Integrina
Gli inibitori delle integrine prendono di mira le integrine, una famiglia di recettori di superficie cellulare che svolgono un ruolo cruciale nell'adesione cellulare, nella migrazione e nella trasduzione del segnale. Le integrine sono coinvolte nella regolazione del ciclo cellulare, in particolare in processi come la divisione e la differenziazione cellulare. L'inibizione delle integrine può interrompere questi processi, portando all'arresto del ciclo cellulare e all'apoptosi, rendendo questi inibitori strumenti preziosi nella ricerca sul cancro e nello studio delle metastasi. Presso CymitQuimica, offriamo una vasta gamma di inibitori delle integrine di alta qualità per supportare la tua ricerca sulla regolazione del ciclo cellulare, la biologia del cancro e lo sviluppo terapeutico.
Trovati 278 prodotti di "Integrina"
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αvβ1 integrin-IN-2
CAS:αvβ1 integrin-IN-2 (compound 32) is a potent inhibitor of ανβ1 and α5β1 integrins, exhibiting IC50 values of 0.9 nM and 33 nM, respectively.Formula:C29H38N4O4Purezza:98%Colore e forma:SolidPeso molecolare:506.64Lotrafiban hydrochloride
CAS:Lotrafiban hydrochloride is an platelet glycoprotein IIb/IIIa blocker with oral activity.Formula:C23H33ClN4O4Colore e forma:SolidPeso molecolare:464.99Bexotegrast HCl
CAS:Bexotegrast (PLN-74809) inhibits αVβ1/αVβ6 integrins, preventing TGF-β1 activation to treat IPF and PSC.Formula:C27H38Cl2N6O3Colore e forma:SolidPeso molecolare:565.54BI-1950
CAS:BI-1950: potent inhibitor of LFA-1, key in immune function and drug target.Formula:C32H26Cl2FN7O3Purezza:98%Colore e forma:SolidPeso molecolare:646.5Gly-Arg-Gly-Asp-Ser TFA
CAS:Gly-Arg-Gly-Asp-Ser (TFA), osteopontin domain, binds αvβ3 and αvβ5 integrins; IC50s: ~5 μM, ~6.5 μM.Formula:C19H31F3N8O11Colore e forma:SolidPeso molecolare:604.49Lotrafiban
CAS:Lotrafiban: Oral GP IIb/IIIa inhibitor for treating coronary and cerebrovascular disease.Formula:C23H32N4O4Colore e forma:SolidPeso molecolare:428.52L 738167
CAS:L 738167 is a potent antagonist of the long-acting fibrinogen receptor.Formula:C25H34N6O6SColore e forma:SolidPeso molecolare:546.64ICAM-1-IN-1
CAS:ICAM-1-IN-1 is a potent and selective E-selectin(IC50 = 7 nM) and ICAM-1(IC50 = 5 nM) inhibitor.Formula:C15H11BrN2O2SPurezza:99.67%Colore e forma:SolidPeso molecolare:363.23Ref: TM-T13147
1mg175,00€5mg371,00€1mL*10mM (DMSO)409,00€10mg557,00€25mg887,00€50mg1.198,00€100mg1.611,00€500mg3.232,00€SC-52012
CAS:SC-52012 is a novel and potent fibrinogen receptor antagonist, an RGD mimetic, which inhibits platelet aggregation.Formula:C25H30N4O6Purezza:97.20%Colore e forma:SolidPeso molecolare:482.53Lamifiban
CAS:Lamifiban is a nonpeptide glycoprotein IIb/IIIa antagonist. It prevents platelet loss during experimental cardiopulmonary bypass.Formula:C24H28N4O6Purezza:98%Colore e forma:SolidPeso molecolare:468.5Zaurategrast
CAS:Zaurategrast (CDP323) is an oral α4-integrin antagonist that blocks VCAM-1 interactions and is used to study immune cell trafficking.Formula:C26H25BrN4O3Purezza:98%Colore e forma:SolidPeso molecolare:521.41SB-267268
CAS:SB-267268: αvβ3 inhibitor (IC50: 0.68 nM human, 0.29 nM mouse), blocks αvβ3/αvβ5 integrins (Ki: 0.9 nM human, 0.5 nM monkey αvβ3, 0.7 nM human αvβ5).Formula:C22H24F3N3O4Purezza:98%Colore e forma:SolidPeso molecolare:451.44Carotegrast
CAS:Carotegrast, an orally available α4 integrin receptor inhibitor, has anti-inflammatories activities.Formula:C27H24Cl2N4O5Colore e forma:SolidPeso molecolare:555.41Tirofiban HCl
CAS:Tirofiban HCl is an antagonist of platelet glycoprotein-IIb/IIIa receptor.
Formula:C22H37ClN2O5SPurezza:98%Colore e forma:SolidPeso molecolare:477.06αvβ6 integrin inhibitor 2
CAS:αvβ6 Integrin Inhibitor 2 is a potent inhibitor of αvβ6 integrin, demonstrating an inhibition concentration (IC50) of 96.5 nM.Formula:C21H30N4O3Purezza:98%Colore e forma:SolidPeso molecolare:386.49αvβ1 integrin-IN-1
CAS:αvβ1 integrin-IN-1 is a potent and selective inhibitor of αvβ1 integrin (IC50 of 0.63 nM) with antifibrotic effects.Formula:C26H34N6O6SPurezza:99.39% - 99.69%Colore e forma:SolidPeso molecolare:558.65Ref: TM-T13473
1mg109,00€5mg260,00€1mL*10mM (DMSO)319,00€10mg409,00€25mg660,00€50mg888,00€100mg1.224,00€200mg1.648,00€Roxifiban acetate
CAS:Roxifiban acetate（DMP 754 acetate） is a potent GP IIb / IIIa antagonist that exhibits antiplatelet aggregation activity via immune mediation and can be used inFormula:C23H33N5O8Purezza:97.91% - 98.36%Colore e forma:SolidPeso molecolare:507.54Fradafiban
CAS:Fradafiban binds to the human platelet GP IIb/IIIa complex with a Kd value of 148 nM. Fradafiban is a non-polypeptide platelet glycoprotein IIb/IIIa antagonist.Formula:C20H21N3O4Purezza:98%Colore e forma:SolidPeso molecolare:367.40SF0166
CAS:SF0166: potent αvβ3 antagonist, IC50: 0.6 nM. Blocks cell adhesion, IC50: 7.6 pM-76 nM. Reduces neovascularization in mice.Formula:C23H27F2N5O4Colore e forma:SolidPeso molecolare:475.49Zalunfiban dihydrochloride
Zalunfiban (RUC-4) is a potent αIIbβ3 platelet antagonist, IC50 45 nM, used in myocardial infarction research.Formula:C16H20Cl2N8O2SColore e forma:SolidPeso molecolare:459.35OPN expression inhibitor 1
CAS:OPN expression inhibitor 1 is an osteopontin expression inhibitor used in the study of breast cancer metastasis.Formula:C25H33N3O5Purezza:99.78%Colore e forma:SolidPeso molecolare:455.55Ref: TM-T62820
1mg126,00€5mg258,00€1mL*10mM (DMSO)259,00€10mg385,00€25mg695,00€50mg1.009,00€100mg1.314,00€Des-ethyl-carafiban
CAS:Des-ethyl-carafiban (Compound 44) is an antagonist of the fibrinogen receptor, effectively inhibiting platelet aggregation induced by various agonists. It is useful for research in thrombotic diseases.Formula:C22H23N5O5Colore e forma:SolidPeso molecolare:437.448α5β1 integrin agonist-1
CAS:α5β1 integrin agonist-1 is an α5β1 integrin agonist that selectively delivers 5-FU to tumour cells and induces tumour cell death.Formula:C24H26FN5O9Colore e forma:SolidPeso molecolare:547.496-B345TTQ
CAS:6-B345TTQ is an α4 integrin inhibitor that can impede the interaction between α4 and Leupaxin. This compound is applicable for studies focused on inflammation research.Formula:C22H20BrNO4Colore e forma:SolidPeso molecolare:442.303GR 83895
CAS:GR 83895 is an antagonist of prototype fibrinogen receptor.Formula:C29H39N9O8SPurezza:98%Colore e forma:SolidPeso molecolare:673.74L 734217
CAS:L 734217 is an antagonist of the fibrinogen receptor.Formula:C18H31N3O4Purezza:98%Colore e forma:SolidPeso molecolare:353.46GSK3335103
CAS:GSK3335103 is a non-peptide, orally active inhibitor of αvβ6 integrin (pIC50=8), employed in the study of pulmonary fibrosis.Formula:C27H36FN3O4Colore e forma:SolidPeso molecolare:485.59SR121566A
CAS:SR121566A is a novel non-peptide antagonist of Glycoprotein IIb/IIIa (GP IIb-IIIa).Formula:C20H25N5O4SPurezza:98%Colore e forma:SolidPeso molecolare:431.51
