, I., et al.: J. Ferment. Bioeng., 72, 227 (1991), Park, S., et al.: J. Biosci. Bioeng., 94, 218 (2002), Takimoto, A., et al.: Appl. Microbiol. Biotechnol., 65, 263 (2004),

Formula: C₁₀H₁₂N₂O₅S

Colore e forma: White To Light Yellow

Peso molecolare: 272.28

Ref: TR-A603415

7-Aminocephalosporanic acid

CAS: 957-68-6

7-Aminocephalosporanic acid is a molecule that can be used for wastewater treatment. It is an antibiotic with a broad spectrum of activity against bacteria and fungi, as well as some viruses. 7-Aminocephalosporanic acid has been shown to have antimicrobial properties in the human serum and to bind to the α subunit of cephalosporin, which is involved in bacterial cell wall synthesis. This compound contains nitrogen atoms with high biological reactivity, which may be due to its ability to form disulfide bonds on protein surfaces.

Formula: C₁₀H₁₂N₂O₅S

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 272.28 g/mol

Ref: 3D-FA11814

7-Aminocephalosporanic acid, Antibiotic for Culture Media Use Only

CAS: 957-68-6

7-Aminocephalosporanic acid is a chemical compound that is used as a reactant in the production of other chemicals.

Formula: C₁₀H₁₂N₂O₅S

Peso molecolare: 272.28 g/mol

Ref: 3D-A-5300

Cefoperazone EP Impurity E

CAS: 957-68-6

Formula: C₁₀H₁₂N₂O₅S

Peso molecolare: 272.3

Ref: ST-EA-CP-C154005

Cefalotin EP Impurity C

CAS: 957-68-6

Formula: C₁₀H₁₂N₂O₅S

Peso molecolare: 272.27

Ref: ST-EA-CP-C166003

7-Aminocephalosporanic acid

CAS: 957-68-6

Formula: C₁₀H₁₂N₂O₅S

Peso molecolare: 272.27

Ref: ST-EA-CP-C91007