Chinesina
Gli inibitori delle chinesine prendono di mira le proteine motrici chinesine, responsabili del trasporto del carico cellulare lungo i microtubuli e che svolgono un ruolo chiave nella divisione cellulare, in particolare durante la mitosi. Le chinesine sono coinvolte nel movimento dei cromosomi e di altri organelli durante la divisione cellulare. Inibire le chinesine può interrompere questi processi, portando all'arresto del ciclo cellulare e alla possibile morte cellulare, rendendo questi inibitori preziosi nella ricerca sul cancro. Presso CymitQuimica, offriamo una gamma diversificata di inibitori delle chinesine di alta qualità per supportare la tua ricerca in biologia cellulare, mitosi e terapia del cancro.
Trovati 86 prodotti di "Chinesina"
Ordinare per
Purezza (%)
0
100
|
0
|
50
|
90
|
95
|
100
S-trityl-L-Cysteine
CAS:S-trityl-L-Cysteine is a potent inhibitor of human mitotic kinesin Eg5Formula:C22H21NO2SPurezza:97.02%Colore e forma:Almost White To Light Yellow Granular PowderPeso molecolare:363.47Empesertib
CAS:Empesertib (BAY 1161909) is an orally bioavailable and selective inhibitor Mps1(IC50 < 1 nM), with potential antineoplastic activity.Formula:C29H26FN5O4SPurezza:97.45% - 99.4%Colore e forma:SolidPeso molecolare:559.61Mps1-IN-2
CAS:Mps1-IN-2 is a potent, selective and ATP-competitive dual Mps1/Plk1 inhibitor.Formula:C26H36N6O3Purezza:96.24% - 99.75%Colore e forma:SolidPeso molecolare:480.6BAY1217389
CAS:BAY 1217389 is an effective and selective inhibitor of the monopolar spindle 1 (MPS1) kinase (IC50<10 nM).Formula:C27H24F5N5O3Purezza:98.14% - 99.42%Colore e forma:SolidPeso molecolare:561.5Mps1-IN-1
CAS:<p>Mps1-IN-1 is a potent, selective and ATP-competitive inhibitor of Mps1 kinase (IC50 : 367 nM )</p>Formula:C28H33N5O4SPurezza:98.33%Colore e forma:SolidPeso molecolare:535.66CFI-400936
CAS:CFI-400936: potent TTK inhibitor (IC50=3.6nM), potential anticancer, active in cell assays, selective vs. human kinases.Formula:C25H27N5O3SColore e forma:SolidPeso molecolare:477.58PF-2771
CAS:PF-2771: potent CENP-E inhibitor, IC50 of 16.1 nM, used in cancer treatment.Formula:C29H36ClN5O4Purezza:98%Colore e forma:SolidPeso molecolare:554.08TC-Mps1-12
CAS:<p>TC-Mps1-12 is an effective and selective inhibitor of monopolar spindle 1 (IC50: 6.4 nM) .</p>Formula:C17H20N6OPurezza:98%Colore e forma:SolidPeso molecolare:324.38(R)-Filanesib
CAS:(R)-Filanesib is the R-enantiomer of ARRY-520. (R)-Filanesib is a synthetic kinesin spindle protein (KSP) inhibitor (IC50: 6 nM).Formula:C20H22F2N4O2SColore e forma:SolidPeso molecolare:420.48Litronesib Racemate
CAS:Litronesib is a selective, allosteric inhibitor of kinesin Eg5.Litronesib (Racemate) is the racemate of litronesib.Formula:C23H37N5O4S2Colore e forma:SolidPeso molecolare:511.7Eg5 Inhibitor V, trans-24
CAS:Eg5 Inhibitor V, trans-24 is a specific and potent Eg5 inhibitor that can be used in cancer research with an IC50 value of 0.65 uM.Formula:C26H21N3O3Purezza:99.75%Colore e forma:SolidPeso molecolare:423.46Mps-BAY2b
CAS:Mps-BAY2b is a novel MPS1 inhibitor.Formula:C20H23N5OColore e forma:SolidPeso molecolare:349.43Mps1-IN-4
CAS:Mps1-IN-4 is a compound that selectively inhibits Monopolar spindle 1 (Mps1), exhibiting antiproliferative properties useful in cancer research.Formula:C26H31F3N6O2Colore e forma:SolidPeso molecolare:516.56Syntelin
CAS:Syntelin: a selective CENP-E inhibitor with an IC50 of 160 nM; distinct from GSK923295, effective on resistant mutants.Formula:C21H20N6O2S3Colore e forma:SolidPeso molecolare:484.62EMD534085
CAS:EMD534085 is an effective and selective mitotic kinesin-5 inhibitor (IC50: 8 nM).Formula:C25H31F3N4O2Purezza:98%Colore e forma:SolidPeso molecolare:476.53HR22C16
CAS:HR22C16 is an effective, selective, and cell-permeable mitotic kinesin Eg5 inhibitor.Formula:C23H23N3O3Colore e forma:SolidPeso molecolare:389.45KIF18A-IN-4
CAS:KIF18A-IN-4: Non-competitive KIF18A inhibitor, IC50 6.16 μM, targets mitotic kinesins/kinases, anti-tumor.Formula:C22H27N3O3SColore e forma:SolidPeso molecolare:413.53CK0106023
CAS:CK0106023, a KSP inhibitor, shows strong antitumor effects in mice, outperforming paclitaxel, and induces monopolar spindles.Formula:C30H32BrClN4O2Colore e forma:SolidPeso molecolare:595.96AM-5308
CAS:AM-5308 is a kinesin KIF18A inhibitor that can be used to study cancer.Formula:C26H35N5O5SPurezza:98.06% - 99.58%Colore e forma:SolidPeso molecolare:529.65SR31527
CAS:SR31527 chloride: potent KIFC1 inhibitor (IC50 6.6 µM), moderately impairs cell viability & colony growth.Formula:C15H14ClN3OSPurezza:98%Colore e forma:SolidPeso molecolare:319.81
