BTK
Gli inibitori della tirosina chinasi di Bruton (BTK) sono composti che mirano specificamente a inibire la BTK, un enzima cruciale coinvolto nella segnalazione del recettore delle cellule B e nella regolazione dell'angiogenesi. La BTK svolge un ruolo significativo nella proliferazione e nella sopravvivenza delle cellule cancerose, in particolare nelle malignità ematologiche. Inibendo la BTK, questi composti possono interrompere l'angiogenesi e la crescita tumorale, rendendoli preziosi nella terapia del cancro. Presso CymitQuimica, offriamo una gamma di inibitori della BTK di alta qualità per supportare la tua ricerca in oncologia, immunologia e angiogenesi.
Trovati 169 prodotti per "BTK".
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Fenebrutinib
CAS:Fenebrutinib (GDC-0853) is a selective and noncovalent Btk inhibitor (Ki: 0.91 nM).Formula:C37H44N8O4Purezza:98.26% - 98.94%Colore e forma:SolidPeso molecolare:664.8Ibrutinib
CAS:Ibrutinib (PCI-32765) is an irreversible inhibitor of BTK (IC50: 0.5 nM) that selectively blocks B cell activation.Formula:C25H24N6O2Purezza:98% - 99.95%Colore e forma:White SolidPeso molecolare:440.50Branebrutinib
CAS:Branebrutinib (BMS986195) is a potent, covalent inhibitor of Bruton's tyrosine kinase (BTK), >5,000-fold selective over all kinases outside of the Tec family.Formula:C20H23FN4O2Purezza:95.86% - 99.31%Colore e forma:SolidPeso molecolare:370.42(Z)-LFM-A13
CAS:(Z)-LFM-A13(IC50=2.5 μM), a specific Bruton's tyrosine kinase (BTK), is more than 100-fold specificity than other protein kinases, such as JAK1, JAK2, HCK, EGFR, and IRK.Formula:C11H8Br2N2O2Purezza:99.88%Colore e forma:SolidPeso molecolare:360BIIB068
CAS:BIIB068 is an selective, reversible and orally active BTK inhibitor (IC50 = 1 nM, Kd = 0.3 nM). BIIB068 is 400 times more selective for BTK than other kinases.Formula:C23H29N7O2Purezza:97.98%Colore e forma:White SolidPeso molecolare:435.52Ref: TM-T9192
1mg46,00€5mg90,00€1mL*10mM (DMSO)100,00€10mg152,00€25mg264,00€50mg398,00€100mg532,00€200mg705,00€Ibrutinib deacryloylpiperidine
CAS:Ibrutinib deacryloylpiperidine (IBT4A) is a highly selective Bruton’s tyrosine kinase (BTK) irreversible inhibitor with an IC50 of 0.5 nM.Formula:C17H13N5OPurezza:99.47%Colore e forma:SolidPeso molecolare:303.32Olmutinib
CAS:Olmutinib is an oral mutant-specific EGFR inhibitor for cancer treatment with potential lower toxicity.Formula:C26H26N6O2SPurezza:99.14% - 99.63%Colore e forma:SolidPeso molecolare:486.59Ref: TM-T6918
2mg37,00€5mg54,00€1mL*10mM (DMSO)56,00€10mg84,00€25mg130,00€50mg170,00€100mg268,00€200mg437,00€CNX-774
CAS:CNX-774 is a highly specific, irreversible, and orally active BTK inhibitor (IC50<1 nM).Formula:C26H22FN7O3Purezza:97.35% - 99.11%Colore e forma:SolidPeso molecolare:499.5Ref: TM-T2302
1mg38,00€2mg50,00€5mg84,00€1mL*10mM (DMSO)88,00€10mg119,00€25mg222,00€50mg369,00€100mg537,00€500mg1.161,00€PCI 29732
CAS:PCI 29732 is a selective and irreversible Btk inhibitor with IC50 of 8.2 nM in a FRET based biochemical enzymology assay.Formula:C22H21N5OPurezza:99.81%Colore e forma:SolidPeso molecolare:371.43ONO-4059 analog
CAS:ONO-4059 analog (ONO-WG-307)ue is an analogue of ONO-4059, which is a highly potent and selective oral BTK inhibitor with IC50 of 23.9 nM. Phase 1.Formula:C25H24N6O3Purezza:99.93%Colore e forma:SolidPeso molecolare:456.5Ref: TM-T6921
1mg43,00€2mg56,00€1mL*10mM (DMSO)90,00€5mg93,00€10mg137,00€25mg264,00€50mg439,00€100mg627,00€Spebrutinib
CAS:Spebrutinib (LMK-435) is an orally bioavailable, selective inhibitor of Bruton's agammaglobulinemia tyrosine kinase (BTK), with potential antineoplasticFormula:C22H22FN5O3Purezza:97.02% - >99.99%Colore e forma:SolidPeso molecolare:423.44N-piperidine Ibrutinib
CAS:N-piperidine Ibrutinib is a potent BTK inhibitor with IC50s of 51.0 for WT BTK and 30.7 nM for C481S BTK respectively.Formula:C22H22N6OPurezza:96.65%Colore e forma:SolidPeso molecolare:386.45RN486
CAS:RN486 is an effective and specific BTK inhibitor (IC50: 4 nM).Formula:C35H35FN6O3Purezza:99.38%Colore e forma:SolidPeso molecolare:606.69(Rac)-IBT6A
CAS:(Rac)-IBT6A is a racemate of IBT6A. IBT6A is an impurity of Ibrutinib and can be used in the synthesis of IBT6A Ibrutinib dimer and IBT6A adduct.Formula:C22H22N6OPurezza:99.24%Colore e forma:SolidPeso molecolare:386.45Ref: TM-T10626
1mg44,00€2mg57,00€1mL*10mM (DMSO)92,00€5mg93,00€10mg120,00€25mg215,00€50mg313,00€100mg439,00€200mg628,00€TL-895
CAS:TL-895 is a potent, selective ATP-competitive BTK inhibitor (IC50 = 1.5 nM, Ki = 11.9 nM).Formula:C25H26FN5O2Purezza:99.96%Colore e forma:SolidPeso molecolare:447.5Ref: TM-T9705
2mg39,00€5mg60,00€1mL*10mM (DMSO)60,00€10mg87,00€25mg172,00€50mg266,00€100mg391,00€200mg555,00€CHMFL-BMX-078
CAS:CHMFL-BMX-078 is a highly potent and selective type II irreversible BMX kinase inhibitor with an IC50 of 11 nM.Formula:C33H35N7O6Purezza:>99.99%Colore e forma:SolidPeso molecolare:625.67(S)-Sunvozertinib
CAS:(S)-Sunvozertinib (DZD9008) is a rationally designed selective, irreversible EGFR/HER2 inhibitor.Formula:C29H35ClFN7O3Purezza:99.64%Colore e forma:SolidPeso molecolare:584.08Avitinib
CAS:Avitinib (AC0010), also known as AC0010 or AC0010MA, is an orally available, irreversible, epidermal growth factor receptor (EGFR) mutant-selective inhibitor,Formula:C26H26FN7O2Purezza:99.81% - >99.99%Colore e forma:White SolidPeso molecolare:487.53CGI-1746
CAS:CGI1746 is a potent and highly selective small-molecule Btk inhibitor with IC50 of 1.9 nM.Formula:C34H37N5O4Purezza:97.69% - 97.88%Colore e forma:White SolidPeso molecolare:579.69Zanubrutinib
CAS:Zanubrutinib (BGB-3111) is an inhibitor of Bruton tyrosine kinase (BTK).Formula:C27H29N5O3Purezza:98.42% - 99.76%Colore e forma:SolidPeso molecolare:471.55Ref: TM-T7584
1mg52,00€2mg80,00€5mg124,00€1mL*10mM (DMSO)129,00€10mg215,00€25mg409,00€50mg612,00€100mg842,00€
