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TNF

TNF

Gli inibitori del fattore di necrosi tumorale (TNF) sono composti che bloccano l'attività del TNF, una citochina coinvolta nell'infiammazione e nella regolazione dell'apoptosi. Il TNF può indurre l'apoptosi in alcuni tipi di cellule mentre promuove la sopravvivenza e l'infiammazione in altri. L'inibizione del TNF è cruciale nel trattamento delle malattie autoimmuni, delle condizioni infiammatorie croniche e di alcuni tipi di cancro. Gli inibitori del TNF aiutano a modulare la risposta immunitaria e a ridurre i danni ai tessuti causati da un'infiammazione eccessiva. Presso CymitQuimica, offriamo una vasta gamma di inibitori del TNF di alta qualità per supportare la tua ricerca in immunologia, infiammazione e apoptosi.

Trovati 91 prodotti di "TNF"

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  • BMS-986156


    BMS-986156 is a fully humanized IgG1 agonist monoclonal antibody that targets the glucocorticoid-induced tumor necrosis factor receptor-related protein (GITR). It binds to GITR and enhances the activation of T effector cells while deactivating T regulatory cells. BMS-986156 is applicable for research in advanced solid tumors.
  • Pamlectabart


    Pamlectabart is a humanised antibody targeting TNFRSF17/BCMA, (ADC) Pamlectabart tismanitin multiple myeloma.
    Purezza:95%
    Colore e forma:Odour Liquid
  • TNF-α-IN-9

    CAS:
    TNF-α-IN-9 is an NDM-1 inhibitor-3 analog and is a TNF-α inhibitor.TNF-α-IN-9 shows low inhibitory activity.
    Formula:C17H14O4
    Purezza:99.21%
    Colore e forma:Soild
    Peso molecolare:282.29
  • Zigakibart

    CAS:
    Zigakibart (BION-1301) is a humanized monoclonal antibody targeting TNFSF13 with anti-inflammatory activity for the study of immunoglobulin A nephropathy (IgAN)
    Purezza:95.8% (SDS-PAGE); 99.8% (SEC-HPLC) - 95.8% (SDS-PAGE); 99.8% (SEC-HPLC)
    Colore e forma:Liquid
  • Relfovetmab

    CAS:
    Relfovetmab is an anti- NGF monoclonal antibody (mAb) [1] .
    Colore e forma:Liquid
  • Onfekafusp alfa

    CAS:
    Onfekafusp alfa (L19TNF), a trimeric fusion of L19 scFv and human TNF, targets malignant glioma.
    Colore e forma:Liquid
  • Tanfanercept

    CAS:
    Tanfanercept (HL036337) is an anti-TNF-α antibody, improving corneal erosions in dry eye mice.
    Colore e forma:Liquid
  • Pegsunercept

    CAS:
    Pegsunercept (PEG sTNF-RI), a pegylated monoclonal antibody, selectively binds to TNFA, incorporating a polyethylene glycol (pegol) moiety [1].
    Colore e forma:Liquid
  • RO7567132


    RO7567132 is a bispecific antibody that binds and agonizes LTBR bivalently while binds and antagonizes FAP monovalently, inducing the formation of local TLS.
    Colore e forma:Odour Liquid
  • Nerelimomab

    CAS:
    Nerelimomab (BAYX1351), an anti-TNF-α antibody, is utilized in sepsis research [1] [2].
    Colore e forma:Liquid
  • Telitacicept

    CAS:
    Telitacicept (RC18), a fully human TACI-Fc fusion protein, acts as a dual inhibitor of B lymphocyte stimulator (BLyS) and APRIL (a proliferation-inducing ligand
    Colore e forma:Liquid
  • Giloralimab

    CAS:
    Giloralimab (ABBV-927) is a antibody targeting CD40 with anticancer activity for the study of triple-negative breast cancer and non-small cell lung cancer.
    Purezza:95.6% (SDS-PAGE); 95.1% (SEC-HPLC) - 95.6% (SDS-PAGE); 95.1% (SEC-HPLC)
    Colore e forma:Liquid
  • Placulumab

    CAS:
    Placulumab (ART621), an anti-TNF α monoclonal antibody, targets inflammation, potentially aiding arthritis treatment.
    Colore e forma:Liquid
  • TNF-α Antagonist

    CAS:
    TNF-α antagonist is an exocyclic peptide that mimics the critical TNF-α recognition loop on TNF receptor I complex and, thus, prevents ligand interaction with
    Formula:C58H71N11O15S2
    Colore e forma:Solid
    Peso molecolare:1226.39
  • Sotigalimab

    CAS:
    Sotigalimab (APX 005) is a monoclonal antibody targeting CD40 with anticancer activity for the study of metastatic pancreatic cancer.
    Purezza:98.50% - 98.50%
    Colore e forma:Liquid
  • Varlilumab

    CAS:
    <p>Varlilumab (CDX-1127) is a novel human IgG1 anti-CD27 monoclonal antibody. Varlilumab has antitumor activity and can be used to study advanced solid tumors.</p>
    Purezza:SDS-PAGE:95% SEC-HPLC:98.65%
    Colore e forma:Liquid
    Peso molecolare:146 kDa
  • Asunercept

    CAS:
    <p>Asunercept (APG101/CAN008) is a CD95-Fc protein targeting CD95L, used in GBM, MDS, and GvHD research.</p>
    Colore e forma:Liquid
  • Atibuclimab

    CAS:
    <p>Atibuclimab is a chimeric monoclonal antibody targeting CD14, consisting of a mouse variable region and a human IgG4 Fc region.</p>
    Purezza:> 95% - > 95%
    Colore e forma:Liquid
    Peso molecolare:145.28 kDa
  • Ranevetmab

    CAS:
    Ranevetmab (NV-01), a caninized anti-NGF mAb, relieves pain in DJD research.
    Colore e forma:Liquid
  • BIIB023


    BIIB023 is a human monoclonal antibody (mAb) that targets TNFRSF12A/TWEAKR/CD266. It is applicable for research in lupus nephritis and rheumatoid arthritis.
    Colore e forma:Odour Liquid