Telomerasi
La telomerasi è un enzima che aggiunge sequenze nucleotidiche ripetitive alle estremità dei cromosomi, note come telomeri, mantenendone così la lunghezza e proteggendoli dalla degradazione. L'attività della telomerasi è cruciale per la proliferazione indefinita delle cellule, in particolare nelle cellule staminali e nelle cellule tumorali. Gli inibitori della telomerasi sono di grande interesse nella ricerca sul cancro, poiché possono limitare il potenziale replicativo delle cellule tumorali, portando alla loro morte. Al contrario, gli attivatori della telomerasi sono esplorati per il loro potenziale nelle terapie anti-invecchiamento. Presso CymitQuimica, offriamo una selezione di inibitori e attivatori della telomerasi di alta qualità per supportare la tua ricerca in biologia del cancro, invecchiamento e immortalità cellulare.
Trovati 33 prodotti di "Telomerasi"
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TMPyP [Ultra-high sensitive spectrophotometric reagent for Cu, Mg] [For the simultaneous determination of metals by HPLC]
CAS:Formula:C72H66N8O12S4Purezza:>98.0%(N)Colore e forma:Dark red to Dark purple to Dark blue powder to crystalPeso molecolare:1,363.60(-)-Epigallocatechin Gallate Hydrate
CAS:Formula:C22H18O11·xH2OPurezza:>98.0%(HPLC)Colore e forma:White to Light yellow to Light orange powder to crystalPeso molecolare:458.38 (as Anhydrous)3'-Azido-3'-deoxythymidine
CAS:Formula:C10H13N5O4Purezza:>98.0%(T)Colore e forma:White to Almost white powder to crystalPeso molecolare:267.25Abacavir
CAS:Abacavir (Ziagen) is a nucleoside reverse transcriptase inhibitor analog of guanosine.Formula:C14H18N6OPurezza:99.36% - 99.81%Colore e forma:White PowderPeso molecolare:286.33Ref: TM-T1267
1g344,00€5mg35,00€10mg51,00€25mg77,00€50mg90,00€100mg115,00€200mg144,00€500mg234,00€1mL*10mM (DMSO)50,00€Thymidine, 2',3'-didehydro-3'-deoxy-
CAS:Formula:C10H12N2O4Purezza:98%Colore e forma:SolidPeso molecolare:224.2133Telomerase-IN-2
CAS:Telomerase-IN-2 (Telomerase inhibitor 2) shows potent inhibitory activity against telomerase by decreasing the expression of dyskerin (IC50: 0.89 µM).Formula:C34H39N3O9Purezza:99.32%Colore e forma:SolidPeso molecolare:633.69(2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3-yl 3,4,5-trihydroxybenzoate
CAS:Formula:C22H18O11Purezza:98%Colore e forma:SolidPeso molecolare:458.3717Ref: IN-DA00IK6L
1g22,00€5g24,00€10g31,00€1kg527,00€25g55,00€50g80,00€5kgPrezzo su richiesta100g114,00€250g177,00€500g302,00€Ceramides Mixture
CAS:Ceramides Mixture: endogenous, regulates cell cycle, growth, and telomerase activity, with hydroxy/non-hydroxy fatty acids.Formula:C36H71NO4Purezza:98%Colore e forma:SolidPeso molecolare:581.967Thymidine, 3'-azido-3'-deoxy-
CAS:Formula:C10H13N5O4Purezza:98%Colore e forma:SolidPeso molecolare:267.2413Ref: IN-DA0030EV
1g29,00€5g49,00€10g64,00€1kgPrezzo su richiesta25g120,00€50g181,00€100g201,00€250g554,00€MST-312
CAS:<p>MST-312, a telomerase inhibitor derived from green tea's EGCG, has research potential in cancer, including MM.</p>Formula:C20H16N2O6Purezza:99.61% - 99.68%Colore e forma:SolidPeso molecolare:380.35TRF1-TIN2 interaction-IN-1
TRF1-TIN2 interaction-IN-1 (Compound 40) is an inhibitor of the TRF1-TIN2 interaction. It binds to the TRFH domain of TRF1 (KD= 29 μM) and competitively inhibits the binding of the TIN2 peptide (IC50= 67 μM). By occupying a hotspot at the TRF1-TIN2 interface, TRF1-TIN2 interaction-IN-1 disrupts the interaction between TRF1 and TIN2. This compound can remove TRF1 from the shelterin complex, making it useful for research on shelterin-related cancers.Formula:C19H18O6SColore e forma:SolidPeso molecolare:374.41Tertomotide hydrochloride
CAS:<p>Tertomotide (GV1001) hydrochloride is a peptide vaccine composed of a 16-amino acid sequence from human telomerase reverse transcriptase (hTERT). It exhibits neuroprotective properties and has potential for research in Alzheimer's disease.</p>Formula:C85H147ClN26O21Colore e forma:SolidPeso molecolare:1904.69PIPER
CAS:Formula:C38H36N4O4Purezza:>95.0%(HPLC)Colore e forma:Red to Dark red to Dark purple powder to crystalPeso molecolare:612.73Pyridostatin Pentatrifluoroacetate
CAS:Formula:C31H32N8O5·5C2HF3O2Purezza:>95.0%(HPLC)(qNMR)Colore e forma:White to Light yellow powder to crystalPeso molecolare:1,166.76BIBR 1532
CAS:Formula:C21H17NO3Purezza:>95.0%(HPLC)(qNMR)Colore e forma:White to Light yellow powder to crystalPeso molecolare:331.37Epitalon
CAS:Epithalon (Epitalon) is a synthetic pineal peptide analog of epithalamin with potential applications in anti-aging and longevity research.Formula:C14H22N4O9Purezza:99.97%Colore e forma:SolidPeso molecolare:390.352',3'-Didehydro-3'-deoxythymidine
CAS:Formula:C10H12N2O4Purezza:>98.0%(T)(HPLC)Colore e forma:White to Almost white powder to crystalPeso molecolare:224.22BMVC
CAS:Formula:C28H25I2N3Purezza:>95.0%(HPLC)(qNMR)Colore e forma:Light yellow to Brown powder to crystalPeso molecolare:657.34BIBR 1532
CAS:<p>BIBR 1532 is an effective, specific and non-competitive telomerase inhibitor (IC50: 100 nM, in a cell-free assay).</p>Formula:C21H17NO3Purezza:98.49% - 98.90%Colore e forma:SolidPeso molecolare:331.36BCH001
CAS:BCH001 is a specific small-molecule inhibitor of PAPD5.Formula:C20H15F3N2O5Purezza:99.06%Colore e forma:SolidPeso molecolare:420.34TMPyP4 tosylate
CAS:<p>TMPyP4 tosylate (TMP 1363) is a quadruplex-specific ligand and is a telomerase inhibitor with antitumor effects in osteosarcoma cell lines.</p>Formula:C72H66N8O12S4Purezza:98.61% - 99.85%Colore e forma:SolidPeso molecolare:1363.6Abacavir sulfate
CAS:Abacavir sulfate (Ziagen) , a nucleoside analogue, effectively utilize its antiviral activityFormula:C14H18N6OH2O4SPurezza:99.79% - 99.85%Colore e forma:White To Off-White SolidPeso molecolare:335.38RHPS4
CAS:<p>RHPS4 (RHPS 4 methosulfate) is a potent inhibitor of Telomerase at submicromolar.</p>Formula:C22H17F2N2·CH3O4SPurezza:99.72%Colore e forma:SolidPeso molecolare:458.48360A
CAS:<p>360A is a stabilizing G-Quadruplex ligand, and also inhibits telomerase activity for telomerase in TRAP-G4 assay(IC50 : 300 nM).</p>Formula:C27H23N5O2Purezza:98.68%Colore e forma:SolidPeso molecolare:449.5Hypericin
CAS:Hypericin (Cyclosan) is a natural anthraquinone compound. Hypericin exhibits antimicrobial, antiviral, antitumor, and antidepressant effects. Cost-effective and quality-assured.Formula:C30H16O8Purezza:98.90% - ≥98%Colore e forma:Red-Coloured Anthraquinone-DerivativePeso molecolare:504.44Ref: TM-T6S0923
1mg57,00€5mg127,00€10mg182,00€25mg360,00€50mg532,00€100mg743,00€500mg1.510,00€1mL*10mM (DMSO)140,00€L-778123 hydrochloride
CAS:The L-778123 hydrochloride is an inhibitor of FPTase (IC50: 2 nM) and GGPTase-I (IC50: 98 nM) in enzyme inhibition determination.Formula:C22H21Cl2N5OPurezza:93.93% - 98.51%Colore e forma:SolidPeso molecolare:442.34Cycloastragenol
CAS:Cycloastragenol, a saponin from Astragalus, could be a new depression treatment.Formula:C30H50O5Purezza:99.85% - 99.92%Colore e forma:SolidPeso molecolare:490.71Remodelin hydrobromide
CAS:Remodelin hydrobromide (Remodelin HBR) is a novel potent and selective inhibitor of the acetyl-transferase protein NAT10.Formula:C15H15BrN4SPurezza:98% - 99.84%Colore e forma:SolidPeso molecolare:363.275Ref: TM-T6133
2mgPrezzo su richiesta5mg57,00€10mg87,00€25mg145,00€50mg249,00€100mg354,00€200mg528,00€1mL*10mM (DMSO)64,00€Antipsychotic agent 54
CAS:Telomerase-IN-1 is a telomerase inhibitor (IC50: 0.19 μM).Formula:C21H23FN2O4Purezza:98.10%Colore e forma:SolidPeso molecolare:386.42Ref: TM-T12009
1mg89,00€5mg187,00€10mg311,00€25mg530,00€50mg748,00€100mg1.064,00€1mL*10mM (DMSO)215,00€7-Deaza-2′-deoxyguanosine 5′-triphosphate
CAS:7-Deaza-2′-deoxyguanosine 5′-triphosphate (7-Deaza-2'-dGTP), a nucleotide analogue, functions as a telomerase inhibitor with an IC50 value of 11 μM [1].Formula:C11H17N4O13P3Purezza:98%Colore e forma:SolidPeso molecolare:506.19TERT activator-2
CAS:TERT activator-2 (Compound 1030) is an activator of telomerase reverse transcriptase (TERT), which enhances the expression levels of TERT within cells. TERT activator-2 is applicable to research related to cellular lifespan and telomere functions.Formula:C21H22N2O2Colore e forma:SolidPeso molecolare:334.412
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