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Dynamin

Dynamin

Gli inibitori della dinamina prendono di mira la dinamina, un enzima GTPasi che svolge un ruolo cruciale nell'endocitosi, nel traffico vescicolare e nella citocinesi. La dinamina è coinvolta nella scissione delle vescicole dalle membrane ed è essenziale per la corretta distribuzione dei componenti cellulari durante la divisione cellulare. Inibire la dinamina può interrompere questi processi, portando a difetti nella divisione cellulare e inducendo l'arresto del ciclo cellulare. Gli inibitori della dinamina sono strumenti preziosi per lo studio dell'endocitosi, della divisione cellulare e della dinamica delle membrane. Presso CymitQuimica, offriamo una gamma di inibitori della dinamina di alta qualità per supportare la tua ricerca in biologia cellulare, traffico di membrane e regolazione del ciclo cellulare.

Trovati 26 prodotti di "Dynamin"

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  • Anti-Clathrin Heavy Chain Antibody


    Anti-Clathrin Heavy Chain Antibody is a human-source antibody expressed in CHO cells, specifically targeting the Clathrin Heavy Chain. For isotype control, please refer to Human IgG1 kappa, Isotype Control.
    Colore e forma:Odour Liquid
  • TAT-P110

    CAS:
    TAT-P110 is a peptide inhibitor that disrupts the interaction between Drp1 and Fis1, effectively reducing pathological changes in various models of neurodegenerative diseases, ischemia, and sepsis without impairing the physiological function of Drp1.
    Formula:C100H178N44O26
    Peso molecolare:2412.76
  • Dynamin inhibitory peptide TFA


    Dynamin inhibitory peptide TFA hinders dynamin-amphiphysin interaction and endocytosis, affecting dopamine D3 and GABA A receptors.
    Formula:C49H81F3N18O16
    Colore e forma:Solid
    Peso molecolare:1235.27
  • Drp1 peptide inhibitor P110

    CAS:
    <p>Compound P110 (Drp1 peptide inhibitor P110) is a selective Drp1 peptide inhibitor with neuroprotective effects. It inhibits the activation of Drp1, prevents Drp1 mitochondrial translocation induced by MPTP, and alleviates dopamine neuron loss, dopaminergic terminal damage, and behavioral deficits caused by MPTP. This compound is useful for Alzheimer's disease research. Additionally, Compound P110 reduces mitochondrial and organ damage in animal models of Huntington's disease, cerebral ischemia, and myocardial infarction.</p>
    Formula:C100H179N45O25
    Colore e forma:Solid
    Peso molecolare:2411.78
  • IIQLPEIVVV TFA


    IIQLPEIVVV TFA serves as a specific inhibitor targeting the Drp1-Mff interaction. This compound discriminates between physiological and pathological fission, hindering physiological fission which leads to mitochondrial dysfunction. IIQLPEIVVV TFA is also utilized in research related to Huntington's disease.
    Formula:C54H95N11O14·xC2HF3O2
    Colore e forma:Solid
    Peso molecolare:1122.40 (free base)
  • ES9-17

    CAS:
    ES9-17, an ES9 analog, blocks clathrin-mediated endocytosis and impairs Arabidopsis root growth, affecting FM4-64 and transferrin uptake.
    Formula:C10H8BrNO2S2
    Purezza:99.93%
    Colore e forma:Solid
    Peso molecolare:318.21
  • Dynamin IN-2

    CAS:
    <p>Dynamin IN-2 (compound 43) is a Wiskostatin analogue.</p>
    Formula:C22H21ClN2O
    Purezza:99.36% - 99.37%
    Colore e forma:Soild
    Peso molecolare:364.87
  • DynaMin inhibitory peptide, myristoylated

    CAS:
    Cell-permeable dynamin inhibitor; blocks its binding to amphiphysin, hindering endocytosis; curbs NMDA receptor internalization.
    Formula:C61H107N19O14
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:1330.64
  • Schaftoside

    CAS:
    Schaftoside (APIGENIN-6-GLUCOSIDE-8-ARABINOSIDE) has antioxidant and anticancer activity.
    Formula:C26H28O14
    Purezza:98% - >99.99%
    Colore e forma:Solid
    Peso molecolare:564.49
  • Mdivi-1

    CAS:
    Mdivi-1 (Mitochondrial division inhibitor 1) is a mitochondrial division inhibitor that inhibits DRP1 and Dynamin I (IC50=1-10 μM).
    Formula:C15H10Cl2N2O2S
    Purezza:96.57% - 99.23%
    Colore e forma:Solid
    Peso molecolare:353.22
  • Dynasore

    CAS:
    <p>Dynasore, a cell-permeable dynamin inhibitor, blocks GTPase of dynamin 1/2 and Drp1 (IC50: 15 μM) without affecting other small GTPases.</p>
    Formula:C18H14N2O4
    Purezza:95.85% - 99.22%
    Colore e forma:Solid
    Peso molecolare:322.31
  • Tetradecyltrimethylammonium bromide

    CAS:
    Tetradecyltrimethylammonium bromide (MitMAB) is a Dynamin GTPase activity inhibitor and a cationic surfactant with asymmetrical structure.
    Formula:C17H38BrN
    Purezza:99.80%
    Colore e forma:Solid
    Peso molecolare:336.39
  • Trimethyloctadecylammonium bromide

    CAS:
    <p>Trimethyloctadecylammonium bromide is an inhibitor of Dynamin I(IC50 : 1.9 μM) and also inhibits Dynamin Ⅱ.</p>
    Formula:C21H46N·Br
    Purezza:99.09%
    Colore e forma:Solid Solid
    Peso molecolare:392.5
  • Dynamin inhibitory peptide, myristoylated acetate


    Myristoylated acetate peptide inhibits DynaMin, blocking amphiphysin binding; myristoylated TFA variant hinders endocytosis.
    Formula:C63H111N19O16
    Purezza:99.42%
    Colore e forma:Solid
    Peso molecolare:1390.67
  • Hydroxy-Dynasore

    CAS:
    Hydroxy-Dynasore (Dyngo-4a) , a effective dynamin inhibitor, inhibits withDynI (brain), DynI (rec), and DynII (rec) of IC50 of 0.38 μM, 1.1 μM, and 2.3 μM,
    Formula:C18H14N2O5
    Purezza:97.60% - >99.99%
    Colore e forma:Solid
    Peso molecolare:338.31
  • DNM1 Protein, Human, Recombinant (His)


    Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP.
    Colore e forma:Lyophilized Powder
    Peso molecolare:32.2 kDa (predicted)
  • Dynamin IN-1

    CAS:
    Dynamin IN-1 is a potent dynamin inhibitor with an IC 50 value of 1.0 µM .
    Formula:C23H24N2O
    Colore e forma:Solid
    Peso molecolare:344.45
  • MB 0223

    CAS:
    DRP1 partial inhibitor (IC50 = 1.2 μM), selective over OPA1/DYN1, boosts mtDNA in mfn1-knockout MEFs.
    Formula:C26H27N5OS
    Colore e forma:Solid
    Peso molecolare:457.59
  • Clathrin-IN-25

    CAS:
    Clathrin-IN-25 is the most effective clathrin terminal domain-amphiphysin inhibitor reported to date.
    Formula:C19H13KNO5S
    Colore e forma:Solid
    Peso molecolare:406.47
  • DRP1i27

    CAS:
    DRP1i27 inhibits human Drp1 at GTPase site, prevents mitochondrial fission, and shields cells from ischemia-reperfusion damage.
    Formula:C20H26N6O
    Colore e forma:Solid
    Peso molecolare:366.46