Syk
Gli inibitori della chinasi splenica (Syk) sono composti che prendono di mira Syk, una chinasi coinvolta nella segnalazione delle cellule immunitarie e nella regolazione dell'angiogenesi. Syk svolge un ruolo nelle risposte infiammatorie che possono contribuire all'angiogenesi tumorale. L'inibizione di Syk può ridurre la formazione di vasi sanguigni indotta dall'infiammazione nei tumori, rendendo questi inibitori preziosi nella terapia del cancro e nella ricerca sull'infiammazione. Presso CymitQuimica, offriamo una gamma diversificata di inibitori di Syk di alta qualità per supportare la tua ricerca in immunologia, oncologia e angiogenesi.
Trovati 39 prodotti per "Syk".
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MNS
CAS:Formula:C9H7NO4Purezza:>98.0%(GC)Colore e forma:Light yellow to Yellow to Green powder to crystalPeso molecolare:193.16Piceatannol
CAS:Formula:C14H12O4Purezza:>98.0%(HPLC)Colore e forma:White to Light yellow to Light red powder to crystalPeso molecolare:244.25Piceatannol
CAS:Piceatannol (Astringenin) is a synthetic anti-inflammatory that blocks p56lck, syk kinases, and NF-κB, made from resveratrol.Formula:C14H12O4Purezza:98.66% - 99.73%Colore e forma:SolidPeso molecolare:244.24Gusacitinib
CAS:Gusacitinib (ASN-002) (ASN-002) is spleen tyrosine kinase (SYK) and janus kinase (JAK) inhibitor (IC50: 5-46 nM).Formula:C24H28N8O2Purezza:98.06% - 99.94%Colore e forma:SolidPeso molecolare:460.5315Lanraplenib
CAS:Lanraplenib (GS-9876) is a highly selective and orally active SYK inhibitor (IC50=9.5 nM) in development for the treatment of inflammatory diseases.Formula:C23H25N9OPurezza:98.35%Colore e forma:SolidPeso molecolare:443.5043Adrenalone hydrochloride
CAS:Adrenalone HCl: α1-adrenoceptor agonist, topical hemostatic, vasoconstrictor, prolongs local anesthesia.Formula:C9H12ClNO3Purezza:99.94%Colore e forma:SolidPeso molecolare:217.649Syk-IN-4
CAS:Syk-IN-4 is a potent, oral Syk inhibitor; blocks immune signaling; used for rheumatoid arthritis research.Formula:C21H25N9OColore e forma:White SolidPeso molecolare:419.48Tyrosine Kinase Inhibitor Library
A unique collection of xnum HIF-1 related small chemicals can be used for drug discovery in ischemic disease and cancer and related mechanism studies;Colore e forma:Odour SolidSyk Kinase Peptide Substrate, Biotin labeled
The compound, Biotin-labeled Syk Kinase Peptide Substrate, is a peptide substrate of Syk kinase that is labeled with biotin.Formula:C76H108N18O24S1Colore e forma:SolidPeso molecolare:1689.9Cevidoplenib dimesylate
CAS:Cevidoplenib dimesylate is an inhibitor of spleen tyrosine kinase (Syk), possessing anti-inflammatory and immunomodulating properties.Formula:C27H35N7O9S2Purezza:98%Colore e forma:Yellow SolidPeso molecolare:665.738Syk-IN-7
Syk-IN-7 (compound 17) acts as an inhibitor of spleen tyrosine kinase (SYK) [1].Formula:C26H31N9O4Purezza:98%Colore e forma:SolidPeso molecolare:533.58MRL-SYKi
MRL-SYKi is a highly selective and potent chemical probe for spleen tyrosine kinase (SYK). In live cell assays, it strongly binds to SYK gain-of-function (GoF) variants [SYK(S550Y), SYK(S550F), and SYK(P342T)], with IC50 values of 2.1 nM, 14 nM, and 4.6 nM in digitonin-permeabilized cell experiments. MRL-SYKi effectively reduces catalytic activity, as shown in PhosphoSens SOX peptide assays, where the IC50 for SYK(S550F) is 63 nM and for SYK(P342T) is 95 nM. Additionally, it decreases phosphorylation levels at Y525/526 of SYK(S550Y) in SW480 cells. MRL-SYKi is useful for inflammation research.Lanraplenib succinate
CAS:Lanraplenib succinate is an oral SYK inhibitor (IC50=9.5 nM) that doesn't extend BT, targeting GPVI in platelets for inflammation treatment.Formula:C58H68N18O14Colore e forma:SolidPeso molecolare:1241.2943,4,3',5'-Tetrahydroxy-trans-stilbene
CAS:Formula:C14H12O4Purezza:97%Colore e forma:SolidPeso molecolare:244.2427Ref: IN-DA0002ZH
100mg25,00€250mg28,00€1g31,00€5g69,00€10g129,00€25g197,00€75g660,00€100g700,00€500g2.090,00€Fostamatinib
CAS:Fostamatinib (R788)(IC50 of 41 nM), which is a prodrug of the active metabolite R406, is a Syk inhibitor. It does not work on Lyn.Formula:C23H26FN6O9PPurezza:93.08% - 99.58%Colore e forma:SolidPeso molecolare:580.4595PRT062607 hydrochloride
CAS:PRT062607 hydrochloride (P505-15 Hydrochloride) is a selective inhibitor of Syk. PRT062607 displays at least 80-fold selectivity for Syk over other kinases.Formula:C19H24ClN9OPurezza:97.7% - 99.81%Colore e forma:SolidPeso molecolare:429.907BAY 61-3606
CAS:BAY 61-3606 (Syk inhibitor IV) is a potent, ATP-competitive, reversible, and highly selective inhibitor of Syk tyrosine kinase activity (Ki= 7.5 nM), exhibitingFormula:C20H18N6O3Purezza:98.72%Colore e forma:Yellow SolidPeso molecolare:390.3953MNS
CAS:MNS is a tyrosine kinases inhibitor, inhibits Syk, Src, p97 with IC50 of 2.5 μM, 29.3 μM and 1.7 μM, respectively.Formula:C9H7NO4Purezza:98.53%Colore e forma:Yellow SolidPeso molecolare:193.1562R112
CAS:R112 ((E)-Elafibranor) is an ATP-competitive inhibitor of Syk kinase.Formula:C16H13FN4O2Purezza:99.27% - 99.84%Colore e forma:Yellow SolidPeso molecolare:312.2984
