EGFR
Gli inibitori del recettore del fattore di crescita epidermico (EGFR) sono composti che bloccano la segnalazione dell'EGFR, un recettore spesso sovraespresso in vari tipi di cancro e che svolge un ruolo cruciale nell'angiogenesi. Gli inibitori dell'EGFR sono utilizzati per prevenire la crescita tumorale e le metastasi interrompendo le vie che promuovono la formazione di vasi sanguigni nei tumori. Questi inibitori sono ampiamente utilizzati nella ricerca e nella terapia del cancro. Presso CymitQuimica, offriamo una vasta selezione di inibitori dell'EGFR di alta qualità per supportare la tua ricerca in oncologia e angiogenesi.
Trovati 591 prodotti di "EGFR"
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PD153035 hydrochloride
CAS:<p>PD153035 hydrochloride (ZM 252868) is a effective and selective inhibitor of EGFR; few influence against FGFR, PGDFR, InsR, CSF-1, and Src.</p>Formula:C16H15BrClN3O2Purezza:99.39% - ≥95%Colore e forma:SolidPeso molecolare:396.67EAI045
CAS:EAI045, an allosteric inhibitor, targets towards drug-resistant EGFR mutants but avoids the wild-type receptor.Formula:C19H14FN3O3SPurezza:98.00% - 99.12%Colore e forma:SolidPeso molecolare:383.4AZ7550
CAS:AZ7550, an active metabolite of AZD9291, inhibits the activity of IGF1R (IC50: 1.6 μM).Formula:C27H31N7O2Purezza:97.07% - 99.75%Colore e forma:SolidPeso molecolare:485.58Epidermal Growth Factor
CAS:EGF binds EGFR, promotes cell growth & heals diabetic foot ulcers.Formula:C270H401N73O83S7Purezza:97.17%Colore e forma:SolidPeso molecolare:6222CP-380736
CAS:CP-380736 (PF-00520893) inhibits EGFR, a kinase key in cancer-signaling pathways like MAPK, JNK, and Akt.Formula:C14H18N2O5Purezza:99.68%Colore e forma:White To Off-White SolidPeso molecolare:294.3Tyrphostin 23
CAS:Tyrphostin 23 (AG18) inhibits EGFR with IC50 of 35 μM.Formula:C10H6N2O2Purezza:99.7% - 99.86%Colore e forma:Yellow-Tan SolidPeso molecolare:186.17EGFR-IN-12
CAS:EGFR-IN-12 (EGFR Inhibitor) is a cell permeable and selective inhibitor of EGFR kinase (IC50: 21 nM) and blocks receptor autophosphorylation in cells.Formula:C21H18F3N5OPurezza:98.3% - 99.76%Colore e forma:SolidPeso molecolare:413.4Ref: TM-T5168
1mg82,00€5mg159,00€10mg259,00€25mg520,00€50mg740,00€100mg1.008,00€500mg2.015,00€1mL*10mM (DMSO)168,00€Zorifertinib
CAS:Zorifertinib (AZD3759) is an orally active, effective and central nervous system-penetrant EGFR inhibitor.Formula:C22H23ClFN5O3Purezza:98.20% - 99.36%Colore e forma:White To Off-White SolidPeso molecolare:459.9MTX-211
CAS:MTX-211, an inhibitor of EGFR and PI3K, is used for the therapy of cancer and other diseases.Formula:C20H14Cl2FN5O2SPurezza:97.6% - >99.99%Colore e forma:SolidPeso molecolare:478.33Ref: TM-T4296
1mg64,00€2mg95,00€5mg170,00€10mg274,00€25mg464,00€50mg640,00€100mg847,00€200mg1.159,00€1mL*10mM (DMSO)180,00€AG 555
CAS:AG 555 (Tyrphostin B46) is an EGFR tyrosine kinase inhibitor.Formula:C19H18N2O3Purezza:98.02% - 99.94%Colore e forma:SolidPeso molecolare:322.36WHI-P258
CAS:WHI-P258, a weak JAK3 inhibitor, is used as a negative control in drug development.Formula:C16H15N3O2Purezza:99.66% - 99.92%Colore e forma:SolidPeso molecolare:281.31AG-1478
CAS:<p>AG-1478 (NSC-693255) (Tyrphostin AG-1478) is a selective EGFR inhibitor.</p>Formula:C16H14ClN3O2Purezza:99.03% - 99.71%Colore e forma:SolidPeso molecolare:315.75Tesevatinib
CAS:Tesevatinib (XL-647) is an oral, multi-targeted tyrosine kinase inhibitor.Cost-effective and quality-assured.Formula:C24H25Cl2FN4O2Purezza:97.89% - 98.66%Colore e forma:SolidPeso molecolare:491.39Ref: TM-TQ0166
1mg107,00€2mg156,00€5mg236,00€10mg457,00€25mg750,00€50mg1.026,00€1mL*10mM (DMSO)255,00€EBE-A22
CAS:EBE-A22 (PD153035 Analog 63) is a derivative of PD 153035 which can inhibit ErbB-1-phosphorylation, whereas EBE-A22 is inactive.Formula:C17H16BrN3O2Purezza:99.087% - 99.88%Colore e forma:SolidPeso molecolare:374.23Pelitinib
CAS:Pelitinib (EKB-569) (EKB-569) is an effective irreversible EGFR inhibitor (IC50: 38.5 nM).Formula:C24H23ClFN5O2Purezza:98.37% - 99.84%Colore e forma:Off-White SolidPeso molecolare:467.92WZ-3146
CAS:WZ3146: EGFR(L858R/E746_A750) inhibitor, IC50=2 nM, selective, doesn't block ERBB2(T798I).Formula:C24H25ClN6O2Purezza:97.15%Colore e forma:SolidPeso molecolare:464.95Ref: TM-T6733
1mg52,00€2mg74,00€5mg97,00€10mg180,00€25mg319,00€50mg510,00€100mg730,00€1mL*10mM (DMSO)106,00€CZC-8004
CAS:<p>CZC-8004 (CZC-00008004) is a pan-kinase(ABL kinase) inhibitor and binds a range of tyrosine kinases.</p>Formula:C17H16FN5Purezza:99.29%Colore e forma:SolidPeso molecolare:309.34CNX-2006
CAS:CNX-2006 is a novel irreversible mutant-selective EGFR inhibitor with IC50 of < 20 nM, with very weak inhibition at wild-type EGFR.Formula:C26H27F4N7O2Purezza:98.85% - 99.16%Colore e forma:SolidPeso molecolare:545.53Sapitinib
CAS:Sapitinib (AZD-8931) , a reversible, ATP competitive inhibitor of EGFR(IC50=4 nM), ErbB2(IC50=3 nM) and ErbB3(IC50=4 nM), is more effective over Gefitinib orFormula:C23H25ClFN5O3Purezza:98.89% - 99.83%Colore e forma:SolidPeso molecolare:473.93Olmutinib
CAS:Olmutinib is an oral mutant-specific EGFR inhibitor for cancer treatment with potential lower toxicity.Formula:C26H26N6O2SPurezza:99.14% - 99.63%Colore e forma:SolidPeso molecolare:486.59Ref: TM-T6918
2mg39,00€5mg57,00€10mg88,00€25mg137,00€50mg180,00€100mg283,00€200mg462,00€1mL*10mM (DMSO)59,00€
