IAP
Gli inibitori delle proteine inibitorie dell'apoptosi (IAP) sono composti che bloccano l'attività delle IAP, una famiglia di proteine che prevengono l'apoptosi inibendo le caspasi e altri componenti della macchina apoptotica. Gli inibitori delle IAP promuovono l'apoptosi nelle cellule tumorali neutralizzando questi segnali di sopravvivenza, rendendoli strumenti importanti nella ricerca sul cancro e nella terapia. Presso CymitQuimica, offriamo una gamma completa di inibitori delle IAP di alta qualità per supportare la tua ricerca in oncologia, apoptosi e sviluppo terapeutico.
Trovati 67 prodotti di "IAP"
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CD47 Protein, Mouse, Recombinant (hFc)
CD47 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.Colore e forma:Lyophilized PowderPeso molecolare:40.6 kDa (predicted)CD47 Protein, Human, Recombinant
CD47 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 14.5 kDa and the accession number is Q08722-3.Purezza:97.8%Colore e forma:Lyophilized PowderPeso molecolare:14.5 kDa (predicted); 35 kDa (reducing condition, due to glycosylation)Alkaline phosphatase/ALPI Protein, Human, Recombinant (His)
Alkaline phosphatase Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Purezza:98.4%Colore e forma:Lyophilized PowderPeso molecolare:54 kDa (predicted); 66 kDa (reducing condition, due to glycosylation)CD47 Protein, Mouse, Recombinant (rFc)
CD47 Protein, Mouse, Recombinant (rFc) is expressed in HEK293 mammalian cells with rFc tag.Colore e forma:Lyophilized PowderPeso molecolare:39.9 kDa (predicted)Embelin
CAS:Embelin (Embelic acid), isolated from the Japanese Ardisia herb, is an inhibitor of the X-linked inhibitor of apoptosis (IC50: 4.1 uM).Formula:C17H26O4Purezza:97.07% - 99.88%Colore e forma:SolidPeso molecolare:294.39Polygalacin D
CAS:Polygalacin D shows anti- proliferation, anti-inflammary, and hepatoprotective activities, it can inhibit the expression of lipopolysaccharide (LPS)-inducedFormula:C57H92O27Purezza:98.95% - ≥98%Colore e forma:SolidPeso molecolare:1209.4GDC-0152
CAS:GDC-0152 is a potent inhibitor of IAPs.Formula:C25H34N6O3SPurezza:97.18% - 99.32%Colore e forma:SolidPeso molecolare:498.64Birinapant
CAS:<p>Birinapant (TL32711) is a synthetic small molecule that is both a peptidomimetic of second mitochondrial-derived activator of caspases (SMAC) and inhibitor of</p>Formula:C42H56F2N8O6Purezza:97.08% - ≥95%Colore e forma:SolidPeso molecolare:806.94BV6
CAS:<p>BV6 is an antagonist of c-IAP1 and XIAP, members of the inhibitors of apoptosis (IAP) family.</p>Formula:C70H96N10O8Purezza:97.46% - 99.82%Colore e forma:SolidPeso molecolare:1205.57AZD5582 acetate (1258392-53-8 free base)
AZD5582 acetate is an inhibitor of IAPs, which binds to the BIR3 domains cIAP1, cIAP2, and XIAP with IC50s of 15, 21, and 15 nM, respectively.Formula:C60H82N8O10Purezza:97.76%Colore e forma:SolidPeso molecolare:1075.36Xevinapant
CAS:Xevinapant (Debio-1143) is a potent Smac mimetic and an antagonist of IAP, binding to XIAP-BIR3, cIAP1-BIR3 and cIAP2-BIR3.Formula:C32H43N5O4Purezza:98% - 99.94%Colore e forma:SolidPeso molecolare:561.71ASTX660
CAS:Tolinapant (ASTX660) is an orally bioavailable cIAP1/2 and XIAP antagonist.Cost-effective and quality-assured.Formula:C30H42FN5O3Purezza:98.33% - 99.85%Colore e forma:SolidPeso molecolare:539.68LCL161
CAS:LCL161 is a SMAC mimetic, an IAP antagonist with oral activity that inhibits XIAP and cIAP1. LCL161 has potential antitumor activity. Cost-effective and quality-assured.Formula:C26H33FN4O3SPurezza:99.13% - 99.87%Colore e forma:SolidPeso molecolare:500.63Isolinderalactone
CAS:Isolinderalactone shows anti-inflammatory and anticancer capacity, and it exhibits moderate iNOS inhibitory activity, with the IC50 value of 0.30 uM.Formula:C15H16O3Purezza:98.76%Colore e forma:SolidPeso molecolare:244.294-Methylsalicylic acid
CAS:<p>4-Methylsalicylic acid is used to inhibit the medium chain acyl-CoA synthetase.</p>Formula:C8H8O3Purezza:99.64%Colore e forma:Solid Solid CrystallinePeso molecolare:152.15SM-164
CAS:SM-164 binds to XIAP protein containing both the BIR2 and BIR3 domains (IC50: 1.39 nM). It acts as an extremely potent antagonist of XIAP.Formula:C62H84N14O6Purezza:98.53% - 99.92%Colore e forma:SolidPeso molecolare:1121.42MX69
CAS:MX69 is the MDM2/XIAP inhibitor, blocking the MDM2 protein-XIAP RNA interaction, leading to MDM2 degradation.Formula:C27H26N2O4SPurezza:97.27% - 99.57%Colore e forma:SolidPeso molecolare:474.57T-3256336
CAS:T-3256336 is an oral IAP blocker targeting cIAP-1, cIAP-2, and XIAP.Formula:C31H45F2N5O5Purezza:98%Colore e forma:SolidPeso molecolare:605.72MX107
CAS:MX107 is a survivin inhibitor which induces degradation of XIAP and/or cIAP1, and suppresses genotoxic NF-kappaB activation.Formula:C24H28N2O2Colore e forma:SolidPeso molecolare:376.49NOC-5
CAS:NOC-5 is an NO donor that induces airway relaxation and concentration-dependently triggers 10 μM DAF-2 fluorescence.Formula:C6H16N4O2Purezza:98%Colore e forma:SolidPeso molecolare:176.22
