Syk
Gli inibitori della chinasi splenica (Syk) sono composti che prendono di mira Syk, una chinasi coinvolta nella segnalazione delle cellule immunitarie e nella regolazione dell'angiogenesi. Syk svolge un ruolo nelle risposte infiammatorie che possono contribuire all'angiogenesi tumorale. L'inibizione di Syk può ridurre la formazione di vasi sanguigni indotta dall'infiammazione nei tumori, rendendo questi inibitori preziosi nella terapia del cancro e nella ricerca sull'infiammazione. Presso CymitQuimica, offriamo una gamma diversificata di inibitori di Syk di alta qualità per supportare la tua ricerca in immunologia, oncologia e angiogenesi.
Trovati 38 prodotti per "Syk".
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Piceatannol
CAS:Formula:C14H12O4Purezza:>98.0%(HPLC)Colore e forma:White to Light yellow to Light red powder to crystalPeso molecolare:244.251,3-Benzodioxole, 5-(2-nitroethenyl)-
CAS:Formula:C9H7NO4Purezza:98%Colore e forma:SolidPeso molecolare:193.15621,2-Benzenediol, 4-[(1E)-2-(3,5-dihydroxyphenyl)ethenyl]-
CAS:Formula:C14H12O4Purezza:97%Colore e forma:SolidPeso molecolare:244.2427Ref: IN-DA0002ZH
500gPrezzo su richiesta100mg23,00€1g25,00€250mg27,00€5g64,00€10g97,00€25g172,00€100g520,00€Adrenalone hydrochloride
CAS:Adrenalone HCl: α1-adrenoceptor agonist, topical hemostatic, vasoconstrictor, prolongs local anesthesia.Formula:C9H11NO3·HClPurezza:99.94%Colore e forma:SolidPeso molecolare:217.65Piceatannol
CAS:Piceatannol (Astringenin) is a synthetic anti-inflammatory that blocks p56lck, syk kinases, and NF-κB, made from resveratrol.Formula:C14H12O4Purezza:98.66% - 99.73%Colore e forma:SolidPeso molecolare:244.24Gusacitinib
CAS:Gusacitinib (ASN-002) (ASN-002) is spleen tyrosine kinase (SYK) and janus kinase (JAK) inhibitor (IC50: 5-46 nM).Formula:C24H28N8O2Purezza:98.06% - 99.94%Colore e forma:SolidPeso molecolare:460.53Ref: TM-T14331
1mg39,00€5mg84,00€1mL*10mM (DMSO)85,00€10mg116,00€25mg178,00€50mg333,00€100mg495,00€200mg710,00€Lanraplenib
CAS:Lanraplenib (GS-9876) is a highly selective and orally active SYK inhibitor (IC50=9.5 nM) in development for the treatment of inflammatory diseases.Formula:C23H25N9OPurezza:98.35%Colore e forma:SolidPeso molecolare:443.5Ref: TM-T11824LL
1mg49,00€2mg71,00€5mg94,00€1mL*10mM (DMSO)109,00€10mg159,00€25mg275,00€50mg408,00€100mg600,00€Syk-IN-4
CAS:Syk-IN-4 is a potent, oral Syk inhibitor; blocks immune signaling; used for rheumatoid arthritis research.Formula:C21H25N9OColore e forma:White SolidPeso molecolare:419.48Ref: TM-T37077
1mg141,00€5mg335,00€1mL*10mM (DMSO)358,00€10mg597,00€25mg1.189,00€50mg1.935,00€100mg2.907,00€Tyrosine Kinase Inhibitor Library
A unique collection of xnum HIF-1 related small chemicals can be used for drug discovery in ischemic disease and cancer and related mechanism studies;Colore e forma:Odour SolidRef: TM-L2200
1mgPrezzo su richiesta10μL*10mM (DMSO)Prezzo su richiesta20μL*10mM (DMSO)Prezzo su richiesta30μL*10mM (DMSO)Prezzo su richiesta50μL*10mM (DMSO)Prezzo su richiesta100μL*10mM (DMSO)Prezzo su richiesta250μL*10mM (DMSO)Prezzo su richiestaSyk Kinase Peptide Substrate, Biotin labeled
The compound, Biotin-labeled Syk Kinase Peptide Substrate, is a peptide substrate of Syk kinase that is labeled with biotin.Formula:C76H108N18O24S1Colore e forma:SolidPeso molecolare:1689.9Cevidoplenib dimesylate
CAS:Cevidoplenib dimesylate is an inhibitor of spleen tyrosine kinase (Syk), possessing anti-inflammatory and immunomodulating properties.Formula:C27H35N7O9S2Purezza:98%Colore e forma:Yellow SolidPeso molecolare:665.74Syk-IN-7
Syk-IN-7 (compound 17) acts as an inhibitor of spleen tyrosine kinase (SYK) [1].Formula:C26H31N9O4Purezza:98%Colore e forma:SolidPeso molecolare:533.58MRL-SYKi
MRL-SYKi is a highly selective and potent chemical probe for spleen tyrosine kinase (SYK). In live cell assays, it strongly binds to SYK gain-of-function (GoF) variants [SYK(S550Y), SYK(S550F), and SYK(P342T)], with IC50 values of 2.1 nM, 14 nM, and 4.6 nM in digitonin-permeabilized cell experiments. MRL-SYKi effectively reduces catalytic activity, as shown in PhosphoSens SOX peptide assays, where the IC50 for SYK(S550F) is 63 nM and for SYK(P342T) is 95 nM. Additionally, it decreases phosphorylation levels at Y525/526 of SYK(S550Y) in SW480 cells. MRL-SYKi is useful for inflammation research.Lanraplenib succinate
CAS:Lanraplenib succinate is an oral SYK inhibitor (IC50=9.5 nM) that doesn't extend BT, targeting GPVI in platelets for inflammation treatment.Formula:C58H68N18O14Colore e forma:SolidPeso molecolare:1241.294MNS
CAS:Formula:C9H7NO4Purezza:>98.0%(GC)Colore e forma:Light yellow to Yellow to Green powder to crystalPeso molecolare:193.16BAY 61-3606 dihydrochloride
CAS:BAY 61-3606 dihydrochloride (BAY 61-3606) is a potent and selective inhibitor of Syk kinase (Ki = 7.5 nM).Formula:C20H18N6O3·2HClPurezza:99.46%Colore e forma:SolidPeso molecolare:463.32Ref: TM-T6776
1mg35,00€5mg79,00€1mL*10mM (DMSO)93,00€10mg110,00€25mg177,00€50mg264,00€100mg385,00€200mg535,00€TAK-659 hydrochloride
CAS:TAK-659 hydrochloride (TAK-659) is a potent and selective inhibitor of spleen tyrosine kinase (SYK) with an IC50 value of 3.2 nM.Formula:C17H22ClFN6OPurezza:99.28% - 99.82%Colore e forma:SolidPeso molecolare:380.85BAY 61-3606
CAS:BAY 61-3606 (Syk inhibitor IV) is a potent, ATP-competitive, reversible, and highly selective inhibitor of Syk tyrosine kinase activity (Ki= 7.5 nM), exhibitingFormula:C20H18N6O3Purezza:98.72%Colore e forma:Yellow SolidPeso molecolare:390.4R112
CAS:R112 ((E)-Elafibranor) is an ATP-competitive inhibitor of Syk kinase.Formula:C16H13FN4O2Purezza:99.27% - 99.84%Colore e forma:Yellow SolidPeso molecolare:312.3Ref: TM-T3185
1mg37,00€2mg49,00€5mg79,00€1mL*10mM (DMSO)87,00€10mg117,00€25mg207,00€50mg311,00€100mg462,00€500mg973,00€Fostamatinib Disodium
CAS:Fostamatinib Disodium (R788 Disodium) is an orally available Syk kinase inhibitor with potential anti-inflammatory and immunomodulating activities.Formula:C23H24FN6O9P·2NaPurezza:96.13% - 99.09%Colore e forma:White SolidPeso molecolare:624.42Ref: TM-T2605
1mg44,00€2mg52,00€5mg84,00€1mL*10mM (DMSO)110,00€10mg117,00€25mg210,00€50mg354,00€100mg530,00€500mg1.153,00€
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