Recettore degli androgeni
Il recettore degli androgeni (AR) è un recettore ormonale nucleare che viene attivato dal legame con gli androgeni, come il testosterone e il diidrotestosterone. Questo recettore svolge un ruolo cruciale nello sviluppo e nel mantenimento delle caratteristiche maschili, nonché nella regolazione di diversi processi fisiologici, tra cui la crescita muscolare, la libido e la densità ossea. Gli inibitori del recettore degli androgeni sono ampiamente studiati nel contesto del cancro alla prostata, dove la segnalazione dell'AR è spesso sovraregolata. Presso CymitQuimica, offriamo una gamma di modulatori del recettore degli androgeni di alta qualità per supportare la tua ricerca in endocrinologia, biologia del cancro e regolazione ormonale.
Trovati 229 prodotti di "Recettore degli androgeni"
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Darolutamide
CAS:Darolutamide (BAY-1841788) is an androgen receptor (AR) antagonist that blocks AR nuclear translocation (Ki: 11 nM).Formula:C19H19ClN6O2Purezza:97.36% - >99.99%Colore e forma:SolidPeso molecolare:398.85Ref: TM-T6915
1mg50,00€2mg66,00€5mg100,00€10mg158,00€25mg250,00€50mg358,00€100mg512,00€200mg732,00€1mL*10mM (DMSO)101,00€Dimethylcurcumin
CAS:Dimethylcurcumin (ASC-J9) (ASC-J9) is an androgen receptor degradation enhancer.Formula:C23H24O6Purezza:97.36% - 98.96%Colore e forma:SolidPeso molecolare:396.43Testosterone acetate
CAS:Testosterone acetate (NSC-523836) is a hormone with in vitro antitumor activity.Formula:C21H30O3Purezza:99.6%Colore e forma:White To Off-White Crystalline PowderPeso molecolare:330.46GSK-2881078
CAS:GSK-2881078 is a selective androgen receptor modulato (SARM) that is being evaluated for effects on muscle growth and strength in subjects with muscle wasting.Formula:C14H13F3N2O2SPurezza:98.16% - 98.81%Colore e forma:SolidPeso molecolare:330.33MI-136
CAS:MI-136 inhibits expression of androgen receptor (AR) target genes that DHT induced.Formula:C23H21F3N6SPurezza:98.63% - 99.12%Colore e forma:SolidPeso molecolare:470.51Ref: TM-T6889
1mg47,00€5mg87,00€10mg147,00€25mg279,00€50mg472,00€100mg730,00€200mg1.017,00€1mL*10mM (DMSO)97,00€Nandrolone phenylpropionate
CAS:Nandrolone phenylpropionate (Nandrolone phenpropionate) is an androgen receptor agonist. It mainly used to treat women with breast cancer and osteoporosisFormula:C27H34O3Purezza:99.2% - 99.46%Colore e forma:White Or Milky Crystalline PowderPeso molecolare:406.56YK11
CAS:YK11 is an androgen receptor partial agonist that activates androgen receptor transcriptional activity in HEK293 cells overexpressing androgen receptors when used at a concentration of 0.1 μM, with osteogenic activity.Formula:C25H34O6Purezza:98.91%Colore e forma:SoildPeso molecolare:430.533-(7,7-dimethyl-5-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-2-yl)-1H-indole-7-carbonitrile
CAS:3-[7 ,7- dimethyl-5-oxo -6H-pyrrolo[3,4-b]pyridin-2-yI]-1H-indole-7 -carbonitrile is an androgen receptor modulator.Formula:C18H14N4OPurezza:98.41%Colore e forma:SolidPeso molecolare:302.332-hydroxy Flutamide
CAS:2-hydroxy Flutamide is competitive inhibition of androgen receptor (AR) for the treatment of prostate cancerFormula:C11H11F3N2O4Purezza:99.45% - 99.82%Colore e forma:SolidPeso molecolare:292.21Testosterone undecanoate
CAS:Testosterone undecanoate is a metabolite of Testosterone, which is a promising androgen for male hormonal contraception.Formula:C30H48O3Purezza:99.45% - 99.788%Colore e forma:White Crystalline PowderPeso molecolare:456.7Apalutamide
CAS:Apalutamide (ARN-509) is a small molecule and androgen receptor (AR) antagonist with potential antineoplastic activity.
Formula:C21H15F4N5O2SPurezza:99.03% - 99.91%Colore e forma:SolidPeso molecolare:477.43AH-3960
CAS:AH-3960 是一种甲状腺激素受体 1 (PTHR1) 激动剂。Formula:C13H22N4O3Purezza:98.44%Colore e forma:SolidPeso molecolare:282.34VPC-13163
CAS:VPC-13566 inhibits growth in LNCaP, Enzalutamide-resistant MR49F, lowers AR gene, PSA, TMPRSS2 expression, but not in AR-independent PC3 cells.Formula:C16H14N2Purezza:98.02%Colore e forma:SolidPeso molecolare:234.3Ref: TM-T29110
1mg85,00€2mg111,00€5mg177,00€10mg269,00€25mg429,00€50mg610,00€100mg820,00€200mg1.071,00€1mL*10mM (DMSO)165,00€S-23
CAS:S-23 ((S)-3-(4-chloro-3-fluorophenoxy)-N-(4-cyano-3-(trifluoromethyl)phenyl)-2-hydroxy-2-methylpropanamide) is an oral selective androgen receptor modulator (Formula:C18H13ClF4N2O3Purezza:99.55%Colore e forma:SolidPeso molecolare:416.75Iprodione
CAS:Iprodione is a fungicide. Iprodione is also used in cannabis testing kits as a component of pesticide mixes.Formula:C13H13Cl2N3O3Purezza:98.82%Colore e forma:Colorless Crystals Cream To Colorless Odorless PowderPeso molecolare:330.17Bavdegalutamide
CAS:Bavdegalutamide (ARV-110) is a PROTAC degrader of androgen receptor (AR).Formula:C41H43ClFN9O6Purezza:97.17% - 99.04%Colore e forma:SolidPeso molecolare:812.29N-desmethyl Enzalutamide
CAS:N-desmethyl Enzalutamide (N-desmethyl MDV 3100) is the active Enzalutamide metabolite.It is the active metabolite of Enzalutamide.Formula:C20H14F4N4O2SPurezza:99.74%Colore e forma:SolidPeso molecolare:450.41Ref: TM-T19450
2mg33,00€5mg50,00€10mg71,00€25mg131,00€50mg243,00€100mg355,00€200mg504,00€1mL*10mM (DMSO)55,00€Enzalutamide carboxylic acid
CAS:Enzalutamide carboxylic acid is an antagonist of androgen receptor (AR) .
Formula:C20H13F4N3O3SPurezza:97.88%Colore e forma:SolidPeso molecolare:451.39Lupeol
CAS:Lupeol (Monogynol B) is a novel androgen receptor inhibitor with anti-inflammatory and antioxidant activity.Formula:C30H50OPurezza:98% - 99.96%Colore e forma:Needles From Alcohol Acetone White PowderPeso molecolare:426.72VPC-13566
CAS:VPC-13566 is a BF3-specific small molecule, which effectively inhibited the androgen receptor transcriptional activity and displaced the BAG1L peptide from the
Formula:C18H14N2Purezza:99.55%Colore e forma:SolidPeso molecolare:258.32Galeterone
CAS:Galeterone (VN 124) is an oral androgen receptor modulator/CYP17 inhibitor with antiandrogen properties, targeting prostate cancer growth.Formula:C26H32N2OPurezza:99.47% - 99.773%Colore e forma:SolidPeso molecolare:388.55CLP-3094
CAS:CLP-3094 (2-([2-(4-CHLOROPHENOXY)ETHYL]THIO)-1H-BE) is a potent androgen receptor BF3 (binding function 3) inhibitor.Formula:C15H13ClN2OSPurezza:99.84%Colore e forma:SolidPeso molecolare:304.79Ref: TM-T9179
1mg52,00€5mg114,00€10mg188,00€25mg331,00€50mg495,00€100mg705,00€500mg1.415,00€1mL*10mM (DMSO)125,00€JNJ-63576253 free base
CAS:JNJ-63576253 free base (TRC253) is a potent and orally active full antagonist of androgen receptor (AR). JNJ-63576253 can be used for the research of CRPC.Formula:C23H21F3N6O2SPurezza:98.32%Colore e forma:SolidPeso molecolare:502.51Ref: TM-T8933
2mg40,00€5mg52,00€10mg89,00€25mg167,00€50mg258,00€100mg379,00€200mg540,00€1mL*10mM (DMSO)90,00€CTK8A3536
CAS:CTK8A3536 ((2-MORPHOLIN-4-YL-4-PHENYL-1,3-THIAZOL-5-YL)METHANOL) is an inhibitor of Androgen receptor.Formula:C14H16N2O2SPurezza:99.62%Colore e forma:SolidPeso molecolare:276.35Ref: TM-T8592
1mg88,00€5mg170,00€10mg259,00€25mg425,00€50mg598,00€100mg810,00€200mg1.074,00€1mL*10mM (DMSO)169,00€Ailanthone
CAS:Ailanthone (Δ13-Dehydrochaparrinone) is an effective inhibitor of both full-length androgen receptor (AR) (IC50: 69 nM) and constitutively active truncated ARFormula:C20H24O7Purezza:99.71% - 99.96%Colore e forma:SolidPeso molecolare:376.4Ref: TM-TQ0209
1mg40,00€5mg84,00€10mg110,00€25mgPrezzo su richiesta50mgPrezzo su richiesta1mL*10mM (DMSO)93,00€ARD-2128
CAS:ARD-2128: potent oral PROTAC that degrades AR, curbing prostate cancer growth with no toxicity.Formula:C45H50ClN7O6Purezza:98.8%Colore e forma:SolidPeso molecolare:820.37Boldenone Undecylenate
CAS:Boldenone Undecylenate (Parenabol) is a synthetic steroid.Formula:C30H44O3Purezza:99.39%Colore e forma:Light Yellow Oily MatterPeso molecolare:452.67Ref: TM-T3137
1mg35,00€2mg48,00€5mg52,00€10mg85,00€25mg140,00€50mg246,00€100mg396,00€500mg939,00€1mL*10mM (DMSO)52,00€Triptophenolide
CAS:Triptophenolide (Hypolide) is a compound isolated from Tripterygium wilfordii Hook with anti-inflammatory activity.Formula:C20H24O3Purezza:98.07% - ≥95%Colore e forma:White PowderPeso molecolare:312.40AC-262536
CAS:AC-262536 is a selective androgen receptor (SAR) modulator and exhibits potent agonist activity at the androgen receptor.Formula:C18H18N2OPurezza:99.88%Colore e forma:SolidPeso molecolare:278.35Ref: TM-T26539
5mg46,00€10mg74,00€25mg145,00€50mg240,00€100mg359,00€200mg510,00€1mL*10mM (DMSO)49,00€Enzalutamide
CAS:Enzalutamide (MDV3100) is an androgen receptor (AR) antagonist (IC50=36 nM in LNCaP).Formula:C21H16F4N4O2SPurezza:99% - 99.93%Colore e forma:SolidPeso molecolare:464.44Ref: TM-T6002
5mg48,00€10mg56,00€25mg74,00€50mg96,00€100mg154,00€200mg187,00€500mg274,00€1mL*10mM (DMSO)52,00€RU 58841
CAS:RU 58841 (PSK-3841) is a specific androgen receptor antagonist or anti-androgen; RU 58841(PSK-3841) has a significant effect on hair regrowth.Formula:C17H18F3N3O3Purezza:99.31% - 99.70%Colore e forma:SolidPeso molecolare:369.34Ref: TM-T2236
5mg40,00€10mg63,00€25mg99,00€50mg130,00€100mg177,00€200mg245,00€500mg371,00€1mL*10mM (DMSO)48,00€EPI-001
CAS:EPI-001 is an androgen receptor N-terminal domain antagonist with IC50 of ～6 μM and a selective PPAR-gamma modulator.Formula:C21H27ClO5Purezza:99% - 99.67%Colore e forma:SolidPeso molecolare:394.89Ref: TM-T6829
2mg35,00€5mg50,00€10mg77,00€25mg127,00€50mg202,00€100mg303,00€200mg449,00€1mL*10mM (DMSO)51,00€Clascoterone
CAS:Clascoterone (CB-03-01) is a new topical and peripherally selective androgen antagonist.
Formula:C24H34O5Purezza:99.2% - 99.64%Colore e forma:SolidPeso molecolare:402.52DSRM-3716
CAS:Isoquinoline, 5-iodo- (9CI) is a potent and selective inhibitor of SARM1(IC50 = 75 nM) by preventing axonal degeneration and by allowing functional recovery ofFormula:C9H6INPurezza:97.28% - 99.785%Colore e forma:SolidPeso molecolare:255.06p,p'-DDE
CAS:p,p'-DDE (p,p'-dichlorodiphenyldichloroethylene) is a metabolite and degradation product of the organochlorine pesticide DDTFormula:C14H8Cl4Purezza:99.68%Colore e forma:White Crystalline Solid Physical Description White Crystalline Solid Or White Powder (Ntp 1992)Peso molecolare:318.03CSRM617 hydrochloride
CAS:CSRM617 hydrochloride: selective OC2 inhibitor, Kd 7.43 uM, binds OC2-HOX, induces apoptosis, tolerable in mouse prostate cancer.Formula:C10H14ClN3O5Purezza:99.59%Colore e forma:SoildPeso molecolare:291.69LY2452473
CAS:LY2452473 (OPK 88004) is an orally available and selective androgen receptor modulator with potential anticancer activity for the study of prostate cancer.Formula:C22H22N4O2Purezza:99.72%Colore e forma:SolidPeso molecolare:374.44Ref: TM-T15804
1mg34,00€5mg67,00€10mg96,00€25mg133,00€50mg170,00€100mg253,00€200mg386,00€1mL*10mM (DMSO)73,00€Masofaniten
CAS:Masofaniten (EPI-7386) is an orally active androgen receptor (AR) inhibitor with antitumor activity for the study of prostate and breast cancer.Formula:C24H24Cl2N4O4SPurezza:98.42% - 98.66%Colore e forma:SolidPeso molecolare:535.44Estromustine
CAS:Estromustine, an active metabolite of estramustine phosphate, is used to treat prostate cancer.Formula:C23H29Cl2NO3Colore e forma:SolidPeso molecolare:438.39GDC-2992
CAS:GDC-2992 is a selective androgen receptor (AR) degradator that degrades AR and inhibits proliferation in VCaP cells,CRPC.Formula:C45H51ClN8O5Purezza:99.82%Colore e forma:SoildPeso molecolare:819.39AR antagonist 6
CAS:AR antagonist 6 (compound 6i), a diphenyl ether androgen receptor (AR) antagonist, binds to the AR with an affinity of 120 nM. It demonstrates low toxicity and effective in vitro activity in the golden Syrian hamster ear model. [19] [1]
Formula:C16H12F3NO2Colore e forma:SolidPeso molecolare:307.27Procymidone
CAS:Procymidone is a broad-spectrum fungicide that inhibits fungal glycerol triester synthesis, thereby disrupting hyphal growth. androgen receptor (AR) antagonistFormula:C13H11Cl2NO2Purezza:99.86%Colore e forma:Colorless SolidPeso molecolare:284.14JNJ-37654032
CAS:JNJ-37654032: orally active, nonsteroidal SARM. Mixed AR agonist/antagonist. Selective for muscle, grows levator ani, max at 3mg/kg, ED(50) 0.8mg/kg.Formula:C11H7Cl2F3N2OColore e forma:SolidPeso molecolare:311.09Androgen receptor antagonist 4
CAS:Compound AT2 is an AR inhibitor with anticancer effects, blocking DHT action and AR nuclear translocation (IC50=0.15μM).Formula:C22H18ClNColore e forma:SolidPeso molecolare:331.84Chlormadinone (free base)
CAS:Chlormadinone: synthetic hormone, treats BPH and PCOS, blocks androgen/estrogen, boosts bone cell growth.Formula:C21H27ClO3Colore e forma:SolidPeso molecolare:362.89Bifluranol
CAS:Bifluranol (BX341) has anti-androgenic activity and has shown significant anti-prostatic activity in in vivo studies for the treatment of benign prostaticFormula:C17H18F2O2Purezza:99.86%Colore e forma:SolidPeso molecolare:292.32Gumelutamide
CAS:Gumelutamide, a tetrahydropyridopyrimidine compound, functions as both an antiandrogen and an antineoplastic agent by acting as an androgen antagonist.Formula:C22H21ClN6OColore e forma:SolidPeso molecolare:420.89AZD3514
CAS:AZD3514 is a potent and oral androgen receptor downregulator with Ki of 2.2 μM and has ability of reducing AR protein expression.Phase 1.
Formula:C25H32F3N7O2Purezza:98.09%Colore e forma:SolidPeso molecolare:519.56Honokiol DCA
CAS:Honokiol DCA inhibits DRP1, enhances respiration via mitochondrial repair, and is active against Vemurafenib-resistant melanoma.Formula:C22H18Cl4O4Colore e forma:SolidPeso molecolare:488.19Prochloraz
CAS:Prochloraz: broad-spectrum imidazole fungicide; blocks placental aromatase (IC50=40nM), estrogen/androgen receptors; activates aryl hydrocarbon receptors.Formula:C15H16Cl3N3O2Purezza:99.75% - 99.79%Colore e forma:Colorless SolidPeso molecolare:376.67
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