Canale ionico
I canali ionici sono proteine specializzate che formano pori nelle membrane cellulari, consentendo il passaggio selettivo di ioni come sodio, potassio, calcio e cloruro. Questi canali svolgono un ruolo fondamentale in vari processi fisiologici, inclusa la trasmissione dell'impulso nervoso, la contrazione muscolare e la regolazione dell'omeostasi cellulare. I canali ionici sono obiettivi essenziali nella scoperta di farmaci, in particolare nel trattamento dei disturbi neurologici, delle malattie cardiovascolari e nella gestione del dolore. Presso CymitQuimica, offriamo una vasta gamma di proteine di canali ionici di alta qualità e reagenti correlati per supportare i tuoi progetti di ricerca e sviluppo di farmaci.
Trovati 106 prodotti per "Canale ionico".
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Aniracetam - Bio-X ™
CAS:Aniracetam is a nootropic drug that is used to alleviate memory disturbances caused by cerebrovascular disease and brain disorders. This drug has anti-depressive and anxiolytic properties and is said to target serotonin and dopamine receptors.
Formula:C12H13NO3Purezza:Min. 95%Colore e forma:PowderPeso molecolare:219.24 g/molOndansetron hydrochloride - Bio-X ™
CAS:Ondansetron is a serotonin 5-HT3 receptor antagonist that has been shown to inhibit the effects of serotonin in the gastrointestinal tract, thereby preventing nausea and vomiting that is caused by cancer chemotherapy. Chemotherapy and radiotherapy are associated with the release of serotonin (5-HT) from enterochromaffin cells of the small intestine, initiating a vomiting reflex through stimulation of 5-HT3 receptors located on vagal afferents. Ondansetron blocks the initiation of this reflex. The drug binds to receptors on cells in the gastrointestinal tract that are normally activated by serotonin, thereby blocking its effect.Formula:C18H20N3OClPurezza:Min. 95%Colore e forma:PowderPeso molecolare:329.82 g/molGlimepiride - Bio-X ™
CAS:Glimepiride is a sulfonylurea drug that is used in the treatment of type 2 diabetes mellitus. This drug works by inhibiting ATP-sensitive potassium channels by binding non-specifically to the B sites of both sulfonylurea receptor-1 (SUR1) and sulfonylurea receptor-2A (SUR2A) subunits. As a result, this promotes insulin secretion from beta cells.
Formula:C24H34N4O5SPurezza:Min. 95%Colore e forma:PowderPeso molecolare:490.62 g/molPicrotoxin - Bio-X ™
CAS:Picrotoxin is a GABA-A receptor antagonist that is used to relieve respiratory distress. This drug also is used as an antidote from poisoning by CNS depressants. Picrotoxin works by blocking the GABA activated chloride ionophore.Formula:C15H18O7·C15H16O6Purezza:Min. 95%Colore e forma:PowderPeso molecolare:602.58 g/molVincamine
CAS:Peripheral vasodilator; nootropic agentFormula:C21H26N2O3Purezza:Min. 95%Colore e forma:White PowderPeso molecolare:354.44 g/molVecuronium bromide
CAS:Antagonist of nicotinic acetylcholine receptors; nondepolarising muscle relaxant
Formula:C34H57BrN2O4Purezza:Min. 95%Peso molecolare:637.73 g/molOndansetron HCl dihydrate - Bio-X ™
CAS:Ondansetron is a serotonin 5-HT3 receptor antagonist that is used to prevent vomiting and nausea in patients undergoing chemotherapy. This drug blocks the initiation of the vomiting reflex.Formula:C18H19N3O•HCl•(H2O)2Purezza:Min. 95%Colore e forma:PowderPeso molecolare:365.85 g/molNicardipine HCl - Bio-X ™
CAS:Nicardipine is calcium channel blocker drug that is used for the treatment of hypertension and angina. This drug can also be used in the treatment of asthma and is said to enhance the action of various antineoplastic agents.Formula:C26H29N3O6•HClPurezza:Min. 95%Colore e forma:PowderPeso molecolare:515.99 g/molSenicapoc
CAS:Gardos channel inhibitorFormula:C20H15F2NOPurezza:Min. 95%Colore e forma:PowderPeso molecolare:323.34 g/molVerapamil HCl - Bio-X ™
CAS:Verapamil is drug that belongs to the class of drugs known as calcium channel blockers. It is used to treat high blood pressure, angina and other cardiovascular disorders. It works by relaxing the blood vessels so that blood can flow more easily. It does this by inhibiting the calcium ion influx through slow channels into conductile, contractile myocardial cells and vascular smooth muscle cells.Formula:C27H38N2O4•HClPurezza:Min. 95%Colore e forma:PowderPeso molecolare:491.06 g/molLercanidipine HCl - Bio-X ™
CAS:Lercanidipine is a calcium channel blocker that is used for the treatment of hypertension. This drug inhibits ion channels and interferes with the release of calcium from the sarcoplasmic reticulum. As a result, coronary and systemic arteries are dilated, allowing for an increased supply of oxygen to myocardial tissue. .Formula:C36H41N3O6•HClPurezza:Min. 95%Colore e forma:PowderPeso molecolare:648.19 g/molFlunarizine dihydrochloride - Bio-X ™
CAS:Flunarizine is calcium channel blocker that helps to reduce muscle spasms. It shows antimigraine and anticonvulsive activity. This occurs by inhibiting the influx of extracellular calcium through myocardial and vascular membrane pores by physically inhibiting the voltage-dependent calcium channels. Additionally, this drug is a D2 dopamine receptor antagonist.Formula:C26H26F2N2•(HCl)2Purezza:Min. 95%Colore e forma:PowderPeso molecolare:477.42 g/molTocainide HCl - Bio-X ™
CAS:Tocainide is a class 1b antiarrhythmic agent that is used in the treatment of ventricular arrhythmias. This drug acts on sodium channels to decrease the excitability of myocardial cells. This drug also prevents the depolarization of cardiac muscle cells and prolongs their refractory period.Formula:C11H17ClN2OPurezza:Min. 95%Colore e forma:PowderPeso molecolare:228.72 g/molMibefradil hydrochloride
CAS:Mibefradil is a calcium channel antagonist with the highest selectivity for T- and L-type channels, but also effective for N-, Q-, and R-type calcium channels at micromolar range. It decreases smooth muscle proliferation in response to vascular injury and causes vessel dilatation.Formula:C29H38FN3O3·2HClPurezza:Min. 95%Colore e forma:PowderPeso molecolare:568.55 g/molFG 7142
CAS:Partial inverse agonist of benzodiazepine sites of the GABAA receptors with anxiogenic properties. FG 7142 is a pharmacological stressor which generates anxiety in humans and in experimental animals such as rhesus monkeys and rodents. FG 7142 also reduces food intake and frequency of feeding in male and female rats.Formula:C13H11N3OPurezza:Min. 95%Colore e forma:Yellow PowderPeso molecolare:225.25 g/molLacidipine - Bio-X ™
CAS:Lacidipine is a lipophilic dihydropyridine calcium channel blocker that is used in the treatment of hypertension. This drug acts as an antihypertensive agent to dilate peripheral arteries and reduces blood pressure. Lacidipine blocks voltage-dependent L-type calcium channels.Formula:C26H33NO6Purezza:Min. 95%Colore e forma:PowderPeso molecolare:455.54 g/molLarixol
CAS:Inhibitor of TRPC6 cation channelFormula:C20H34O2Purezza:Min. 95%Colore e forma:PowderPeso molecolare:306.48 g/mol(+)-MK 801 maleate
CAS:NMDA glutamate receptor antagonistFormula:C16H15N·C4H4O4Purezza:Min. 98 Area-%Colore e forma:PowderPeso molecolare:337.37 g/molNisoldipine - Bio-X ™
CAS:Nisoldipine is a calcium channel blocker that is used to treat hypertension. It acts on vascular smooth muscle cells by blocking voltage-gated L-type calcium channels. By inhibiting the influx of calcium in smooth muscle cells, Nisoldipine prevents calcium-dependent smooth muscle contraction and subsequent vasoconstriction.Formula:C20H24N2O6Purezza:Min. 95%Colore e forma:PowderPeso molecolare:388.41 g/molAZD 9056 hydrochloride
CAS:A selective P2X7 receptor antagonist with an IC50 value of 11.2 nM. Prevents breast cancer resistance protein (BCRP)-mediated transport of methotrexate. Has therapeutic potential for osteoarthritis due to its anti-proliferative and pain-relieving effects.Formula:C24H35ClN2O2·HClPurezza:Min. 95%Colore e forma:White To Off-White SolidPeso molecolare:455.46 g/mol
