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Integrina

Integrina

Gli inibitori delle integrine prendono di mira le integrine, una famiglia di recettori di superficie cellulare che svolgono un ruolo cruciale nell'adesione cellulare, nella migrazione e nella trasduzione del segnale. Le integrine sono coinvolte nella regolazione del ciclo cellulare, in particolare in processi come la divisione e la differenziazione cellulare. L'inibizione delle integrine può interrompere questi processi, portando all'arresto del ciclo cellulare e all'apoptosi, rendendo questi inibitori strumenti preziosi nella ricerca sul cancro e nello studio delle metastasi. Presso CymitQuimica, offriamo una vasta gamma di inibitori delle integrine di alta qualità per supportare la tua ricerca sulla regolazione del ciclo cellulare, la biologia del cancro e lo sviluppo terapeutico.

Trovati 256 prodotti di "Integrina"

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  • Sibrafiban
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    Sibrafiban

    CAS:
    Sibrafiban (RO 48-3657), an oral, nonpeptide prodrug, inhibits platelet aggregation as a selective IIb/IIIa antagonist.
    Formula:C20H28N4O6
    Colore e forma:Solid
    Peso molecolare:420.46

    Ref: TM-T28775

  • GSK-3008348
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    GSK-3008348

    CAS:
    GSK-3008348 is an antagonist of integrin alpha(v)beta6.
    Formula:C29H37N5O2
    Purezza:99.547%
    Colore e forma:Solid
    Peso molecolare:487.64

    Ref: TM-T24108

  • RUC-1
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    RUC-1

    CAS:
    RUC-1 is an αIIbβ3-selective ADP-induced platelet aggregation inhibitor.
    Formula:C11H15N5OS
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:265.33

    Ref: TM-T24745

  • Valategrast
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    Valategrast

    CAS:
    Valategrast: potent, oral dual α4β1/α4β7 integrin antagonist, may treat COPD and asthma.
    Formula:C30H32Cl3N3O4
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:604.95

    Ref: TM-T13277

  • Integrin-IN-2
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    Integrin-IN-2

    CAS:
    Integrin-IN-2, an oral αv integrin blocker, enhances αvβ6/3/5/8 affinities with pIC50s: 7.8/8.4/8.4/7.4.
    Formula:C27H30N4O3
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:458.55

    Ref: TM-T11663

  • IS-741 calcium
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    IS-741 calcium

    CAS:
    IS-741 calcium is a phospholipase A2 inhibitor.
    Formula:C30H38CaF6N6O6S2
    Colore e forma:Solid
    Peso molecolare:796.86

    Ref: TM-T70742

  • BMS-688521
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    BMS-688521

    CAS:
    BMS-688521 is an LFA-1/ICAM interaction inhibitor, a small molecule antagonist of LFA-1 with potential anti-inflammatory activity.
    Formula:C26H19Cl2N5O4
    Purezza:98.87%
    Colore e forma:Solid
    Peso molecolare:536.37

    Ref: TM-T14676

  • CLT-28643
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    CLT-28643

    CAS:
    CLT-28643 is a specific α5β1-Integrin inhibitor that prevents fibrosis in GFS, inhibits tumor growth and angiogenesis, suppresses fibrosis and inflammation.
    Formula:C19H17N3O4
    Purezza:99.89%
    Colore e forma:Solid
    Peso molecolare:351.36

    Ref: TM-T71368

  • Integrin modulator 1
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    Integrin modulator 1

    CAS:
    Integrin modulator 1 is a selective α4β1 integrin agonist (IC50 9.8 nM) that enhances adhesion with EC50 12.9 nM, aiding integrin-dependent studies.
    Formula:C13H14N2O4
    Purezza:99.61%
    Colore e forma:Solid
    Peso molecolare:262.26

    Ref: TM-T36291

  • Valategrast hydrochloride
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    Valategrast hydrochloride

    CAS:
    Valategrast hydrochloride (R411), a dual antagonist of integrin α4β1 (VLA-4), is used for the potential treatment of asthma.
    Formula:C30H33Cl4N3O4
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:641.41

    Ref: TM-T29089

  • TCS 2314
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    TCS 2314

    CAS:
    TCS 2314 is an orally active and selective very late antigen-4 antagonist (IC50: 4.4 nM).
    Formula:C28H34N4O6
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:522.59

    Ref: TM-T17020

  • Zaurategrast ethyl ester sulfate
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    Zaurategrast ethyl ester sulfate

    CAS:
    Zaurategrast ethyl ester sulfate is a α4β1/α4β7 integrin antagonist, and used for the treatment of inflammatory and autoimmune disorders.
    Formula:C56H60Br2N8O10S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:1197.01

    Ref: TM-T13388

  • Zaurategrast ethyl ester
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    Zaurategrast ethyl ester

    CAS:
    Zaurategrast ethyl ester, an α4β1/α4β7 integrin antagonist prodrug of CT7758, treats inflammatory/autoimmune conditions.
    Formula:C28H29BrN4O3
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:549.46

    Ref: TM-T13388L

  • IMB-10
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    IMB-10

    CAS:
    IMB-10 is an alphaMbeta2 integrin modulator, inhibiting leukocyte migration and recruitment in vitro and in vivo.
    Formula:C19H15NOS2
    Colore e forma:Solid
    Peso molecolare:337.46

    Ref: TM-T71869

  • Firategrast
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    Firategrast

    CAS:
    Firategrast (SB 683699) is an orally active and specific α4β1/α4β7 integrin antagonist.Firategrast reduces the transport of lymphocytes into the central nervous
    Formula:C27H27F2NO6
    Purezza:99.67%
    Colore e forma:Solid
    Peso molecolare:499.5

    Ref: TM-TQ0291

  • Elarofiban
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    Elarofiban

    CAS:
    Elarofiban(RWJ-53308) is a novel and orally active GPIIb/IIIa antagonist.
    Formula:C22H32N4O4
    Purezza:98.76%
    Colore e forma:Solid
    Peso molecolare:416.51

    Ref: TM-T27250

  • αvβ1 integrin-IN-2
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    αvβ1 integrin-IN-2

    CAS:
    <p>αvβ1 integrin-IN-2 (compound 32) is a potent inhibitor of ανβ1 and α5β1 integrins, exhibiting IC50 values of 0.9 nM and 33 nM, respectively.</p>
    Formula:C29H38N4O4
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:506.64

    Ref: TM-T79792

  • Bexotegrast HCl
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    Bexotegrast HCl

    CAS:
    Bexotegrast (PLN-74809) inhibits αVβ1/αVβ6 integrins, preventing TGF-β1 activation to treat IPF and PSC.
    Formula:C27H38Cl2N6O3
    Colore e forma:Solid
    Peso molecolare:565.54

    Ref: TM-T69517

  • 3-Hydroxyxanthone
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    3-Hydroxyxanthone

    CAS:
    3-Hydroxyxanthone (3-Hydroxy-xanthen-9-one), a xanthone derivative, exhibits inhibitory effects on NADPH-catalyzed lipid peroxidation in human umbilical vein
    Formula:C13H8O3
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:212.2

    Ref: TM-T78548

  • ICAM-1-IN-1
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    ICAM-1-IN-1

    CAS:
    <p>ICAM-1-IN-1 is a potent and selective E-selectin(IC50 = 7 nM) and ICAM-1(IC50 = 5 nM) inhibitor.</p>
    Formula:C15H11BrN2O2S
    Purezza:99.67%
    Colore e forma:Solid
    Peso molecolare:363.23

    Ref: TM-T13147