Endocrinologia/Ormoni
Gli inibitori dell'endocrinologia/oromone sono composti che bloccano l'azione degli ormoni o interferiscono con le vie di segnalazione ormonale. Questi inibitori sono fondamentali per studiare la regolazione dei sistemi endocrini e per sviluppare trattamenti per malattie correlate agli ormoni, come il diabete, i disturbi della tiroide e i tumori ormono-dipendenti. Modulando l'attività ormonale, questi inibitori possono aiutare a chiarire le complesse interazioni all'interno del sistema endocrino. Presso CymitQuimica, offriamo un'ampia gamma di inibitori di alta qualità per endocrinologia/oromone per supportare le tue ricerche in endocrinologia, farmacologia e scienze mediche.
Sottocategorie di "Endocrinologia/Ormoni"
- Recettore degli androgeni(230 prodotti)
- Annessina A(16 prodotti)
- Aromatasi(23 prodotti)
- Recettore degli estrogeni/progestogeni(66 prodotti)
- GPR(1 prodotti)
- Recettore dei glucocorticoidi(165 prodotti)
- LHRH(2 prodotti)
- Recettore degli oppioidi(327 prodotti)
- Recettore della prostaglandina(126 prodotti)
- RAAS(89 prodotti)
- Riduttasi(51 prodotti)
- Somatostatina(57 prodotti)
- Recettore dell'ormone tiroideo (THR)(34 prodotti)
- Recettore della vasopressina(48 prodotti)
Mostrare 6 più sottocategorie
Trovati 3421 prodotti di "Endocrinologia/Ormoni"
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RLA-5331
RLA-5331: iron activator with anti-androgen properties; inhibits mCRPC cell proliferation.Formula:C40H43F3N6O7SColore e forma:SolidPeso molecolare:808.87PD 123177
CAS:PD 123177 is an inhibitor of Nonpeptide angiotensin AII-2.Formula:C29H28N4O3Purezza:98%Colore e forma:SolidPeso molecolare:480.56AKR1Cs-IN-1
AKR1Cs-IN-1 (Compound 29) is an effective and broad-spectrum inhibitor of the Aldo-Keto Reductase 1C family (AKR1C1-1C4). It achieves subtype inhibition by simultaneously binding to the SP2 and SP3 pockets, thereby blocking metabolic pathways related to drug resistance. In enzyme assays, AKR1Cs-IN-1 exhibits significant inhibitory activity with IC50 values of 0.09, 0.28, 0.05, and 0.51 µM for AKR1C1, AKR1C2, AKR1C3, and AKR1C4, respectively. The compound shows excellent resensitizing effects in doxorubicin (DOX)-resistant breast cancer cell line MCF-7/ADR, effectively enhancing the cytotoxicity of DOX. AKR1Cs-IN-1 holds promise for research on breast cancer resistance.Colore e forma:Odour SolidCIMBA hydrochloride
CIMBA hydrochloride is a selective antagonist of the G protein-coupled estrogen receptor (GPER). It can be utilized in research related to cholesterol gallstone disease in women.Colore e forma:Odour SolidPROTAC ER Degrader-11
CAS:PROTA CER Degrader-11 (Example 26-1) is an effective degrader of PROTA CER with an IC50 of 0.66 nM. It plays a crucial role in cancer research.Formula:C43H53N5O4Colore e forma:SolidPeso molecolare:703.91Tyr-W-MIF-1
CAS:Tyr-W-MIF-1, an opioid tetrapeptide, exhibits both opiate and antiopiate activities, and has been demonstrated to induce analgesia [1] [2] [5].Formula:C27H32N6O5Peso molecolare:520.58SR-29065
CAS:SR-29065 is a REV-ERBα agonist that represses BMAL1 transcription and is used to study circadian regulation, cancer, and autoimmune disease mechanisms.Formula:C24H24F6N2O2SPurezza:97.24% - 98.42%Colore e forma:Odour SolidPeso molecolare:518.524'-Hydroxytamoxifen TFA
4'-Hydroxytamoxifen TFA, a salt form of a metabolite of Tamoxifen, demonstrates higher affinity for ER compared to Tamoxifen itself. This compound induces non-apoptotic cytotoxicity in human endometrial adenocarcinoma cells.Formula:C28H30F3NO4Colore e forma:SolidPeso molecolare:501.54XOMA-213
XOMA-213 (LFA-102; X213) is a human monoclonal antibody (mAb) that specifically targets the PRLR/Prolactin Receptor. It inhibits hPRL-dependent growth of BaF3/hPRLR cells with an EC50 of 0.5 μg/mL. In models such as the Nb2-11-luc xenograft mouse and the DMBA-induced rat breast cancer model, XOMA-213 effectively suppresses PRLR signaling and tumor growth. This compound is applicable in research focused on breast cancer, hyperprolactinemia, and prostate cancer.ERD-1233
ERD-1233 is an effective oral PROTAC degrader of the estrogen receptor (estrogen receptor) with a DC50 of 0.9 nM. It plays a crucial role in research involving ER+ breast cancer.Formula:C49H53N5O6Colore e forma:SolidPeso molecolare:807.98[Orn8]-Urotensin II
CAS:[Orn8]-Urotensin II is a Urotensin receptor ligand and a partial agonist at Urotensin receptors.Formula:C63H83N13O18S2Colore e forma:SolidPeso molecolare:1374.5517-Epiestriol
CAS:17-Epiestriol, metabolite of estrone, forms via 16α-hydroxy intermediate and binds ERα and ERβ with affinity less than 17β-estradiol.Formula:C18H24O3Purezza:99.72%Colore e forma:SolidPeso molecolare:288.38Estetrol
CAS:Estetrol (Donesta), a fetal liver-synthesized estrogen, selectively modulates estrogen receptors and may ease menopausal symptoms.Formula:C18H24O4Purezza:99.93%Colore e forma:SolidPeso molecolare:304.38Ref: TM-T15248
1mg39,00€5mg84,00€1mL*10mM (DMSO)93,00€10mg130,00€25mg268,00€50mg462,00€100mg773,00€200mg1.044,00€Emd 55068
CAS:Emd 55068 is a synthetic antagonist of renin.Formula:C41H65N9O6Colore e forma:SolidPeso molecolare:780.01(S)-CVN424
CAS:(S)-CVN424 modulates GPR6, key for neurological/psychiatric research, including Parkinson's.Formula:C24H29F2N5O3Colore e forma:SolidPeso molecolare:473.525(d(CH2)51,Tyr(Me)2,Orn8)-Oxytocin
CAS:(d(CH2)51,Tyr(Me)2, Orn8)-Oxytocin (OVT) is an antagonist of the oxytocin receptor that finds application in the study of neurological diseases [1].Formula:C48H74N12O12S2Purezza:98%Colore e forma:SolidPeso molecolare:1075.3Deltorphin acetate
Deltorphin acetate is a substance obtained from the skin secretions of a frog, Phyllomedusa bicolor and shows high selectivity and affinity for δ-opioidFormula:C46H66N10O12S2Purezza:98.93%Colore e forma:SolidPeso molecolare:1015.21Ref: TM-T20166L
1mg175,00€5mg394,00€10mg590,00€25mg1.060,00€50mg1.591,00€100mg2.387,00€200mg3.580,00€6α-Methylprednisolone 21-hemisuccinate sodium salt
CAS:6α-Methylprednisolone 21-hemisuccinate sodium salt (Asmacortone), a water-soluble ester, is used for allergic, cardiac, and hypoxic emergencies.Formula:C26H33NaO8Purezza:99.65%Colore e forma:Lyophilized PowderPeso molecolare:496.53Leumorphin, human
CAS:Leumorphin, human, is a potent agonist of the kappa opioid receptor (κ opioid receptor) and inhibits the contraction of the guinea pig ileum's myenteric plexus-Formula:C150H224N42O46Purezza:98%Colore e forma:SolidPeso molecolare:3351.64AH 7563
CAS:AH 7563 is structurally classified as an opioid compound with analgesic properties. In mice, its ED50 for pain relief was 15.3 mg/kg when administered orally in the Phenylquinone test, and 15.5 mg/kg when injected subcutaneously in the Hot plate test.Formula:C16H24N2OColore e forma:SolidPeso molecolare:260.38
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