RAAS
Gli inibitori del sistema renina-angiotensina-aldosterone (RAAS) sono composti che prendono di mira la via del RAAS, nota principalmente per il suo ruolo nella regolazione della pressione sanguigna e dell'equilibrio dei fluidi, ma che influenza anche l'angiogenesi. La via del RAAS può contribuire allo sviluppo di nuovi vasi sanguigni nei tumori, supportandone così la crescita. Inibire i componenti del RAAS può quindi avere effetti anti-angiogenici, rendendo questi inibitori preziosi nel trattamento di alcuni tumori e disturbi vascolari. Presso CymitQuimica, offriamo una gamma di inibitori di alta qualità del RAAS per supportare la tua ricerca in biologia cardiovascolare, oncologia e angiogenesi.
Trovati 90 prodotti di "RAAS"
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H-Val-Pro-Pro-OH
CAS:H-Val-Pro-Pro-OH is an inhibitor of Angiotensin I converting enzyme (ACE)( IC50 : 9 μM).Formula:C15H25N3O4Purezza:98.23%Colore e forma:SolidPeso molecolare:311.38Valsartan
CAS:Valsartan (CGP 48933) is a tetrazole derivative and angiotensin II type 1 receptor blocker that is used to treat hypertension.Formula:C24H29N5O3Purezza:99.56% - 99.76%Colore e forma:White Solid PowderPeso molecolare:435.52Aviptadil Acetate
CAS:Aviptadil Acetate (Vasoactive Intestinal Peptide acetate salt) induces pulmonary vasodilation and inhibits the proliferation of vascular SMCs.Formula:C147H238N44O42S·C2H4O2Purezza:>99.99%Colore e forma:SolidPeso molecolare:3385.9(Sar¹)-Angiotensin II acetate
<p>(Sar¹)-Angiotensin II acetate, an analogue of Angiotensin II, is a specific agonist of angiotensin AT1 receptor.</p>Formula:C51H75N13O12Purezza:99.89%Colore e forma:SoildPeso molecolare:1062.22ANGIOTENSIN IV TFA(12676-15-2(free base))
ANGIOTENSIN IV TFA is a less effective agonist at the angiotensin AT1 receptor.Formula:C42H55F3N8O10Purezza:99.12%Colore e forma:SolidPeso molecolare:888.92Novokinin acetate
Novokinin acetate binds AT2 receptor (Ki=7 nM); antihypertensive effect blocked by PD123319.Formula:C41H65N11O9Purezza:99.37%Colore e forma:SoildPeso molecolare:856.02A 779 TFA(159432-28-7 free base)
A 779 TFA is a potent antagonist of angiotensin-(1-7) receptor.Formula:C41H61F3N12O13Purezza:99.55%Colore e forma:SolidPeso molecolare:987.01Alamandine TFA
Alamandine TFA, a RAS peptide, binds MrgD receptors, has anti-hypertensive effects, and protects heart and kidneys.Formula:C42H63F3N12O11Purezza:99.62%Colore e forma:SoildPeso molecolare:969.02Tasosartan
CAS:Tasosartan (WAY-ANA 756) is an antagonist of angiotensin II type 2 (AT2) receptor (IC50 = 1.2 nM).Formula:C23H21N7OPurezza:98.2% - 98.9%Colore e forma:SolidPeso molecolare:411.46BTB06584
CAS:<p>BTB06584: IF1-dependent F1 Fo-ATPase inhibitor; novel AHAS inhibitor targeting MTB.</p>Formula:C19H12ClNO6SPurezza:97.63% - ≥95%Colore e forma:SolidPeso molecolare:417.82Angiotensin I/II (1-5)
CAS:Angiotensin I/II (1-5) is a peptide (ASP-ARG-VAL-TYR-ILE) that contains the amino acids 1-5 and is converted from Angiotensin I/II.Formula:C30H48N8O9Purezza:>99.99%Colore e forma:SolidPeso molecolare:664.75Saralasin acetate(34273-10-4 free base)
CAS:Saralasin acetate is a Non-selective angiotensin II antagonist.Formula:C44H71N13O13Purezza:99.74%Colore e forma:SolidPeso molecolare:990.11PD 123319
CAS:PD 123319 ((S)-(+)-PD 123319) is a potent, selective AT2 angiotensin II receptor antagonist.Formula:C31H32N4O3Purezza:98.61% - 99.65%Colore e forma:SolidPeso molecolare:508.61Olodanrigan sodium
CAS:Olodanrigan sodium (EMA-401 sodium) is an AT2R antagonist, used for neurological disease research.Formula:C32H28NNaO5Purezza:98.14%Colore e forma:SolidPeso molecolare:529.56Olodanrigan
CAS:Olodanrigan (EMA401), a highly selective AT2R antagonist, inhibition of augmented AngII/AT2R induced p38 and p42/p44 MAPK activation.Formula:C32H29NO5Purezza:98.33%Colore e forma:SolidPeso molecolare:507.58Azilsartan Medoxomil
CAS:Azilsartan Medoxomil (TAK-491) is an orally administered angiotensin II receptor type 1 antagonist with IC50 of 0.62 nM, which used in the treatment of adultsFormula:C30H24N4O8Purezza:99.83%Colore e forma:SolidPeso molecolare:568.53VTP-27999 TFA
CAS:VTP-27999 TFA is an inhibitor of Renin (IC50 : 0.47 nM).Formula:C28H42ClF3N4O7Purezza:98.84%Colore e forma:SolidPeso molecolare:639.1SSAA09E2
CAS:SSAA09E2 is a new SARS-CoV replication inhibitor, acting by blocking early interactions of SARS-S with the receptor for SARS-CoV, Angiotensin Converting Enzyme-Formula:C16H20N4O2Purezza:99.41%Colore e forma:SolidPeso molecolare:300.36Acein acetate
<p>ACE ligand with Kd 2.79 nM, inactive on ACE up to 500 nM. Boosts NMDA/D-serine-induced dopamine release in striatum.</p>Formula:C45H72N10O15Purezza:99.43%Colore e forma:SolidPeso molecolare:993.11Azilsartan Methyl Ester
CAS:<p>Azilsartan Methyl Ester, an angiotensin II blocker, inhibits [125I]AII binding to adrenal cortex; IC50: 0.44uM.</p>Formula:C26H22N4O5Purezza:99.87%Colore e forma:SolidPeso molecolare:470.48Methyl candesartan
CAS:Methyl candesartan (Candesartan Methyl Ester) 是一种有效的血管紧张素2受体拮抗剂，可用于研究高血压。Formula:C25H22N6O3Purezza:98.82%Colore e forma:SolidPeso molecolare:454.48Faricimab
CAS:Faricimab,Bispecific antibody targeting Ang-2/VEGF-A. Prevents retinal I/R injury. Improves vision in w-AMD, DME, RVO.Purezza:>95% (SDS-PAGE); >95% (SEC-HPLC) - >95% (SDS-PAGE); >95% (SEC-HPLC)Colore e forma:LiquidLosartan D4
CAS:Losartan D4 (DuP-753 D4) is a deuterated isotope of Losartan for isotopic tracing. Losartan is an angiotensin II receptor antagonist (IC50=20 nM).Formula:C22H23ClN6OPurezza:98%Colore e forma:SolidPeso molecolare:426.94VTP-27999
CAS:VTP-27999 is an alkyl amine Renin inhibitor. VTP-27999 has been used in trials studying the basic science of Renal Function.Formula:C26H41ClN4O5Purezza:98%Colore e forma:SolidPeso molecolare:525.08UR-7247
CAS:UR-7247 is an orally active AT1 receptor antagonist with long-lasting effects, high protein binding, and potential application in cardiovascular pharmacology studies.Formula:C24H26N6O2Purezza:100% - 98.88%Colore e forma:SolidPeso molecolare:430.5CGP48369
CAS:<p>CGP48369 is a potent angiotensin II receptor antagonist with antihypertensive effects that enhances endothelium-dependent relaxation of coronary arteries in</p>Formula:C26H30N6OPurezza:99.27%Colore e forma:SolidPeso molecolare:442.56Pomisartan
CAS:Pomisartan (BIBR-363) is a small molecule angiotensin type 1 receptor (AT1R) antagonist that is used in the treatment of cardiovascular disease, studying heartFormula:C31H30N4O2Purezza:>99.99%Colore e forma:SolidPeso molecolare:490.6L162441
CAS:L162441 is an antagonist of Angiotensin type 1 receptor.Formula:C34H43N5O5SPurezza:98%Colore e forma:SolidPeso molecolare:633.8Pratosartan
CAS:Pratosartan is a selective antagonist of angiotensin II receptor.Formula:C25H26N6OPurezza:98%Colore e forma:SolidPeso molecolare:426.51BMS 183920
CAS:BMS 183920 is a potent Angiotensin II Receptor antagonist that improves improves Caco-2 cell permeability in vivo.Formula:C26H19N5O3Purezza:98.92%Colore e forma:SolidPeso molecolare:449.46Ripisartan
CAS:Ripisartan (UP-269-6) is a potent and specific angiotensin II receptor antagonist that inhibits angiotensin II-mediated sympathetic tachycardia responses.Formula:C23H22N8OPurezza:98.52%Colore e forma:SolidPeso molecolare:426.47Terlakiren
CAS:Terlakiren (CP-80,794) is a renin inhibitor that inhibits the potency of human renin and can be used to study neurological disorders of the hypertensive type.Formula:C31H48N4O7SPurezza:99.38%Colore e forma:SolidPeso molecolare:620.8Buloxibutid
CAS:<p>Buloxibutid: a novel AT2 receptor agonist, Ki=0.4 nM (AT2), 10 μM (AT1).</p>Formula:C23H29N3O4S2Purezza:97.68% - 98.58%Colore e forma:SolidPeso molecolare:475.62ZD-6888 Hydrochloride
CAS:ZD-6888 Hydrochloride, an angiotensin type 1 receptor antagonist, is used potentially for the treatment of hypertension.Formula:C25H26ClN5OPurezza:98.61% - 99.60%Colore e forma:SolidPeso molecolare:447.96L-162,313
CAS:L-162,313 is an ANG II receptor agonist, a nonpeptide that mimics the biological actions of angiotensin II and induces an increase in MAP.Formula:C30H38N4O4S2Purezza:98.21%Colore e forma:SolidPeso molecolare:582.78CL-329167
CAS:CL-329167 (compound 12) is an orally active, competitive angiotensin II receptor antagonist (IC50=6 nM) suitable for hypertension research.Formula:C30H32N6O2Purezza:99.42%Colore e forma:SolidPeso molecolare:508.61KR31173
CAS:KR31173 is an AT1 antagonist with an IC50 of 3.27 nM. When labeled with the 11C isotope, KR31173 can be used as a tracer for positron emission tomography (PET). In mice, KR31173 exhibits favorable biodistribution and pharmacological characteristics. It selectively binds to organs in CD-1 mice known to have a high density of AT1 angiotensin receptors.Formula:C31H30N8O2Colore e forma:SolidPeso molecolare:546.62ACT 178882
CAS:ACT 178882 is a new Renin inhibitor (IC50: 1.4 nM).Formula:C33H38Cl3N3O4Purezza:98%Colore e forma:SolidPeso molecolare:647.03L162389
CAS:L162389 is an angiotensin II receptor antagonist with a balanced affinity for AT1 and AT2 receptor and stimulates the conversion of phosphatidylinositol.Formula:C31H38N4O4SPurezza:99.11% - 99.57%Colore e forma:SolidPeso molecolare:562.72ZD 7155 hydrochloride
CAS:ZD 7155 hydrochloride is an angiotensin II receptor type 1 (AT1 receptor) antagonist.Formula:C26H27ClN6OPurezza:99.8%Colore e forma:SolidPeso molecolare:474.98
