Ferroptosi
La ferroptosi è una forma di morte cellulare regolata caratterizzata dall'accumulo di perossidi lipidici e dallo stress ossidativo dipendente dal ferro. A differenza dell'apoptosi, la ferroptosi non è guidata dalle caspasi, ma piuttosto dal fallimento delle difese antiossidanti cellulari, che porta alla morte cellulare. Gli inibitori e gli induttori della ferroptosi sono fondamentali per studiare questa particolare via di morte cellulare, implicata in varie malattie, tra cui il cancro, la neurodegenerazione e il danno da ischemia-riperfusione. Presso CymitQuimica, offriamo una vasta gamma di modulatori della ferroptosi di alta qualità per supportare la tua ricerca sui meccanismi di morte cellulare, stress ossidativo e patologia delle malattie.
Trovati 225 prodotti di "Ferroptosi"
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Nordihydroguaiaretic acid
CAS:<p>Nordihydroguaiaretic acid (NDGA) is a natural lipoxygenase (5-LOX) inhibitor. Nordihydroguaiaretic acid has antioxidant effect. Cost-effective and quality-assured.</p>Formula:C18H22O4Purezza:97.82% - 99.91%Colore e forma:SolidPeso molecolare:302.36NADPH tetrasodium salt
CAS:NADPH tetrasodium salt is the reduced form of the electron acceptor nicotinamide adenine dinucleotide phosphate, which acts as an electron donor in a variety ofFormula:C21H26N7Na4O17P3Purezza:97.15% - >99.99%Colore e forma:SolidPeso molecolare:833.35FINO2
CAS:FINO2, a strong ferroptosis trigger, blocks GPX4, oxidizes Fe2+, stable in different pH, causes lipid peroxidation.Formula:C15H28O3Purezza:97.27%Colore e forma:SoildPeso molecolare:256.38Frataxin-IN-1
CAS:Frataxin-IN-1 inhibits the mitochondrial protein Frataxin with IC50 45 μM and is used in Friedreich’s ataxia research linked to mitochondrial defects.Formula:C20H23NO6Purezza:99.34%Peso molecolare:373.4Microtubule inhibitor 8
CAS:<p>Microtubule Inhibitor 8 (MP-HJ-1b) serves as a potent disruptor of microtubule function, inducing cell death via ferroptosis and demonstrating anti-tumor effects [1] [2].</p>Formula:C21H15N3O2SColore e forma:SolidPeso molecolare:373.43Anti-Mouse IL-1b Antibody (B122)
Anti-Mouse IL-1b Antibody (B122) is a mab inhibitor, blocks IL-1β signaling, reducing monocyte infiltration and alleviating T cell exhaustion.Colore e forma:Odour LiquidPioglitazone-d4
CAS:Pioglitazone D4 is a deuterium labeled Pioglitazone. Pioglitazone is a agonist of PPARγ .Formula:C19H20N2O3SPurezza:98%Colore e forma:SolidPeso molecolare:360.46CN128 hydrochloride
CAS:<p>CN128 hydrochloride is an oral, selective hydroxypyridone iron chelator for β-thalassemia research.</p>Formula:C15H18ClNO3Colore e forma:SolidPeso molecolare:295.76IM-93
CAS:IM-93 inhibits ferroptosis and NETosis with an IC< sub>50 of 0.45 μM for cell death inhibition [1].Formula:C21H28N4O2Colore e forma:SolidPeso molecolare:368.47Tubulin inhibitor 30
CAS:Tubulin Inhibitor 30, exhibiting an IC50 value of 0.52 μM, functions as an inhibitor of tubulin assembly. Additionally, it can induce ferroptosis.Formula:C22H19N3O5Colore e forma:SolidPeso molecolare:405.4NPD4928
CAS:NPD4928 boosts cancer cell sensitivity to GPX4 inhibitors, hinting at therapeutic potential through ferroptosis.Formula:C29H32N2O6Colore e forma:SolidPeso molecolare:504.57CGP 65015
CAS:CGP 65015 is an oral iron chelator and can mobilize iron deposits.Formula:C14H15NO4Purezza:98%Colore e forma:SolidPeso molecolare:261.27Ferroptosis inducer-1
CAS:Ferroptosis inducer-1 is a Ferroptosis inducer with antitumor potential .Formula:C25H21ClN2O5Colore e forma:SolidPeso molecolare:464.9W1131
CAS:W1131 is a potent STAT3 inhibitor and ferroptosis trigger, reducing cancer progression and 5-FU resistance.Formula:C23H19N5O4Colore e forma:SolidPeso molecolare:429.43Ferroptosis-IN-4
CAS:Ferroptosis-IN-4 (compound 6k), an inhibitor of ferroptosis, exhibits an EC50 of 20 μM and lacks significant cytotoxicity. It demonstrates a protective role in glycerol-induced RM-AKI mice by alleviating kidney dysfunction [1].Formula:C17H24ClN3O2Peso molecolare:337.84YL-939
YL-939 is a potent inhibitor of ferroptosis, targeting the PHB2/ferritin/iron axis to impede this form of cell death.Formula:C25H26N6OColore e forma:SolidPeso molecolare:426.51Anticancer agent 147
CAS:Compound 6j (Anticancer agent 147), a sophoridine derivative and ferroptosis inducer, promotes intracellular accumulation of Fe2+, reactive oxygen species (ROSFormula:C32H40BrN3O2Purezza:98%Colore e forma:SolidPeso molecolare:578.58Erastin2
CAS:<p>Erastin2 is an iron death inducer that induces cell death by binding to the lipophilic free radical trapping antioxidant ferrostatin-1 or the iron chelator DFO.</p>Formula:C36H35ClN4O4Purezza:99.63%Colore e forma:SolidPeso molecolare:623.14FA16
FA16 is a selective, metabolically stable ferroptosis inducer with an IC50 value of 1.26 μM.FA16 is a derivative of 2-(trifluoromethyl)benzimidazole.FA16Formula:C22H27F3N4O2SPurezza:99.44%Colore e forma:SolidPeso molecolare:468.54BCP-T.A
CAS:BCP-T.A is an iron death inducer that acts by binding to GPX4.Formula:C23H19Cl2N3OSPurezza:99.49%Colore e forma:SolidPeso molecolare:456.39
