PKC
Gli inibitori della proteina chinasi C (PKC) prendono di mira la famiglia delle chinasi PKC, coinvolte in una vasta gamma di processi cellulari, tra cui la regolazione del ciclo cellulare, l'apoptosi e la differenziazione. La PKC svolge un ruolo chiave nelle vie di trasduzione del segnale che influenzano la proliferazione e la sopravvivenza cellulare. L'inibizione della PKC può portare a cambiamenti nella progressione del ciclo cellulare, rendendo questi inibitori strumenti preziosi nella ricerca sul cancro, la neurobiologia e le malattie cardiovascolari. Presso CymitQuimica, offriamo una selezione diversificata di inibitori della PKC di alta qualità per supportare la tua ricerca sulla trasduzione del segnale, la regolazione del ciclo cellulare e lo sviluppo terapeutico.
Trovati 111 prodotti di "PKC"
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Sotrastaurin
CAS:Sotrastaurin (AEB071) is a potent pan-PKC inhibitor (Kis: 0.95/0.64/2.1/3.2/1.8/0.22 nM for PKCα/βI/δ/ε/η/θ).Formula:C25H22N6O2Purezza:98% - 99.70%Colore e forma:SolidPeso molecolare:438.48Ref: TM-T6278
1mg47,00€5mg90,00€10mg142,00€25mg268,00€50mg445,00€100mg638,00€200mg892,00€1mL*10mM (DMSO)99,00€D-ERYTHRO-SPHINGOSINE
CAS:<p>D-erythro-Sphingosine (trans-4-Sphingenine) is a protein kinase C (PKC) inhibitor. D-erythro-Sphingosine (Erythrosphingosine) is also a PP2A activator</p>Formula:C18H37NO2Purezza:98% - 99.85%Colore e forma:SolidPeso molecolare:299.49Decursin
CAS:Decursin: potential antiepileptic, hepatoprotective, anti-cancer, anti-amnesic; affects NOX activation, PKCα/MAPK/NF-κB pathways, AChE.Formula:C19H20O5Purezza:97.22% - 99.91%Colore e forma:SolidPeso molecolare:328.36Ref: TM-T3S1416
1mg43,00€5mg88,00€10mg119,00€25mg259,00€50mg462,00€100mg662,00€500mg1.359,00€1mL*10mM (DMSO)87,00€Protein Kinase C 19-31 acetate
PKC 19-31 acetate, a serine-altered PKCa-derived PKC inhibitor, tests PKC activity.Formula:C69H122N26O18Purezza:>99.99%Colore e forma:SolidPeso molecolare:1603.9Hypericin
CAS:Hypericin (Cyclosan) is a natural anthraquinone compound. Hypericin exhibits antimicrobial, antiviral, antitumor, and antidepressant effects. Cost-effective and quality-assured.Formula:C30H16O8Purezza:98.90% - ≥98%Colore e forma:Red-Coloured Anthraquinone-DerivativePeso molecolare:504.44Ref: TM-T6S0923
1mg57,00€5mg127,00€10mg182,00€25mg360,00€50mg532,00€100mg743,00€500mg1.510,00€1mL*10mM (DMSO)140,00€1,2-Dimyristoyl-sn-glycerol
CAS:1,2-Dimyristoyl-sn-glycerol (1,2-DMG) is able to increase AChE activity by 35-40% at concentrations of 25 micrograms/ml in the parasite S. mansoni..Formula:C31H60O5Purezza:99.96%Colore e forma:White Powder With LumpsPeso molecolare:512.81Hispidin
CAS:Hispidin is a polyphenol originally, including antioxidant, anti-inflammatory, and cytoprotective propertiesFormula:C13H10O5Purezza:98.27%Colore e forma:White Crystalline PowderPeso molecolare:246.22Ref: TM-T7792
1mg88,00€5mg187,00€10mg298,00€25mg533,00€50mg747,00€100mg1.017,00€1mL*10mM (DMSO)207,00€Taurochenodeoxycholic acid sodium
CAS:Sodium taurochenodeoxycholate: induces apoptosis, anti-inflammatory, boosts insulin, stimulates α2-cells, increases [Ca(2+)](c).Formula:C26H44NNaO6SPurezza:98.23% - 99.56%Colore e forma:White To Off-White PowderPeso molecolare:521.68Bisindolylmaleimide I
CAS:Bisindolylmaleimide I (GF109203X) is a potent and highly selective protein kinase C (PKC) inhibitor with a Ki of 14 nM.Formula:C25H24N4O2Purezza:97.51% - 98.75%Colore e forma:Orange SolidPeso molecolare:412.48Ref: TM-T6513
5mg66,00€10mg99,00€25mg188,00€50mg350,00€100mg469,00€1mL*10mM (DMSO)Prezzo su richiestaFasudil hydrochloride
CAS:Fasudil hydrochloride (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK with Ki of 0.33 μM, 1.0 μM, 9.3 μM and 55 μM, respectively.Formula:C14H18ClN3O2SPurezza:99.54% - ≥95%Colore e forma:White SolidPeso molecolare:327.83Mitoxantrone
CAS:<p>Mitoxantrone: anthracenedione antibiotic, disrupts DNA/RNA replication, binds to topoisomerase II, less cardiotoxic than doxorubicin.</p>Formula:C22H28N4O6Purezza:96.29% - 98.74%Colore e forma:Blue PowderPeso molecolare:444.48HA-100
CAS:<p>HA-100 is an inhibitor of protein kinase</p>Formula:C13H15N3O2SPurezza:99.44%Colore e forma:Pale Yellow Crystalline SolidPeso molecolare:277.34Ruboxistaurin hydrochloride
CAS:Ruboxistaurin HCl (LY 333531) selectively inhibits PKCβI/II with IC50 of 4.7/5.9 nM; much less effective on other PKC types and ATP-kinases.Formula:C28H28N4O3·HClPurezza:99.14% - 99.28%Colore e forma:SolidPeso molecolare:505.01Ref: TM-T3689
1mg71,00€2mg93,00€5mg157,00€10mg256,00€25mg513,00€50mg740,00€100mg1.035,00€500mg2.072,00€1mL*10mM (DMSO)202,00€Ionomycin calcium
CAS:<p>Ionomycin calcium (SQ23377 calcium) is an effective and selective calcium ionophore, exhibiting high specificity for calcium ions. Cost-effective and quality-assured.</p>Formula:C41H70CaO9Purezza:98% - 98.11%Colore e forma:SolidPeso molecolare:747.07Phorbol 12,13-dibutyrate
CAS:Phorbol 12,13-dibutyrate (Phorbol dibutyrate) is a PKC activator that induces contraction of isolated rabbit vascular smooth muscle.Formula:C28H40O8Purezza:99.32% - 99.37%Colore e forma:SolidPeso molecolare:504.61Ref: TM-T16526
1mg62,00€5mg169,00€10mg283,00€25mg560,00€50mg873,00€100mg1.388,00€200mg1.872,00€1mL*10mM (DMSO)180,00€PS315
CAS:PS315, a PS48 derivative, allosterically inhibits PKCζ/η (IC50: 10/30 μM), targeting aPKC's PIF-pocket, with anti-cancer properties.Formula:C23H19ClO2Purezza:98%Colore e forma:SolidPeso molecolare:362.85AJH-836
CAS:AJH-836 is a compound that activates Munc13-1 and PKC ε/α, demonstrating a dissociation constant (Kd) of 4.5 nM for PKCα, and facilitates the translocation ofFormula:C22H38O5Purezza:98%Colore e forma:SolidPeso molecolare:382.53CGP60474
CAS:CGP60474 is an inhibitor of VEGFR-2 (IC50 = 84 nM) and an inhibitor of ATP-competitive PKC.Formula:C18H18ClN5OPurezza:98.81%Colore e forma:SolidPeso molecolare:355.82Ref: TM-T14943
1mg35,00€2mg48,00€5mg74,00€10mg97,00€25mg187,00€50mg331,00€100mg547,00€1mL*10mM (DMSO)82,00€SC-10
CAS:SC-10 is a direct activator of PKC with potential antiproliferative activity, useful in leukemia research.Formula:C17H22ClNO2SPurezza:99.24% - 99.58%Colore e forma:SolidPeso molecolare:339.88NSC668394
CAS:<p>NSC668394 is an ezrin phosphorylation inhibitor.NSC668394 has antitumor activity and increases ezrin cleavage.NSC668394 can be used to study tumor metastasis.</p>Formula:C17H12Br2N2O3Purezza:99.29% - 99.29%Colore e forma:SolidPeso molecolare:452.1
