BTK
Gli inibitori della tirosina chinasi di Bruton (BTK) sono composti che mirano specificamente a inibire la BTK, un enzima cruciale coinvolto nella segnalazione del recettore delle cellule B e nella regolazione dell'angiogenesi. La BTK svolge un ruolo significativo nella proliferazione e nella sopravvivenza delle cellule cancerose, in particolare nelle malignità ematologiche. Inibendo la BTK, questi composti possono interrompere l'angiogenesi e la crescita tumorale, rendendoli preziosi nella terapia del cancro. Presso CymitQuimica, offriamo una gamma di inibitori della BTK di alta qualità per supportare la tua ricerca in oncologia, immunologia e angiogenesi.
Trovati 157 prodotti di "BTK"
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SJF620
CAS:SJF620 is a potent degrader of PROTAC BTK(DC50 : 7.9 nM).Formula:C41H44N8O7Purezza:98%Colore e forma:SolidPeso molecolare:760.84BTK-IN-23
CAS:BTK-IN-23: BTK inhibitor, IC50=12.8 nM; also blocks BLX (35.6 nM), BMX (5.7 nM); better selectivity than Ibrutinib.Formula:C27H28N6O2Colore e forma:SolidPeso molecolare:468.55EGFR-IN-40
CAS:EGFR-IN-40 (compound 3z) is a potent inhibitor of BTK (IC50: 1.2 nM), EGFR (IC50: 5.3 nM) and ITK (IC50: 46.1 nM).Formula:C23H20N6O3Colore e forma:SolidPeso molecolare:428.44GDC-0834 Racemate
CAS:GDC-0834 Racemate is the racemate form of GDC-0834, which is an effective and selective BTK inhibitorFormula:C33H36N6O3SColore e forma:SolidPeso molecolare:596.74BI-1622
CAS:BI-1622, an oral HER2 inhibitor, IC50: 7 nM, >25x selectivity over EGFR, shows effective in vivo antitumor activity.Formula:C26H24N10O2Colore e forma:SolidPeso molecolare:508.53PF-06465469
CAS:PF-06465469, a covalent ITK and BTK inhibitor (IC₅₀ = 2 nM), suppresses CXCL12-mediated migration and decreases PD-1/LAG-3 for leukemia and lymphoma research.Formula:C30H33N7O2Purezza:98%Colore e forma:SolidPeso molecolare:523.63(R)-Zanubrutinib
CAS:(R)-Zanubrutinib ((R)-BGB-3111) is a selective inhibitor of Bruton tyrosine kinase (BTK).Formula:C27H29N5O3Purezza:99.55%Colore e forma:SolidPeso molecolare:471.55Larotinib
CAS:Larotinib is an orally active, potent, and broad-spectrum tyrosine kinase inhibitor (TKI) with an IC50 of 0.6 nM for EGFR.Formula:C24H26ClFN4O4Purezza:99.73%Colore e forma:SolidPeso molecolare:488.94(±)-Zanubrutinib
CAS:(±)-Zanubrutinib ((±)-BGB-3111) is a potent and orally available Bruton's tyrosine kinase (Btk) inhibitor that demonstrates superior oral bioavailability,Formula:C27H29N5O3Purezza:99.09%Colore e forma:SolidPeso molecolare:471.55NX-2127
CAS:NX-2127 (ETX2514 Triethylamine) is an orally active BTK inhibitor that induces degradation of mutant BTKC481S in cells.NX-2127 has potent antiproliferativeFormula:C39H45N9O5Purezza:99.07%Colore e forma:SolidPeso molecolare:719.83Tilfrinib
CAS:<p>Tilfrinib is an effective and selective inhibitor of breast tumor kinase(Brk, IC50 = 3.15 nM) which displays anti-proliferative and anti-tumor activities.</p>Formula:C17H13N3OPurezza:99.54%Colore e forma:SolidPeso molecolare:275.3Sunvozertinib
CAS:Sunvozertinib (DZD9008) is a potent ErbBs and BTK inhibitor, with inhibitory effects on EGFR, Her2.Cost-effective and quality-assured.Formula:C29H35ClFN7O3Purezza:98.11% - 99.63%Colore e forma:SolidPeso molecolare:584.08CHMFL-EGFR-202
CAS:<p>CHMFL-EGFR-202 is a potent, irreversible inhibitor of EGFR mutant kinase (IC50s: 5.3 nM and 8.3 nM for drug-resistant mutant EGFR T790M and WT EGFR kinases).</p>Formula:C25H24ClN7O2Purezza:99.66%Colore e forma:SolidPeso molecolare:489.96BTK inhibitor 20
CAS:BTK inhibitor 20 is a potent BTK inhibitor with an IC 50 of 8 nM .Formula:C37H42N8O4Colore e forma:SolidPeso molecolare:662.78BTK-IN-11
CAS:<p>BTK-IN-11: potent BTK inhibitor; may research autoimmune, inflammatory diseases, cancer. (Patent WO2022063101A1, Z2)</p>Formula:C26H22ClN5O3Colore e forma:SolidPeso molecolare:487.94BTK-IN-17
BTK-IN-17: selective, oral BTK inhibitor, IC50=13.7 nM, reduces p-BTK Y223/p-PLCγ2 Y1217, anti-inflammatory.Formula:C26H23N7O2Colore e forma:SolidPeso molecolare:465.51BTK-IN-18
CAS:BTK-IN-18 is a potent, reversible inhibitor of Bruton's tyrosine kinase (BTK) with an inhibitory concentration (IC50) of 0.002 µM.Formula:C20H22Cl2N6OColore e forma:SolidPeso molecolare:433.33(Rac)-PF-06250112
CAS:(Rac)-PF-0625011 is a racemic mix, orally active, selective BTK inhibitor, also targeting BMX and TEC kinases.Formula:C22H20F2N6O2Purezza:98%Colore e forma:SolidPeso molecolare:438.43BTK-IN-19
CAS:BTK-IN-19 is a reversible BTK inhibitor with an IC 50 of <0.001 μM .Formula:C21H22Cl2N6OColore e forma:SolidPeso molecolare:445.35PF-303
CAS:PF-303, a reversible covalent BTK inhibitor, shows potential for cancer and autoimmune therapy.Formula:C22H21ClN6O2Colore e forma:SolidPeso molecolare:436.89
