IAP
Gli inibitori delle proteine inibitorie dell'apoptosi (IAP) sono composti che bloccano l'attività delle IAP, una famiglia di proteine che prevengono l'apoptosi inibendo le caspasi e altri componenti della macchina apoptotica. Gli inibitori delle IAP promuovono l'apoptosi nelle cellule tumorali neutralizzando questi segnali di sopravvivenza, rendendoli strumenti importanti nella ricerca sul cancro e nella terapia. Presso CymitQuimica, offriamo una gamma completa di inibitori delle IAP di alta qualità per supportare la tua ricerca in oncologia, apoptosi e sviluppo terapeutico.
Trovati 67 prodotti di "IAP"
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MV1
CAS:MV1 is an IAP antagonist. When combined with HaloTag ligand, MV1 causes protein knockdown of HaloTag-fused proteins.Formula:C33H44N4O5Purezza:99.86%Colore e forma:SolidPeso molecolare:576.73SBP-0636457
CAS:SBP-0636457: SMAC mimetic, IAP inhibitor, binds BIR-domains (Ki=0.27μM), potential in tumor/cancer research.Formula:C25H36N4O4Colore e forma:SolidPeso molecolare:456.587SM-164 Hydrochloride (957135-43-2 free base)
SM-164 Hydrochloride: cell-permeable, binds to XIAP (BIR2/3 domains), IC50 of 1.39 nM, potent XIAP antagonist.Formula:C62H85ClN14O6Purezza:98%Colore e forma:SolidPeso molecolare:1157.88CST626
CAS:CST626 is a PROTAC degrader that targets XIAP, cIAP1, and cIAP2.Formula:C61H82N8O9SPurezza:95.87%Colore e forma:SolidPeso molecolare:1103.42XIAP BIR2/BIR2-3 inhibitor-1
CAS:XIAP BIR2/BIR2-3 inhibitor-1 (compound 3) serves as a potent dual inhibitor targeting BIR2 and BIR2-3 domains, with IC50 values of 1.9 nM and 0.8 nM, respectively. This compound is utilized in cancer research studies [1].Formula:C72H96N16O14Colore e forma:SolidPeso molecolare:1409.63S2/IAPinh
S2/IAPinh is a conjugate composed of an inhibitor of apoptosis proteins inhibitor (IAPinh) and a ligand of sigma 2 SW43. It demonstrates anti-proliferative and apoptosis-inducing activity by degrading inhibitor of apoptosis proteins (clAP-1).Formula:C52H75Cl2FN6O6SPeso molecolare:1000.48299XIAP BIR2/BIR2-3 inhibitor-3
CAS:XIAP BIR2/BIR2-3 Inhibitor-3 functions as a dual inhibitor targeting both BIR2 and BIR2-3 domains, exhibiting potent activity with IC50 values below 1 nM. This compound is utilized in cancer research [1].Formula:C86H106N18O16S2Colore e forma:SolidPeso molecolare:1712MDM2/XIAP-IN-1
MDM2/XIAP-IN-1 (compound 14) is an orally active dual inhibitor of MDM2 and XIAP, exhibiting anti-cancer activity with an IC50 of 0.3 μM and potentialColore e forma:Odour SolidAnti-CD47 Antibody (8A121)
Anti-CD47 Antibody (8A121) is a Mouse antibody targeting CD47. Anti-CD47 Antibody (8A121) can be used in ELISA.Colore e forma:Odour LiquidAnti-CD47 Antibody (8K78)
<p>Anti-CD47 Antibody (8K78) is a Rabbit antibody targeting CD47. Anti-CD47 Antibody (8K78) can be used in WB,ELISA,IP.</p>Colore e forma:Odour LiquidAnti-CD47 Antibody (4E249)
Anti-CD47 Antibody (4E249) is a Rabbit antibody targeting CD47. Anti-CD47 Antibody (4E249) can be used in ELISA.Colore e forma:Odour LiquidAnti-CD47 Antibody (5R542)
Anti-CD47 Antibody (5R542) is a Mouse antibody targeting CD47. Anti-CD47 Antibody (5R542) can be used in ELISA.Colore e forma:Odour LiquidAnti-CD47 Antibody (5K435)
<p>Anti-CD47 Antibody (5K435) is an antibody targeting CD47. Anti-CD47 Antibody (5K435) can be used in ELISA, WB, IHC, IF.</p>Colore e forma:Odour LiquidAnti-CD47 Antibody-PE (9X161)
<p>Anti-CD47 Antibody-PE (9X161) is a PE-conjugated Mouse antibody targeting CD47. Anti-CD47 Antibody-PE (9X161) can be used in FCM.</p>Colore e forma:Odour LiquidAnti-CD47 Antibody (5S892)
Anti-CD47 Antibody (5S892) is a Mouse antibody targeting CD47. Anti-CD47 Antibody (5S892) can be used in IHC-P.Colore e forma:Odour LiquidAnti-CD47 Antibody (9X161)
Anti-CD47 Antibody (9X161) is a Mouse antibody targeting CD47. Anti-CD47 Antibody (9X161) can be used in FCM.Colore e forma:Odour LiquidAnti-CD47 Antibody-FITC (9X161)
<p>Anti-CD47 Antibody-FITC (9X161) is a FITC-conjugated Mouse antibody targeting CD47. Anti-CD47 Antibody-FITC (9X161) can be used in FCM.</p>Colore e forma:Odour LiquidAnti-CD47 Antibody (4C168)
Anti-CD47 Antibody (4C168) is a Mouse antibody targeting CD47. Anti-CD47 Antibody (4C168) can be used in IHC-P.Colore e forma:Odour LiquidAnti-CD47 Antibody (6T428)
Anti-CD47 Antibody (6T428) is a Rabbit antibody targeting CD47. Anti-CD47 Antibody (6T428) can be used in ELISA.Colore e forma:Odour LiquidAnti-CD47 Antibody (5E321)
Anti-CD47 Antibody (5E321) is a Rabbit antibody targeting CD47. Anti-CD47 Antibody (5E321) can be used in ELISA.Colore e forma:Odour LiquidAnti-CD47 Antibody (1F304)
Anti-CD47 Antibody (1F304) is an antibody targeting CD47. Anti-CD47 Antibody (1F304) can be used in ELISA, FCM.Colore e forma:Odour LiquidAZD5582
CAS:AZD5582 is an inhibitor of IAPs, which binds to the BIR3 domains cIAP1, cIAP2, and XIAP with IC50s of 15, 21, and 15 nM, respectively. It induces apoptosis.Formula:C58H78N8O8Purezza:98.75%Colore e forma:SolidPeso molecolare:1015.29CD47 Protein, Mouse, Recombinant (His)
CD47 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Purezza:SDS-PAGE: 98.3%; SEC-HPLC: 98.5%Colore e forma:Lyophilized PowderPeso molecolare:15.3 kDa (predicted); 34-44 kDa (reducing condition, due to glycosylation)Alkaline Phosphatase/PLAP Protein, Human, Recombinant (His)
Most importantly, placental alkaline phosphatase (ALPP), an ectoenzyme that locates on cell surface with catalytic domains outside the plasma membrane and isPurezza:92.7%Colore e forma:Lyophilized PowderPeso molecolare:54.1 kDa (predicted); 66 kDa (reducing conditions)CD47 Protein, Human, Recombinant (Avi & His), Biotinylated
CD47 Protein, Human, Recombinant (Avi & His), Biotinylated is expressed in HEK293 mammalian cells with C-Avi-6xHis tag.Colore e forma:Lyophilized PowderPeso molecolare:30-40 KDa (reducing condition)CD47 Protein, Human, Recombinant (hFc)
CD47 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.Purezza:> 95% as determined by Bis-Tris PAGE > 95% as determined by HPLC - > 95% as determined by Bis-Tris PAGE > 95% as determined by HPLCColore e forma:Lyophilized PowderPeso molecolare:40.5 kDa (predicted); 55-65 kDa (reducing condition, due to glycosylation)CD47 Protein, Human, Recombinant (mFc)
CD47 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag.Colore e forma:Lyophilized PowderPeso molecolare:48-65 KDa (reducing condition)CD47 Protein, Rhesus macaque, Recombinant (hFc)
<p>CD47 Protein, Rhesus macaque, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag.</p>Colore e forma:Lyophilized PowderPeso molecolare:60-90 KDa (reducing condition)CD47 Protein, Human, Recombinant (aa 19-139, His)
<p>CD47 Protein, Human, Recombinant (aa 19-139, His) is expressed in HEK293 mammalian cells with His tag.</p>Colore e forma:Lyophilized PowderPeso molecolare:14.5 kDa (predicted); 40-55 kDa (reducing conditions)Alkaline phosphatase (Intestinal type) /ALPI Protein, Human, Recombinant (His & Flag)
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletalColore e forma:Lyophilized PowderPeso molecolare:54.5 kDa (predicted). Due to glycosylation, the protein migrates to 63-73 kDa based on Tris-Bis PAGE result.CD47 Protein, Human, Recombinant (hFc & Avi), Biotinylated
CD47 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-Fc-Avi tag.Colore e forma:Lyophilized PowderPeso molecolare:60-70 KDa (reducing condition)Alkaline phosphatase (Intestinal type) /ALPI Protein, Mouse, Recombinant (His)
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletalColore e forma:Lyophilized PowderPeso molecolare:53.10 kDa (predicted). Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.CD47 Protein, Rhesus macaque, Recombinant (His & Flag)
CD47, also known as Integrin‑Associated Protein (IAP) and OA3, is a glycosylated atypical member of the immunoglobulin superfamily.Colore e forma:Lyophilized PowderPeso molecolare:33-55 KDa (reducing condition)CD47 Protein, Mouse, Recombinant (His & Avi), Biotinylated
CD47 Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag.Colore e forma:Lyophilized PowderPeso molecolare:17.1 kDa (predicted); 38.8 kDa (reducing conditions)Alkaline phosphatase/ALPI Protein, Human, Recombinant (hFc)
Alkaline phosphatase Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.Colore e forma:Lyophilized PowderPeso molecolare:79.5 kDa (predicted); 90-95 kDa (reducing condition, due to glycosylation)CD47 Protein, Human, Recombinant (aa 1-139, His)
CD47 Protein, Human, Recombinant (aa 1-139, His) is expressed in HEK293 mammalian cells with His tag.Purezza:SDS-PAGE: 98.4%; SEC-HPLC: 97.6%Colore e forma:Lyophilized PowderPeso molecolare:15.2 kDa (predicted); 35-44 kDa (reducing condition, due to glycosylation)CD47 Protein, Human, Recombinant (His)
CD47 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag.Purezza:Greater than 95% as determined by reducing SDS-PAGE. - SDS-PAGE: 100%; SEC-HPLC: 97%Colore e forma:Lyophilized PowderPeso molecolare:30-45 KDa (reducing condition)CD47 Protein, Human, Recombinant, Biotinylated
CD47 Protein, Human, Recombinant, Biotinylated is expressed in HEK293 mammalian cells.Purezza:97.6%Colore e forma:Lyophilized PowderPeso molecolare:14.5 kDa (predicted)CD47 Protein, Mouse, Recombinant
CD47 Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 13.8 kDa and the accession number is E5Q371.Colore e forma:Lyophilized PowderPeso molecolare:13.8 kDa (predicted)CD47 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)
CD47 (Cluster of Differentiation 47) also known as integrin associated protein (IAP) is a transmembrane protein that in humans is encoded by the CD47 gene.Colore e forma:Lyophilized PowderPeso molecolare:15 kDa (predicted). Due to glycosylation, the protein migrates to 45-65 kDa based on Tris-Bis PAGE result.CD47 Protein, Mouse, Recombinant (hFc)
CD47 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.Colore e forma:Lyophilized PowderPeso molecolare:40.6 kDa (predicted)CD47 Protein, Human, Recombinant
CD47 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 14.5 kDa and the accession number is Q08722-3.Purezza:97.8%Colore e forma:Lyophilized PowderPeso molecolare:14.5 kDa (predicted); 35 kDa (reducing condition, due to glycosylation)Alkaline phosphatase/ALPI Protein, Human, Recombinant (His)
Alkaline phosphatase Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Purezza:98.4%Colore e forma:Lyophilized PowderPeso molecolare:54 kDa (predicted); 66 kDa (reducing condition, due to glycosylation)CD47 Protein, Mouse, Recombinant (rFc)
CD47 Protein, Mouse, Recombinant (rFc) is expressed in HEK293 mammalian cells with rFc tag.Colore e forma:Lyophilized PowderPeso molecolare:39.9 kDa (predicted)Embelin
CAS:Embelin (Embelic acid), isolated from the Japanese Ardisia herb, is an inhibitor of the X-linked inhibitor of apoptosis (IC50: 4.1 uM).Formula:C17H26O4Purezza:97.07% - 99.88%Colore e forma:SolidPeso molecolare:294.39Polygalacin D
CAS:Polygalacin D shows anti- proliferation, anti-inflammary, and hepatoprotective activities, it can inhibit the expression of lipopolysaccharide (LPS)-inducedFormula:C57H92O27Purezza:98.95% - ≥98%Colore e forma:SolidPeso molecolare:1209.4GDC-0152
CAS:GDC-0152 is a potent inhibitor of IAPs.Formula:C25H34N6O3SPurezza:97.18% - 99.32%Colore e forma:SolidPeso molecolare:498.64Birinapant
CAS:<p>Birinapant (TL32711) is a synthetic small molecule that is both a peptidomimetic of second mitochondrial-derived activator of caspases (SMAC) and inhibitor of</p>Formula:C42H56F2N8O6Purezza:97.08% - ≥95%Colore e forma:SolidPeso molecolare:806.94BV6
CAS:<p>BV6 is an antagonist of c-IAP1 and XIAP, members of the inhibitors of apoptosis (IAP) family.</p>Formula:C70H96N10O8Purezza:97.46% - 99.82%Colore e forma:SolidPeso molecolare:1205.57AZD5582 acetate (1258392-53-8 free base)
AZD5582 acetate is an inhibitor of IAPs, which binds to the BIR3 domains cIAP1, cIAP2, and XIAP with IC50s of 15, 21, and 15 nM, respectively.Formula:C60H82N8O10Purezza:97.76%Colore e forma:SolidPeso molecolare:1075.36
