CAS 96426-21-0

glicina-arginina-glicina-acido aspartico-serina

Descrizione:

La sostanza chimica nota come "glicina-arginina-glicina-acido aspartico-serina," con il numero CAS 96426-21-0, è un peptide composto da quattro amminoacidi: glicina (Gly), arginina (Arg), acido aspartico (Asp) e serina (Ser). Questo peptide è notevole per il suo ruolo nei processi biologici, in particolare nell'adesione cellulare e nella segnalazione. La sequenza di amminoacidi contribuisce alle sue proprietà strutturali e funzionali, rendendolo rilevante in varie applicazioni biochimiche, incluso lo sviluppo di farmaci e l'ingegneria dei tessuti. glicina-arginina-glicina-acido aspartico-serina può interagire con recettori o proteine specifiche, influenzando il comportamento e le risposte cellulari. La sua dimensione relativamente piccola consente una facile sintesi e modifica, il che è vantaggioso in contesti di ricerca e terapeutici. Inoltre, la presenza di catene laterali cariche e polari negli amminoacidi può influenzare la solubilità e l'interazione con altre biomolecole. In generale, questo peptide funge da modello prezioso per studiare le interazioni e le funzioni dei peptidi nei sistemi biologici.

Formula: C₁₇H₃₀N₈O₉

InChI: InChI=1/C17H30N8O9/c18-5-11(27)23-8(2-1-3-21-17(19)20)14(31)22-6-12(28)24-9(4-13(29)30)15(32)25-10(7-26)16(33)34/h8-10,26H,1-7,18H2,(H,22,31)(H,23,27)(H,24,28)(H,25,32)(H,29,30)(H,33,34)(H4,19,20,21)/t8-,9-,10-/m0/s1

SMILES: C(C[C@@H](C(=NCC(=N[C@@H](CC(=O)O)C(=N[C@@H](CO)C(=O)O)O)O)O)N=C(CN)O)CNC(=N)N

Sinonimi:

• H-Gly-Arg-Gly-Asp-Ser-OH
• glycyl-N~5~-(diaminomethylidene)-L-ornithylglycyl-L-alpha-aspartyl-L-serine

H-Gly-Arg-Gly-Asp-Ser-OH

CAS: 96426-21-0

GRGDS, a fragment derived from the cell binding region of fibronectin. Inhibitor of thrombin-induced platelet aggregation.

Formula: C₁₇H₃₀N₈O₉

Purezza: 96.7%

Colore e forma: White Lyophilisate

Peso molecolare: 490.47

Ref: 01-4008998

Gly-Arg-Gly-Asp-Ser

CAS: 96426-21-0

Formula: C₁₇H₃₀N₈O₉

Purezza: 98%

Peso molecolare: 490.4683

Ref: IN-DA019FVU

Gly-Arg-Gly-Asp-Ser

CAS: 96426-21-0

Gly-Arg-Gly-Asp-Ser (GRGDS) GRGDS is a cell binding protein domain derived from the cell-binding region of fibronectin.

Formula: C₁₇H₃₀N₈O₉

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 490.47

Ref: TM-TP1459

Gly-Arg-Gly-Asp-Ser

CAS: 96426-21-0

Formula: C₁₇H₃₀N₈O₉

Peso molecolare: 490.47

Ref: 7W-GL3717

Fibronectin Active Fragment (GRGDS)

CAS: 96426-21-0

Fibronectin is an extracellular matrix protein that plays a critical role in cell adhesion, migration, and differentiation. Fibronectin subunits are composed of repeating units of three types of modules: type I, type II, and type III. The active fragment of fibronectin refers to a small peptide sequence within the type III modules of fibronectin that has been shown to have potent biological activity.
The fibronectin active fragment, also known as the cell-binding domain or RGD domain, is a short peptide sequence consisting of the amino acid sequence Arg-Gly-Asp (RGD). This peptide sequence interacts with cell surface receptors known as integrins, which are important for mediating cell adhesion, migration, and signaling.
The fibronectin active fragment has been extensively studied as a research tool to investigate the mechanisms of cell adhesion and migration. It has also been used in tissue engineering applications to promote cell attachment and proliferation on synthetic biomaterials.

Formula: C₁₇H₃₀N₈O₉CH₃COOHH₂O

Purezza: Min. 95%

Peso molecolare: 490.47 g/mol

Ref: 3D-PFA-4189

Fibronectin Active Fragment (GRGDS)

CAS: 96426-21-0

Fibronectin is an extracellular matrix protein that plays a critical role in cell adhesion, migration, and differentiation. Fibronectin subunits are composed of repeating units of three types of modules: type I, type II, and type III. The active fragment of fibronectin refers to a small peptide sequence within the type III modules of fibronectin that has been shown to have potent biological activity.
The fibronectin active fragment, also known as the cell-binding domain or RGD domain, is a short peptide sequence consisting of the amino acid sequence Arg-Gly-Asp (RGD). This peptide sequence interacts with cell surface receptors known as integrins, which are important for mediating cell adhesion, migration, and signaling.
The fibronectin active fragment has been extensively studied as a research tool to investigate the mechanisms of cell adhesion and migration. It has also been used in tissue engineering applications to promote cell attachment and proliferation on synthetic biomaterials. This product is available as a 0.5mg vial.

Formula: C₁₇H₃₀N₈O₉

Purezza: Min. 95%

Peso molecolare: 490.47 g/mol

Ref: 3D-PFA-4189-V

H-Gly-Arg-Gly-Asp-Ser-OH TFA salt

CAS: 96426-21-0

H-Gly-Arg-Gly-Asp-Ser-OH TFA salt is a synthetic peptide that is designed to bind to the nuclear factor kappa B (NFκB) and inhibit its activation. NFκB is a transcription factor that regulates gene expression in response to various stimuli, including proinflammatory cytokines, oxidants, and electrophilic compounds. H-Gly-Arg-Gly-Asp-Ser-OH TFA salt has been shown to inhibit NFκB activation in a model system. This molecule also inhibits axonal growth and pluripotent cells differentiation, which may be due to its suppression of the signal peptide. The rate constant for this drug has been measured using polymer compositions and biocompatible polymers.

Formula: C₁₇H₃₀N₈O₉(freebase)

Purezza: Min. 95%

Peso molecolare: 490.47 g/mol

Ref: 3D-FG108418