RAAS
Gli inibitori del sistema renina-angiotensina-aldosterone (RAAS) sono composti che prendono di mira la via del RAAS, nota principalmente per il suo ruolo nella regolazione della pressione sanguigna e dell'equilibrio dei fluidi, ma che influenza anche l'angiogenesi. La via del RAAS può contribuire allo sviluppo di nuovi vasi sanguigni nei tumori, supportandone così la crescita. Inibire i componenti del RAAS può quindi avere effetti anti-angiogenici, rendendo questi inibitori preziosi nel trattamento di alcuni tumori e disturbi vascolari. Presso CymitQuimica, offriamo una gamma di inibitori di alta qualità del RAAS per supportare la tua ricerca in biologia cardiovascolare, oncologia e angiogenesi.
Trovati 95 prodotti per "RAAS".
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Aclerastide
CAS:Aclerastide, an angiotensin receptor agonist, decreases fibrosis in wounds; effect increases with use duration, blocked by AT antagonist.Formula:C42H64N12O11Colore e forma:SolidPeso molecolare:913.03TRV056
CAS:TRV056 is a Gq-biased AT1R agonist effective in Gq-mediated signaling and a basis for similar drug development.Formula:C52H74N14O13Colore e forma:SolidPeso molecolare:1103.249Angiotensin II (1-4), human TFA
Angiotensin II is a potent direct vasoconstrictor, causing arteries and veins to constrict, so leading to an increase in blood pressure.Formula:C26H38F3N7O10Purezza:98%Colore e forma:SolidPeso molecolare:665.62Handle region peptide, rat
CAS:Rat handle region peptide acts as prorenin receptor blocker, curbs diabetic kidney disease, and reduces eye inflammation.Formula:C54H101N15O12SPurezza:98%Colore e forma:SolidPeso molecolare:1184.54Azilsartan Medoxomil Potassium
CAS:Azilsartan Medoxomil Potassium (TAK-491 Potassium) is an orally administered angiotensin II receptor type 1 antagonist with IC50 of 0.62 nM, which used in the treatment of adults with essential hypertension.Formula:C30H23N4O8·KPurezza:99.99%Colore e forma:SolidPeso molecolare:606.62Brain Natriuretic Peptide (1-32), rat
CAS:Rat Brain Natriuretic Peptide (1-32) is a 32-amino-acid peptide from heart, released when ventricles stretch excessively.Formula:C146H239N47O44S3Purezza:98%Colore e forma:SolidPeso molecolare:3452.94PRO20
PRO20 is a specific and competitive antagonist of the (pro)renin receptor (PRR). It inhibits the calcium influx induced by Proproin with an IC50 value of 81 nmol/L. By blocking the binding of Prorenin to PRR, PRO20 inhibits the activation of the renin-angiotensin system (RAS), reducing the production of angiotensin II (Ang II) and exerting antihypertensive effects. PRO20 holds promise for research in antihypertensive agents.Colore e forma:Odour SolidRenin FRET Substrate I
CAS:Renin FRET Substrate I, designed for human renin, contains angiotensinogen's N-terminal cleavage site.Formula:C90H120N22O16SColore e forma:SolidPeso molecolare:1798.15Evazarsen sodium
CAS:Evazarsen sodium, an angiotensinogen synthesis inhibitor, possesses antihypertensive properties [1].Formula:C296H414N86O146P20S19Na20Colore e forma:SolidPeso molecolare:9201.6A 779
CAS:A 779 is a potent antagonist of the G-protein-coupled receptor Mas, the Ang1-7 receptor, which is distinct from conventional AngII.Formula:C39H60N12O11Purezza:98%Colore e forma:SolidPeso molecolare:872.97CGP-42112 acetate
CGP-42112 acetate is a potent angiotensin receptor AT2 agonist that inhibits the increase in protein kinase A activity produced by LPS.Formula:C54H73N13O13Purezza:99.92% - 99.94%Colore e forma:SolidPeso molecolare:1112.24Ref: TM-T14939L
1mg55,00€5mg167,00€10mg241,00€25mg374,00€1mL*10mM (DMSO)374,00€50mg504,00€100mg665,00€TRV120055
CAS:TRV120055 is a Gq-biased agonist with 10x more efficacy on AT1R-Gq than AT1R-βarr2.Formula:C34H54N12O7Peso molecolare:742.883Angiotensin II (5-8), human
CAS:Angiotensin II (5-8) is an endogenous C-terminal fragment of the peptide vasoconstrictor angiotensin IIFormula:C26H36N6O5Purezza:98%Colore e forma:SolidPeso molecolare:512.6Angiotensin II (1-4), human
CAS:Angiotensin II constricts blood vessels and boosts blood pressure by escalating norepinephrine release.Formula:C24H37N7O8Purezza:98%Colore e forma:SolidPeso molecolare:551.59Alunacedase alfa
CAS:Alunacedase alfa (APN-01) is an angiotensin-converting enzyme 2 with antiviral activity.Purezza:99.1% (SDS-PAGE); 99.9% (SEC-HPLC) - 99.1% (SDS-PAGE); 99.9% (SEC-HPLC)Colore e forma:LiquidPeso molecolare:85.03 kDaAngiogenin (108-122)
CAS:Angiogenin (108-122) peptide treats cancer, infectious, fibrotic, inflammatory, neurodegenerative, autoimmune, and heart diseases.Formula:C78H125N25O23Colore e forma:SolidPeso molecolare:1780.98Losartan (D4 Carboxylic Acid)
CAS:Losartan D4 Carboxylic Acid is the deuterium labeled Losartan, which is an angiotensin II receptor antagonist.Formula:C22H21ClN6O2Purezza:98%Colore e forma:SolidPeso molecolare:440.919Olmesartan-D4
CAS:Olmesartan D4 is the deuterium labeled Olmesartan. Olmesartan is an antagonist of angiotensin II receptor (AT1R) used to treat high blood pressure.Formula:C24H26N6O3Purezza:98%Colore e forma:SolidPeso molecolare:450.526Angiotensin II 5-valine
CAS:ngiotensin II 5-valine is an angiotensin II analog which is an agonist at angiotensin receptors.Formula:C49H69N13O12Purezza:98%Colore e forma:SolidPeso molecolare:N/ASpirapril hydrochloride
CAS:Spirapril hydrochloride (SCH 33844 hydrochloride) is a potent angiotensin converting enzyme inhibitor with antihypertensive activity that competitively blocks the conversion of angiotensin I to angiotensin II, functions as an orally active proagent of spiraprilat, and is extensively utilized in cardiovascular research focused on hypertension and congestive heart failure pathophysiology and therapeutic intervention.Formula:C22H31ClN2O5S2Purezza:99.78%Colore e forma:White SolidPeso molecolare:503.07
