CAS 99755-59-6

Rotigotina

Descrizione:

Rotigotina è un agonista della dopamina sintetico utilizzato principalmente nel trattamento del morbo di Parkinson e della sindrome delle gambe senza riposo. Agisce stimolando i recettori della dopamina nel cervello, aiutando così ad alleviare i sintomi associati alla carenza di dopamina. La sostanza è caratterizzata dalla sua natura lipofila, che consente la somministrazione transdermica tramite una formulazione in cerotto, fornendo un rilascio costante del farmaco nel tempo. Rotigotina ha una emivita relativamente breve, richiedendo una somministrazione continua per mantenere livelli terapeutici. La sua struttura chimica include un centro chirale, che contribuisce alla sua attività farmacologica. Gli effetti collaterali comuni possono includere nausea, vertigini e sonnolenza, riflettendo la sua attività sul sistema nervoso centrale. Rotigotina è classificato nella categoria degli agonisti della dopamina non ergolinici, distinguendolo da altri trattamenti nella stessa classe. Come per qualsiasi farmaco, un attento monitoraggio è essenziale per gestire i potenziali effetti avversi e garantire risultati terapeutici ottimali.

Formula: C₁₉H₂₅NOS

InChI: InChI=1S/C19H25NOS/c1-2-11-20(12-10-17-6-4-13-22-17)16-8-9-18-15(14-16)5-3-7-19(18)21/h3-7,13,16,21H,2,8-12,14H2,1H3/t16-/m0/s1

InChI key: InChIKey=KFQYTPMOWPVWEJ-INIZCTEOSA-N

SMILES: OC1=C2C(C[C@@H](N(CCC3=CC=CS3)CCC)CC2)=CC=C1

Sinonimi:

• (-)-(S)-5,6,7,8-Tetrahydro-6-(propyl(2-(2-thienyl)ethyl)amino)-1-naphthol
• (-)-N 0437
• (6S)-5,6,7,8-Tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-1-naphthalenol
• (6S)-6-[Propyl(2-thiophen-2-ylethyl)amino]-5,6,7,8-tetrahydronaphthalen-1-ol
• (6S)-6-{propyl[2-(thiophen-2-yl)ethyl]amino}-5,6,7,8-tetrahydronaphthalen-1-ol
• (S)-(-)-5,6,7,8-Tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-1-naphthalenol
• (S)-(-)-Rotigotine
• (S)-5,6,7,8-Tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-naphth-1-ol
• (S)-6-[Propyl[2-(thiophen-2-yl)ethyl]amino]-5,6,7,8-tetrahydronaphthalen-1-ol
• 1-Naphthalenol 5,6,7,8-tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-, (6S)-
• 1-Naphthalenol, 5,6,7,8-tetrahydro-6-(propyl(2-(2-thienyl)ethyl)amino)-
• 1-Naphthalenol, 5,6,7,8-tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-, (S)-
• 2-(N-n-Propyl-N-2-thienylethylamino)-5-hydroxytetralin
• 5,6,7,8-Tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-1-naphthalenol
• 6-(Propyl(2-(2-thienyl)ethyl)amino)-5,6,7,8-tetrahydro-1-naphthalenol
• 6-{Propyl[2-(Thiophen-2-Yl)Ethyl]Amino}-5,6,7,8-Tetrahydronaphthalen-1-Ol
• Leganto
• N 0923
• Neupro

Rotigotine impurity standard

CAS: 99755-59-6

Rotigotine impurity standard

Colore e forma: White

Ref: 47-1243

Rotigotine

CAS: 99755-59-6

Rotigotine

Formula: C₁₉H₂₅NOS

Purezza: 99.6%

Colore e forma: White

Peso molecolare: 315.16569

Ref: 47-1242

ROTIGOTINE CRS

CAS: 99755-59-6

ROTIGOTINE CRS

Ref: 41-Y0002010

Rotigotine ((S)-6-{Propyl[2-(thiophen-2-yl)ethyl]amino}-5,6,7,8-tetrahydronaphthalen-1-ol)

CAS: 99755-59-6

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

Formula: C₁₉H₂₅NOS

Colore e forma: White Beige Powder

Peso molecolare: 315.16569

Ref: 45-1606060

(6S)-5,6,7,8-Tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-1-naphthalenol

CAS: 99755-59-6

Formula: C₁₉H₂₅NOS

Purezza: 99%

Colore e forma: Solid

Peso molecolare: 315.4729

Ref: IN-DA0039YJ

Rotigotine-

CAS: 99755-59-6

Rotigotine-

Purezza: ≥98%

Peso molecolare: 315.47g/mol

Ref: 54-BUP15521

Rotigotine

CAS: 99755-59-6

Rotigotine

Purezza: 99%

Peso molecolare: 315.47g/mol

Ref: 54-OR1023747

Rotigotine

CAS: 99755-59-6

Formula: C₁₉H₂₅NOS

Colore e forma: Neat

Peso molecolare: 315.47

Ref: 86-MM1403.00

Rotigotine-

CAS: 99755-59-6

Rotigotine (N-0923) is a non-ergot dopamine receptor agonist used in the therapy of Parkinson disease and restless leg syndrome.

Formula: C₁₉H₂₅NOS

Purezza: 98.08% - 99.59%

Colore e forma: Solid

Peso molecolare: 315.47

Ref: TM-T6647

(6S)-5,6,7,8-Tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-1-naphthalenol

Prodotto controllato

CAS: 99755-59-6

(6S)-5,6,7,8-Tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-1-naphthalenol is a potent and selective dopamine receptor agonist. It acts by binding to the dopamine receptors in the brain. This binding stimulates the release of dopamine and prevents it from being reabsorbed into the neurons, which in turn increases levels of extracellular dopamine in the synapse. (6S)-5,6,7,8-Tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-1-naphthalenol has been shown to have antidepressant effects in animal models of depression. It also has a long half life and can be administered as a transdermal patch for prolonged relief from depression symptoms.

Formula: C₁₉H₂₅NOS

Purezza: Min. 95%

Colore e forma: White Off-White Powder

Peso molecolare: 315.47 g/mol

Ref: 3D-FT76640

Rotigotine

CAS: 99755-59-6

Formula: C₁₉H₂₅NOS

Purezza: >98.0%(T)(HPLC)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 315.48

Ref: 3B-R0220

Rotigotine

CAS: 99755-59-6

Formula: C₁₉H₂₅NOS

Purezza: 99%

Peso molecolare: 315.166

Ref: 10-F513052

Rotigotine

CAS: 99755-59-6

Colore e forma: Neat

Ref: 61-FOR1403.00