TNF
Gli inibitori del fattore di necrosi tumorale (TNF) sono composti che bloccano l'attività del TNF, una citochina coinvolta nell'infiammazione e nella regolazione dell'apoptosi. Il TNF può indurre l'apoptosi in alcuni tipi di cellule mentre promuove la sopravvivenza e l'infiammazione in altri. L'inibizione del TNF è cruciale nel trattamento delle malattie autoimmuni, delle condizioni infiammatorie croniche e di alcuni tipi di cancro. Gli inibitori del TNF aiutano a modulare la risposta immunitaria e a ridurre i danni ai tessuti causati da un'infiammazione eccessiva. Presso CymitQuimica, offriamo una vasta gamma di inibitori del TNF di alta qualità per supportare la tua ricerca in immunologia, infiammazione e apoptosi.
Trovati 93 prodotti di "TNF"
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Ruplizumab
CAS:PF-03732010 is a humanized antibody targeting P-calmodulin with antitumor and antimetastatic activity.Purezza:98.5% (SDS-PAGE); 98.7% (SEC-HPLC) - 98.5% (SDS-PAGE); 98.7% (SEC-HPLC)Colore e forma:LiquidConatumumab
CAS:Conatumumab (AMG 655) targets DR5 to induce apoptosis in tumors, with Kd of 1 nM (long DR5) and 0.8 nM (short DR5).Purezza:> 95% - > 95%Colore e forma:LiquidPeso molecolare:145 kDa (average)Enavatuzumab
CAS:Enavatuzumab (PDL192) is a humanized monoclonal antibody targeting TWEAK receptor with anti-tumor activity.Purezza:>95%Colore e forma:LiquidIscalimab
CAS:Iscalimab (CFZ-533) is a humanized monoclonal antibody targeting CD40, used in research on myasthenia gravis and Sjögren’s syndrome.Purezza:>95%Colore e forma:LiquidOzoralizumab
CAS:Ozoralizumab (ATN-103) is a humanized anti-TNFα antibody and a novel TNFα inhibitor.Purezza:SDS-PAGE:> 95%;SEC-HPLC:95.6%Colore e forma:LiquidPeso molecolare:38.44 kDaUtomilumab
CAS:Utomilumab, a humanized IgG2 against T-cell receptor 4-1BB/CD137, shows antitumor effects in advanced cancers.Formula:C17H24N8O3Purezza:95% - 95.1% (SDS-PAGE); 98.5% (SEC-HPLC)Colore e forma:LiquidPeso molecolare:142.77 kDaCertolizumab pegol
CAS:<p>Certolizumab pegol (Certolizumab) is a polyethylene glycolized and humanized anti-TNF-α monoclonal antibody.</p>Purezza:95% - 98.2% (SDS-PAGE); 99.1% (SEC-HPLC)Colore e forma:LiquidTeneliximab
CAS:<p>Teneliximab (BMS 224819) is a chimeric monoclonal antibody that blocks CD40-CD40L interactions.Cost-effective and quality-assured.</p>Purezza:95.00% - 99.19% (SEC-HPLC)Colore e forma:LiquidPeso molecolare:146.06 kDaDacetuzumab
CAS:Dacetuzumab (SGN 40) is a humanized anti-CD40 monoclonal antibody with antitumor activity for the study of recurrent diffuse large B-cell lymphoma.Purezza:95.4% (SDS-PAGE); 99.1% (SEC-HPLC) - 95.4% (SDS-PAGE); 99.1% (SEC-HPLC)Colore e forma:Liquid(S,S)-TAPI-1 FA
(S,S)-TAPI-1 FA is a TNF-α processing inhibitor with potential anti-inflammatory effects, blocks TACE, and can inhibit TNF-α signaling can be used to study Staphylococcus aureus arthritis.Formula:C27H39N5O7Purezza:97.61% - 99.72%Colore e forma:SolidPeso molecolare:545.63Lucatumumab
CAS:<p>Lucatumumab (HCD122) is a fully human anti-CD40 monoclonal antibody with anti-tumor activity for the study of multiple myeloma.</p>Purezza:95.5% (SDS-PAGE); 98.4% (SEC-HPLC) - 95.5% (SDS-PAGE); 98.4% (SEC-HPLC)Colore e forma:LiquidUCB-9260
CAS:UCB-9260 inhibits TNF signaling by stabilizing an asymmetric form of the trimer.Formula:C26H25N5OPurezza:98.39% - 99.24%Colore e forma:SolidPeso molecolare:423.51Ref: TM-T13951
1mg97,00€2mgPrezzo su richiesta5mg230,00€10mg373,00€25mg635,00€50mg847,00€100mg1.169,00€200mgPrezzo su richiesta1mL*10mM (DMSO)259,00€Tilogotamab
CAS:Tilogotamab (GEN-1029) is an agonistic hexameric complex targeting two independent epitopes on DR5, used for studying multiple myeloma (MM).Purezza:95%Colore e forma:LiquidOnfekafusp alfa
CAS:Onfekafusp alfa (L19TNF), a trimeric fusion of L19 scFv and human TNF, targets malignant glioma.Colore e forma:LiquidTengonermin
CAS:Tengonermin (ARENEGYR), a vascular agent, is TNF-α fused with CNGRCG peptide, enhancing chemo and T-cell access in tumors.Colore e forma:LiquidPegsunercept
CAS:Pegsunercept (PEG sTNF-RI), a pegylated monoclonal antibody, selectively binds to TNFA, incorporating a polyethylene glycol (pegol) moiety [1].Colore e forma:LiquidZigakibart
CAS:Zigakibart (BION-1301) is a humanized monoclonal antibody targeting TNFSF13 with anti-inflammatory activity for the study of immunoglobulin A nephropathy (IgAN)Purezza:95.8% (SDS-PAGE); 99.8% (SEC-HPLC) - 95.8% (SDS-PAGE); 99.8% (SEC-HPLC)Colore e forma:LiquidNerelimomab
CAS:Nerelimomab (BAYX1351), an anti-TNF-α antibody, is utilized in sepsis research [1] [2].Colore e forma:LiquidAcetyl tetrapeptide-2
CAS:Acetyl tetrapeptide-2 is a skin conditioner, by soothing and nourishing the skin through similar mechanisms as other peptides.Formula:C26H39N5O9Purezza:98%Colore e forma:SolidPeso molecolare:565.62Telitacicept
CAS:Telitacicept (RC18), a fully human TACI-Fc fusion protein, acts as a dual inhibitor of B lymphocyte stimulator (BLyS) and APRIL (a proliferation-inducing ligandColore e forma:LiquidDSTYSLSSTLTLSK TFA
DSTYSLSSTLTLSK TFA detects infliximab, a chimeric IgG1 antibody targeting TNF-α.Formula:C66H108F3N15O28Colore e forma:SolidPeso molecolare:1616.64BMS-986156
BMS-986156 is a fully humanized IgG1 agonist monoclonal antibody that targets the glucocorticoid-induced tumor necrosis factor receptor-related protein (GITR). It binds to GITR and enhances the activation of T effector cells while deactivating T regulatory cells. BMS-986156 is applicable for research in advanced solid tumors.Dazodalibep
CAS:Dazodalibep (MEDI 4920; VIB 4920) is a monoclonal antibody that specifically targets CD40LG/TNFSF5 and is fused to human serum albumin (ALB/HSA) [1].Colore e forma:LiquidSym029
Sym029 is a human IgG monoclonal antibody (mAb) that targets TNFRSF5/CD40. It is applicable for cancer research. The suggested isotype control is Human IgG1 kappa, Isotype Control.Ragifilimab
CAS:<p>Ragifilimab (INCAGN-1876), a GITR-targeting agonist antibody, may treat advanced solid tumors.</p>Purezza:SDS-PAGE:95% SEC-HPLC:99.99%Colore e forma:LiquidPeso molecolare:146.46 kDaVarlilumab
CAS:Varlilumab (CDX-1127) is a novel human IgG1 anti-CD27 monoclonal antibody. Varlilumab has antitumor activity and can be used to study advanced solid tumors.Purezza:SDS-PAGE:95% SEC-HPLC:98.65%Colore e forma:LiquidPeso molecolare:146 kDaTNF-α-IN-9
CAS:TNF-α-IN-9 is an NDM-1 inhibitor-3 analog and is a TNF-α inhibitor.TNF-α-IN-9 shows low inhibitory activity.Formula:C17H14O4Purezza:99.21%Colore e forma:SoildPeso molecolare:282.29Anti-Mouse TNF α Antibody (TN3-19.12)
<p>Anti-Mouse TNF alpha Antibody is a rat-derived IgG inhibitor targeting mouse TNF alpha.</p>Purezza:95% - ＞10mg/mlColore e forma:Odour LiquidRO7567132
RO7567132 is a bispecific antibody that binds and agonizes LTBR bivalently while binds and antagonizes FAP monovalently, inducing the formation of local TLS.Colore e forma:Odour LiquidPamlectabart
Pamlectabart is a humanised antibody targeting TNFRSF17/BCMA, (ADC) Pamlectabart tismanitin multiple myeloma.Purezza:95%Colore e forma:Odour LiquidKGYY15
CAS:KGYY15 (Mouse KGYY15), a peptide that targets CD40, exhibits weak inhibition of the CD40-CD40L interaction, with an IC50 exceeding 1 mM. At a concentration of 100 μM, KGYY15 activates the NF-κB pathway by 33%.Formula:C84H129N21O22SPeso molecolare:1817.12BIIB023
BIIB023 is a human monoclonal antibody (mAb) that targets TNFRSF12A/TWEAKR/CD266. It is applicable for research in lupus nephritis and rheumatoid arthritis.Colore e forma:Odour LiquidTNF-α Antagonist
CAS:TNF-α antagonist is an exocyclic peptide that mimics the critical TNF-α recognition loop on TNF receptor I complex and, thus, prevents ligand interaction withFormula:C58H71N11O15S2Colore e forma:SolidPeso molecolare:1226.39Giloralimab
CAS:Giloralimab (ABBV-927) is a antibody targeting CD40 with anticancer activity for the study of triple-negative breast cancer and non-small cell lung cancer.Purezza:95.6% (SDS-PAGE); 95.1% (SEC-HPLC) - 95.6% (SDS-PAGE); 95.1% (SEC-HPLC)Colore e forma:LiquidSotigalimab
CAS:Sotigalimab (APX 005) is a monoclonal antibody targeting CD40 with anticancer activity for the study of metastatic pancreatic cancer.Purezza:98.50% - 98.50%Colore e forma:LiquidTulinercept
CAS:Tulinercept (OPRX-106), a monoclonal antibody, may be utilized in a range of biochemical research applications [1].Colore e forma:LiquidTNF-α (46-65), human
CAS:Human TNF alpha (46-65) peptide.Formula:C110H172N24O30Purezza:98%Colore e forma:SolidPeso molecolare:2310.69EJMC-1
CAS:EJMC-1 is an inhibitor of TNF-α with an IC50 value of 42 μM and can be used in studies about auto-inflammatory diseases.Formula:C17H11ClN2O4SPurezza:98.38%Colore e forma:SolidPeso molecolare:374.8Asunercept
CAS:Asunercept (APG101/CAN008) is a CD95-Fc protein targeting CD95L, used in GBM, MDS, and GvHD research.Colore e forma:LiquidHS-243
CAS:<p>HS-243 is an inhibitor of IRAK-4 and IRAK-1 with IC50s of 20 and 24 nM. HS-243 shows anti-inflammatory and anticancer activity.</p>Formula:C17H16N4O3Purezza:98.62%Colore e forma:SolidPeso molecolare:324.33Dapirolizumab
Dapirolizumab is an anti-CD40 monoclonal antibody used in research on systemic lupus erythematosus (SLE) and other autoimmune diseases.Purezza:>95%Colore e forma:LiquidPeso molecolare:150 kDaMK-4166
MK-4166 is a humanized IgG1 agonistic monoclonal antibody targeting GITR. It is capable of enhancing the proliferation of both naive T lymphocytes and tumor-infiltrating T lymphocytes.Tanfanercept
CAS:Tanfanercept (HL036337) is an anti-TNF-α antibody, improving corneal erosions in dry eye mice.Colore e forma:LiquidPlaculumab
CAS:Placulumab (ART621), an anti-TNF α monoclonal antibody, targets inflammation, potentially aiding arthritis treatment.Colore e forma:LiquidRanevetmab
CAS:Ranevetmab (NV-01), a caninized anti-NGF mAb, relieves pain in DJD research.Colore e forma:LiquidLenercept
CAS:Lenercept (Ro 45-2081) is a recombinant fusion protein combining the soluble TNF-receptor (p55) with the Fc portion of human IgG1 [1].Colore e forma:LiquidAtibuclimab
CAS:<p>Atibuclimab is a chimeric monoclonal antibody targeting CD14, consisting of a mouse variable region and a human IgG4 Fc region.</p>Purezza:> 95% - > 95%Colore e forma:LiquidPeso molecolare:145.28 kDaTNF α Protein, Human, Recombinant (aa 77-233, His)
TNF alpha Protein, Human, Recombinant (aa 77-233, His) is expressed in E.Purezza:Greater than 95% as determined by reducing SDS-PAGE - SDS-PAGE: 99.66%; SEC-HPLC: 96.3%Colore e forma:Lyophilized PowderPeso molecolare:16 KDa (reducing condition)Ref: TM-TMPJ-00124
1mg1.074,00€5µg45,00€10µg63,00€20µg92,00€50µg137,00€100µg221,00€200µg373,00€500µg749,00€TNF α Protein, Human, Recombinant (His & Avi), Biotinylated
TNF alpha Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag.Colore e forma:Lyophilized PowderPeso molecolare:20.3 kDa (predicted). Due to glycosylation, the protein migrates to 21-24 kDa based on Tris-Bis PAGE result.Ref: TM-TMPK-00121
5µg97,00€10µg157,00€20µg252,00€50µg497,00€100µg823,00€200µg1.488,00€500µg3.185,00€
