Dynamin
Gli inibitori della dinamina prendono di mira la dinamina, un enzima GTPasi che svolge un ruolo cruciale nell'endocitosi, nel traffico vescicolare e nella citocinesi. La dinamina è coinvolta nella scissione delle vescicole dalle membrane ed è essenziale per la corretta distribuzione dei componenti cellulari durante la divisione cellulare. Inibire la dinamina può interrompere questi processi, portando a difetti nella divisione cellulare e inducendo l'arresto del ciclo cellulare. Gli inibitori della dinamina sono strumenti preziosi per lo studio dell'endocitosi, della divisione cellulare e della dinamica delle membrane. Presso CymitQuimica, offriamo una gamma di inibitori della dinamina di alta qualità per supportare la tua ricerca in biologia cellulare, traffico di membrane e regolazione del ciclo cellulare.
Trovati 28 prodotti per "Dynamin".
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DynaMin inhibitory peptide, myristoylated
CAS:Cell-permeable dynamin inhibitor; blocks its binding to amphiphysin, hindering endocytosis; curbs NMDA receptor internalization.Formula:C61H107N19O14Purezza:98%Colore e forma:SolidPeso molecolare:1330.64TAT-P110
CAS:TAT-P110 is a peptide inhibitor that disrupts the interaction between Drp1 and Fis1, effectively reducing pathological changes in various models of neurodegenerative diseases, ischemia, and sepsis without impairing the physiological function of Drp1.Formula:C100H178N44O26Colore e forma:SolidPeso molecolare:2412.76Dynamin inhibitory peptide TFA
Dynamin inhibitory peptide TFA hinders dynamin-amphiphysin interaction and endocytosis, affecting dopamine D3 and GABA A receptors.Formula:C49H81F3N18O16Colore e forma:SolidPeso molecolare:1235.27Drp1 peptide inhibitor P110 TFA
Drp1 peptide inhibitor P110 (Compound P110) TFA is a selective Drp1 peptide inhibitor with neuroprotective properties. It suppresses the activation of Drp1, prevents Drp1 mitochondrial translocation induced by MPTP, and reduces MPTP-induced loss of dopaminergic neurons, damage to dopaminergic nerve terminals, and behavioral defects, making it useful for Alzheimer's disease research. Furthermore, Drp1 peptide inhibitor P110 TFA mitigates mitochondrial and organ damage in animal models of Huntington's disease, cerebral ischemic injury, and myocardial infarction.IIQLPEIVVV TFA
IIQLPEIVVV TFA serves as a specific inhibitor targeting the Drp1-Mff interaction. This compound discriminates between physiological and pathological fission, hindering physiological fission which leads to mitochondrial dysfunction. IIQLPEIVVV TFA is also utilized in research related to Huntington's disease.Formula:C54H95N11O14·xC2HF3O2Colore e forma:SolidPeso molecolare:1122.40 (free base)ES9-17
CAS:ES9-17, an ES9 analog, blocks clathrin-mediated endocytosis and impairs Arabidopsis root growth, affecting FM4-64 and transferrin uptake.Formula:C10H8BrNO2S2Purezza:99.95%Colore e forma:SolidPeso molecolare:318.21Dynamin IN-2
CAS:Dynamin IN-2 (compound 43) is a Wiskostatin analogue.Formula:C22H21ClN2OPurezza:99.40% - 99.52%Colore e forma:SolidPeso molecolare:364.868Schaftoside
CAS:Schaftoside (APIGENIN-6-GLUCOSIDE-8-ARABINOSIDE) has antioxidant and anticancer activity.Formula:C26H28O14Purezza:98% - >99.99%Colore e forma:SolidPeso molecolare:564.4921Mdivi-1
CAS:Mdivi-1 (Mitochondrial division inhibitor 1) is a mitochondrial division inhibitor that inhibits DRP1 and Dynamin I (IC50=1-10 μM).Formula:C15H10Cl2N2O2SPurezza:96.57% - 99.23%Colore e forma:SolidPeso molecolare:353.223Dynasore
CAS:Dynasore, a cell-permeable dynamin inhibitor, blocks GTPase of dynamin 1/2 and Drp1 (IC50: 15 μM) without affecting other small GTPases.Formula:C18H14N2O4Purezza:95.85% - 98.59%Colore e forma:SolidPeso molecolare:322.3148Tetradecyltrimethylammonium bromide
CAS:Tetradecyltrimethylammonium bromide (MitMAB) is a Dynamin GTPase activity inhibitor and a cationic surfactant with asymmetrical structure.Formula:C17H38BrNPurezza:99.80%Colore e forma:SolidPeso molecolare:336.39Trimethyloctadecylammonium bromide
CAS:Trimethyloctadecylammonium bromide is an inhibitor of Dynamin I(IC50 : 1.9 μM) and also inhibits Dynamin Ⅱ.Formula:C21H46N·BrPurezza:99.09%Colore e forma:SolidPeso molecolare:392.5Dynamin inhibitory peptide, myristoylated acetate
Myristoylated acetate peptide inhibits DynaMin, blocking amphiphysin binding; myristoylated TFA variant hinders endocytosis.Formula:C63H111N19O16Purezza:99.42%Colore e forma:SolidPeso molecolare:1390.67Hydroxy-Dynasore
CAS:Hydroxy-Dynasore (Dyngo-4a) , a effective dynamin inhibitor, inhibits withDynI (brain), DynI (rec), and DynII (rec) of IC50 of 0.38 μM, 1.1 μM, and 2.3 μM,Formula:C18H14N2O5Purezza:97.60% - >99.99%Colore e forma:SolidPeso molecolare:338.31DNM1 Protein, Human, Recombinant (His)
Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP.Colore e forma:Lyophilized PowderPeso molecolare:32.2 kDa (predicted)Ellipticine quinone
CAS:Ellipticine quinone (NSC-383230) outperforms mdivi-1 in inhibiting Drp1, reduces lung cancer growth, and lessens IR injury by curbing mitochondrial issues.Formula:C15H8N2O2Colore e forma:SolidPeso molecolare:248.24Drp1 peptide inhibitor P110
CAS:Compound P110 (Drp1 peptide inhibitor P110) is a selective Drp1 peptide inhibitor with neuroprotective effects. It inhibits the activation of Drp1, prevents Drp1 mitochondrial translocation induced by MPTP, and alleviates dopamine neuron loss, dopaminergic terminal damage, and behavioral deficits caused by MPTP. This compound is useful for Alzheimer's disease research. Additionally, Compound P110 reduces mitochondrial and organ damage in animal models of Huntington's disease, cerebral ischemia, and myocardial infarction.Formula:C100H179N45O25Colore e forma:SolidPeso molecolare:2411.78Clathrin-IN-25
CAS:Clathrin-IN-25 is the most effective clathrin terminal domain-amphiphysin inhibitor reported to date.Formula:C19H13KNO5SColore e forma:SolidPeso molecolare:406.47MB 0223
CAS:DRP1 partial inhibitor (IC50 = 1.2 μM), selective over OPA1/DYN1, boosts mtDNA in mfn1-knockout MEFs.Formula:C26H27N5OSColore e forma:SolidPeso molecolare:457.59Drp1-IN-1
CAS:Drp1-IN-1 (comp A-7) is a Drp1 protein inhibitor (IC50: 0.91 μM).Formula:C22H24N8OSColore e forma:SolidPeso molecolare:448.544
