IAP
Gli inibitori delle proteine inibitorie dell'apoptosi (IAP) sono composti che bloccano l'attività delle IAP, una famiglia di proteine che prevengono l'apoptosi inibendo le caspasi e altri componenti della macchina apoptotica. Gli inibitori delle IAP promuovono l'apoptosi nelle cellule tumorali neutralizzando questi segnali di sopravvivenza, rendendoli strumenti importanti nella ricerca sul cancro e nella terapia. Presso CymitQuimica, offriamo una gamma completa di inibitori delle IAP di alta qualità per supportare la tua ricerca in oncologia, apoptosi e sviluppo terapeutico.
Trovati 71 prodotti per "IAP".
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CD47 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)
CD47 (Cluster of Differentiation 47) also known as integrin associated protein (IAP) is a transmembrane protein that in humans is encoded by the CD47 gene.Colore e forma:Lyophilized PowderPeso molecolare:15 kDa (predicted). Due to glycosylation, the protein migrates to 45-65 kDa based on Tris-Bis PAGE result.CD47 Protein, Mouse, Recombinant (hFc)
CD47 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.Colore e forma:White Lyophilized PowderPeso molecolare:40.6 kDa (predicted)CD47 Protein, Human, Recombinant
CD47 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 14.5 kDa and the accession number is Q08722-3.Purezza:97.8%Colore e forma:Lyophilized PowderPeso molecolare:14.5 kDa (predicted); 35 kDa (reducing condition, due to glycosylation)Alkaline phosphatase/ALPI Protein, Human, Recombinant (His)
Alkaline phosphatase Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Purezza:98.4%Colore e forma:White Lyophilized PowderPeso molecolare:54 kDa (predicted); 66 kDa (reducing condition, due to glycosylation)ASTX660
CAS:Tolinapant (ASTX660) is an orally bioavailable cIAP1/2 and XIAP antagonist.Cost-effective and quality-assured.Formula:C30H42FN5O3Purezza:98.33% - 99.85%Colore e forma:White SolidPeso molecolare:539.68Ref: TM-TQ0029
1mg79,00€5mg137,00€1mL*10mM (DMSO)163,00€10mg205,00€25mg409,00€50mg605,00€100mg860,00€Polygalacin D
CAS:Polygalacin D shows anti- proliferation, anti-inflammary, and hepatoprotective activities, it can inhibit the expression of lipopolysaccharide (LPS)-inducedFormula:C57H92O27Purezza:98.95% - ≥98%Colore e forma:SolidPeso molecolare:1209.4GDC-0152
CAS:GDC-0152 is a potent inhibitor of IAPs.Formula:C25H34N6O3SPurezza:97.18% - 99.32%Colore e forma:SolidPeso molecolare:498.64Birinapant
CAS:Birinapant (TL32711) is a synthetic small molecule that is both a peptidomimetic of second mitochondrial-derived activator of caspases (SMAC) and inhibitor ofFormula:C42H56F2N8O6Purezza:97.08% - ≥95%Colore e forma:SolidPeso molecolare:806.94Ref: TM-T6007
1mg34,00€2mg46,00€5mg70,00€1mL*10mM (DMSO)92,00€10mg109,00€25mg172,00€50mg250,00€100mg447,00€4-Methylsalicylic acid
CAS:4-Methylsalicylic acid is used to inhibit the medium chain acyl-CoA synthetase.Formula:C8H8O3Purezza:99.64%Colore e forma:White SolidPeso molecolare:152.15SM-164
CAS:SM-164 binds to XIAP protein containing both the BIR2 and BIR3 domains (IC50: 1.39 nM). It acts as an extremely potent antagonist of XIAP.Formula:C62H84N14O6Purezza:98.53% - 99.92%Colore e forma:SolidPeso molecolare:1121.42BV6
CAS:BV6 is an antagonist of c-IAP1 and XIAP, members of the inhibitors of apoptosis (IAP) family.Formula:C70H96N10O8Purezza:97.46% - 99.82%Colore e forma:SolidPeso molecolare:1205.57Ref: TM-T6428
1mg47,00€2mg62,00€5mg94,00€10mg137,00€1mL*10mM (DMSO)170,00€25mg270,00€50mg442,00€100mg707,00€MX69
CAS:MX69 is the MDM2/XIAP inhibitor, blocking the MDM2 protein-XIAP RNA interaction, leading to MDM2 degradation.Formula:C27H26N2O4SPurezza:97.27% - 99.57%Colore e forma:SolidPeso molecolare:474.57Ref: TM-T3653
2mg39,00€5mg58,00€1mL*10mM (DMSO)62,00€10mg92,00€25mg167,00€50mg260,00€100mg409,00€200mg590,00€Xevinapant
CAS:Xevinapant (Debio-1143) is a potent Smac mimetic and an antagonist of IAP, binding to XIAP-BIR3, cIAP1-BIR3 and cIAP2-BIR3.Formula:C32H43N5O4Purezza:98% - 99.94%Colore e forma:SolidPeso molecolare:561.71Ref: TM-T6763
1mg40,00€2mg54,00€5mg88,00€10mg124,00€1mL*10mM (DMSO)138,00€25mg260,00€50mg416,00€100mg647,00€200mg954,00€AZD5582 acetate (1258392-53-8 free base)
AZD5582 acetate is an inhibitor of IAPs, which binds to the BIR3 domains cIAP1, cIAP2, and XIAP with IC50s of 15, 21, and 15 nM, respectively.Formula:C60H82N8O10Purezza:97.76%Colore e forma:White SolidPeso molecolare:1075.36LCL161
CAS:LCL161 is a SMAC mimetic, an IAP antagonist with oral activity that inhibits XIAP and cIAP1. LCL161 has potential antitumor activity. Cost-effective and quality-assured.Formula:C26H33FN4O3SPurezza:99.13% - 99.87%Colore e forma:White SolidPeso molecolare:500.63Isolinderalactone
CAS:Isolinderalactone shows anti-inflammatory and anticancer capacity, and it exhibits moderate iNOS inhibitory activity, with the IC50 value of 0.30 uM.Formula:C15H16O3Purezza:98.76%Colore e forma:SolidPeso molecolare:244.29Embelin
CAS:Embelin (Embelic acid), isolated from the Japanese Ardisia herb, is an inhibitor of the X-linked inhibitor of apoptosis (IC50: 4.1 uM).Formula:C17H26O4Purezza:97.07% - 99.95%Colore e forma:Orange SolidPeso molecolare:294.39CD47 Protein, Rhesus macaque, Recombinant (His & Flag)
CD47, also known as Integrin‑Associated Protein (IAP) and OA3, is a glycosylated atypical member of the immunoglobulin superfamily.Colore e forma:Lyophilized PowderPeso molecolare:33-55 KDa (reducing condition)Ref: TM-TMPJ-00614
5µg92,00€10µg149,00€20µg231,00€50µg439,00€100µg682,00€200µg1.063,00€500µg1.918,00€1mg2.890,00€CD47 Protein, Rhesus macaque, Recombinant (hFc)
CD47 Protein, Rhesus macaque, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag.Colore e forma:Lyophilized PowderPeso molecolare:60-90 KDa (reducing condition)Ref: TM-TMPJ-00613
5µg84,00€10µg120,00€20µg178,00€50µg351,00€100µg563,00€200µg888,00€500µg1.710,00€1mg2.457,00€CD47 Protein, Human, Recombinant (hFc & Avi), Biotinylated
CD47 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-Fc-Avi tag.Colore e forma:Lyophilized PowderPeso molecolare:60-70 KDa (reducing condition)
