Endocrinologia/Ormoni
Gli inibitori dell'endocrinologia/oromone sono composti che bloccano l'azione degli ormoni o interferiscono con le vie di segnalazione ormonale. Questi inibitori sono fondamentali per studiare la regolazione dei sistemi endocrini e per sviluppare trattamenti per malattie correlate agli ormoni, come il diabete, i disturbi della tiroide e i tumori ormono-dipendenti. Modulando l'attività ormonale, questi inibitori possono aiutare a chiarire le complesse interazioni all'interno del sistema endocrino. Presso CymitQuimica, offriamo un'ampia gamma di inibitori di alta qualità per endocrinologia/oromone per supportare le tue ricerche in endocrinologia, farmacologia e scienze mediche.
Sottocategorie di "Endocrinologia/Ormoni"
- Recettore degli androgeni(229 prodotti)
- Annessina A(16 prodotti)
- Aromatasi(23 prodotti)
- Recettore degli estrogeni/progestogeni(66 prodotti)
- GPR(1 prodotti)
- Recettore dei glucocorticoidi(164 prodotti)
- LHRH(2 prodotti)
- Recettore degli oppioidi(327 prodotti)
- Recettore della prostaglandina(122 prodotti)
- RAAS(89 prodotti)
- Riduttasi(51 prodotti)
- Somatostatina(57 prodotti)
- Recettore dell'ormone tiroideo (THR)(34 prodotti)
- Recettore della vasopressina(48 prodotti)
Mostrare 6 più sottocategorie
Trovati 3419 prodotti di "Endocrinologia/Ormoni"
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Estrone acetate
CAS:Estrone acetate (Hogival) is an estrogen derivative and an activator of estrogen receptors (ER). This compound can enhance breast development, stimulate the secretion of pituitary prolactin, and induce both the proliferation and activation of lactotrophs, evidenced by the reduction in prolactin storage granule size and the increase in the volume density of the rough endoplasmic reticulum and Golgi apparatus. Estrone acetate holds potential for endocrinological research and for investigating the mechanisms by which estrogen influences pituitary function, prolactin regulation, and breast tumor models.Formula:C20H24O3Colore e forma:SolidPeso molecolare:312.403ORIC-101
CAS:ORIC-101 is a highly effective and selective glucocorticoid receptor antagonist (EC50: 5.6 nM). It also has anti-cancer activity.Formula:C34H47NO2Purezza:98%Colore e forma:SolidPeso molecolare:501.74Estrogen receptor antagonist 4
CAS:Estrogen receptor antagonist 4 blocks ER, impacting cell growth and cancer research potential.Formula:C23H29BF4N4O2Colore e forma:SolidPeso molecolare:480.31Androstatrione
CAS:Androstatrione is an androgenic compound.Formula:C19H26O3Colore e forma:SolidPeso molecolare:302.41Metahexestrol
CAS:Metahexestrol is an inhibitor of the estrogen receptor (E2R) with antitumor activity. It significantly inhibits the proliferation of estrogen receptor-positive MCF-7 human breast cancer cell line with an ED50 of 1.0 μM. Additionally, Metahexestrol shows inhibitory activity in estrogen receptor-negative MDA-MB-231 cell lines, and its antiproliferative effect is not reversed by estrogen, suggesting that its mechanism may be partially independent of the E2R pathway. Metahexestrol is applicable in research on estrogen-dependent breast cancer.Formula:C18H22O2Colore e forma:SolidPeso molecolare:270.366GC 14
CAS:GC 14 is a selective thyroid hormone receptor antagonist, with IC50 values of 200 nM and 35 nM for hTRα and hTRβ, respectively.Formula:C26H27NO6Purezza:98%Colore e forma:SolidPeso molecolare:449.5LIT-001 free base
CAS:LIT-001, a nonpeptide OT-R agonist, enhances mouse autism-like behavior, with EC50=55 nM and Ki=226 nM.Formula:C28H33N7O2SPurezza:98%Colore e forma:SolidPeso molecolare:531.67Norbinaltorphimine dihydrochloride
CAS:Norbinaltorphimine dihydrochloride is a selective and potent κ opioid receptor antagonist that induces itch-associated responses in mice.Formula:C40H45Cl2N3O6Purezza:98.17% - 99.88%Colore e forma:SolidPeso molecolare:734.71Ref: TM-T12241
1mg35,00€5mg80,00€10mg114,00€1mL*10mM (DMSO)117,00€25mg224,00€50mg388,00€100mg618,00€200mg859,00€Androgen receptor ligand 1
CAS:Androgen receptorligand 1 is a ligand for the androgen receptor (AR). It interacts with the CRBN E3 ligase via a linker to form an AR-PROTAC degrader. This compound is useful in prostate cancer research.Formula:C19H16F4N2OColore e forma:SolidPeso molecolare:364.34Opioid receptor antagonist 1
CAS:Opioid receptor antagonist 1 (Compound 10) is an Orvinol-based antagonist of opioid receptors. It exhibits activity as an antagonist against the analgesic properties of morphine.
Formula:C24H29ClF3NO4Colore e forma:SolidPeso molecolare:487.94OT-R agonist 1 TFA
CAS:OT-R agonist 1 TFA (compound 5) is an oxytocin receptor (OT-R) agonist with an EC50 value of 0.39 nM. It exhibits V1A antagonist activity, with an EC50 value of 2432 nM, and can be utilized in studies related to central nervous system diseases.Formula:C37H40F3N7O7SColore e forma:SolidPeso molecolare:783.82CH5447240
CAS:CH5447240: potent hPTHR1 agonist, treats Hypoparathyroidism, EC50 12 nM, 55% oral bioavailability, raises rat serum calcium.Formula:C26H39N5O4SPurezza:98%Colore e forma:SolidPeso molecolare:517.68ERβ agonist-1
CAS:ERβagonist-1 (Compound 8) functions as a dual-active selective ERβ agonist (EC50: 46.8 nM) and an AR antagonist (IC50: 1555 nM). By binding to ERβ, it activates its signaling pathways while simultaneously inhibiting AR activity. Retaining selective ERβ agonist activity in mouse models, ERβagonist-1 is applicable in prostate cancer research.Formula:C25H36O2Colore e forma:SolidPeso molecolare:368.55ID11916
CAS:ID11916 is an orally active compound functioning as both an androgen receptor (AR) antagonist and a phosphodiesterase 5 (PDE5) inhibitor. It disrupts androgen binding to AR, impedes nuclear translocation, and blocks androgen-dependent transcriptional activity of AR, while simultaneously elevating intracellular cGMP levels by inhibiting PKG activation. Moreover, ID11916 exhibits potent anticancer effects in prostate cancer cell lines VCaP and 22Rv1, as well as in AR-positive breast cancer cell line SK-BR-3.Formula:C29H27F3N8O3SColore e forma:SolidPeso molecolare:624.637AR antagonist 11
CAS:AR antagonist 11 (Compound c2) is a selective androgen receptor antagonist with an IC50 of 0.019 μM. It is also effective against the ARF877L/T878A mutant (IC50: 1.03 μM). Additionally, AR antagonist 11 inhibits LNCaP cell proliferation and decreases PSA protein expression (IC50: 0.54 μM). This compound is applicable in prostate cancer (PCa) research.Formula:C20H17ClN2OColore e forma:SolidPeso molecolare:336.81522-Hydroxy mifepristone
CAS:22-Hydroxy Mifepristone (RU 42698) is an orally active hydroxylated alcohol metabolite that exhibits both anti-progestational and anti-glucocorticoid activities. This compound contains an alkyne group and is capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAC) with azide-containing molecules. Furthermore, 22-Hydroxy Mifepristone demonstrates a relative binding affinity of 48% to the human glucocorticoid receptor.Formula:C29H35NO3Colore e forma:SolidPeso molecolare:445.59LEO 134310
CAS:LEO 134310: Selective, non-steroidal GR agonist with 14 nM EC50, for topical skin disease treatment.Formula:C34H40N2O8Colore e forma:SolidPeso molecolare:604.69GW856464
CAS:GW856464 is an antagonist of MCHR1. It is utilized in research related to cardiovascular diseases and obesity.Formula:C23H20ClN3O3SColore e forma:SolidPeso molecolare:453.94EN1441
CAS:EN1441 is a covalent degrader that targets the androgen receptor (AR) with an EC50 value of 4.2 μM, as well as its truncated variant AR-V7. It selectively and effectively degrades AR and AR-V7 in androgen-independent prostate cancer cells. EN1441 holds potential for research into androgen-independent prostate cancer.Formula:C13H13ClN2O2Colore e forma:SolidPeso molecolare:264.708GSK866
CAS:GSK866 is a selective glucocorticoid receptor agonist (SEGRA).Formula:C23H21Cl2F4N5O3Colore e forma:SolidPeso molecolare:562.34
