Recettore dei glucocorticoidi
Il recettore dei glucocorticoidi (GR) è un recettore ormonale nucleare che media gli effetti dei glucocorticoidi, una classe di ormoni steroidei coinvolti nella regolazione del metabolismo, della risposta immunitaria e dello stress. Gli agonisti e antagonisti del recettore dei glucocorticoidi sono ampiamente utilizzati nel trattamento delle malattie infiammatorie e autoimmuni, così come nella terapia del cancro. I modulatori del GR sono anche strumenti importanti per studiare i ruoli fisiologici e patologici dei glucocorticoidi. Presso CymitQuimica, offriamo una vasta gamma di modulatori del recettore dei glucocorticoidi di alta qualità per supportare la tua ricerca in endocrinologia, immunologia e regolazione ormonale.
Trovati 166 prodotti di "Recettore dei glucocorticoidi"
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Dexamethasone palmitate
CAS:DXP, a lipophilic prodrug of Dexamethasone, has 47x less glucocorticoid receptor affinity; it's an agonist & anti-inflammatory.Formula:C38H59FO6Purezza:99.28%Colore e forma:SolidPeso molecolare:630.87Spirorenone
CAS:Spirorenone (INN) is a novel aldosterone antagonist with anti-salt corticosteroid activity, used in metabolic disease research.Formula:C24H28O3Purezza:98.28% - 99.84%Colore e forma:SolidPeso molecolare:364.48Halobetasol
CAS:Halobetasol (Ulobetasol), a corticosteroid, is utilized in the research of severe localized psoriasis [1].Formula:C22H27ClF2O4Purezza:98%Colore e forma:SolidPeso molecolare:428.9Dagrocorat
CAS:Dagrocorat is a novel and dissociated agonist of glucocorticoid receptor.Formula:C29H29F3N2O2Purezza:98%Colore e forma:SolidPeso molecolare:494.55Glucocorticoid receptor agonist
CAS:Glucocorticoid receptor agonist is an effective glucocorticoid receptor agonist.Formula:C20H20F4N2O2Purezza:98%Colore e forma:SolidPeso molecolare:396.38Fosdagrocorat
CAS:Fosdagrocorat is an agonist of the dissociated glucocorticoid receptor.Formula:C29H30F3N2O5PColore e forma:SolidPeso molecolare:574.5311β-hydroxy Etiocholanolone
CAS:11β-Hydroxyetiocholanolone, a hydrocortisone metabolite, exhibits elevated fecal levels in giraffes (G. camelopardalis) and plains zebras (E. quagga) in response to environmental stress.Formula:C19H30O3Colore e forma:SolidPeso molecolare:306.44RU28362
CAS:RU28362 is an agonist of glucocorticoid receptor.Formula:C23H28O3Colore e forma:SolidPeso molecolare:352.4720α-dihydro Prednisolone
CAS:"20α-Dihydro Prednisolone, a prednisolone metabolite, is detected in cattle urine post-adrenocorticotropic hormone (ACTH) administration but absent in both naturally stressed and non-stressed cattle."Formula:C21H30O5Colore e forma:SolidPeso molecolare:362.466Amebucort
CAS:Amebucort is a synthetic glucocorticoid corticosteroid. It may used for the research of inflammatory disorders.Formula:C28H40O7Purezza:98%Colore e forma:SolidPeso molecolare:488.61HP210
CAS:HP210, a selective glucocorticoid receptor modulator (SGRM), can suppress IL-1β and IL-6 mRNA expression, suggesting its utility in investigating inflammation-Formula:C22H19N3O2S2Purezza:98%Colore e forma:SolidPeso molecolare:421.54Baxdrostat
CAS:<p>Baxdrostat is an aldosterone synthase inhibitor.</p>Formula:C22H25N3O2Purezza:99.8%Colore e forma:SolidPeso molecolare:363.45ORIC-101
CAS:ORIC-101 is a highly effective and selective glucocorticoid receptor antagonist (EC50: 5.6 nM). It also has anti-cancer activity.Formula:C34H47NO2Purezza:98%Colore e forma:SolidPeso molecolare:501.74LEO 134310
CAS:LEO 134310: Selective, non-steroidal GR agonist with 14 nM EC50, for topical skin disease treatment.Formula:C34H40N2O8Colore e forma:SolidPeso molecolare:604.69GSK866
CAS:GSK866 is a selective glucocorticoid receptor agonist (SEGRA).Formula:C23H21Cl2F4N5O3Colore e forma:SolidPeso molecolare:562.34Dazucorilant
CAS:Dazucorilant (CORT113176), a selective non-steroidal GR modulator, has high affinity with a K i <1 nM, useful for neurological research.Formula:C29H22F4N4O3SColore e forma:SolidPeso molecolare:582.57C108297
CAS:C108297: glucocorticoid modulator, combats diet obesity/inflammation, reduces appetite/lipid storage, boosts fat burn.Formula:C30H36FN3O4SPurezza:98%Colore e forma:SolidPeso molecolare:553.69Glucocorticoid receptor activator 1
CAS:Glucocorticoid Receptor Activator 1, a phenyl nitrogen-heterocyclic precursor, acts as an activator of the glucocorticoid receptor (GR). By activating GR, it downregulates the expression of pro-inflammatory genes stimulated by TNF, making it useful for inflammation research.Formula:C11H15Cl2NO2Colore e forma:SolidPeso molecolare:264.15JTP-117968
CAS:JTP-117968: Non-steroidal SGRM, glucocorticoid receptor modulator, IC50 = 6.8 nM, offers better inhibitory/activatory balance.Formula:C31H31F3N2O2Colore e forma:SolidPeso molecolare:520.59S-HP210
S-HP210: selective GR modulator, blocks NF-κB (IC50: 1.92 μM), non-toxic to mouse fibroblasts.Formula:C22H19N3O2S2Colore e forma:SolidPeso molecolare:421.54
