Integrina
Gli inibitori delle integrine prendono di mira le integrine, una famiglia di recettori di superficie cellulare che svolgono un ruolo cruciale nell'adesione cellulare, nella migrazione e nella trasduzione del segnale. Le integrine sono coinvolte nella regolazione del ciclo cellulare, in particolare in processi come la divisione e la differenziazione cellulare. L'inibizione delle integrine può interrompere questi processi, portando all'arresto del ciclo cellulare e all'apoptosi, rendendo questi inibitori strumenti preziosi nella ricerca sul cancro e nello studio delle metastasi. Presso CymitQuimica, offriamo una vasta gamma di inibitori delle integrine di alta qualità per supportare la tua ricerca sulla regolazione del ciclo cellulare, la biologia del cancro e lo sviluppo terapeutico.
Trovati 256 prodotti di "Integrina"
Ordinare per
Purezza (%)
0
100
|
0
|
50
|
90
|
95
|
100
E7820
CAS:<p>E7820 (ER68203-00) is an angiogenesis inhibitor by suppressing integrin a2 (a cell adhesion molecule expressed on endothelial cells).</p>Formula:C17H12N4O2SPurezza:98.31% - 99.11%Colore e forma:SolidPeso molecolare:336.37iRGD peptide
CAS:iRGD peptide: 9-amino acid cyclic compound (CRGDKGPDC), found through phage display in mice with tumors.Formula:C35H57N13O14S2Purezza:98.77%Colore e forma:SolidPeso molecolare:948.04Leukadherin-1
CAS:Leukadherin-1 boosts CD11b/CD18 adhesion, lowers leukocyte movement, cuts inflammation.Formula:C22H15NO4S2Purezza:98.49% - 98.93%Colore e forma:SolidPeso molecolare:421.49Cyclo(-RGDfK)
CAS:Cyclo(-RGDfK) is a selective and potent inhibitor of integrin αvβ3 with an IC50 value of 0.94 nM.Cost-effective and quality-assured.Formula:C27H41N9O7Purezza:95.29% - >99.99%Colore e forma:SolidPeso molecolare:603.67ILK-IN-2
CAS:<p>ILK-IN-2 (OSU-T315) is a novel potent, orally active ILK (integrin-linked kinase) inhibitor with IC50 of 0.6 μM.</p>Formula:C30H30F3N5OPurezza:99.30%Colore e forma:SolidPeso molecolare:533.59PND-1186
CAS:PND-1186 (VS-4718) is a reversible and specific FAK inhibitor (IC50: 1.5 nM).Formula:C25H26F3N5O3Purezza:99.14% - 99.75%Colore e forma:SolidPeso molecolare:501.5Bexotegrast
CAS:Bexotegrast (PLN-74809) is an αvβ6 and αvβ1 integrin inhibitor with antifibrotic properties for the study of idiopathic pulmonary fibrosis (IPF).Formula:C27H36N6O3Purezza:99.53%Colore e forma:SolidPeso molecolare:492.61RO0270608
CAS:RO0270608 is an α4β1/α4β7 integrin antagonist with anti-inflammatory activity for the study of allergic inflammatory responses.Formula:C24H19Cl3N2O4Purezza:98.26%Colore e forma:SolidPeso molecolare:505.78Vepsitamab
CAS:Vepsitamab (AMG 199), an anti-MUC17/CD3 BiTE, targets T cells and tumors for cell lysis and T cell activation.Colore e forma:LiquidCevostamab
CAS:Cevostamab (BFCR4350A, RG6160, RO7187797) is a humanized BsAb IgG1 targeting FcRH5 on MM cells and CD3 on T cells to enhance T-cell-mediated MM cell killing.Colore e forma:LiquidUbamatamab
CAS:Ubamatamab (REGN4018), a human bispecific antibody targeting Mucin 16 (MUC16) and CD3, exhibits potent antitumor activity [1].Colore e forma:LiquidTepoditamab
CAS:<p>Tepoditamab (MCLA-117) is a bispecific antibody targeting CLEC12A and CD3, inducing T cell lysis of AML cells.</p>Colore e forma:LiquidPacanalotamab
CAS:Pacanalotamab (AMG 420/BI-836909), a BiTE, directs T-cells to BCMA+ MM cells, causing lysis.Colore e forma:LiquidPavurutamab
CAS:Pavurutamab (AMG-701) is a bispecific T cell engager targeting CD3 and BCMA with extended half-life, designed to treat MM.Colore e forma:LiquidCaplacizumab
CAS:Caplacizumab (ALX-0681), a humanized anti-von Willebrand factor (vWF) nanobody, serves to impede vWF-mediated platelet adhesion, thereby averting additionalColore e forma:LiquidPasotuxizumab
CAS:Pasotuxizumab (BAY 2010112) is a BiTE that targets PSMA & CD3 with K D s 47.0 & 9.4 nM, for mCRPC research.Colore e forma:LiquidEnlimomab
CAS:<p>Enlimomab (BI-RR 0001), a mouse IgG2a antibody, blocks leukocyte binding to ICAM-1, reducing inflammation and used in stroke research.</p>Colore e forma:LiquidVatelizumab
CAS:Vatelizumab is a humanised monoclonal antibody targeting Integrin α2β1 ( VLA-2, CD49b), which enhances the frequency of regulatory T cells multiple sclerosis.Purezza:95%Colore e forma:LiquidAlnuctamab
CAS:Alnuctamab (EM901) is a humanized, asymmetric two-arm IgG T-cell engager (TCE) with potential applications in immunological research [1].Colore e forma:LiquidVonsetamig
CAS:Vonsetamig, a humanized immunoglobulin G4-kappa monoclonal antibody, targets both TNFRSF17 and CD3E. It serves as an antineoplastic agent.Colore e forma:LiquidAnti-Mouse CD3ε Antibody (145-2C11)
Anti-Mouse CD3ε Antibody (145-2C11) is an antibody inhibitor targeting CD3ε in Armenian hamsters, in TCR formation and in T lymphocyte activationPurezza:99%Colore e forma:Odour LiquidRovelizumab
CAS:Rovelizumab: humanized anti-CD11/CD18 antibody for MS, hemorrhagic shock, MI, and stroke research.Purezza:95% - 95%Colore e forma:LiquidFlotetuzumab
CAS:Flotetuzumab (MGD006/S80880) is a CD123/CD3 bispecific DART antibody, reactivating T-cells for AML treatment.Colore e forma:LiquidAnti-Mouse IL-1a Antibody (ALF-161)
Anti-Mouse IL-1a Antibody is an IgG1 subtype inhibitor specific to mouse IL-1a, derived from the Armenian Hamster.Purezza:98%Colore e forma:Odour LiquidVibecotamab
CAS:Vibecotamab, a bispecific antibody, targets CD123/CD3 for T-cell killing of tumors, promising for acute myeloid leukemia.Colore e forma:LiquidObrindatamab
CAS:Obrindatamab: a humanized bispecific antibody targeting B7-H3/CD3, enhances CTL-mediated cancer cell killing.Colore e forma:LiquidLinvoseltamab
CAS:Linvoseltamab, a bispecific antibody, targets both BCMA (TNFRSF17) and CD3 epsilon, demonstrating a favorable safety profile and promising efficacy in relapsed/Colore e forma:LiquidGresonitamab
CAS:Gresonitamab (AMG 910) is an HLE BiTE antibody targeting CD3+ T cells and CLDN18.2+ tumors, for adenocarcinoma research.Colore e forma:LiquidVoxalatamab
CAS:Voxalatamab (JNJ-63898081), an IgG4 bispecific antibody targeting PSMA and CD3, demonstrates anti-cancer efficacy in prostate cancer research [1].Colore e forma:LiquidAnti-Mouse TCR γ/δ Antibody (UC7-13D5)
Anti-Mouse TCR gamma/delta Antibody is a host Armenian Hamster-derived IgG class inhibitor targeting the mouse TCR gamma/delta receptor.Colore e forma:Odour LiquidOS-2966
OS-2966 is a humanised de-immunised monoclonal antibody that target Integrin b1/ITGB1/CD29, malignant gliomas, glioblastomas, and astrocytomas.Purezza:95%Colore e forma:Odour LiquidSB273005
CAS:SB273005 is a potent integrin inhibitor with Ki of 1.2 nM and 0.3 nM for αvβ3 receptor and αvβ5 receptor, respectively.Formula:C22H24F3N3O4Purezza:99.58%Colore e forma:SolidPeso molecolare:451.44Tirofiban
CAS:Tirofiban (L700462) (MK-383) is a selective palate GPIIb/IIIa antagonist which inhibits platelet aggregation with IC50 of 9 nM.Formula:C22H36N2O5SPurezza:99.83%Colore e forma:SolidPeso molecolare:440.6IS-741 potassium
CAS:IS-741 potassium is a phospholipase A2 inhibitor.Formula:C15H19F3KN3O3SColore e forma:SolidPeso molecolare:417.49UR-2922
CAS:UR-2922: Oral GPIIb/IIIa blocker with <1 nM affinity, slow 90 min k(off), no LIBS or prothrombotic effects.Formula:C25H25N7O6Purezza:98%Colore e forma:SolidPeso molecolare:519.51MK-0668 Mesylate
CAS:MK-0668 Mesylate is the mesylate form of MK-0668 that is a very potent and orally active very late antigen-4 antagonist.Formula:C32H34Cl2N6O9S2Colore e forma:SolidPeso molecolare:781.68BMS-587101
CAS:BMS-587101 is a small molecule antagonist of LFA-1, which can reduce inflammation and joint destruction in the mouse model of arthritis.Formula:C26H20Cl2N4O4SColore e forma:SolidPeso molecolare:555.43BOP sodium
CAS:BOP sodium salt is an inhibitor of alpha9beta1 and alpha4beta1 integrin.Formula:C25H29N3NaO7SColore e forma:SolidPeso molecolare:538.57L 703014
CAS:L 703014 is an antagonist of the fibrinogen receptor.Formula:C24H34N4O4Purezza:98%Colore e forma:SolidPeso molecolare:442.55Balamapimod
CAS:<p>Balamapimod is a reversible inhibitor of Ras/Raf/MEK. It also has a potential anti-tumor activity.</p>Formula:C30H32ClN7OSPurezza:98%Colore e forma:SolidPeso molecolare:574.14Zalunfiban
CAS:RUC-4 is an aIIb 3 antagonist. It is also used for prehospital therapy of myocardial infarction.Formula:C16H18N8O2SColore e forma:SolidPeso molecolare:386.43αvβ1 integrin-IN-1 TFA (1689540-62-2 free base)
αvβ1 integrin-IN-1 TFA is an effective and selective αvβ1 integrin inhibitor (IC50: 0.63 nM).Formula:C28H35F3N6O8SPurezza:98%Colore e forma:SolidPeso molecolare:672.67GR 144053 trihydrochloride
CAS:platelet fibrinogen receptor glycoprotein IIb/IIIa (GpIIb/IIIa) antagonistFormula:C18H30Cl3N5O2Purezza:98%Colore e forma:SolidPeso molecolare:454.82MK-0668
CAS:<p>MK-0668 is a very potent and orally active very late antigen-4 antagonist.</p>Formula:C31H30Cl2N6O6SColore e forma:SolidPeso molecolare:685.58Chrysotobibenzyl
CAS:Chrysotobibenzyl from Dendrobium pulchellum stems may trigger cell death in detached cells and hinder lung cancer growth.Formula:C19H24O5Colore e forma:SolidPeso molecolare:332.39Nexinhib20
CAS:Nexinhib20 is an inhibitor of exosome synthesis and transport with anti-inflammatory activity, inhibits RAB27A and neutral sphingomyelinase 2 (nSMase2) nsMase2.Formula:C15H16N4O3Purezza:99.89%Colore e forma:SolidPeso molecolare:300.31XVA143
CAS:XVA143, an α/β I-like allosteric antagonist, blocks LFA-1 adhesion and combats P. gingivalis in mice, preventing bone loss.Formula:C25H21Cl2N3O8Colore e forma:SolidPeso molecolare:562.36UR-3216
CAS:UR-3216 is a prodrug, selectively antagonizing GPIIb/IIIa receptors orally, with its active form, UR-2992, binding tightly to platelets.Formula:C27H29N7O7Purezza:98%Colore e forma:SolidPeso molecolare:563.56NSC47924
CAS:NSC47924 is a laminin receptor (LR) inhibitor.Formula:C18H17NO2Purezza:98%Colore e forma:SolidPeso molecolare:279.33Ro 43-5054
CAS:Ro 43-5054 is a small molecular, noncyclic peptidomimetic inhibitor.Formula:C24H27N5O7Purezza:98%Colore e forma:SolidPeso molecolare:497.5
