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IAP

IAP

Gli inibitori delle proteine inibitorie dell'apoptosi (IAP) sono composti che bloccano l'attività delle IAP, una famiglia di proteine che prevengono l'apoptosi inibendo le caspasi e altri componenti della macchina apoptotica. Gli inibitori delle IAP promuovono l'apoptosi nelle cellule tumorali neutralizzando questi segnali di sopravvivenza, rendendoli strumenti importanti nella ricerca sul cancro e nella terapia. Presso CymitQuimica, offriamo una gamma completa di inibitori delle IAP di alta qualità per supportare la tua ricerca in oncologia, apoptosi e sviluppo terapeutico.

Trovati 67 prodotti di "IAP"

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  • Xevinapant
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    Xevinapant

    CAS:
    Xevinapant (Debio-1143) is a potent Smac mimetic and an antagonist of IAP, binding to XIAP-BIR3, cIAP1-BIR3 and cIAP2-BIR3.
    Formula:C32H43N5O4
    Purezza:98% - 99.94%
    Colore e forma:Solid
    Peso molecolare:561.71

    Ref: TM-T6763

  • ASTX660
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    ASTX660

    CAS:
    Tolinapant (ASTX660) is an orally bioavailable cIAP1/2 and XIAP antagonist.Cost-effective and quality-assured.
    Formula:C30H42FN5O3
    Purezza:98.33% - 99.85%
    Colore e forma:Solid
    Peso molecolare:539.68

    Ref: TM-TQ0029

  • LCL161
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    LCL161

    CAS:
    LCL161 is a SMAC mimetic, an IAP antagonist with oral activity that inhibits XIAP and cIAP1. LCL161 has potential antitumor activity. Cost-effective and quality-assured.
    Formula:C26H33FN4O3S
    Purezza:99.13% - 99.87%
    Colore e forma:Solid
    Peso molecolare:500.63

    Ref: TM-T2080

  • Isolinderalactone
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    Isolinderalactone

    CAS:
    Isolinderalactone shows anti-inflammatory and anticancer capacity, and it exhibits moderate iNOS inhibitory activity, with the IC50 value of 0.30 uM.
    Formula:C15H16O3
    Purezza:98.76%
    Colore e forma:Solid
    Peso molecolare:244.29

    Ref: TM-T8213

  • 4-Methylsalicylic acid
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    4-Methylsalicylic acid

    CAS:
    <p>4-Methylsalicylic acid is used to inhibit the medium chain acyl-CoA synthetase.</p>
    Formula:C8H8O3
    Purezza:99.64%
    Colore e forma:Solid Solid Crystalline
    Peso molecolare:152.15

    Ref: TM-T22225

  • SM-164
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    SM-164

    CAS:
    SM-164 binds to XIAP protein containing both the BIR2 and BIR3 domains (IC50: 1.39 nM). It acts as an extremely potent antagonist of XIAP.
    Formula:C62H84N14O6
    Purezza:98.53% - 99.92%
    Colore e forma:Solid
    Peso molecolare:1121.42

    Ref: TM-T12932L

  • MX69
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    MX69

    CAS:
    MX69 is the MDM2/XIAP inhibitor, blocking the MDM2 protein-XIAP RNA interaction, leading to MDM2 degradation.
    Formula:C27H26N2O4S
    Purezza:97.27% - 99.57%
    Colore e forma:Solid
    Peso molecolare:474.57

    Ref: TM-T3653

  • T-3256336
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    T-3256336

    CAS:
    T-3256336 is an oral IAP blocker targeting cIAP-1, cIAP-2, and XIAP.
    Formula:C31H45F2N5O5
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:605.72

    Ref: TM-T26246

  • MX107
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    MX107

    CAS:
    MX107 is a survivin inhibitor which induces degradation of XIAP and/or cIAP1, and suppresses genotoxic NF-kappaB activation.
    Formula:C24H28N2O2
    Colore e forma:Solid
    Peso molecolare:376.49

    Ref: TM-T69845

  • NOC-5
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    NOC-5

    CAS:
    NOC-5 is an NO donor that induces airway relaxation and concentration-dependently triggers 10 μM DAF-2 fluorescence.
    Formula:C6H16N4O2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:176.22

    Ref: TM-T35969

  • MDM2/XIAP-IN-3
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    MDM2/XIAP-IN-3

    CAS:
    MDM2/XIAP-IN-3 (compound 3e), a dual inhibitor of MDM2/XIAP, diminishes MDM2 and XIAP protein levels while augmenting p53 expression, consequently suppressing
    Formula:C29H30N2O5S
    Colore e forma:Solid
    Peso molecolare:518.62

    Ref: TM-T79483

  • A 410099.1
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    A 410099.1

    CAS:
    A 410099.1 is a BIRC (baculoviral IAP repeat-containing protein) inhibitor with EC50 values of 4.6, 9.2, 15.6, 19.9, and 93.9 nM for BIRC2/3/4/7/8.
    Formula:C27H41ClN4O3
    Purezza:99.30%
    Colore e forma:Solid
    Peso molecolare:505.1

    Ref: TM-T36890

  • CUDC-427
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    CUDC-427

    CAS:
    CUDC-427 (GDC-0917) is an orally bioactive and pan antagonist of inhibitor of apoptosis proteins(IAPs). CUDC-427 can be used in research on cancers.
    Formula:C29H36N6O4S
    Purezza:99.92%
    Colore e forma:Solid
    Peso molecolare:564.7

    Ref: TM-T15018

  • Anticancer agent 127
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    Anticancer agent 127

    CAS:
    <p>Anticancer agent 127 (142D6), an IAP inhibitor, covalently binds to the BIR3 domains of XIAP, cIAP1, and cIAP2, with IC50 values of 12 nM, 14 nM, and 9 nM,</p>
    Formula:C26H37FN4O6S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:552.66

    Ref: TM-T79247

  • Anticancer agent 128
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    Anticancer agent 128

    CAS:
    Anticancer agent 128 (compound 1) is an IAP inhibitor that covalently binds to the BIR3 domains of XIAP, cIAP1, and cIAP2, exhibiting IC50 values of 24.9 nM, 19
    Formula:C26H38N4O4
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:470.6

    Ref: TM-T79248

  • Logo CymitQuimica
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    XIAP/cIAP1 antagonist-1

    <p>Potent oral XIAP/cIAP1 inhibitor with EC50s: XIAP 5.1 nM, cIAP1 0.32 nM; curbs tumor growth in vivo.</p>
    Colore e forma:Solid

    Ref: TM-T64302

  • Logo CymitQuimica
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    XIAP degrader-1

    XIAP degrader-1 is a small primary amine molecule that promotes the degradation of X-linked apoptosis inhibitory protein (XIAP).
    Formula:C34H45N5O4
    Colore e forma:Solid
    Peso molecolare:587.75

    Ref: TM-T64161