Ferroptosi
La ferroptosi è una forma di morte cellulare regolata caratterizzata dall'accumulo di perossidi lipidici e dallo stress ossidativo dipendente dal ferro. A differenza dell'apoptosi, la ferroptosi non è guidata dalle caspasi, ma piuttosto dal fallimento delle difese antiossidanti cellulari, che porta alla morte cellulare. Gli inibitori e gli induttori della ferroptosi sono fondamentali per studiare questa particolare via di morte cellulare, implicata in varie malattie, tra cui il cancro, la neurodegenerazione e il danno da ischemia-riperfusione. Presso CymitQuimica, offriamo una vasta gamma di modulatori della ferroptosi di alta qualità per supportare la tua ricerca sui meccanismi di morte cellulare, stress ossidativo e patologia delle malattie.
Trovati 225 prodotti di "Ferroptosi"
Ordinare per
Purezza (%)
0
100
|
0
|
50
|
90
|
95
|
100
SP-420
CAS:SP-420 is a novel orally active iron chelator.Formula:C16H21NO6SPurezza:99.39%Colore e forma:SolidPeso molecolare:355.41ML-210
CAS:ML-210 (CID 49766530) is a glutathione peroxidase 4 (GPX4) inhibitor. ML-210 has antitumor activity and induces ferroptosis. Cost-effective and quality-assured.Formula:C22H20Cl2N4O4Purezza:97% - 99.03%Colore e forma:SolidPeso molecolare:475.32Troglitazone
CAS:Troglitazone (Romglizone) is a PPARγ agonist with anti-inflammatory and anti-tumor activity.Formula:C24H27NO5SPurezza:98% - 99.8%Colore e forma:Yellow SolidPeso molecolare:441.54L-BUTHIONINE-(S,R)-SULFOXIMINE
CAS:L-Buthionine-(S,R)-sulfoximine is a cell-permeable and irreversible inhibitor of γ-glutamylcysteine synthetase that induces oxidative stress by depleting GSH.Formula:C8H18N2O3SPurezza:97.07% - ≥98%Colore e forma:White Fine PowderPeso molecolare:222.31DL-Buthionine-(S,R)-sulfoximine
CAS:DL-Buthionine-(S,R)-sulfoximine (Butionine sulfoximine) is an inhibitor of γ-glutamylcysteine synthetase for the treatment of solid tumors.Formula:C8H18N2O3SPurezza:98% - 99.64%Colore e forma:White Fine PowderPeso molecolare:222.31SRS16-86
CAS:SRS16-86 is a novel third-generation ferrostatin, is an inhibitor of ferroptosis.Formula:C26H32N4O2Purezza:97.73%Colore e forma:SolidPeso molecolare:432.56Pseudolaric Acid B
CAS:Pseudolaric acid B, a natural diterpenoid compound, is isolated from Pseudolarix kaempferi.Formula:C23H28O8Purezza:98.91% - 99.84%Colore e forma:SolidPeso molecolare:432.46Bay 11-7085
CAS:Bay 11-7085 can irreversibly inhibit the IκBα phosphorylation induced by TNFα (IC50: 10 μM).Formula:C13H15NO2SPurezza:99.76% - 99.94%Colore e forma:White SolidPeso molecolare:249.33Levobupivacaine
CAS:<p>Levobupivacaine is an amino-amide local anaesthetic drug belonging to the family of n-alkylsubstituted pipecoloxylidide.</p>Formula:C18H28N2OPurezza:99.72%Colore e forma:SolidPeso molecolare:288.43Liproxstatin-1
CAS:Liproxstatin-1 is a potent and selective inhibitor of iron death (IC50=22 nM).Formula:C19H21ClN4Purezza:97.11% - 99.44%Colore e forma:SolidPeso molecolare:340.85Rosiglitazone hydrochloride
CAS:Rosiglitazone hydrochloride (BRL-49653 HCl) is a blood glucose-lowering drugs, stimulating insulin secretion by binding to the PPAR receptors in fat cells.Formula:C18H19N3O3S·HClPurezza:99.63% - 99.79%Colore e forma:SolidPeso molecolare:393.89SP600125
CAS:SP600125 (JNK Inhibitor II) is a JNK inhibitor that inhibits JNK1, JNK2, and JNK3 (IC50=40/40/90 nM) with oral potency, reversibility, and ATP-competitiveFormula:C14H8N2OPurezza:97.63% - 99.82%Colore e forma:SolidPeso molecolare:220.23NADPH tetracyclohexanamine
CAS:<p>NADPH tetracyclohexanamine (NADPH (tetracyclohexanamine)) is a cofactor and biological reducing agent.</p>Formula:C45H82N11O17P3Purezza:98.73% - 99.05%Colore e forma:SolidPeso molecolare:1142.12L-Cystine
CAS:<p>L-Cystine (Cystine Acid) is not considered one of the 20 amino acids, L-Cystine (Cystine Acid) is a sulfur-containing derivative obtained from oxidation of</p>Formula:C6H12N2O4S2Purezza:99.59% - 99.85%Colore e forma:White Solid PowderPeso molecolare:240.30Rosiglitazone
CAS:Rosiglitazone (BRL49653) is a PPARγ agonist, TRPC5 activator, and TRPM3 inhibitor with oral activity.Formula:C18H19N3O3SPurezza:98.61% - 99.87%Colore e forma:White To Off-White Crystalline PowderPeso molecolare:357.43JKE-1674
CAS:JKE-1674 is an orally active glutathione peroxidase 4 (GPX4) inhibitor and the active metabolite of ML-210.Cost-effective and quality-assured.Formula:C20H20Cl2N4O4Purezza:98.02% - 98.4%Colore e forma:SolidPeso molecolare:451.3L-Glutamic acid
CAS:<p>L-Glutamic acid is an agonist of glutamate receptors, including metabotropic glutamate receptors (mGluR), AMPA, NMDA, and KA. High-Quality, Low-Cost!</p>Formula:C5H9NO4Purezza:99.14% - 99.55%Colore e forma:White Solid CrystallinePeso molecolare:147.13ML385
CAS:ML385 is an NRF2 inhibitor (IC50=1.9 μM) with novelty and specificity.Formula:C29H25N3O4SPurezza:98.08% - >99.99%Colore e forma:SolidPeso molecolare:511.59Necrostatin-1
CAS:Necrostatin-1 (Nec-1) is a necrotic apoptosis inhibitor and RIP1 inhibitor with specificity.Formula:C13H13N3OSPurezza:99.25% - >99.99%Colore e forma:SolidPeso molecolare:259.33Siramesine hydrochloride
CAS:Siramesine hydrochloride (Lu 28-179 hydrochloride) is a selective sigma-2 receptor agonist, which has been shown to trigger cell death of Y cells and to exhibitFormula:C30H32ClFN2OPurezza:99.72% - >99.99%Colore e forma:SolidPeso molecolare:491.04
