Riduttasi
Le reduttasi sono una vasta classe di enzimi che catalizzano la riduzione delle molecole in vari percorsi biochimici. In endocrinologia, specifiche reduttasi, come la 5α-reduttasi, sono cruciali per il metabolismo degli ormoni steroidei, inclusa la conversione del testosterone in diidrotestosterone (DHT). Gli inibitori degli enzimi reduttasi sono utilizzati nel trattamento di condizioni come l'iperplasia prostatica benigna e l'alopecia androgenetica. Presso CymitQuimica, offriamo una varietà di inibitori delle reduttasi di alta qualità per supportare la tua ricerca nella regolazione ormonale, nelle vie metaboliche e nello sviluppo terapeutico.
Trovati 56 prodotti per "Riduttasi".
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Zenarestat
CAS:Zenarestat is an orally active aldose reductase inhibitor capable of ameliorating diabetic peripheral neuropathy in rats with type 2 diabetes.Formula:C17H11BrClFN2O4Purezza:99.51% - 99.51%Colore e forma:White SolidPeso molecolare:441.64AY 9944
CAS:AY 9944 inhibits DHCR7 enzyme (IC50=13 nM) and sterol isomerase, leading to hypocholesterolemia and 7DHC buildup.Formula:C22H30Cl4N2Purezza:98.92% - 99.65%Colore e forma:White SolidPeso molecolare:464.3AKR1C3-IN-14
CAS:AKR1C3-IN-14 (compound 4) is an inhibitor of AKR1C3 enzyme, exhibiting an IC50 value of 0.122 μM. It reduces excess androgen production by inhibiting the activity of the AKR1C3 enzyme, thereby regulating hormone-mediated signaling. Additionally, AKR1C3-IN-14 plays a role in the biosynthesis of prostaglandin PGF2α, influencing this pathway to regulate cell proliferation. This compound is utilized in the research of prostate cancer.Formula:C21H21BrN2O4Peso molecolare:445.31Risarestat
CAS:Risarestat (CT-112) is a potent aldose reductase inhibitor and thyroid hormone receptor (TR) antagonist for the treatment of hypoglycemia.Formula:C16H21NO4SPurezza:98.39%Colore e forma:SolidPeso molecolare:323.41SN34037
CAS:SN34037, specific Aldo-keto reductase 1C3 (AKR1C3) inhibitor, inhibiting the cytotoxic activity of PR-104A, suitable for studying PR-104A-responsive leukaemia.Formula:C15H19Cl2N3O2Purezza:99.03%Colore e forma:Yellow SolidPeso molecolare:344.24Fidarestat
CAS:Fidarestat (SNK 860),Aldose reductase inhibitor (IC50=26 nM). Targets AKR1B10 (33 μM) and V301L AKR1B10 (1.8 μM). Potential diabetes treatment.Formula:C12H10FN3O4Purezza:98%Colore e forma:White SolidPeso molecolare:279.22Izonsteride
CAS:Izonsteride (LY320236) is a selective and potent 5alpha reductase inhibitor with dual action on the type I and type II isoforms of the enzyme.Izonsteride isFormula:C24H26N2OS2Purezza:99.5%Colore e forma:SolidPeso molecolare:422.61Caracemide
CAS:Caracemide (NSC-253272) inhibits the enzyme ribonucleotide reductase of Escherichia coli. Caracemide can be used in anticancer studies.Formula:C6H11N3O4Purezza:99.8%Colore e forma:SolidPeso molecolare:189.17Minalrestat
CAS:Minalrestat(ARI-509) is an orally active and potent aldose reductase inhibitor for the study of impaired microvascular reactivity in diabetic patients.Formula:C19H11BrF2N2O4Purezza:98.64% - 99.88%Colore e forma:SolidPeso molecolare:449.2Lidorestat
CAS:Lidorestat (IDD-676) is an aldose reductase inhibitor (IC50: 5 nM) with effective, selective and oral activity.Formula:C18H11F3N2O2SPurezza:99.98%Colore e forma:SolidPeso molecolare:376.35Zopolrestat
CAS:Zopolrestat (CP 73850) is a potent inhibitor of aldose reductase (IC50 = 3.1 nM).Formula:C19H12F3N3O3SPurezza:99.74% - 99.82%Colore e forma:SolidPeso molecolare:419.38Ranirestat
CAS:Ranirestat (AS-3201) is an AR inhibitor with neuroprotective properties that improves peripheral nerve dysfunction in rats with advanced diabetic polyneuropathyFormula:C17H11BrFN3O4Purezza:96.10% - 99.44%Colore e forma:SolidPeso molecolare:420.19NSC 645827
CAS:NSC 645827 is an inhibitor of NAD(P)H:quinone oxidoreductase 1 (NQO1), with an IC50 of 0.7 μM.Formula:C17H17N5O2Colore e forma:SolidPeso molecolare:323.349RJG-2051
CAS:RJG-2051 is a selective covalent inhibitor of aldo-keto reductase family 1 member C3 (AKR1C3), with an IC50 value of 13 nM. It interferes with the metabolism of substrates such as androgens, estrogens, and prostaglandins through AKR1C3. RJG-2051 holds potential for cancer research.Formula:C26H31N5O4SColore e forma:SolidPeso molecolare:509.62(Rac)-Fidarestat
CAS:(Rac)-Fidarestat ((Rac)-SNK 860) is the racemic form of Fidarestat, functioning as a potent inhibitor of the enzyme aldose reductase.Formula:C12H10FN3O4Colore e forma:SolidPeso molecolare:279.224ALR2-IN-7
CAS:ALR2-IN-7 (Compound 5a) is a potent and selective inhibitor of alditol reductase (ALR2/AKR1B1) with a Ki of 8.71 nM. It holds potential for research into diabetic complications such as retinopathy and nephropathy, as well as cancer.Formula:C17H15NO3Colore e forma:SolidPeso molecolare:281.31
