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ASK

ASK

Gli inibitori della chinasi regolatrice dell'apoptosi (ASK) prendono di mira la famiglia di chinasi ASK, che sono regolatori critici dell'apoptosi e delle vie di risposta allo stress. Le chinasi ASK sono coinvolte nell'attivazione dell'apoptosi in risposta a vari segnali di stress, tra cui lo stress ossidativo e i danni al DNA. Inibendo ASK, questi composti possono modulare la segnalazione apoptotica, fornendo strumenti preziosi per la ricerca sulla morte cellulare, il cancro e le malattie neurodegenerative. Presso CymitQuimica, offriamo una gamma di inibitori ASK di alta qualità per supportare la tua ricerca in apoptosi, segnalazione cellulare e meccanismi delle malattie.

Trovati 6 prodotti di "ASK"

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  • Logo CymitQuimica
    Targetmol
    + Info

    Anti-DBF4 Antibody (2Q22)

    <p>Anti-DBF4 Antibody (2Q22) is an antibody targeting DBF4. Anti-DBF4 Antibody (2Q22) can be used in ELISA, WB, IF Recommended dilution: WB:1:500-1:2000, IF:1:50-1:200.</p>
    Colore e forma:Odour Liquid

    Ref: TM-TMAH-00332

  • ASK1-IN-1
    Targetmol
    + Info

    ASK1-IN-1

    CAS:
    <p>ASK1-IN-1 inhibits apoptosis kinase 1, crucial in cell stress responses, with 21 nM IC50.</p>
    Formula:C19H19N9O2
    Purezza:99.92%
    Colore e forma:Solid
    Peso molecolare:405.41

    Ref: TM-T9697

  • MSC 2032964A
    Targetmol
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    MSC 2032964A

    CAS:
    <p>MSC 2032964A: Potent, selective ASK1 inhibitor, IC50=93 nM, oral, brain-permeable, curbs neuroinflammation, blocks LPS-induced ASK1/p38 activation.</p>
    Formula:C16H13F3N6O
    Purezza:99.76%
    Colore e forma:Solid
    Peso molecolare:362.31

    Ref: TM-T33514

  • CDK8/19-IN-1
    Targetmol
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    CDK8/19-IN-1

    CAS:
    <p>CDK8/19-IN-1 is a selective and oral bioavailable CDK8/19 dual inhibitor (IC50s: 0.46 nM, 0.99 nM, and 270 nM for CDK8, CDK19, and CDK9).</p>
    Formula:C19H18N4O4S2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:430.5

    Ref: TM-T10739

  • ASK1-IN-8
    Targetmol
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    ASK1-IN-8

    CAS:
    <p>ASK1-IN-8 (Compound 35) is an orally active inhibitor of apoptosis signal-regulating kinase 1 (ASK1) with an IC50 value of 1.8 nM. In a mouse liver injury model induced by Acetaminophen, ASK1-IN-8 significantly reduces plasma alanine aminotransferase (ALT) levels, offering liver protection. This compound is useful for research in liver disease-related fields.</p>
    Formula:C26H32N8O2
    Colore e forma:Solid
    Peso molecolare:488.585

    Ref: TM-T206247

  • ASK1-IN-7
    Targetmol
    + Info

    ASK1-IN-7

    CAS:
    <p>ASK1-IN-7 (Compound 4c) is an ASK1 inhibitor and a derivative of the ASK1 inhibitor scaffold 5-(5-Phenyl-furan-2-ylmethylene)-2-thioxo-thiazolidin-4-one. This compound is potentially applicable in research involving ASK1 signaling pathways, including studies on cellular stress response, inflammatory response, neurodegenerative diseases, and cardiovascular diseases.</p>
    Formula:C13H8N2O2S2
    Colore e forma:Solid
    Peso molecolare:288.345

    Ref: TM-T205427