TNF
Gli inibitori del fattore di necrosi tumorale (TNF) sono composti che bloccano l'attività del TNF, una citochina coinvolta nell'infiammazione e nella regolazione dell'apoptosi. Il TNF può indurre l'apoptosi in alcuni tipi di cellule mentre promuove la sopravvivenza e l'infiammazione in altri. L'inibizione del TNF è cruciale nel trattamento delle malattie autoimmuni, delle condizioni infiammatorie croniche e di alcuni tipi di cancro. Gli inibitori del TNF aiutano a modulare la risposta immunitaria e a ridurre i danni ai tessuti causati da un'infiammazione eccessiva. Presso CymitQuimica, offriamo una vasta gamma di inibitori del TNF di alta qualità per supportare la tua ricerca in immunologia, infiammazione e apoptosi.
Trovati 144 prodotti per "TNF".
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Lucatumumab
CAS:Lucatumumab (HCD122) is a fully human anti-CD40 monoclonal antibody with anti-tumor activity for the study of multiple myeloma.Purezza:95.5% (SDS-PAGE); 98.4% (SEC-HPLC) - 95.5% (SDS-PAGE); 98.4% (SEC-HPLC)Colore e forma:Transparent LiquidPeso molecolare:146.15 kDa (Predicted)UCB-9260
CAS:UCB-9260 inhibits TNF signaling by stabilizing an asymmetric form of the trimer.Formula:C26H25N5OPurezza:98.39% - 98.71%Colore e forma:White SolidPeso molecolare:423.5096Enavatuzumab
CAS:Enavatuzumab (PDL192) is a humanized monoclonal antibody targeting TWEAK receptor with anti-tumor activity.Purezza:>95%Colore e forma:Transparent LiquidPeso molecolare:~150 kDaTeneliximab
CAS:Teneliximab (BMS 224819) is a chimeric monoclonal antibody that blocks CD40-CD40L interactions.Cost-effective and quality-assured.Purezza:99.19% (SEC-HPLC) - >95.0% (SDS-PAGE)Colore e forma:LiquidPeso molecolare:146.06 kDa (Predicted)Iscalimab
CAS:Iscalimab (CFZ-533) is a humanized monoclonal antibody targeting CD40, used in research on myasthenia gravis and Sjögren’s syndrome.Purezza:>95%Colore e forma:Transparent LiquidPeso molecolare:146.08 kDa (Predicted)Conatumumab
CAS:Conatumumab (AMG 655) targets DR5 to induce apoptosis in tumors, with Kd of 1 nM (long DR5) and 0.8 nM (short DR5).Purezza:> 95% - > 95%Colore e forma:Transparent LiquidPeso molecolare:145.44 kDa (Predicted)Ozoralizumab
CAS:Ozoralizumab (ATN-103) is a humanized anti-TNFα antibody and a novel TNFα inhibitor.Purezza:SDS-PAGE:> 95%;SEC-HPLC:95.6%Colore e forma:Transparent LiquidPeso molecolare:38.44 kDa (Predicted)Ruplizumab
CAS:PF-03732010 is a humanized antibody targeting P-calmodulin with antitumor and antimetastatic activity.Purezza:98.5% (SDS-PAGE); 98.7% (SEC-HPLC) - 98.5% (SDS-PAGE); 98.7% (SEC-HPLC)Colore e forma:Transparent LiquidPeso molecolare:145.42 kDa (Predicted)HS-243
CAS:HS-243 is an inhibitor of IRAK-4 and IRAK-1 with IC50s of 20 and 24 nM. HS-243 shows anti-inflammatory and anticancer activity.Formula:C17H16N4O3Purezza:98.62%Colore e forma:SolidPeso molecolare:324.3339(S,S)-TAPI-1 FA
(S,S)-TAPI-1 FA is a TNF-α processing inhibitor with potential anti-inflammatory effects, blocks TACE, and can inhibit TNF-α signaling can be used to study Staphylococcus aureus arthritis.Formula:C27H39N5O7Purezza:97.61% - 98.23%Colore e forma:Yellow SolidPeso molecolare:545.63Dacetuzumab
CAS:Dacetuzumab (SGN 40) is a humanized anti-CD40 monoclonal antibody with antitumor activity for the study of recurrent diffuse large B-cell lymphoma.Purezza:95.4% (SDS-PAGE); 99.1% (SEC-HPLC) - 95.4% (SDS-PAGE); 99.1% (SEC-HPLC)Colore e forma:Transparent LiquidPeso molecolare:145.1 kDa (Predicted)Utomilumab
CAS:Utomilumab, a humanized IgG2 against T-cell receptor 4-1BB/CD137, shows antitumor effects in advanced cancers.Formula:C17H24N8O3Purezza:95% - 95.1% (SDS-PAGE); 98.5% (SEC-HPLC)Colore e forma:Transparent LiquidPeso molecolare:142.77 kDa (Predicted)Anti-Mouse OX40L/CD134L Antibody (RM134L)
Anti-Mouse OX40L/CD134L Antibody (RM134L) attenuates immune response, used in inflammation and cancer research.Purezza:95% - 97.6% (SDS-PAGE); 99.5% (SEC-HPLC)Peso molecolare:144.63 kDa (Predicted)KGYY15
CAS:KGYY15 (Mouse KGYY15), a peptide that targets CD40, exhibits weak inhibition of the CD40-CD40L interaction, with an IC50 exceeding 1 mM. At a concentration of 100 μM, KGYY15 activates the NF-κB pathway by 33%.Formula:C84H129N21O22SColore e forma:SolidPeso molecolare:1817.12Varlilumab
CAS:Varlilumab (CDX-1127) is a novel human IgG1 anti-CD27 monoclonal antibody. Varlilumab has antitumor activity and can be used to study advanced solid tumors.Purezza:SDS-PAGE:95% SEC-HPLC:98.65%Colore e forma:Transparent LiquidPeso molecolare:146 kDa (Predicted)Tengonermin
CAS:Tengonermin (ARENEGYR), a vascular agent, is TNF-α fused with CNGRCG peptide, enhancing chemo and T-cell access in tumors.Colore e forma:LiquidLenercept
CAS:Lenercept (Ro 45-2081) is a recombinant fusion protein combining the soluble TNF-receptor (p55) with the Fc portion of human IgG1 [1].Colore e forma:LiquidIspectamab
Ispectamab is an anti-TNFRSF17 human monoclonal antibody for research on TNFRSF17-associated biology.Peso molecolare:~148 kDaRagifilimab
CAS:Ragifilimab (INCAGN-1876), a GITR-targeting agonist antibody, may treat advanced solid tumors.Purezza:SDS-PAGE:95% SEC-HPLC:99.99%Colore e forma:Transparent LiquidPeso molecolare:146.46 kDa (Predicted)TNF-α (46-65), human
CAS:Human TNF alpha (46-65) peptide.Formula:C110H172N24O30Purezza:98%Colore e forma:SolidPeso molecolare:2310.69
