CAS 99614-01-4

Cloridrato di ondansetron

Descrizione:

Cloridrato di ondansetron è un antagonista selettivo del recettore della serotonina 5-HT3 utilizzato principalmente come antiemetico per prevenire nausea e vomito causati da chemioterapia, radioterapia e chirurgia. È una polvere cristallina bianca o bianco sporco solubile in acqua e ha una formula molecolare che riflette la sua struttura complessa. La sostanza mostra un'alta affinità per i recettori 5-HT3, bloccando l'azione della serotonina, responsabile dell'insorgenza di nausea e vomito. Cloridrato di ondansetron viene tipicamente somministrato per via orale o endovenosa, e la sua farmacocinetica include un rapido assorbimento e una vita media relativamente breve, richiedendo più dosi in alcuni regimi di trattamento. Il composto è generalmente ben tollerato, con effetti collaterali comuni che includono mal di testa, costipazione e vertigini. È importante notare che, sebbene efficace, l'ondansetron deve essere usato con cautela in pazienti con determinate condizioni mediche e il suo uso durante la gravidanza deve essere valutato attentamente. In generale, Cloridrato di ondansetron è un farmaco critico nella gestione della nausea e del vomito indotti da chemioterapia, contribuendo in modo significativo al comfort del paziente e alla qualità della vita durante il trattamento del cancro.

Formula: C₁₈H₁₉N₃O·ClH

InChI: InChI=1S/C18H19N3O.ClH/c1-12-19-9-10-21(12)11-13-7-8-16-17(18(13)22)14-5-3-4-6-15(14)20(16)2;/h3-6,9-10,13H,7-8,11H2,1-2H3;1H

InChI key: InChIKey=MKBLHFILKIKSQM-UHFFFAOYSA-N

SMILES: O=C1C=2C=3C(N(C)C2CCC1CN4C(C)=NC=C4)=CC=CC3.Cl

Sinonimi:

• (+-)-2,3-Dihydro-9-Methyl-3-((2-Methylimidazol-1-Yl)Methyl)Carbazol-4(1H)-One Monohydrochloride Dihydrate
• 1,2,3,4-Tetrahydro-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-9H-carbazol-4-one hydrochloride
• 1,2,3,9-Tetrahydro-9-Methyl-3-[(2-Methyl-1H-Imidazol-1-Yl)Methyl]-4H-Carbazol-4-One Hydrochloride Dihydrate
• 1-methyl-N-[(3-endo)-9-methyl-9-azabicyclo[3.3.1]non-3-yl]-1H-indazole-3-carboxamide hydrochloride (1:1)
• 4H-Carbazol-4-One, 1,2,3,9-Tetrahydro-9-Methyl-3-((2-Methyl-1H-Imidazol-1-Yl)Methyl)-, Monohydrochloride, (+-)-, Dihydrate
• 4H-Carbazol-4-one, 1,2,3,9-tetrahydro-9-methyl-3-((2-methyl-1H-imidazol-1-yl)methyl)-, monohydrochloride
• 4H-Carbazol-4-one, 1,2,3,9-tetrahydro-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-, hydrochloride (1:1)
• 9-Methyl-3-((2-methyl-1H-imidazol-1-yl)methyl)-4H-carbazol-4-one monohydrochloride
• 9-Methyl-3-[(2-Methylimidazol-1-Yl)Methyl]-2,3-Dihydro-1H-Carbazol-4-One Dihydrate Hydrochloride
• 9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-1,2,3,9-tetrahydro-4H-carbazol-4-one hydrochloride (1:1)
• 9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-1,2,3,9-tetrahydro-4H-carbazol-4-one hydrochloride dihydrate
• Carbazol-4-One Dihydrate
• Emeset
• Gr 38032F
• NSC 665799
• Odansetron Hydrochloride Dihydrate
• Ondansetron HCl
• Ondansetron Hcl Dihydrate
• Ondansetron Hydrochloride Hydrate
• Ondansetron hydrochloride
• Osetron
• Sn 307
• Zofran
• Zofran ODT
• Zophren

Ondansetron Hydrochloride Dihydrate

CAS: 103639-04-9, 99614-01-4, 99614-02-5

Formula: C₁₈H₁₉N₃O·HCl·2H₂O

Purezza: >98.0%(T)(HPLC)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 365.86

Ref: 3B-O0407

Ondansetron hydrochloride

CAS: 99614-01-4

Ondansetron hydrochloride

Purezza: ≥98%

Peso molecolare: 329.82g/mol

Ref: 54-BUP11722

Ondansetron HCl

CAS: 99614-01-4

Formula: C₁₈H₁₉N₃O·HCl

Colore e forma: White To Off-White Solid

Peso molecolare: 293.37 36.46

Ref: 4Z-O-037

Ondansetron hydrochloride

CAS: 99614-01-4

Ondansetron hydrochloride (Zofran) is a serotonin 5-HT3 receptor antagonist, used to prevent nausea and vomiting caused by cancer chemotherapy, and radiation

Formula: C₁₈H₁₉N₃O·HCl

Purezza: 99.78%

Colore e forma: White Powder

Peso molecolare: 329.82

Ref: TM-T6616

Ondansetron Hydrocloride

CAS: 99614-01-4

Formula: C₁₈H₁₉N₃OHCl

Peso molecolare: 293.37 : 36.46

Ref: ST-EA-CP-O10010

Ondansetron hydrochloride - Bio-X ™

CAS: 99614-01-4

Ondansetron is a serotonin 5-HT3 receptor antagonist that has been shown to inhibit the effects of serotonin in the gastrointestinal tract, thereby preventing nausea and vomiting that is caused by cancer chemotherapy. Chemotherapy and radiotherapy are associated with the release of serotonin (5-HT) from enterochromaffin cells of the small intestine, initiating a vomiting reflex through stimulation of 5-HT3 receptors located on vagal afferents. Ondansetron blocks the initiation of this reflex. The drug binds to receptors on cells in the gastrointestinal tract that are normally activated by serotonin, thereby blocking its effect.

Formula: C₁₈H₂₀N₃OCl

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 329.82 g/mol

Ref: 3D-BO164177

Ondansetron HCl

CAS: 99614-01-4

Serotonin receptor 5-HT3 antagonist

Formula: C₁₈H₂₀N₃OCl

Purezza: Min. 95%

Colore e forma: White Powder

Peso molecolare: 329.82 g/mol

Ref: 3D-FO65112

Ondansetron Hydrochloride

Prodotto controllato

CAS: 99614-01-4

Formula: C₁₈H₁₉N₃O·HCl

Colore e forma: Neat

Peso molecolare: 329.80

Ref: TR-O655000