IAP
Gli inibitori delle proteine inibitorie dell'apoptosi (IAP) sono composti che bloccano l'attività delle IAP, una famiglia di proteine che prevengono l'apoptosi inibendo le caspasi e altri componenti della macchina apoptotica. Gli inibitori delle IAP promuovono l'apoptosi nelle cellule tumorali neutralizzando questi segnali di sopravvivenza, rendendoli strumenti importanti nella ricerca sul cancro e nella terapia. Presso CymitQuimica, offriamo una gamma completa di inibitori delle IAP di alta qualità per supportare la tua ricerca in oncologia, apoptosi e sviluppo terapeutico.
Trovati 72 prodotti per "IAP".
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GDC-0152
CAS:GDC-0152 is a potent inhibitor of IAPs.Formula:C25H34N6O3SPurezza:97.18% - 99.32%Colore e forma:SolidPeso molecolare:498.64BV6
CAS:BV6 is an antagonist of c-IAP1 and XIAP, members of the inhibitors of apoptosis (IAP) family.Formula:C70H96N10O8Purezza:97.46% - 99.82%Colore e forma:SolidPeso molecolare:1205.57Ref: TM-T6428
1mg47,00€2mg62,00€5mg94,00€10mg137,00€1mL*10mM (DMSO)170,00€25mg270,00€50mg442,00€100mg707,00€Xevinapant
CAS:Xevinapant (Debio-1143) is a potent Smac mimetic and an antagonist of IAP, binding to XIAP-BIR3, cIAP1-BIR3 and cIAP2-BIR3.Formula:C32H43N5O4Purezza:98% - 99.94%Colore e forma:SolidPeso molecolare:561.71Ref: TM-T6763
1mg40,00€2mg54,00€5mg88,00€10mg124,00€1mL*10mM (DMSO)138,00€25mg260,00€50mg416,00€100mg647,00€200mg954,00€LCL161
CAS:LCL161 is a SMAC mimetic, an IAP antagonist with oral activity that inhibits XIAP and cIAP1. LCL161 has potential antitumor activity. Cost-effective and quality-assured.Formula:C26H33FN4O3SPurezza:99.13% - 99.87%Colore e forma:White SolidPeso molecolare:500.63Isolinderalactone
CAS:Isolinderalactone shows anti-inflammatory and anticancer capacity, and it exhibits moderate iNOS inhibitory activity, with the IC50 value of 0.30 uM.Formula:C15H16O3Purezza:98.76%Colore e forma:SolidPeso molecolare:244.29Embelin
CAS:Embelin (Embelic acid), isolated from the Japanese Ardisia herb, is an inhibitor of the X-linked inhibitor of apoptosis (IC50: 4.1 uM).Formula:C17H26O4Purezza:97.07% - 99.95%Colore e forma:Orange SolidPeso molecolare:294.39Polygalacin D
CAS:Polygalacin D shows anti- proliferation, anti-inflammary, and hepatoprotective activities, it can inhibit the expression of lipopolysaccharide (LPS)-inducedFormula:C57H92O27Purezza:98.95% - ≥98%Colore e forma:SolidPeso molecolare:1209.4CD47 Protein, Human, Recombinant (hFc & Avi), Biotinylated
CD47 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-Fc-Avi tag.Colore e forma:Lyophilized PowderPeso molecolare:60-70 KDa (reducing condition)CD47 Protein, Rhesus macaque, Recombinant (hFc)
CD47 Protein, Rhesus macaque, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag.Colore e forma:Lyophilized PowderPeso molecolare:60-90 KDa (reducing condition)Ref: TM-TMPJ-00613
5µg84,00€10µg120,00€20µg178,00€50µg351,00€100µg563,00€200µg888,00€500µg1.710,00€1mg2.457,00€CD47 Protein, Rhesus macaque, Recombinant (His & Flag)
CD47, also known as Integrin‑Associated Protein (IAP) and OA3, is a glycosylated atypical member of the immunoglobulin superfamily.Colore e forma:Lyophilized PowderPeso molecolare:33-55 KDa (reducing condition)Ref: TM-TMPJ-00614
5µg92,00€10µg149,00€20µg231,00€50µg439,00€100µg682,00€200µg1.063,00€500µg1.918,00€1mg2.890,00€A 410099.1
CAS:A 410099.1 is a BIRC (baculoviral IAP repeat-containing protein) inhibitor with EC50 values of 4.6, 9.2, 15.6, 19.9, and 93.9 nM for BIRC2/3/4/7/8.Formula:C27H41ClN4O3Purezza:99.30% - 99.53%Colore e forma:White SolidPeso molecolare:505.1NOC-5
CAS:NOC-5 is an NO donor that induces airway relaxation and concentration-dependently triggers 10 μM DAF-2 fluorescence.Formula:C6H16N4O2Purezza:98%Colore e forma:White SolidPeso molecolare:176.22MDM2/XIAP-IN-3
CAS:MDM2/XIAP-IN-3 (compound 3e), a dual inhibitor of MDM2/XIAP, diminishes MDM2 and XIAP protein levels while augmenting p53 expression, consequently suppressingFormula:C29H30N2O5SColore e forma:SolidPeso molecolare:518.62MX107
CAS:MX107 is a survivin inhibitor which induces degradation of XIAP and/or cIAP1, and suppresses genotoxic NF-kappaB activation.Formula:C24H28N2O2Colore e forma:SolidPeso molecolare:376.49T-3256336
CAS:T-3256336 is an oral IAP blocker targeting cIAP-1, cIAP-2, and XIAP.Formula:C31H45F2N5O5Purezza:98%Colore e forma:SolidPeso molecolare:605.72CUDC-427
CAS:CUDC-427 (GDC-0917) is an orally bioactive and pan antagonist of inhibitor of apoptosis proteins(IAPs). CUDC-427 can be used in research on cancers.Formula:C29H36N6O4SPurezza:99.92%Colore e forma:SolidPeso molecolare:564.7Anticancer agent 127
CAS:Anticancer agent 127 (142D6), an IAP inhibitor, covalently binds to the BIR3 domains of XIAP, cIAP1, and cIAP2, with IC50 values of 12 nM, 14 nM, and 9 nM,Formula:C26H37FN4O6SPurezza:98%Colore e forma:SolidPeso molecolare:552.66Anticancer agent 128
CAS:Anticancer agent 128 (compound 1) is an IAP inhibitor that covalently binds to the BIR3 domains of XIAP, cIAP1, and cIAP2, exhibiting IC50 values of 24.9 nM, 19Formula:C26H38N4O4Purezza:98%Colore e forma:SolidPeso molecolare:470.6XIAP/cIAP1 antagonist-1
Potent oral XIAP/cIAP1 inhibitor with EC50s: XIAP 5.1 nM, cIAP1 0.32 nM; curbs tumor growth in vivo.Colore e forma:SolidXIAP antagonist 1
CAS:XIAP antagonist 1 (compound A4) is a specific XIAP inhibitor that promotes the degradation of XIAP through the ubiquitin-proteasome pathway [1].Formula:C23H25ClN4O3Colore e forma:SolidPeso molecolare:440.92XIAP degrader-1
XIAP degrader-1 is a small primary amine molecule that promotes the degradation of X-linked apoptosis inhibitory protein (XIAP).Formula:C34H45N5O4Colore e forma:SolidPeso molecolare:587.75XB2M54
CAS:XB2M54 is a selective XIAP antagonist that inhibits NOD2-mediated inflammatory signaling. It acts as an E3 ligase ligand and is utilized in the synthesis of PROTACERαDegrader-1.Formula:C29H31N5O4Peso molecolare:513.59
