Recettore dell'ormone tiroideo (THR)
I recettori degli ormoni tiroidei (THR) sono recettori nucleari che mediano gli effetti degli ormoni tiroidei, cruciali per la regolazione del metabolismo, della crescita e dello sviluppo. La modulazione dell'attività dei THR è importante nel trattamento dei disturbi tiroidei, delle sindromi metaboliche e di alcuni tipi di cancro. Gli agonisti e antagonisti dei THR sono utilizzati nella ricerca per studiare i ruoli fisiologici e patologici degli ormoni tiroidei. Presso CymitQuimica, offriamo una vasta gamma di modulatori dei recettori degli ormoni tiroidei di alta qualità per supportare la tua ricerca in endocrinologia, metabolismo e regolazione ormonale.
Trovati 30 prodotti di "Recettore dell'ormone tiroideo (THR)"
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3,5-Diiodothyropropionic acid
CAS:3,5-Diiodothyropropionic acid: thyroid hormone analog, boosts α-myosin mRNA, binds TRα1 & TRβ1 (Ka: 2.40/M, 4.06/M).Formula:C15H12I2O4Purezza:98.42%Colore e forma:SolidPeso molecolare:510.06PCO371
CAS:PCO371 (2,4-Imidazolidinedione, 1-(3,5-dimethyl-4-(2-((4-oxo-2-(4-(trifluoromethoxy)phenyl)-1,3,8-triazaspiro(4.5)dec-1-en-8-yl)sulfonyl)ethyl)phenyl)-5,5-Formula:C29H32F3N5O6SPurezza:97.17% - 99.25%Colore e forma:SolidPeso molecolare:635.65pTH-Related Protein (1-34) amide (human, mouse, rat)
CAS:Human PTHrP-(1-34)NH2, also known as PTH-Related Protein (1-34) amide for human, mouse, and rat, is the N-terminal fragment of PTHrP.Trh-gly
CAS:TRH-glycine (TRH-gly) serves as a precursor to thyrotropin-releasing hormone (TRH), capable of inducing the release of thyrotropin (TSH) and prolactin [1].Formula:C18H24N6O6Peso molecolare:420.42Osteostatin
CAS:Osteostatin, derived from parathyroid hormone-related protein (PTHrP) 107-111, has demonstrated properties conducive to bone repair in animal models presentingFormula:C27H41N9O8Colore e forma:SolidPeso molecolare:619.67DPC-AJ1951 TFA
DPC-AJ1951 TFA is a 14 amino acid peptide, potent PTH/PPR agonist, tested in bone resorption assays.Formula:C78H128F3N23O21Colore e forma:SolidPeso molecolare:1781.02Human PTHrP-(1-36)
CAS:Human PTHrP-(1-36) is a secreted form of parathyroid hormone-related protein that exhibits anticalciuric effects and promotes beta cell function andFormula:C191H305N59O52Peso molecolare:4259.83Calcitonin, eel
CAS:<p>Calcitonin from eel regulates calcium and is key in studying postmenopausal osteoporosis.</p>Formula:C146H241N43O47S2Purezza:98%Colore e forma:White PowderPeso molecolare:3414.91NH-3
CAS:<p>NH-3, an orally active THR antagonist with a 55 nM IC50, blocks thyroid hormone binding and cofactor recruitment.</p>Formula:C28H27NO6Purezza:97.79% - 99.40%Colore e forma:SolidPeso molecolare:473.52Parathyroid hormone (1-34) (rat)
CAS:Parathyroid hormone (PTH) receptor agonist. Increases serum PTH levels and bone mass in rats.Formula:C180H291N55O48S2Purezza:98%Colore e forma:SolidPeso molecolare:4057.74DPC-AJ1951
CAS:Potent 14 amino acid peptide agonist of the parathyroid hormone (PTH) receptor (EC50 = 26 nM).Formula:C76H127N23O19Purezza:98%Colore e forma:SolidPeso molecolare:1666.98Osteostatin (1-5) amide (human, bovine, dog, horse, mouse, rabbit, rat)
CAS:Osteostatin (1-5) amide (human, bovine, dog, horse, mouse, rabbit, rat), also known as Human PTHrP (107-111) amide, is a C-terminal fragment of parathyroidFormula:C27H42N10O7Peso molecolare:618.69Prepro-TRH-(160-169)
CAS:Prepro-TRH-(160-169), a pro-TRH peptide, enhances TRH-stimulated TSH secretion.Formula:C54H75N11O18SColore e forma:SolidPeso molecolare:1198.3THR-β agonist 2 diacetate
THR-β agonist 2 diacetate (Compound 3) is a potent THR-β agonist with potential applications in researching metabolic disorders such as obesity, hyperlipidemia, hypercholesterolemia, and diabetes, as well as other conditions like steatosis and non-alcoholic steatohepatitis (NASH), atherosclerosis, and other related diseases and conditions.Colore e forma:Odour SolidHuman PTH-(1-31) amide
CAS:Human PTH-(1-31) amide, an analog of PTH, effectively stimulates phosphatidylcholine hydrolysis and promotes the release of adenylyl cyclase [1].Formula:C162H270N50O46S2Peso molecolare:3718.31(D-Trp12,Tyr34)-pTH (7-34) amide (bovine) acetate
D-Trp12,Tyr34-pTH(7-34) (bovine) is a PTH antagonist with a Ki of 69 nM in bovine kidneys.Purezza:96.84%Colore e forma:LiquidPeso molecolare:N/AResmetirom
CAS:<p>Resmetirom (MGL-3196) is a THR-β agonist (EC50=0.21 μM), with high selectivity and oral activity. High-Quality, Low-Cost!</p>Formula:C17H12Cl2N6O4Purezza:99.05% - >99.99%Colore e forma:SolidPeso molecolare:435.22REVERSE T3
CAS:<p>Reverse T3 (3,3',5'-triiodo-L-thyronine) inhibits the increase of sodium current generated by other thyroid hormone analogs in neonatal rat myocytes.</p>Formula:C15H12I3NO4Purezza:95.99% - 97.89%Colore e forma:PowderPeso molecolare:650.97Eprotirome
CAS:Eprotirome (KB2115), a synthetic thyroid hormone mimetic, is a thyroid hormone receptor agonist.Formula:C18H17Br2NO5Purezza:98.42% - 98.56%Colore e forma:SolidPeso molecolare:487.14Sobetirome
CAS:Sobetirome (IACS-010759) is a selective agonist of thyroid hormone receptor β (TRβ) and binds selectively to TRβ-1 (EC50: 0.16 μM).Formula:C20H24O4Purezza:98.08% - 98.25%Colore e forma:SolidPeso molecolare:328.43,3',5-Triiodothyronine-(tyrosine ring-13C6)
CAS:<p>3,3',5-Triiodothyronine-(tyrosine ring-13C6) is the 13C labeled compound of 3,3',5-Triiodothyronine. 3,3',5-Triiodothyronine has a CAS number of 5817-39-0.</p>Formula:C4C11H12I3NO4Colore e forma:SolidPeso molecolare:656.93Azetirelin
CAS:Azetirelin, as a TRH analog, has a more potent effect than TRH on the central nervous system.Formula:C15H20N6O4Purezza:99.72%Colore e forma:SolidPeso molecolare:348.36KAT681
CAS:KAT681 is a liver selective thyromimetic.Formula:C24H22FNNaO6Purezza:98%Colore e forma:SolidPeso molecolare:462.429Glutaurine aceate
Glutaurine aceate containing glutamine and taurine residues is an orally active hormone of the parathyroid.Formula:C9H18N2O8SPurezza:98%Colore e forma:SoildPeso molecolare:314.31TR antagonist 1
CAS:TR antagonist 1 is a highly potent thyroid hormone receptor (TR) antagonist that can be used to study diseases caused by endocrine abnormalities.Formula:C25H23Br2NO4Purezza:99.57%Colore e forma:SolidPeso molecolare:561.26MB-07344
CAS:MB-07344 is a selective THR-β (thyroid hormone receptor β) agonist with a Ki of 2.17 nM, capable of reducing plasma total cholesterol (TPC).Formula:C19H25O5PPurezza:99.32%Colore e forma:SolidPeso molecolare:364.37MB-07811
CAS:<p>MB-07811 (VK-2809) is an orally active HepDirect prodrug of MB07344 with cholesterol and triglycerides lowering activity.</p>Formula:C28H32ClO5PPurezza:99.74% - 99.94%Colore e forma:SolidPeso molecolare:514.98DS08210767
CAS:<p>DS08210767 is a highly potent, orally bioavailable PTHR1 antagonist with IC50 of 90 nM.</p>Formula:C31H39N5O2Purezza:98.79%Colore e forma:SolidPeso molecolare:513.67CO23
CAS:<p>CO23 is a blood-brain barrier penetrant and selective TRα agonist and can be used in studies about the regulation of growth and development.</p>Formula:C19H18I2N2O4Purezza:98.08%Colore e forma:SolidPeso molecolare:592.17MLS000389544
CAS:MLS000389544 is a selective and potent thyroid hormone receptor β (TRβ) antagonist with a methylsulfonyl nitrobenzoic acid structure. It effectively inhibits the interaction between TRβ and steroid receptor coactivator 2 (SRC2).Formula:C20H24N2O7SColore e forma:SolidPeso molecolare:436.479
