EGFR
Gli inibitori del recettore del fattore di crescita epidermico (EGFR) sono composti che bloccano la segnalazione dell'EGFR, un recettore spesso sovraespresso in vari tipi di cancro e che svolge un ruolo cruciale nell'angiogenesi. Gli inibitori dell'EGFR sono utilizzati per prevenire la crescita tumorale e le metastasi interrompendo le vie che promuovono la formazione di vasi sanguigni nei tumori. Questi inibitori sono ampiamente utilizzati nella ricerca e nella terapia del cancro. Presso CymitQuimica, offriamo una vasta selezione di inibitori dell'EGFR di alta qualità per supportare la tua ricerca in oncologia e angiogenesi.
Trovati 591 prodotti di "EGFR"
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Fidasimtamab
CAS:Fidasimtamab, a recombinant human IgG1 bispecific antibody, targets both HER2 and PD-1, bridging T cells and tumor cells to modulate immune responses.Purezza:95% - 98.0% (SDS-PAGE); 98.3% (SEC-HPLC)Colore e forma:LiquidFepixnebart
CAS:Fepixnebart is a humanized IgG4κ antibody that targets TGF-alpha (TGFA).Colore e forma:LiquidImgatuzumab
CAS:<p>Imgatuzumab (RG 7160) is a humanized anti-EGFR monoclonal antibody and immunomodulator for cancer research.</p>Colore e forma:LiquidPeso molecolare:145.0 (kDa)Anbenitamab
CAS:Anbenitamab (KN-026) is a bispecific HER2 antibody for metastatic breast cancer research, blocking HER2 pathways and mediating ADCC.Colore e forma:LiquidEGFR T790M/L858R-IN-8
CAS:EGFRT790M/L858R-IN-8 (compound 9) is a potent inhibitor of EGFR, specifically targeting the EGFRT790M/L858R mutations with an IC50 of 56.8 μM. This compound does not show significant antiproliferative effects on cancer cell lines A549, A431, and NHI-H1975.Formula:C16H11BrN2O3Colore e forma:SolidPeso molecolare:359.17Becotatug
CAS:Becotatug (JMT101) is a humanised monoclonal antibody targeting EGFR, antitumour when combined with Osimertinib for treating EGFR-mutated advanced NSCLC.Purezza:95% - 99.1% (SDS-PAGE); 98.1% (SEC-HPLC)Colore e forma:LiquidPeso molecolare:145.52 kDaRunimotamab
Runimotamab, an IgG1-κ humanized chimeric antibody, targets CD3E and HER2 [1].Colore e forma:Odour LiquidFutuximab
CAS:Futuximab is a chimeric monoclonal antibody targeting EGFR, commonly used in combination with zatuximab to form Sym004.Purezza:95% - 97.5% (SDS-PAGE); 96.3% (SEC-HPLC)Colore e forma:LiquidZalutumumab
CAS:Zalutumumab is a high-affinity fully human monoclonal antibody ,the extracellular domain of the EGFR squamous cell carcinoma of the head and neck (SCCHN).Purezza:95%Colore e forma:LiquidElgemtumab
CAS:Elgemtumab (LJM716) is a fully humanised monoclonal antibody targeting HER3/ERBB3, acting as an antagonist to block HER3/Akt phosphorylation antitumour.Purezza:95%Colore e forma:LiquidPeso molecolare:144.15 kDaDepatuxizumab
CAS:Depatuxizumab is a humanised monoclonal antibody targeting EGFR with blood-brain barrier (BBB) permeability, inhibit tumor growth,GBM,SCCHN.Purezza:95%Colore e forma:LiquidIzalontamab
CAS:Izalontamab (SI-B001) is a bispecific EGFR/HER3 monoclonal antibody that binds to both EGFR×EGFR homodimers and EGFR×HER3 heterodimers.Purezza:95%+ - 95.3% (SDS-PAGE); 99.2% (SEC-HPLC)Colore e forma:LiquidPonezumab
CAS:Ponezumab (PF-04360365), a humanized IgG2 antibody, lowers Aβ in the CNS & boosts mice memory. Used in Alzheimer's research.Colore e forma:Liquidlavendustin A
CAS:lavendustin A (RG-14355) is a potent, cell-permeable inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase.Formula:C21H19NO6Purezza:98%Colore e forma:Off-White SolidPeso molecolare:381.38IGF-1R modulator 1
CAS:<p>IGF-1Rmodulator 1 (Example 5) is an IGF-1R modulator featuring an EC50 of 0.29 μM (FGFR1), 0.25 μM (IGF1R), 0.34 μM (TrkA), and 0.39 μM (TrkB). This compound is useful in research on diseases characterized by impaired signaling of neurotrophic and/or other trophic factors, such as Alzheimer's disease.</p>Formula:C22H17N3O4Colore e forma:SolidPeso molecolare:387.39ZM323881 hydrochloride
CAS:ZM323881 hydrochloride (ZM 323881 HCl) is a potent and selective VEGFR2 inhibitor.Formula:C22H19ClFN3O2Purezza:99.43%Colore e forma:SolidPeso molecolare:411.86Ref: TM-T1991
1mg35,00€5mg70,00€10mg101,00€25mg236,00€50mg389,00€100mg582,00€200mg823,00€1mL*10mM (DMSO)72,00€Icotinib
CAS:Icotinib (Conmana) is an orally available quinazoline-based inhibitor of epidermal growth factor receptor (EGFR), with potential antineoplastic activity.Formula:C22H21N3O4Purezza:99.76% - 99.94%Colore e forma:SolidPeso molecolare:391.42Icotinib Hydrochloride
CAS:Icotinib Hydrochloride, an oral EGFR inhibitor (BPI-2009H), may halt cancer growth by blocking EGFR signaling.Formula:C22H22ClN3O4Purezza:99.89%Colore e forma:SolidPeso molecolare:427.88TAK-285
CAS:TAK-285 is a novel dual HER2 and EGFR(HER1) inhibitor, >10-fold selectivity for HER1/2 than HER4, less potent to MEK1/5, c-Met, Aurora B, Lck, CSK etc.Formula:C26H25ClF3N5O3Purezza:99.73%Colore e forma:SolidPeso molecolare:547.96Ref: TM-T6039
1mg38,00€5mg80,00€10mg120,00€25mg216,00€50mg354,00€100mg512,00€200mg727,00€1mL*10mM (DMSO)96,00€EGFR-IN-31
CAS:EGFR-IN-31: Potent EGFR inhibitor, targets mutations & overexpression in NSCLC; potential cancer research compound. (WO2021185298A1, 2)Formula:C32H36FN7O2Colore e forma:SolidPeso molecolare:569.67
