Endocrinologia/Ormoni
Gli inibitori dell'endocrinologia/oromone sono composti che bloccano l'azione degli ormoni o interferiscono con le vie di segnalazione ormonale. Questi inibitori sono fondamentali per studiare la regolazione dei sistemi endocrini e per sviluppare trattamenti per malattie correlate agli ormoni, come il diabete, i disturbi della tiroide e i tumori ormono-dipendenti. Modulando l'attività ormonale, questi inibitori possono aiutare a chiarire le complesse interazioni all'interno del sistema endocrino. Presso CymitQuimica, offriamo un'ampia gamma di inibitori di alta qualità per endocrinologia/oromone per supportare le tue ricerche in endocrinologia, farmacologia e scienze mediche.
Sottocategorie di "Endocrinologia/Ormoni"
- Recettore degli androgeni(229 prodotti)
- Annessina A(16 prodotti)
- Aromatasi(22 prodotti)
- Recettore degli estrogeni/progestogeni(59 prodotti)
- GPR(1 prodotti)
- Recettore dei glucocorticoidi(166 prodotti)
- LHRH(2 prodotti)
- Recettore degli oppioidi(326 prodotti)
- Recettore della prostaglandina(122 prodotti)
- RAAS(90 prodotti)
- Riduttasi(50 prodotti)
- Somatostatina(57 prodotti)
- Recettore dell'ormone tiroideo (THR)(32 prodotti)
- Recettore della vasopressina(48 prodotti)
Mostrare 6 più sottocategorie
Trovati 3373 prodotti di "Endocrinologia/Ormoni"
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CI 992
CAS:CI 992 is a novel potent inhibitor of primate renin.Formula:C33H52N6O7S2Colore e forma:SolidPeso molecolare:708.93Androstatrione
CAS:<p>Androstatrione is an androgenic compound.</p>Formula:C19H26O3Colore e forma:SolidPeso molecolare:302.41ER degrader 10
CAS:<p>ER degrader 10 (Compound 51) is an orally active estrogen receptor (ER) selective degrader and antagonist, with a DC50 of 0.43 nM and an IC50 of 0.56 nM. It inhibits the proliferation of ER-positive cells, with an IC50 ranging from 0 to 15 nM. ER degrader 10 exhibits weak inhibitory activity on the hERG channel, with an IC50 greater than 40 μM. It has blood-brain barrier permeability, with a brain/plasma ratio (Kp) of 3.05. In mouse models, ER degrader 10 demonstrates antitumor activity.</p>Formula:C28H29F2NO3SColore e forma:SolidPeso molecolare:497.597Mu opioid receptor antagonist 5
Compound NAP: MOR antagonist, crosses blood-brain barrier, EC50: 1.14 nM, Ki: 0.37 nM, useful for OUD research.Formula:C26H29N3O4Colore e forma:SolidPeso molecolare:447.53PBPE hydrochloride
CAS:PBPE hydrochloride is a derivative of tamoxifen and functions as a selective ligand for antiestrogen binding sites (AEBS). The binding affinity (Ki) of PBPE hydrochloride and MBPE to AEBS is 8.79 nM and 17.57 nM, respectively.Formula:C19H24ClNOColore e forma:SolidPeso molecolare:317.853GPR84 antagonist 1
GPR84 antagonist 1 is a highly selective, high-affinity competitive antagonist of human GPR84.Formula:C26H22N4O2Colore e forma:SolidPeso molecolare:422.4821-Deacetoxy deflazacort
CAS:21-Deacetoxy deflazacort is a dehydrogenated derivative of Deflazacort, which is a glucocorticoid. As an inactive precursor, Deflazacort rapidly converts into the active metabolite, 21-Desacetyldeflazacort. This compound serves as both an anti-inflammatory and immunosuppressive agent.Formula:C23H29NO4Colore e forma:SolidPeso molecolare:383.48Metahexestrol
CAS:Metahexestrol is an inhibitor of the estrogen receptor (E2R) with antitumor activity. It significantly inhibits the proliferation of estrogen receptor-positive MCF-7 human breast cancer cell line with an ED50 of 1.0 μM. Additionally, Metahexestrol shows inhibitory activity in estrogen receptor-negative MDA-MB-231 cell lines, and its antiproliferative effect is not reversed by estrogen, suggesting that its mechanism may be partially independent of the E2R pathway. Metahexestrol is applicable in research on estrogen-dependent breast cancer.Formula:C18H22O2Colore e forma:SolidPeso molecolare:270.366Mopivabil
Mopivabil is the angiotensin II receptor antagonist[1].Formula:C14H20O3Colore e forma:SolidPeso molecolare:236.31Mepixetil
Mepixetil is a potent angiotensin II receptor antagonist[1].Formula:C12H18N2O3Colore e forma:SolidPeso molecolare:238.28Riminkefon
CAS:Riminkefon is a kappa opioid receptor agonist .Formula:C38H57N7O6Colore e forma:SolidPeso molecolare:707.9ADX61623
CAS:ADX61623 is an effective negative allosteric modulator (NAM) of the follicle-stimulating hormone receptor (FSHR). It also exhibits activity on the luteinizing hormone receptor (LH-R) but is inactive on the thyroid-stimulating hormone (TSH) receptor. ADX61623 can be utilized in research on estrogen-dependent diseases.Formula:C19H20N2O3Colore e forma:SolidPeso molecolare:324.37Mu opioid receptor antagonist 8
CAS:<p>Muopioid Receptor Antagonist 8 (368) serves as an antagonist to the μ-opioid receptor, significantly inhibiting the activation of Gi induced by met-enkephalin at the µOR.</p>Formula:C36H35N3O4SColore e forma:SolidPeso molecolare:605.75AKR1C3-IN-8
AKR1C3-IN-8 (Compound 5) is an effective and selective AKR1C3 inhibitor (IC50=0.069 μM). AKR1C3-IN-8 has antitumor activity.Formula:C23H20N4O3Colore e forma:SolidPeso molecolare:400.43GSK866
CAS:GSK866 is a selective glucocorticoid receptor agonist (SEGRA).Formula:C23H21Cl2F4N5O3Colore e forma:SolidPeso molecolare:562.34OT-R agonist 1 TFA
CAS:OT-R agonist 1 TFA (compound 5) is an oxytocin receptor (OT-R) agonist with an EC50 value of 0.39 nM. It exhibits V1A antagonist activity, with an EC50 value of 2432 nM, and can be utilized in studies related to central nervous system diseases.Formula:C37H40F3N7O7SColore e forma:SolidPeso molecolare:783.82Estrone acetate
CAS:Estrone acetate (Hogival) is an estrogen derivative and an activator of estrogen receptors (ER). This compound can enhance breast development, stimulate the secretion of pituitary prolactin, and induce both the proliferation and activation of lactotrophs, evidenced by the reduction in prolactin storage granule size and the increase in the volume density of the rough endoplasmic reticulum and Golgi apparatus. Estrone acetate holds potential for endocrinological research and for investigating the mechanisms by which estrogen influences pituitary function, prolactin regulation, and breast tumor models.Formula:C20H24O3Colore e forma:SolidPeso molecolare:312.403GW856464
CAS:GW856464 is an antagonist of MCHR1. It is utilized in research related to cardiovascular diseases and obesity.Formula:C23H20ClN3O3SColore e forma:SolidPeso molecolare:453.94rel-SB-612111 hydrochloride
CAS:NOP receptor antagonistFormula:C24H30Cl3NOPurezza:98%Colore e forma:SolidPeso molecolare:454.86ErSO-DFP
ErSO-DFP activates a-UPR, targets ERα+ cancer cells with high selectivity, and effectively reduces MCF-7 tumours.Formula:C20H17F5N2O2Colore e forma:SolidPeso molecolare:412.35SB-612111 hydrochloride
SB-612111 is a potent ORL-1 antagonist, with high affinity (Ki: 0.33 nM) and µ-receptor activity (Ki: 57.6 nM), blocking Nociceptin-induced pain.Formula:C24H30Cl3NOColore e forma:SolidPeso molecolare:454.86TRβ agonist 1
CAS:TRβ Agonist 1, a selective and mutation-sensitive thyroid hormone receptor β (TRβ) agonist, demonstrates an EC50 value of 21 nM.Formula:C29H25FN2O8Colore e forma:SolidPeso molecolare:548.52L 365209
CAS:L 365209 is an oxytocin antagonist.Formula:C40H50N8O6Purezza:98%Colore e forma:SolidPeso molecolare:738.88Phenethyl 4-ANPP
CAS:Phenethyl 4-ANPP is a MOR (μ-opioid receptor) agonist with a structure similar to known opioids.Formula:C27H32N2Colore e forma:SolidPeso molecolare:384.56KNT-127
CAS:KNT-127 is an agonist of δ-Opioid receptor.Formula:C24H24N2O2Purezza:98%Colore e forma:SolidPeso molecolare:372.46Estrogen receptor antagonist 7
CAS:ER antagonist 7, compound 13, inhibits ERs, halts breast/ovarian cancer cell growth, has anticancer properties.Formula:C23H17N3O4Colore e forma:SolidPeso molecolare:399.4Mu opioid receptor antagonist 3
Potent, selective MOR antagonist (compound 26); crosses blood-brain barrier. Ki: 0.24 nM, EC50: 0.54 nM; for studying OUD.Formula:C25H28N2O4SColore e forma:SolidPeso molecolare:452.57LXT34
CAS:LXT34 (Example 2) is a GPR120 agonist with anti-inflammatory properties. This compound enhances GLP-1 formation in the gastrointestinal tract and improves insulin resistance in macrophages and pancreatic cells. LXT34 is applicable in studies related to inflammatory conditions, such as type 2 diabetes, obesity, and non-alcoholic fatty liver disease.Formula:C18H21NO3SColore e forma:SolidPeso molecolare:331.43THR-β agonist 4
CAS:THR-β agonist 4 is a potent agonist of THR-β.Formula:C16H11Cl2F2N5O6SColore e forma:SolidPeso molecolare:510.26BU72
CAS:BU72 is a potent, long-lasting agonist for μ and κ opioid receptors, with partial agonistic activity at the δ opioid receptor (EC50 values of 0.054, 0.033, and 0.58 nM, respectively). It provides strong, enduring analgesic effects primarily mediated through μ opioid receptors. BU72 also exhibits a prolonged duration of activity and can partially reverse morphine-induced analgesia. It is applicable in studies of opioid dependence.Formula:C28H32N2O2Colore e forma:SolidPeso molecolare:428.57THR-β agonist 5
CAS:THR-β agonist 5 (compound 54) is a potent THR-β agonist, with an EC 50 of <50 nM [1].Formula:C22H23N5O2Colore e forma:SolidPeso molecolare:389.45(±)-J 113397
CAS:(±)-J-113397 is a potent and selective non-peptidyl ORL1 receptor antagonist (K(i): cloned human ORL1=1.8 nM).Formula:C24H37N3O2Colore e forma:SolidPeso molecolare:399.57KF-19418
CAS:KF-19418 is a follicle stimulant that directly activates follicles in vitro and promotes hair growth in vivo.Formula:C21H14N4OColore e forma:SolidPeso molecolare:338.36(E/Z)-OT-R antagonist 1
CAS:(E/Z)-OT-R antagonist 1 is a mixture of the E/Z configurations of OT-R antagonist 1. This compound is a novel, potent, selective, non-peptide OT-R antagonist that inhibits oxytocin-induced intracellular Ca2+ activity with an IC50 of 8 nM.Formula:C28H29N3O4Colore e forma:SolidPeso molecolare:471.55Ciprokiren
CAS:Ciprokiren, a renin inhibitor by Roche, halts human renin; IC50: 0.07/0.65 nmol/L. Lowers blood pressure in animals. Preclinical development ceased.Formula:C37H55N5O8SColore e forma:SolidPeso molecolare:729.93Androgen receptor antagonist 13
CAS:Androgen receptor antagonist 13 (compound 8a) is an orally active androgen receptor antagonist with an IC50 of 0.20 μM. It is used in prostate cancer research.Formula:C16H15N3O3SColore e forma:SolidPeso molecolare:329.37Mu opioid receptor antagonist 2
Compound 25: potent, selective MOR antagonist, crosses blood-brain barrier (Ki: 0.37 nM, EC50: 0.44 nM), for OUD research.Formula:C25H28N2O4SColore e forma:SolidPeso molecolare:452.57Androgen receptor ligand 1
CAS:Androgen receptorligand 1 is a ligand for the androgen receptor (AR). It interacts with the CRBN E3 ligase via a linker to form an AR-PROTAC degrader. This compound is useful in prostate cancer research.Formula:C19H16F4N2OColore e forma:SolidPeso molecolare:364.34GLPG0492 (R enantiomer)
CAS:GLPG0492 R enantiomer is the R enantiomer of GLPG-0492, a novel selective androgen receptor modulator.Formula:C19H14F3N3O3Colore e forma:SolidPeso molecolare:389.335α-Tetrahydrocorticosterone
CAS:5α-Tetrahydrocorticosterone (5α-HB) is an endogenous steroid that acts as an agonist of the glucocorticoid receptor (GR) and a metabolite of corticosterone. It serves as an effective topical anti-inflammatory agent in vivo. In rat liver cells, it decreases the binding of metabolites to the glucocorticoid receptor-corticosterone and its 5α-reduced metabolites, with a Kd value of 268 nM. 5α-Tetrahydrocorticosterone is applicable in research on inflammatory skin diseases.Formula:C21H34O4Colore e forma:SolidPeso molecolare:350.4922-Hydroxy mifepristone
CAS:22-Hydroxy Mifepristone (RU 42698) is an orally active hydroxylated alcohol metabolite that exhibits both anti-progestational and anti-glucocorticoid activities. This compound contains an alkyne group and is capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAC) with azide-containing molecules. Furthermore, 22-Hydroxy Mifepristone demonstrates a relative binding affinity of 48% to the human glucocorticoid receptor.Formula:C29H35NO3Colore e forma:SolidPeso molecolare:445.59Glucocorticoid receptor activator 1
CAS:Glucocorticoid Receptor Activator 1, a phenyl nitrogen-heterocyclic precursor, acts as an activator of the glucocorticoid receptor (GR). By activating GR, it downregulates the expression of pro-inflammatory genes stimulated by TNF, making it useful for inflammation research.Formula:C11H15Cl2NO2Colore e forma:SolidPeso molecolare:264.15ERα degrader 11
CAS:ERα degrader11 (compound B16) is a selective estrogen receptor degrader designed for use as a probe in examining the ER status within ER-positive breast cancer cells.Formula:C28H27F3N2O3Colore e forma:SolidPeso molecolare:496.52AVE 0991
CAS:AVE 0991 is a nonpeptide analog of angiotensin-(1-7), a Mas agonist with inhibitory effects on [125I]-Ang-(1-7) and on neuroinflammation in Alzheimer's disease.Formula:C29H32N4O5S2Purezza:99.73%Colore e forma:SolidPeso molecolare:580.72Amoitone B
CAS:Amoitone B, a cystosporone B derivative, functions as an NR4A1 agonist and exhibits anticancer activity [1].Formula:C22H34O5Colore e forma:SolidPeso molecolare:378.5MLS000389544
CAS:MLS000389544 is a selective and potent thyroid hormone receptor β (TRβ) antagonist with a methylsulfonyl nitrobenzoic acid structure. It effectively inhibits the interaction between TRβ and steroid receptor coactivator 2 (SRC2).Formula:C20H24N2O7SColore e forma:SolidPeso molecolare:436.479(Rac)-Fidarestat
CAS:(Rac)-Fidarestat ((Rac)-SNK 860) is the racemic form of Fidarestat, functioning as a potent inhibitor of the enzyme aldose reductase.Formula:C12H10FN3O4Colore e forma:SolidPeso molecolare:279.224AP5 sodium
CAS:AP5 sodium: potent oral GPR40 agonist, enhances ligands, may aid type II diabetes research.Formula:C28H27FNNaO4Colore e forma:SolidPeso molecolare:483.515AT1R antagonist 2
AT1R antagonist 2 is a potent AT1R selective ligand with good AT1R affinity (Ki: 26 nM).Formula:C29H37N5O4S2Colore e forma:SolidPeso molecolare:583.77Salvinorin A Propionate
CAS:Salvinorin A propionate: partial KOR agonist, Ki=32.6 nM, EC50=4.7 nM; ignores μ/δ/ORL-1, non-opioid receptors; less potent analgesic vs. salvinorin A.Formula:C24H30O8Colore e forma:SolidPeso molecolare:446.49PROTAC Androgen receptor degrader-1
CAS:PROTACAndrogen receptor degrader-1 (Ex.14) is a PROTAC degrader targeting the androgen receptor, with a DC50 of 6 nM. This compound is applicable in prostate cancer research.Formula:C43H48ClN9O2Colore e forma:SolidPeso molecolare:758.35TUG-2181
CAS:<p>TUG-2181 is an antagonist of GPR84, with an IC50 value of 34 nM. It inhibits reactive oxygen species (ROS) production and IL-8 secretion induced by GPR84 agonists in human neutrophils. TUG-2181 is applicable for research in inflammation and fibrosis.</p>Formula:C21H27NO4Colore e forma:SolidPeso molecolare:357.443Androgen receptor antagonist 11
CAS:Androgen receptor antagonist 11 (compound N29) is a selective, orally available antagonist.Formula:C20H19F3N4O3SColore e forma:SolidPeso molecolare:452.45Isotodesnitazene
CAS:Isotodesnitazene is an opioid compound that primarily targets the μ-opioid receptor (MOR). It exhibits EC50 values of 34.8 nM and 142 nM for MOR-βarr2 and MOR-mini-Gi, respectively. Isotodesnitazene can be utilized for research in opioid drugs.Formula:C23H31N3OColore e forma:SolidPeso molecolare:365.51GC 14
CAS:GC 14 is a selective thyroid hormone receptor antagonist, with IC50 values of 200 nM and 35 nM for hTRα and hTRβ, respectively.Formula:C26H27NO6Purezza:98%Colore e forma:SolidPeso molecolare:449.5LIT-001 free base
CAS:LIT-001, a nonpeptide OT-R agonist, enhances mouse autism-like behavior, with EC50=55 nM and Ki=226 nM.Formula:C28H33N7O2SPurezza:98%Colore e forma:SolidPeso molecolare:531.67Estrogen receptor modulator 11
CAS:Estrogen receptor modulator11 (Compound 27) is a tetrahydroisoquinoline derivative. It exhibits affinity for the estrogen receptor (ER), with IC50 values of 285 nM for ERα and 421 nM for ERβ. Estrogen receptor modulator11 does not demonstrate antagonist activity in MCF-7 cell assays.Formula:C21H18FNOColore e forma:SolidPeso molecolare:319.372Naltrindole 5′-isothiocyanate
CAS:Naltrindole 5′-isothiocyanate (5'-NTII) is an irreversible delta opioid receptor antagonist that counters the analgesic effects induced by DSLET without altering the effects caused by DPDPE.Formula:C27H25N3O3SColore e forma:SolidPeso molecolare:471.571GPR84 antagonist 3
CAS:Potent GPR84 antagonist 3 (compound 42), pIC50 8.28, inhibits GTPγS, with good pharmacokinetics.Formula:C29H27N5OColore e forma:SolidPeso molecolare:461.56BNTX
CAS:BNTX (7-Benzylidenenaltrexone) is a selective δ1-opioid receptor antagonist. It competitively counteracts the antisecretory effects of DPDPE, Deltorphin 2, and DAMGO. BNTX is applicable in research focused on antinociceptive effects.Formula:C27H27NO4Colore e forma:SolidPeso molecolare:429.508Sunobinop
CAS:Sunobinop (S 117957) is an opioid receptor-like orphan receptor (ORL1) modulator.Formula:C26H33N3O3Colore e forma:SolidPeso molecolare:435.56Sob-AM2
CAS:Sob-AM2 is an effective substrate targeting the fatty acid amide hydrolase (FAAH) expressed in the brain, with a Km of 1.3 μM. It delivers higher concentrations of Sobetirome to the central nervous system at minimal peripheral systemic doses, thereby activating the central thyroid hormone receptor β (TRβ).Formula:C21H27NO3Colore e forma:SolidPeso molecolare:341.44ERRα antagonist-2
CAS:ERRα antagonist-2 is an estrogen-related receptor α inverse agonist, inhibiting migration and invasion in ER-negative MDA-MB-231,breast cancer.Formula:C19H16N2O6SPurezza:99.26%Colore e forma:SolidPeso molecolare:400.41Androgen receptor antagonist 12
CAS:Compound EF2 (Androgen receptor antagonist 12) is an orally active antagonist of the androgen receptor (AR) with an IC50 of 0.30 µM. It inhibits the transcriptional activity of mutant AR and the proliferation of AR-positive PCa (prostate cancer) cell lines. Additionally, Compound EF2 blocks the nuclear translocation of AR and suppresses tumor growth in the C4-2B xenograft mouse model. This compound is used for research in prostate cancer.Formula:C12H8F3N3O2Colore e forma:SolidPeso molecolare:283.21Norbinaltorphimine dihydrochloride
CAS:Norbinaltorphimine dihydrochloride is a selective and potent κ opioid receptor antagonist that induces itch-associated responses in mice.Formula:C40H45Cl2N3O6Purezza:98.17% - 99.88%Colore e forma:SolidPeso molecolare:734.71Ref: TM-T12241
1mg38,00€5mg85,00€10mg120,00€25mg235,00€50mg409,00€100mg652,00€200mg908,00€1mL*10mM (DMSO)124,00€JDTic Dihydrochloride
CAS:JDTic Dihydrochloride is a high-affinity and selective κ-opioid receptor (KOR) antagonist that blocks dynorphin-KOR signalling,antidepressant.Formula:C28H41Cl2N3O3Purezza:98%Colore e forma:SolidPeso molecolare:538.55RX 809055AX
CAS:RX 809055AX is a long lasting opioid antagonist at mu and delta receptors.Formula:C29H29ClN2O4Colore e forma:SolidPeso molecolare:505CCG258747
CAS:CCG258747 is a novel, selective inhibitor of the GRK2 subfamily.Formula:C28H27FN4O4Colore e forma:SolidPeso molecolare:502.54Opioid receptor antagonist 1
CAS:<p>Opioid receptor antagonist 1 (Compound 10) is an Orvinol-based antagonist of opioid receptors. It exhibits activity as an antagonist against the analgesic properties of morphine.</p>Formula:C24H29ClF3NO4Colore e forma:SolidPeso molecolare:487.94NSC 645827
CAS:NSC 645827 is an inhibitor of NAD(P)H:quinone oxidoreductase 1 (NQO1), with an IC50 of 0.7 μM.Formula:C17H17N5O2Colore e forma:SolidPeso molecolare:323.349MK-6913
CAS:MK-6913 is a potent and selective agonist of estrogen receptor β.Formula:C25H27N3O2Purezza:98%Colore e forma:SolidPeso molecolare:401.5JTP-117968
CAS:JTP-117968: Non-steroidal SGRM, glucocorticoid receptor modulator, IC50 = 6.8 nM, offers better inhibitory/activatory balance.Formula:C31H31F3N2O2Colore e forma:SolidPeso molecolare:520.59Allyphenyline oxalate
CAS:<p>The pKi values of Allyphenyline oxalate (compound 9) for the α2-adrenergic receptor subtypes α2A, α2B, and α2C are 7.24, 6.47, and 7.07, respectively.</p>Formula:C16H20N2O5Colore e forma:SolidPeso molecolare:320.34EN171
CAS:EN171, a covalent ligand, selectively binds to C38 and C96 on 14-3-3, intensifying 14-3-3's interactions with ERα, YAP, and TAZ. This action impairs both estrogen receptor and Hippo pathway transcriptional activities. Beyond serving as a molecular glue to augment native protein interactions, EN171 also functions as a covalent recruiter for 14-3-3 in heterobifunctional molecules. This facilitates the sequestration of nuclear neo-substrates, such as BRD4 and BLC6, into the cytosol.Formula:C17H22N2OColore e forma:SolidPeso molecolare:270.37Elacestrant S enantiomer dihydrochloride
Elacestrant (RAD1901) dihydrochloride, an oral ERR degrader, has IC50 of 48 nM (ERα) and 870 nM (ERβ). Its S enantiomer has low activity.Formula:C30H40Cl2N2O2Purezza:98%Colore e forma:SolidPeso molecolare:531.56MB-07344 sodium
"MB-07344 sodium is a TR-β agonist with a 2.17 nM Ki, boosts Atorvastatin's cholesterol-lowering effects in various animals."Formula:C19H25NaO5PPurezza:98%Colore e forma:SolidPeso molecolare:387.36S-HP210
S-HP210: selective GR modulator, blocks NF-κB (IC50: 1.92 μM), non-toxic to mouse fibroblasts.Formula:C22H19N3O2S2Colore e forma:SolidPeso molecolare:421.54A 74273
CAS:A 74273, a nonpeptidic and renin inhibitor, may be used to treat cardiovascular diseases due to renin inhibition.Formula:C44H74N4O8Purezza:98%Colore e forma:SolidPeso molecolare:787.08GDC-0927 Racemate
CAS:GDC-0927 Racemate is a degrader of estrogen receptor, is used in the research of ER-related diseases, potently inhibits ER-α activity, with an IC50 of 0.2 nM.Formula:C28H28FNO4Purezza:98%Colore e forma:SolidPeso molecolare:461.52Bromadoline
CAS:Bromadoline is an opioid compound that exhibits anti-nociceptive properties in rodents.Formula:C15H21BrN2OColore e forma:SolidPeso molecolare:325.244Urotensin-II receptor antagonist-1
CAS:Urotensin-II receptor antagonist-1 (compound 1) is a human Urotensin II receptor antagonist with low oral bioavailability (F=0-3% in rats) and a Ki of 16 nM in HEK293 cells expressing human recombinant UT receptors. It inhibits cytochrome P450 enzymes (IC50=0.75 μM for CYP2D6; 1.4 μM for CYP3A4), suppresses κ opioid receptors (EC50=3.2 μM), and targets cardiac sodium channels (Ki=2.5 μM).Formula:C25H31Cl2N3OColore e forma:SolidPeso molecolare:460.439CH5447240
CAS:CH5447240: potent hPTHR1 agonist, treats Hypoparathyroidism, EC50 12 nM, 55% oral bioavailability, raises rat serum calcium.Formula:C26H39N5O4SPurezza:98%Colore e forma:SolidPeso molecolare:517.68BMS-248360
CAS:BMS-248360: Oral dual hAT1/hETA antagonist with Kis of 10nM & 1.9nM, respectively; treats hypertension.Formula:C36H45N5O5SPurezza:98%Colore e forma:SolidPeso molecolare:659.84ERβ agonist-1
CAS:ERβagonist-1 (Compound 8) functions as a dual-active selective ERβ agonist (EC50: 46.8 nM) and an AR antagonist (IC50: 1555 nM). By binding to ERβ, it activates its signaling pathways while simultaneously inhibiting AR activity. Retaining selective ERβ agonist activity in mouse models, ERβagonist-1 is applicable in prostate cancer research.Formula:C25H36O2Colore e forma:SolidPeso molecolare:368.55ID11916
CAS:ID11916 is an orally active compound functioning as both an androgen receptor (AR) antagonist and a phosphodiesterase 5 (PDE5) inhibitor. It disrupts androgen binding to AR, impedes nuclear translocation, and blocks androgen-dependent transcriptional activity of AR, while simultaneously elevating intracellular cGMP levels by inhibiting PKG activation. Moreover, ID11916 exhibits potent anticancer effects in prostate cancer cell lines VCaP and 22Rv1, as well as in AR-positive breast cancer cell line SK-BR-3.Formula:C29H27F3N8O3SColore e forma:SolidPeso molecolare:624.637AR antagonist 11
CAS:AR antagonist 11 (Compound c2) is a selective androgen receptor antagonist with an IC50 of 0.019 μM. It is also effective against the ARF877L/T878A mutant (IC50: 1.03 μM). Additionally, AR antagonist 11 inhibits LNCaP cell proliferation and decreases PSA protein expression (IC50: 0.54 μM). This compound is applicable in prostate cancer (PCa) research.Formula:C20H17ClN2OColore e forma:SolidPeso molecolare:336.815Fonsartan free acid
CAS:Fonsartan: Angiotensin receptor blocker, halts angiotensin II effects on rat vascular cells.Formula:C26H32N4O5S2Purezza:98%Colore e forma:SolidPeso molecolare:544.69Triisopropyl phosphate
CAS:Triisopropyl phosphate inhibits TFF1 and EGR3 gene expression and exhibits anti-estrogenic activity by suppressing Estradiol-induced proliferation of MCF-7 cells, with an EC50 of 341 μM. Additionally, Triisopropyl phosphate reduces estrogen response element (ERE)-stimulated luciferase activity in MVLN cells, with an EC50 of 900 μM.Formula:C9H21O4PColore e forma:SolidPeso molecolare:224.234Estrogen receptor antagonist 6
CAS:Estrogen receptor antagonist 6 is a potent blocker of estrogen signaling, regulating various biological effects. (Compound 166)Formula:C25H31F3N2O3Colore e forma:SolidPeso molecolare:464.52Naldemedine tosylate
CAS:Naldemedine (S-297995) tosylate, a PAMORA, targets μ-, δ-, κ-opioid receptors, aiding OIC research, may bind to SARS-CoV2's 3CL pro.Formula:C39H42N4O9SColore e forma:SolidPeso molecolare:742.84Anticancer agent 257
CAS:Anticanceragent 257 (compound of formula (I)) is an anticancer agent that regulates Nur77 and Nurr1.Formula:C15H9Cl2N3Colore e forma:SolidPeso molecolare:302.1585α-reductase-IN-1
CAS:5α-reductase-IN-1 is a potent inhibitor of the enzyme 5α-reductase.Formula:C31H37NO5Purezza:98%Colore e forma:SolidPeso molecolare:503.63BNTX maleate
CAS:δ1 opioid receptor antagonistFormula:C31H31NO8Purezza:98%Colore e forma:SolidPeso molecolare:545.58Mu opioid receptor antagonist 4
Compound 31: Potent, selective MOR antagonist; crosses blood-brain barrier; Ki & EC50: 0.38 nM; useful for OUD research.Formula:C25H28N2O4SColore e forma:SolidPeso molecolare:452.57BW 443C
CAS:BW 443C is a selective agonist of mu-opioid receptor.Formula:C33H46N10O10Colore e forma:SolidPeso molecolare:742.791DS69910557
DS69910557: potent hPTHR1 antagonist, IC50 0.08 μM, oral, for hyperparathyroidism & osteoporosis research.Formula:C32H33Cl2FN4O3Colore e forma:SolidPeso molecolare:611.53BU09059
CAS:BU09059 is a potent, selective, short-acting antagonist of the κ-opioid receptor (KOR).Formula:C28H37N3O5Purezza:98%Colore e forma:SolidPeso molecolare:495.61GNTI dihydrochloride
CAS:κ opioid receptor antagonistFormula:C27H30ClN5O3Purezza:98%Colore e forma:SolidPeso molecolare:508.01(+)-JJ-74-138
CAS:(+)-JJ-74-138 is a novel non-competitive androgen receptor (AR) antagonist capable of inhibiting enzalutamide-resistant castration-resistant prostate cancer (CRPC).Formula:C22H22F8N2OSColore e forma:SolidPeso molecolare:514.48RJG-2051
CAS:RJG-2051 is a selective covalent inhibitor of aldo-keto reductase family 1 member C3 (AKR1C3), with an IC50 value of 13 nM. It interferes with the metabolism of substrates such as androgens, estrogens, and prostaglandins through AKR1C3. RJG-2051 holds potential for cancer research.Formula:C26H31N5O4SColore e forma:SolidPeso molecolare:509.62C108297
CAS:C108297: glucocorticoid modulator, combats diet obesity/inflammation, reduces appetite/lipid storage, boosts fat burn.Formula:C30H36FN3O4SPurezza:98%Colore e forma:SolidPeso molecolare:553.69J-113397
CAS:J-113397 is a potent and selective NOP receptor antagonist (IC50 = 2.3 nM).Formula:C24H37N3O2Purezza:98%Colore e forma:SolidPeso molecolare:399.57BMS-986034
CAS:BMS-986034 is a GPR119 agonist.Formula:C24H24Cl2N6O4Colore e forma:SolidPeso molecolare:531.39LEO 134310
CAS:LEO 134310: Selective, non-steroidal GR agonist with 14 nM EC50, for topical skin disease treatment.Formula:C34H40N2O8Colore e forma:SolidPeso molecolare:604.69LNS8801
CAS:LNS8801 is an orally active agonist of the G protein-coupled estrogen receptor (GPER). By activating GPER, LNS8801 mediates downstream signaling pathways, such as promoting cAMP production and activating CREB signaling, which results in antitumor activities like inhibiting tumor cell proliferation, inducing cell differentiation, and enhancing tumor immunogenicity. It is applicable in research across various cancers, such as melanoma, pancreatic cancer, colorectal cancer, and lung cancer, as well as studies exploring the role of GPER in normal physiological and pathological processes.Formula:C21H18BrNO3Colore e forma:SolidPeso molecolare:412.277Dazucorilant
CAS:Dazucorilant (CORT113176), a selective non-steroidal GR modulator, has high affinity with a K i <1 nM, useful for neurological research.Formula:C29H22F4N4O3SColore e forma:SolidPeso molecolare:582.57PD 134922
CAS:PD 134922 is a HIV-1 protease inhibitors. Inactivation of the protease prevents infectious virion formation.Formula:C37H61N5O7SPurezza:98%Colore e forma:SolidPeso molecolare:719.97Galaxolide
CAS:Galaxolide can induce estrogenic activity (Estrogen Receptor/ERR), oxidative stress, and genotoxicity. It also stimulates the enzymatic activities of EROD and GST (Glutathione S-transferase).Formula:C18H26OColore e forma:SolidPeso molecolare:258.40Erα-IN-1
Erα-IN-1 (compound 3c) is an inhibitor of the estrogen receptor α (ERα), effectively blocking ERα activity in MCF7/ERE-LUC cells.Formula:C16H11FN2Colore e forma:SolidPeso molecolare:250.27SC13
CAS:SC13, a novel mitragynine analog, exhibits low-efficacy agonism at Mu opioid receptors and provides antinociception while minimizing adverse effects.Formula:C26H30N2O5Colore e forma:SolidPeso molecolare:450.53FSH receptor antagonist 1
CAS:FSH receptor antagonist 1 (compound 10) is a potent antagonist of the G(s) protein-coupled human follicle-stimulating hormone (FSH) receptor. It exhibits an IC50 value of 28 nM in cell lines expressing the human FSH receptor. This compound significantly inhibits follicle growth and ovulation in in vitro mouse models.Formula:C33H32N2O2Colore e forma:SolidPeso molecolare:488.619LY2066948
CAS:LY2066948 is a selective oral estrogen receptor modulator (SERM) with high affinity for estrogen receptors ERα and ERβ (Ki of 0.51 and 1.36 nM, respectively) and displays potent anti-estrogenic activity. It effectively blocks the increase in uterine weight induced by ethinylestradiol in immature rats. LY2066948 is utilized in the research of uterine fibroids and myomas.Formula:C30H31NO5SColore e forma:SolidPeso molecolare:517.64Daeatal
CAS:Dynorphin A ethylamide (1-9), the opioid activities were examined in the bioassays.Formula:C56H93N19O10Purezza:98%Colore e forma:SolidPeso molecolare:1192.4622-Thiocyanatosalvinorin A
CAS:22-Thiocyanatosalvinorin A (RB-64) is a potent selective agonist for the kappa-opioid receptor, exhibiting an EC50 value of 0.077 nM.Formula:C24H27NO8SColore e forma:SolidPeso molecolare:489.54EN1441
CAS:EN1441 is a covalent degrader that targets the androgen receptor (AR) with an EC50 value of 4.2 μM, as well as its truncated variant AR-V7. It selectively and effectively degrades AR and AR-V7 in androgen-independent prostate cancer cells. EN1441 holds potential for research into androgen-independent prostate cancer.Formula:C13H13ClN2O2Colore e forma:SolidPeso molecolare:264.708GPR81 agonist 2
CAS:GPR81 agonist 2 is a potent agonist targeting the GPR81 receptor, demonstrating EC50 values of 0.023 µM for hGPR81 and 0.123 µM for hGPR109A, respectively.Formula:C26H27ClN6O5S2Colore e forma:SolidPeso molecolare:603.11σ1 Receptor/μ Opioid receptor modulator 2
CAS:Compound 4x, also known as σ1 Receptor/μOpioid receptormodulator 2, acts as a μOR agonist and a σ1R antagonist, exhibiting a potent μOR EC50 of 0.6 nM and strong σ1R inhibitory activity (Ki: 363.7 nM). It demonstrates significant analgesic effects in various pain models.Formula:C23H31N3OPeso molecolare:365.51FL442
CAS:FL442 is an Androgen Receptor (AR) modulator. This compound exhibits potent inhibitory effects in AR-dependent prostate cancer cells, showing similar suppression efficiency to the traditional antiandrogen drugs Bicalutamide and Enzalutamide. It also maintains antiandrogen activity against the Enzalutamide-resistant AR mutant F876L. The pharmacokinetic properties of FL442 in mice reveal a longer half-life (8 hours), excellent targeting (prostate tissue), and metabolic stability. Additionally, it is effective at inhibiting LNCaP tumor growth at low plasma concentrations (30 ng/mL).Formula:C15H13F3N2OColore e forma:SolidPeso molecolare:294.27ERα degrader 5
ERα degrader 5 is an orally active, selective estrogen receptor (ER) reducer that acts on ERα (EC50: 1.1 nM). ERα degrader 5 shows anti-tumour effects in vivo.Formula:C29H25F4N3O2SColore e forma:SolidPeso molecolare:555.59TD-0212 TFA
CAS:TD-0212 TFA is an oral AT1 receptor antagonist & NEP inhibitor with pKi 8.9 & pIC50 9.2.Formula:C30H35F4N3O6SPurezza:98%Colore e forma:SolidPeso molecolare:641.67AKR1C3-IN-5
AKR1C3-IN-5 inhibits AKR1C3, key in prostate/breast cancers, with MCF-7 cell IC50 of 9.6 μM.Formula:C34H44N2O7Colore e forma:SolidPeso molecolare:592.72TD-0212
CAS:TD-0212: Oral dual antagonist for AT1 (pKi 8.9) & NEP inhibitor (pIC50 9.2).Formula:C28H34FN3O4SPurezza:98%Colore e forma:SolidPeso molecolare:527.65U 80215
CAS:U 80215 is an enzyme-competitive inhibitor.Formula:C42H60N8O6SColore e forma:SolidPeso molecolare:805.045′-Guanidinonaltrindole
CAS:5′-Guanidinonaltrindole (GNTI) is a selective antagonist of the kappa opioid receptor.Formula:C27H29N5O3Colore e forma:SolidPeso molecolare:471.551Saprisartan potassium
CAS:Saprisartan potassium is an Angiotensin II Type 1 receptor antagonist and antihypertensive agent.Formula:C25H21BrF3KN4O4SColore e forma:SolidPeso molecolare:649.52Emd 52297
CAS:Emd 52297 is an inhibitor of renin.Formula:C39H59N11O7Purezza:98%Colore e forma:SolidPeso molecolare:793.96MTI013
MTI013 is a selective inhibitor of SARS-CoV-2 nsp14 Mtase (IC50: 2.98 µM) and an antiviral agent (IC50: 10.33 µM in HCoV-229E infected Huh7 cells). Additionally, MTI013 demonstrates synergistic antiviral effects when used in conjunction with the RdRp inhibitor SHEN26.Formula:C24H26N6O4SColore e forma:SolidPeso molecolare:494.57NOP agonist-1
CAS:NOP agonist-1 (compound 4) is a nociceptin opioid receptor (NOP) partial agonist that attenuates Parkinsonian disabilities in 6-OHDA hemilesioned rats [1].Formula:C22H34N2Peso molecolare:326.52Win 45164
CAS:Win 45164 is an orally active ligand for the glucocorticoid receptor (Glucocorticoid Receptor), exhibiting activity that inhibits the pituitary-adrenal axis. It enhances liver glycogen deposition and thymolysis in adrenalectomized male rats. Additionally, Win 45164 possesses anti-inflammatory properties and is applicable in research related to inflammation and neurological disorders.Formula:C26H27FN2O2Peso molecolare:418.503Novokinin
CAS:Angiotensin AT2 receptor agonistFormula:C39H61N11O7Purezza:98%Colore e forma:SolidPeso molecolare:795.97SB-612111
CAS:SB-612111: potent ORL-1 antagonist, Ki=0.33 nM; μ-, κ-, δ-receptor Ki=57.6, 160.5, 2109 nM; blocks nociceptin's pain effect.Formula:C24H29Cl2NOColore e forma:SolidPeso molecolare:418.40SDM25N hydrochloride
CAS:δ receptor antagonistFormula:C26H27ClN2O3Purezza:98%Colore e forma:SolidPeso molecolare:450.96Androgen receptor degrader-5
CAS:Androgen receptor degrader-5 (compound 14k) demonstrates superior capabilities, specifically in androgen receptor degradation and antiproliferative activity, showcasing its promising properties.Formula:C29H25F4N5O2Colore e forma:SolidPeso molecolare:551.53AR ligand-44
CAS:AR ligand-44 is an androgen receptor (androgen receptor) ligand that can be utilized in the synthesis of PROTACs such as [ARD-2051].Formula:C23H24ClN3O2Colore e forma:SolidPeso molecolare:409.91AKR1C3-IN-7
AKR1C3-IN-7 (Compound 13) is an effective and selective AKR1C3 inhibitor (IC50=0.19 μM). AKR1C3-IN-7 has antitumor activity.Formula:C24H20N2O4Colore e forma:SolidPeso molecolare:400.43Pentomone
CAS:Pentomone (LY-113935) is an anti-androgen compound that acts as a prostate growth inhibitor.Formula:C24H26O5Colore e forma:SolidPeso molecolare:394.46AR antagonist 4
AR antagonist 4 (Compound 67-b) is an orally active androgen receptor (AR) antagonist that acts on wild-type AR (IC50: 246.6 nM).Formula:C29H36N4OColore e forma:SolidPeso molecolare:456.62Estrogen receptor-agonist-1
CAS:Estrogen receptor-agonist-1 (compound 4e) is an estrogen receptor (ER) agonist that binds to ERα with high affinity.Formula:C24H22N2O2Colore e forma:SolidPeso molecolare:370.444L162389
CAS:L162389 is an angiotensin II receptor antagonist with a balanced affinity for AT1 and AT2 receptor and stimulates the conversion of phosphatidylinositol.Formula:C31H38N4O4SPurezza:99.11% - 99.57%Colore e forma:SolidPeso molecolare:562.72OSU-ERb-12
CAS:OSU-ERb-12 is an ERβ agonist that suppresses ovarian cancer cell proliferation both in vitro and in vivo, and decreases the expression of Snail [1] [2].Formula:C15H30B10O2Colore e forma:SolidPeso molecolare:350.51ERRγ agonist-1
ERRγ agonist-1 can be used in neuropsychological disorders research.Formula:C17H21N5OColore e forma:SolidPeso molecolare:311.38ZD 7155 hydrochloride
CAS:ZD 7155 hydrochloride is an angiotensin II receptor type 1 (AT1 receptor) antagonist.Formula:C26H27ClN6OPurezza:99.8%Colore e forma:SolidPeso molecolare:474.98Ref: TM-T13390
1mg42,00€5mg88,00€10mg135,00€25mg235,00€50mg396,00€100mg635,00€200mg887,00€1mL*10mM (DMSO)90,00€L-371,257
CAS:L-371,257 is a competitive antagonist of oxytocin receptor with pA2 of 8.4 and Ki of 19 nM. L-371,257 shows a Ki of 3.7 nM for vasopressin receptor 1a.Formula:C28H33N3O6Purezza:99.79%Colore e forma:SolidPeso molecolare:507.58GLPG0974
CAS:GLPG0974 is an antagonist of FFA2/GPR43 with IC50 of 9 nM.Formula:C25H25ClN2O4SPurezza:99.8%Colore e forma:SolidPeso molecolare:484.99Cort108297
CAS:Cort108297: selective GR modulator/antagonist, high GR affinity (Ki: 0.45nM), no other steroid receptor affinity.Formula:C26H25F4N3O3SPurezza:98.36% - 99.94%Colore e forma:SolidPeso molecolare:535.55Ref: TM-T15000
1mg274,00€5mg622,00€10mg908,00€25mg1.415,00€50mg1.882,00€100mg2.745,00€1mL*10mM (DMSO)747,00€(E/Z)-GSK5182
CAS:GSK5182 is a racemic mix of (E/Z) isomers, a selective ERRγ inverse agonist (IC50: 79 nM), and induces ROS in liver cancer.Formula:C27H31NO3Purezza:97.58%Colore e forma:SolidPeso molecolare:417.54Ref: TM-T7709
1mg81,00€5mg170,00€10mg274,00€25mg502,00€50mg747,00€100mg1.121,00€1mL*10mM (DMSO)187,00€LSZ-102
CAS:LSZ-102 is an effective and selective degrader of estrogen receptor (IC50 = 0.2 nM) and can be used in studies about ERα positive breast cancer.Formula:C25H17F3O4SPurezza:98.56%Colore e forma:SolidPeso molecolare:470.46PSN632408
CAS:PSN632408 is an optimized agonist of GPR119 receptors that display similar potency to OEA at both recombinant mouse and human GPR119 receptors (EC50: 5.6 and 7.9 uM, respectively).Formula:C18H24N4O4Purezza:98%Colore e forma:SolidPeso molecolare:360.41ML314
CAS:ML314 is a brain-permeable nonpeptide β-inhibin-biased neurotensin NTR1 receptor agonist (EC50: 1.9 μM), a biased neurotensin receptor ligand for methamphetamine abuse that inhibits NTR2 and GPR35.Formula:C24H28N4O3Purezza:99.52%Colore e forma:SolidPeso molecolare:420.504(S)-Mapracorat
CAS:(S)-Mapracorat is a selective and less active agonist of the glucocorticoid receptor.Formula:C25H26F4N2O2Colore e forma:SolidPeso molecolare:462.48Mapracorat
CAS:Mapracorat (ZK-245186, BOL-303242X) is a selective glucocorticoid receptor agonist,anti-inflammatory agent for atopic dermatitis and allergic conjunctivitis.Formula:C25H26F4N2O2Colore e forma:SolidPeso molecolare:462.48Rat VLDL(Very Low Density Lipoprotein) ELISA Kit
<p>The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat VLDL. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat VLDL. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Rat VLDL, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Rat VLDL in the samples is then determined by comparing the OD of the samples to the standard curve.</p>Relacorilant
CAS:<p>Relacorilant is an oral glucocorticoid receptor antagonist with Ki of 7.2 nM, potential for treating Cushing's syndrome.</p>Formula:C27H22F4N6O3SPurezza:98.53% - 99%Colore e forma:SolidPeso molecolare:586.56Horse IGF1(Insulin Like Growth Factor 1) ELISA Kit
<p>The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Horse IGF1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Horse IGF1. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Horse IGF1, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Horse IGF1 in the samples is then determined by comparing the OD of the samples to the standard curve.</p>Mouse MDA(Malondialdehyde) ELISA Kit
<p>This assay employs the competitive inhibition enzyme immunoassay technique. The microtiter plate provided in this kit has been pre-coated with Mouse MDA protein. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse MDA. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Mouse MDA in the samples is then determined by comparing the OD of the samples to the standard curve.</p>Omzotirome
CAS:Omzotirome (TRC150094) is a functional analog of iodothyronines and holds potential for research on hyperlipidemia (WO2008149379).Formula:C19H24N2O3Colore e forma:SolidPeso molecolare:328.412Phosphoramidon Disodium
CAS:Phosphoramidon Disodium (Phosphoramidon Disodium Salt) Salt is a metalloendopeptidase inhibitor, widely used as a biochemical tool.Formula:C23H34N3Na2O10PPurezza:98%Colore e forma:SolidPeso molecolare:588.48GPR109 receptor agonist-2
CAS:Compound 5, a selective GPR109a agonist, exhibits a pEC50 value of 5.53 [1].Formula:C7H10N2O2Colore e forma:SolidPeso molecolare:154.17L-372662
CAS:L-372662 is bioactive chemical.Formula:C33H38N4O6Colore e forma:SolidPeso molecolare:586.68PF-998425
CAS:non-steroidal androgen receptor (AR) antagonistFormula:C14H14F3NOPurezza:98%Colore e forma:SolidPeso molecolare:269.2621-Acetoxypregna-1,4,9(11),16-tetraene-3,20-dione
21-Acetoxypregna-1,4,9(11),16-tetraene-3,20-dione is a valuable organic compound for life sciences research [Catalog No.: T67476, CAS No.: 37413-91-5].Formula:C23H26O4Colore e forma:SolidPeso molecolare:366.457ERB-196
CAS:Erb-196 is an estrogen receptor-receptor agonist with non-steroidal selectivity.Formula:C17H10FNO2Purezza:98%Colore e forma:SolidPeso molecolare:279.27AZD9496 maleate
CAS:AZD9496 maleate is a highly potent and selective antagonist of the estrogen receptor alpha (ERα), exhibiting an IC50 value of 0.28 nM. This compound, AZD9496 maleate, is an orally bioavailable selective estrogen receptor degrader (SERD).Formula:C29H29F3N2O6Colore e forma:SolidPeso molecolare:558.554Cebranopadol
CAS:<p>Cebranopadol (GRT6005) is an analgesic NOP and opioid receptor agonist with Kis of 0.9 nM, 0.7 nM, 2.6 nM, 18 nM for human NOP, μ-opioid (MOP), κ-opioid (KOP)</p>Formula:C24H27FN2OPurezza:98.32% - 99.78%Colore e forma:SolidPeso molecolare:378.48Pamoic acid
CAS:<p>Pamoic acid is the orphan G protein-coupled receptor GPR35 agonist. Pamoic acid activates ERK and beta-arrestin2 and causes antinociceptive activity.</p>Formula:C23H16O6Purezza:99.99%Colore e forma:Fine Yellow PowderPeso molecolare:388.37SR17018
CAS:<p>SR17018 is an mu-opioid-receptor (MOR) agonist, binding with GTPγS, with an EC50 of 97 nM.</p>Formula:C19H18Cl3N3OPurezza:99.89%Colore e forma:SolidPeso molecolare:410.72SR14150
CAS:SR14150 is a partial agonist of high-affinity NOP receptor.Formula:C21H30N2OPurezza:98%Colore e forma:SolidPeso molecolare:326.48Ref: TM-T24828
Prodotto fuori produzioneBromadoline maleate
CAS:Bromadoline is an opioid analgesic selective for the μ-opioid receptor.Formula:C19H25BrN2O5Purezza:98%Colore e forma:SolidPeso molecolare:441.322Ref: TM-T26908
Prodotto fuori produzioneCeronapril
CAS:Ceronapril (SQ 29852) is an orally active and potent angiotensin-converting enzyme (ACE) inhibitor (IC50 : 36 nM) for the study of dementia and hypertension.Formula:C21H33N2O6PPurezza:97.94%Colore e forma:SolidPeso molecolare:440.47Tirzepatide acetate
CAS:<p>Cymit Quimica provides this product solely for uses within the scope of any statute or law providing for an immunity, exemption, or exception to patent infringement (“Exempted Uses”), including but not limited to 35 U.S.C. § 271(e)(1) in the United States, the Bolar type exemption in Europe, and any corresponding exception to patent infringement in any other country. It is the sole responsibility of the purchaser or user of this product, and the purchaser or user of this product agrees to engage only in such Exempted Uses, and to comply with all applicable intellectual property laws and/or regulations. The purchaser of this product agrees to indemnify Cymit Quimica against all claims in connection with the performance of the respective commercial agreement (e.g. supply agreement) and possible infringements of intellectual property rights.</p>Purezza:Min. 95%Estrogen receptor modulator 8
CAS:<p>Estrogen Receptor Modulator 8 (compound 4) is an orally active inhibitor targeting Estrogen Receptor/ERR α with potent efficacy (IC50 = 0.437 nM in MCF-7 cells</p>Formula:C25H24F4N2O2Purezza:98%Colore e forma:SolidPeso molecolare:460.46MOR agonist-1
CAS:<p>MOR Agonist-1 is a μ-opioid receptor (MOR) agonist noted for its potent analgesic properties and is utilized in research concerning pain and associated</p>Formula:C22H26ClFN2O2Purezza:98%Colore e forma:SolidPeso molecolare:404.91ALS-I-41
CAS:ALS-I-41 is a novel, potent and selective antagonist of oxytocin receptor.Formula:C30H38FN3O6SPurezza:98%Colore e forma:SolidPeso molecolare:587.7Ref: TM-T26602
Prodotto fuori produzione
