c-Myc
Gli inibitori di c-Myc prendono di mira la proteina c-Myc, un fattore di trascrizione che svolge un ruolo cruciale nella crescita cellulare, proliferazione e apoptosi. c-Myc regola l'espressione di numerosi geni coinvolti nel ciclo cellulare ed è spesso sovraespresso in vari tipi di cancro, portando a una proliferazione cellulare incontrollata e alla crescita tumorale. L'inibizione di c-Myc può interrompere questi processi, inducendo l'arresto del ciclo cellulare e l'apoptosi nelle cellule tumorali. Gli inibitori di c-Myc sono strumenti importanti nella ricerca sul cancro e nello sviluppo terapeutico. Presso CymitQuimica, offriamo una vasta gamma di inibitori di c-Myc di alta qualità per supportare la tua ricerca in oncologia, regolazione del ciclo cellulare e controllo trascrizionale.
Trovati 69 prodotti di "c-Myc"
Ordinare per
Purezza (%)
0
100
|
0
|
50
|
90
|
95
|
100
c-Myc inhibitor 8
CAS:<p>c-Myc inhibitor 8 suppresses cell growth in various cancers and is used in research.</p>Formula:C19H12BrClF3NO3S2Colore e forma:SolidPeso molecolare:538.79m-Se3
CAS:<p>m-Se3 is a potent, selective inhibitor of c-MYC transcription with demonstrated capability to inhibit tumor growth and exhibit anti-cancer activity [1].</p>Formula:C29H23IN2SePurezza:98%Colore e forma:SolidPeso molecolare:605.37SYHA1815
CAS:<p>SYHA1815, an orally active RET inhibitor (IC50=0.9 nmol/L), demonstrates antitumor activity. It exhibits greater selectivity for RET over KDR (IC50=15.9 nmol/L). SYHA1815 operates by downregulating c-Myc, arresting the G1 cell cycle, and inhibiting RET-driven cell proliferation.</p>Formula:C27H26ClF4N5OColore e forma:SolidPeso molecolare:547.98KI-CDK9d-32
CAS:<p>KI-CDK9d-32 is a CDK9 PROTAC degrader with a DC50 of 0.89 nM. It facilitates the ubiquitination and degradation of CDK9, inhibits the MYC pathway, and disrupts nucleolar homeostasis. KI-CDK9d-32 demonstrates anticancer activity.</p>Formula:C39H45N9O4Colore e forma:SolidPeso molecolare:703.83c-Myc inhibitor 4
<p>Potent oral c-Myc inhibitor 4 reduces the proto-oncogene linked to tumor development.</p>Formula:C26H33FN6O3Colore e forma:SolidPeso molecolare:496.58BRD4 Inhibitor-40
CAS:<p>BRD4 Inhibitor-40 (Compound 23) functions as an inhibitor of BRD, effectively targeting BRD4-BD1, BRD4-BD2, BRD2-BD1, and BRD2-BD2, with IC50 values of 16.1, 142.18, 29.35, and 302.35 nM, respectively. It modulates the expression of c-Myc and p21, induces cell cycle arrest in the G1 phase, and inhibits Pkd1-deficient (PN) renal cystic epithelial cells. Additionally, it prevents renal cyst formation in both Madin-Darby canine kidney and embryonic kidney cyst models, and demonstrates renal cyst inhibition activity in mouse models.</p>Formula:C27H32N8OColore e forma:SolidPeso molecolare:484.596MY05
CAS:<p>MY05 selectively targets c-MYC within cells and disrupts the interaction between MYC and MAX. It binds to intracellular c-MYC, modulating its thermal stability, reducing the transcriptional targets of c-MYC, and exhibiting anticancer activity (TNBC, triple-negative breast cancer).</p>Formula:C19H11ClN4OColore e forma:SolidPeso molecolare:346.77JY-3-094
CAS:<p>JY-3-094 is a selective Myc inhibitor that targets the hydrophobic domain of Myc and inhibits the formation of the Myc-Max heterodimer, with an IC50 of 33 μM, and can be used for cancer research.</p>Formula:C13H8N4O5Purezza:98.72%Colore e forma:SolidPeso molecolare:300.23β-catenin-IN-8
CAS:<p>β-catenin-IN-8 (Compound 25) is an inhibitor of β-catenin. It effectively lowers the levels of both β-catenin and c-Myc proteins and suppresses Wnt target genes (Fgf20 and Sall4). Additionally, β-catenin-IN-8 exhibits anticancer activity against colorectal cancer and possesses metabolic stability.</p>Formula:C15H12ClN3O2SColore e forma:SolidPeso molecolare:333.79
