EGFR
Gli inibitori del recettore del fattore di crescita epidermico (EGFR) sono composti che bloccano la segnalazione dell'EGFR, un recettore spesso sovraespresso in vari tipi di cancro e che svolge un ruolo cruciale nell'angiogenesi. Gli inibitori dell'EGFR sono utilizzati per prevenire la crescita tumorale e le metastasi interrompendo le vie che promuovono la formazione di vasi sanguigni nei tumori. Questi inibitori sono ampiamente utilizzati nella ricerca e nella terapia del cancro. Presso CymitQuimica, offriamo una vasta selezione di inibitori dell'EGFR di alta qualità per supportare la tua ricerca in oncologia e angiogenesi.
Trovati 589 prodotti di "EGFR"
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MTX-211
CAS:MTX-211, an inhibitor of EGFR and PI3K, is used for the therapy of cancer and other diseases.Formula:C20H14Cl2FN5O2SPurezza:97.6% - >99.99%Colore e forma:SolidPeso molecolare:478.33Ref: TM-T4296
1mg64,00€2mg95,00€5mg170,00€10mg274,00€25mg464,00€50mg640,00€100mg847,00€200mg1.159,00€1mL*10mM (DMSO)180,00€SU 4313
CAS:SU 4313 is a bioactive chemical.Formula:C18H17NOPurezza:99.51% - 99.89%Colore e forma:SolidPeso molecolare:263.33Ref: TM-T3568
1mg35,00€5mg70,00€10mg97,00€25mg170,00€50mg250,00€100mg373,00€200mg547,00€1mL*10mM (DMSO)78,00€EBE-A22
CAS:EBE-A22 (PD153035 Analog 63) is a derivative of PD 153035 which can inhibit ErbB-1-phosphorylation, whereas EBE-A22 is inactive.Formula:C17H16BrN3O2Purezza:99.087% - 99.88%Colore e forma:SolidPeso molecolare:374.23AG 555
CAS:AG 555 (Tyrphostin B46) is an EGFR tyrosine kinase inhibitor.Formula:C19H18N2O3Purezza:98.02% - 99.94%Colore e forma:SolidPeso molecolare:322.36WHI-P258
CAS:WHI-P258, a weak JAK3 inhibitor, is used as a negative control in drug development.Formula:C16H15N3O2Purezza:99.66% - 99.92%Colore e forma:SolidPeso molecolare:281.31Chrysophanol
CAS:Chrysophanol (Turkey Rhubarb) is an EGFR/mTOR pathway inhibitor, which can be found in rhubarb, and sorrel.Formula:C15H10O4Purezza:99.44% - 99.91%Colore e forma:Physical Description Golden Yellow Plates Or Brown Powder Melting Point 196°CPeso molecolare:254.24EGFR/ErbB-2/ErbB-4 inhibitor-2
CAS:EGFR/ErbB-2/ErbB-4 inhibitor-2 (EGFR/ErbB2 Inhibitor) is a cell-permeable inhibitor of EGFR and c-ErbB2 (IC50s = 20 and 79 nM, respectively)Formula:C23H21N3O3Purezza:99.55%Colore e forma:SolidPeso molecolare:387.43Ref: TM-T21954
1mg50,00€5mg94,00€10mg140,00€25mg245,00€50mg369,00€100mg537,00€200mg712,00€1mL*10mM (DMSO)103,00€WZ8040
CAS:WZ8040 is a novel mutant-selective irreversible EGFRT790M inhibitor, does not inhibit ERBB2 phosphorylation (T798I).
Formula:C24H25ClN6OSPurezza:97.42% - 99.785%Colore e forma:SolidPeso molecolare:481.01AEE788
CAS:AEE788 (NVP-AEE 788) has been used in trials studying the treatment of Cancer, Glioblastoma Multiforme, and Brain and Central Nervous System Tumors.Formula:C27H32N6Purezza:98% - >99.99%Colore e forma:SolidPeso molecolare:440.58Ref: TM-T2116
2mg47,00€5mg70,00€10mg103,00€25mg188,00€50mg325,00€100mg490,00€500mg1.103,00€1mL*10mM (DMSO)77,00€WHI-P180
CAS:WHI-P180 (Janex 3) is a potent EGFR and Cdk2 inhibitors with IC50 of 4.0 and 1.0 uM, respectively.Formula:C16H15N3O3Purezza:99.21%Colore e forma:SolidPeso molecolare:297.31NRC-2694 hydrochloride
CAS:NRC-2694 hydrochloride is an epidermal growth factor receptor (EGFR) antagonist potentially for the treatment of solid tumors.Formula:C24H27ClN4O3Colore e forma:SolidPeso molecolare:454.95Gefitinib hydrochloride
CAS:Obtustatin triacetate is an integrin derived from the venom of Vipera lebetina obtusa and is an α1β1 integrin and in vivo angiogenesis inhibitor.Formula:C22H25Cl2FN4O3Purezza:99.8%Colore e forma:SolidPeso molecolare:483.36Cavutilide
CAS:Cavutilide has antiarrhythmic activity, inhibits hERG K(+) channels, and can be used to study heart failure and persistent atrial fibrillation.Formula:C22H26FN3O3Purezza:99.82% - 99.85%Colore e forma:SolidPeso molecolare:399.458Canertinib dihydrochloride
CAS:Canertinib dihydrochloride (PD-183805 dihydrochloride) is the hydrochloride salt of an orally bio-available quinazoline with potential antineoplastic andFormula:C24H27Cl3FN5O3Purezza:99.13% - >99.99%Colore e forma:SolidPeso molecolare:558.86BMS-690514
CAS:BMS-690514 is a potent and orally active inhibitor of EGFR and VEGFR. It has IC50s of 5, 20 and 60 nM for EGFR, HER 2 and HER 4, respectively.Formula:C19H24N6O2Purezza:99.08%Colore e forma:SolidPeso molecolare:368.43Naquotinib mesylate
CAS:Naquotinib mesylate (ASP8273 (mesylate)) is an orally available, mutant-selective and irreversible inhibitor of EGFR(iC50s of 8-33 nM and 230 nM for toward EGFRFormula:C31H46N8O6SPurezza:98%Colore e forma:SolidPeso molecolare:658.81Almonertinib hydrochloride
CAS:Almonertinib hydrochloride (HS-10296 hydrochloride) is a small molecule inhibitor of EGFR-activating mutations and T790M-resistant mutation.Formula:C30H36ClN7O2Purezza:98.01% - 98.12%Colore e forma:SolidPeso molecolare:562.1Ref: TM-T5675
1mg92,00€5mg185,00€10mg311,00€25mg537,00€50mg753,00€100mg1.026,00€1mL*10mM (DMSO)240,00€EGFR T790M/L858R-IN-8
CAS:EGFRT790M/L858R-IN-8 (compound 9) is a potent inhibitor of EGFR, specifically targeting the EGFRT790M/L858R mutations with an IC50 of 56.8 μM. This compound does not show significant antiproliferative effects on cancer cell lines A549, A431, and NHI-H1975.Formula:C16H11BrN2O3Colore e forma:SolidPeso molecolare:359.17Runimotamab
Runimotamab, an IgG1-κ humanized chimeric antibody, targets CD3E and HER2 [1].Colore e forma:Odour LiquidFepixnebart
CAS:Fepixnebart is a humanized IgG4κ antibody that targets TGF-alpha (TGFA).Colore e forma:Liquid
