EGFR
Gli inibitori del recettore del fattore di crescita epidermico (EGFR) sono composti che bloccano la segnalazione dell'EGFR, un recettore spesso sovraespresso in vari tipi di cancro e che svolge un ruolo cruciale nell'angiogenesi. Gli inibitori dell'EGFR sono utilizzati per prevenire la crescita tumorale e le metastasi interrompendo le vie che promuovono la formazione di vasi sanguigni nei tumori. Questi inibitori sono ampiamente utilizzati nella ricerca e nella terapia del cancro. Presso CymitQuimica, offriamo una vasta selezione di inibitori dell'EGFR di alta qualità per supportare la tua ricerca in oncologia e angiogenesi.
Trovati 595 prodotti di "EGFR"
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AEE788
CAS:AEE788 (NVP-AEE 788) has been used in trials studying the treatment of Cancer, Glioblastoma Multiforme, and Brain and Central Nervous System Tumors.Formula:C27H32N6Purezza:98% - >99.99%Colore e forma:SolidPeso molecolare:440.58WHI-P180
CAS:WHI-P180 (Janex 3) is a potent EGFR and Cdk2 inhibitors with IC50 of 4.0 and 1.0 uM, respectively.Formula:C16H15N3O3Purezza:99.21%Colore e forma:SolidPeso molecolare:297.31NRC-2694 hydrochloride
CAS:NRC-2694 hydrochloride is an epidermal growth factor receptor (EGFR) antagonist potentially for the treatment of solid tumors.Formula:C24H27ClN4O3Colore e forma:SolidPeso molecolare:454.95Trastuzumab
CAS:Trastuzumab is a humanized monoclonal antibody for patients with invasive breast cancers that overexpress HER2.Purezza:97.1% (SDS-PAGE); 99.2% (SEC-HPLC) - SDS-PAGE: 97.1%；SEC-HPLC: 99.2%Colore e forma:LiquidPeso molecolare:Approximately 145.53 kDaSulforaphene
CAS:Sulforaphene, from radish seeds, aids cancer cell apoptosis and inhibits migration; has an ED50 for velvetleaf at ~2x10^-4 M.Formula:C6H9NOS2Purezza:97.55% - 99.67%Colore e forma:Slightly Yellowish LiquidPeso molecolare:175.27SU5204
CAS:SU5204 (3-[(2-Ethoxyphenyl)methylidene]-1H-indol-2-one), an analogue of SU5025, pharmacologically inhibits VEGFR2(IC50s of 4 and 51.5 μM for FLK-1 (VEGFR-2) andFormula:C17H15NO2Purezza:99.46%Colore e forma:SolidPeso molecolare:265.31PP2
CAS:PP2 (AG 1879,AGL 1879) is a effective inhibitor of Lck/Fyn (IC50:4/5 nM) , ~100-fold less potent to EGFR, inactive for ZAP-70, PKA and JAK2.Formula:C15H16ClN5Purezza:98% - 98.21%Colore e forma:White SolidPeso molecolare:301.77Tyrphostin AG30
CAS:Tyrphostin AG30 (AG30) (AG30) is a potent protein tyrosine kinases (PTK) inhibitor.Formula:C10H7NO4Purezza:99.02%Colore e forma:SolidPeso molecolare:205.17PD-161570
CAS:PD-161570 is a potent and ATP-competitive human FGF-1 receptor inhibitor with an IC50 of 39.9 nM and a Ki of 42 nM.Formula:C26H35Cl2N7OPurezza:99.92%Colore e forma:SolidPeso molecolare:532.51Lazertinib
CAS:Lazertinib (GNS-1480) is a potent, selective, irreversible EGFR-TKI; IC50: 1.7-76 nM for various EGFR mutations.Formula:C30H34N8O3Purezza:98.7% - 99.90%Colore e forma:SolidPeso molecolare:554.64Tyrphostin A1
CAS:Tyrphostin A1 (Tyrphostin 1) is an inhibitor of EGFR tyrosine kinase .Formula:C11H8N2OPurezza:98.32%Colore e forma:SolidPeso molecolare:184.19WZ4002
CAS:WZ4002 is a mutant-selective EGFR inhibitor for EGFR(L858R) and EGFR(T790M) with IC50 of 2 nM/8 nM.Formula:C25H27ClN6O3Purezza:97.51%Colore e forma:SolidPeso molecolare:494.97MAZ51
CAS:MAZ51 is a VEGFR-3 (Flt-4) tyrosine kinase inhibitor.Formula:C21H18N2OPurezza:98.53%Colore e forma:SolidPeso molecolare:314.38Gefitinib-based PROTAC 3
CAS:Gefitinib-PROTAC 3 degrades EGFR in cancer cells; DC50s: 11.7 nM (HCC827) and 22.3 nM (H3255).Formula:C47H57ClFN7O8SPurezza:97.29% - 98.25%Colore e forma:SolidPeso molecolare:934.51Dacomitinib hydrate
CAS:Dacomitinib hydrate (PF 299804) is a highly selective and second-generation small-molecule inhibitor of the pan-epidermal growth factor receptor family ofFormula:C24H27ClFN5O3Purezza:99.52%Colore e forma:SolidPeso molecolare:487.96Almonertinib
CAS:Almonertinib (HS-10296) is an inhibitor of EGFR activation mutation and tolerant mutation of EGFR T790M, which has only limited activity against wild-type EGFR.Formula:C30H35N7O2Purezza:99.99%Colore e forma:SolidPeso molecolare:525.64G5-7
CAS:G5-7 is an oral JAK2 inhibitor targeting EGFR/STAT3 phosphorylation with potential for glioma research.Formula:C22H19F2NO3Purezza:97.3%Colore e forma:SolidPeso molecolare:383.39AG-494
CAS:AG-494 (Tyrphostin B48) is an inhibitor of epidermal growth factor receptor kinase.Formula:C16H12N2O3Purezza:98.69%Colore e forma:SolidPeso molecolare:280.28Neratinib
CAS:Neratinib (HKI-272) (HKI-272) is an orally available, irreversible tyrosine kinase inhibitor for HER2 and EGFR (IC50: 59/92 nM), respectively.Formula:C30H29ClN6O3Purezza:96.17% - 99.85%Colore e forma:SolidPeso molecolare:557.04Osimertinib mesylate
CAS:<p>Osimertinib mesylate (AZD-9291 mesylate) is an EGFR third-generation inhibitor. Osimertinib mesylate has antitumor activity. Cost-effective and quality-assured.</p>Formula:C29H37N7O5SPurezza:99.46% - >99.99%Colore e forma:SolidPeso molecolare:595.71
