CAS 979-92-0

L-Omocisteina, S-(5'-desossiadenosin-5'-il)-

Descrizione:

L-Omocisteina, S-(5'-desossiadenosin-5'-il)-, noto anche con il suo numero CAS 979-92-0, è un derivato di aminoacido contenente zolfo che gioca un ruolo significativo in vari processi biochimici, in particolare nel metabolismo della omocisteina. Questo composto è caratterizzato dalla presenza di uno scheletro di omocisteina legato a un gruppo di 5'-deossiadenosina, che è cruciale per la sua attività biologica. È tipicamente coinvolto in reazioni di metilazione ed è un intermedio chiave nella via di transulfurazione, influenzando la sintesi della cisteina e di altre biomolecole importanti. Il composto è solubile in acqua ed exhibit caratteristiche polari a causa della presenza di gruppi funzionali amminici e carbossilici. La sua importanza biologica è sottolineata dal suo coinvolgimento nella salute cardiovascolare, poiché livelli elevati di omocisteina sono associati a un aumento del rischio di malattie cardiovascolari. Inoltre, i derivati della L-omocisteina sono studiati per i loro potenziali ruoli nella segnalazione cellulare e come biomarcatori per varie condizioni di salute.

Formula: C₁₄H₂₀N₆O₅S

InChI: InChI=1S/C14H20N6O5S/c15-6(14(23)24)1-2-26-3-7-9(21)10(22)13(25-7)20-5-19-8-11(16)17-4-18-12(8)20/h4-7,9-10,13,21-22H,1-3,15H2,(H,23,24)(H2,16,17,18)/t6-,7+,9+,10+,13+/m0/s1

InChI key: InChIKey=ZJUKTBDSGOFHSH-WFMPWKQPSA-N

SMILES: O[C@H]1[C@H](N2C=3C(N=C2)=C(N)N=CN3)O[C@H](CSCC[C@@H](C(O)=O)N)[C@H]1O

Sinonimi:

• (S)-5'-(S)-(3-Amino-3-carboxypropyl)-5'-thioadenosin
• (S)-5'-(S)-(3-amino-3-carboxipropil)-5'-tioadenosina
• (S)-5'-(S)-(3-amino-3-carboxypropyl)-5'-thioadenosine
• <span class="text-smallcaps">L</span>-Homocysteine, S-(5′-deoxyadenosin-5′-yl)-
• <span class="text-smallcaps">L</span>-S-Adenosylhomocysteine
• Adenosine, 5'-S-(3-amino-3-carboxypropyl)-5'-thio-, L-
• Adenosine, 5′-S-(3-amino-3-carboxypropyl)-5′-thio-, <span class="text-smallcaps">L</span>-
• Adenosyl-<span class="text-smallcaps">L</span>-homocysteine
• Adenosyl-L-homocysteine
• Adenosylhomocysteine
• Homocysteine, S-adenosyl-, <span class="text-smallcaps">L</span>-
• Homocysteine, S-adenosyl-, L-
• L-S-Adenosylhomocysteine
• S-(5'-Adenosyl)-L-homocysteine
• S-(5′-Adenosyl)-<span class="text-smallcaps">L</span>-homocysteine
• S-(5′-Deoxyadenosin-5′-yl)-<span class="text-smallcaps">L</span>-homocysteine
• S-Adenosyl-<span class="text-smallcaps">L</span>-homocysteine
• S-Adenosyl-L-homocysteine
• S-Adenosylhomocysteine
• SAH (S-Adenosylhomocysteine)
• L-Homocysteine, S-(5′-deoxyadenosin-5′-yl)-
• S-(5′-Deoxyadenosin-5′-yl)-L-homocysteine
• (2S)-2-amino-4-({[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl}sulfanyl)butanoic acid (non-preferred name)
• 2-amino-4-({[5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl}sulfanyl)butanoic acid (non-preferred name)
• L-Homocysteine, S-(5'-deoxyadenosin-5'-yl)-
• 5'-Deoxy-s-adenosyl-L-homocysteine
• S-Adenosyl-L-homocystein
• AdenosylhoMocysteine-13C5
• S-(5'-Deoxyadenosin-5'-yl)-L-hoMocysteine-13C5
• 5μ-Deoxy-S-adenosyl-L-homocysteine, AdoHcy, S-(5μ-Deoxyadenosine-5μ)-L-homocysteine
• Adenosyl-L-hoMocysteine-13C5
• S-(5′
• (S)-2-amino-4-((((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)thio)butanoic acid
• S-Adenosyl-L-Homocysteine (50 mg)
• L-5'-S-(3-AMino-3-carboxypropyl)-
• (2S)-2-amino-4-[[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methylsulfanyl]butanoic acid
• ADOHCY
• S-(5'-DEOXYADENOSINE-5')-L-HOMOCYSTEINE
• L
• S-(5'-deoxyadenosin-5'-yl)
• -homocysteine
• 5'-thioadenosine-13C5
• L-S-AdenosylhoMocysteine-13C5
• -Adenosyl)-
• hpce
• S-(5′-Adenosyl)-L-homocysteine,5′-Deoxy-S-adenosyl-L-homocysteine, AdoHcy, S-(5′-Deoxyadenosine-5′)-L-homocysteine
• S-ADENOSYL-L-HOMOCYSTEINE (ADENOSINE-13C10, 98%)
• ( 35 ) -5-( 3-AMINO.-3 CARBOXYPROPYL) THIO ) -5-DEOXYADENOSINE
• 5'-DEOXY-S-ADENOSYL-
• S-(5'-Deoxyadenosine)-L-homocysteine
• S-(5'-Adenosyl)-L-homocysteine dihydrate
• S-(5'-Adenosyl)-L-homocysteine;AdoHcy;S-(5'-Deoxyadenosine)-L-homocysteine
• 5'-DEOXY-S-ADENOSYL-L-HOMOCYSTEINE USP/EP/BP
• HOMOCYSTEINE, S-ADENOSYL
• 5'-thioadenosine
• Ademetionine 1,4-Butanedisulfonate Impurity 1

S-Adenosyl-L-Homocysteine

CAS: 979-92-0

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

Formula: C₁₄H₂₀N₆O₅S

Colore e forma: White Crystalline Powder

Peso molecolare: 384.12159

Ref: 45-1012112

S-Adenosyl-L-homocysteine

CAS: 979-92-0

Formula: C₁₄H₂₀N₆O₅S

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 384.4108

Ref: IN-DA006AE7

S-Adenosyl-L-Homocysteine

CAS: 979-92-0

Formula: C₁₄H₂₀N₆O₅S

Peso molecolare: 384.41

Ref: 4Z-C-7727

S-Adenosylhomocysteine

CAS: 979-92-0

S-Adenosylhomocysteine

Purezza: 98%

Peso molecolare: 384.41g/mol

Ref: 54-OR1014905

S-(5''-Adenosyl)-L-homocysteine

CAS: 979-92-0

Formula: C₁₄H₂₀N₆O₅S

Purezza: (HPLC) ≥ 98.0%

Colore e forma: White to almost white powder

Peso molecolare: 384.41

Ref: 7W-GN9993

SAH

CAS: 979-92-0

SAH

Purezza: ≥98%

Peso molecolare: 384.41g/mol

Ref: 54-BUP06704

SAH

CAS: 979-92-0

SAH (SAH (S-Adenosylhomocysteine)) is an inhibitor for the METTL3-METTL14 heterodimer complex (METTL3-14, IC50: 0.9 μM).

Formula: C₁₄H₂₀N₆O₅S

Purezza: 98.45% - >99.99%

Colore e forma: Solid

Peso molecolare: 384.41

Ref: TM-TQ0208

S-Adenosyl-L-Homocysteine-15N4

CAS: 979-92-0

Formula: C₁₄H₂₀N₂₁₅N₄O₅S

Peso molecolare: 388.38

Ref: 4Z-C-7728

S-(5'-Adenosyl)-L-homocysteine-d4

Prodotto controllato

CAS: 979-92-0

Applications S-(5'-Adenosyl)-L-homocysteine-d4 is labelled S-(5'-Adenosyl)-L-homocysteine (A291500), a novel biomarker for predicting susceptibility of a subject to a mental or neurodegenerative disorder.
References Chamberlin, M., et al.: J. Clin. Invest., 98, 1021 (1996); Zoccolella, S., et al.: Neurology, 70, 222 (2008)

Formula: C₁₄D₄H₁₆N₆O₅S

Colore e forma: Neat

Peso molecolare: 388.44

Ref: TR-A291501

S-Adenosyl-L-Homocysteine

CAS: 979-92-0

Formula: C₁₄H₂₀N₆O₅S

Peso molecolare: 384.41

Ref: ST-EA-CP-A88015

S-(5'-Adenosyl)-L-homocysteine dihydrate

CAS: 979-92-0

S-(5'-Adenosyl)-L-homocysteine dihydrate is the active form of homocysteine. It has been shown to inhibit the growth of HL-60 cells and induce apoptosis in these cells. S-(5'-Adenosyl)-L-homocysteine dihydrate binds to dsDNA as a methyltransferase inhibitor, which leads to DNA methylation and inhibits DNA binding. The inhibition of DNA binding prevents transcription, leading to cell death. This drug has also been shown to have an anti-atherosclerotic effect in a model system by inhibiting the adenosine receptor.

Formula: C₁₄H₂₀N₆O₅S•(H₂O)₂

Purezza: Min. 98 Area-%

Colore e forma: Powder

Peso molecolare: 420.44 g/mol

Ref: 3D-NA17223

S-(5′-deoxyadenosin-5′-yl)-L-Homocysteine

CAS: 979-92-0

Formula: C₁₄H₂₀N₆O₅S

Purezza: 97%

Peso molecolare: 384.41

Ref: 10-F448169

S-(((2S,3S,4R,5R)-5-(6-Amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl-2,3,4,5-13C4)methyl-13C)-L-homocysteine

CAS: 979-92-0

Formula: C₉₁₃C₅H₂₀N₆O₅S

Colore e forma: Neat

Peso molecolare: 389.37

Ref: TR-A291502

S-(5-Adenosyl)-L-Homocysteine extrapure, 99%

CAS: 979-92-0

Formula: C₁₄H₂₀N₆O₅S

Purezza: min.99%

Colore e forma: White, Crystalline powder

Peso molecolare: 384.41

Ref: SR-46600

S-(5'-Adenosyl)-L-homocysteine

CAS: 979-92-0

Formula: C₁₄H₂₀N₆O₅S

Colore e forma: Neat

Peso molecolare: 384.41

Ref: TR-A291500

S-(((2S,3S,4R,5R)-5-(6-Amino-9H-purin-9-yl-13C5)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)-L-homocysteine

Prodotto controllato

CAS: 979-92-0

Formula: C₉₁₃C₅H₂₀N₆O₅S

Colore e forma: Neat

Peso molecolare: 389.37

Ref: TR-A291504

S-(((2S,3S,4R,5R)-5-(6-Amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl-13C)-L-homocysteine-13C4

Prodotto controllato

CAS: 979-92-0

Formula: C₉₁₃C₅H₂₀N₆O₅S

Colore e forma: Neat

Peso molecolare: 389.37

Ref: TR-A291507