Recettore degli androgeni
Il recettore degli androgeni (AR) è un recettore ormonale nucleare che viene attivato dal legame con gli androgeni, come il testosterone e il diidrotestosterone. Questo recettore svolge un ruolo cruciale nello sviluppo e nel mantenimento delle caratteristiche maschili, nonché nella regolazione di diversi processi fisiologici, tra cui la crescita muscolare, la libido e la densità ossea. Gli inibitori del recettore degli androgeni sono ampiamente studiati nel contesto del cancro alla prostata, dove la segnalazione dell'AR è spesso sovraregolata. Presso CymitQuimica, offriamo una gamma di modulatori del recettore degli androgeni di alta qualità per supportare la tua ricerca in endocrinologia, biologia del cancro e regolazione ormonale.
Trovati 229 prodotti di "Recettore degli androgeni"
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LG-121071
CAS:LG-121071: oral SARM, high-affinity AR full agonist, Ki=17 nM.Formula:C15H15F3N2OPurezza:98%Colore e forma:SolidPeso molecolare:296.29AR antagonist 5
CAS:<p>Compound 30a, known as AR Antagonist 5, is a selective androgen receptor (AR) antagonist that demonstrates an IC 50 value of 134.8 nM. It exhibits favorable pharmacokinetic properties, characterized by high skin exposure and low plasma exposure [1].</p>Formula:C23H21F3N6O2Colore e forma:SolidPeso molecolare:470.45(R)-Bicalutamide
CAS:(R)-Bicalutamide, an AR antagonist with antitumor properties, is crucial in prostate cancer research.Formula:C18H14F4N2O4SColore e forma:SolidPeso molecolare:430.37AR antagonist 2
CAS:AR antagonist 2 (compound 58) is a potent inhibitor of the androgen receptor (AR) (IC50: 0.95 μM).Formula:C22H17ClFN5O2SColore e forma:SolidPeso molecolare:469.92Bromopropylate
CAS:Bromopropylate is an insecticide. Bromopropylate is the active substance in fumigant strips for mites.Formula:C17H16Br2O3Purezza:98%Colore e forma:White Crystalline Solid Yellowish CrystalsPeso molecolare:428.11S-40503
CAS:S-40503 is an investigational selective androgen receptor modulator (SARM).Formula:C15H23N3O3Colore e forma:SolidPeso molecolare:293.36Ralaniten
CAS:Ralaniten (EPI-002), a potent AR-NTD antagonist, inhibits AR with IC50 of 7.4 μM, for CRPC study.Formula:C21H27ClO5Purezza:99.96%Colore e forma:SolidPeso molecolare:394.89Ref: TM-T28502
1mg40,00€5mg88,00€10mg126,00€25mg250,00€50mg393,00€100mg628,00€200mg879,00€1mL*10mM (DMSO)87,00€Androgen receptor antagonist 1
CAS:Androgen receptor antagonist 1, an oral full AR antagonist (IC50 59 nM), for PROTAC synthesis, reducing AR protein by 24–47% in LNCaP cells at 1–10 μM.Formula:C21H25ClN4O3Purezza:99.054%Colore e forma:SolidPeso molecolare:416.9RU 58642
CAS:RU 58642 is an effective systemic antiandrogen for androgen-dependent disorders.Formula:C15H11F3N4O2Purezza:98%Colore e forma:SolidPeso molecolare:336.27Cyprodinil
CAS:Cyprodinil is a fungicide blocking methionine synthesis in fungi and hinders B. cinerea, P. herpotrichoides, H. oryzae growth; it's also an AR agonist.Formula:C14H15N3Colore e forma:SolidPeso molecolare:225.29VPC-14449
CAS:VPC-14449 is a selective androgen receptor DNA-binding domain (AR-DBD) inhibitor, useful in prostate cancer research.Formula:C10H10Br2N4OSPurezza:99.56%Colore e forma:SolidPeso molecolare:394.09BMS-564929
CAS:BMS-564929 is an AR agonist that upregulates the expression and activity of fat-producing enzymes, reducing VAT content and lipid levels.Formula:C14H12ClN3O3Purezza:98.17%Colore e forma:SolidPeso molecolare:305.72VPC-13789
CAS:VPC-13789: potent, selective oral antiandrogen for CRPC with 0.19 μM IC50 in LNCaP cells.Formula:C21H16F3N3OColore e forma:SolidPeso molecolare:383.37Androgen receptor antagonist 3
CAS:Androgen receptor antagonist 3 (Compound C18) has anticancer activities that is an antagonist of androgen receptor (AR) (IC 50 = 2.4 μM) [1].Formula:C22H18ClNColore e forma:SolidPeso molecolare:331.84(R)-UT-155
CAS:(R)-UT-155 is a selective androgen receptor degrader (SARD) ligand.Formula:C20H15F4N3O2Colore e forma:SolidPeso molecolare:405.35Lubabegron fumarate
CAS:Lubabegron (LY591281, LY488756 fumarate) is a beta-agonist approved in 2018 to lower ammonia in cattle waste, aiding environment and health.Formula:C29H29N3O3SC4H4O4Colore e forma:SolidPeso molecolare:557.66MK-4541
CAS:MK-4541: oral, selective AR modulator, blocks 5α-reductase, curbs AR+ prostate cancer growth, effective in mouse model.Formula:C22H31F3N2O3Colore e forma:SolidPeso molecolare:428.49HG122
CAS:HG122 promotes AR degradation via proteasome, inhibiting castration-resistant prostate cancer.Formula:C15H13N5O5Colore e forma:SolidPeso molecolare:343.29LGD-2226
CAS:LGD-2226: selective oral androgen receptor modulator, EC50: 0.2nM, Ki: 1.5nM. Treats muscle loss, osteoporosis, sexual issues.Formula:C14H9F9N2OPurezza:98%Colore e forma:SolidPeso molecolare:392.22Dimethomorph
CAS:Dimethomorph is a fungicide and sterol biosynthesis inhibitor that inhibits fungal cell wall formation,. inhibits androgen receptor (AR) .Formula:C21H22ClNO4Purezza:99.20%Colore e forma:Solid CrystallinePeso molecolare:387.86CSRM617
CAS:CSRM617: selective ONECUT2 inhibitor, Kd 7.43 uM, binds OC2-HOX, induces apoptosis, tolerable in mouse prostate cancer model.Formula:C10H13N3O5Purezza:98%Colore e forma:SolidPeso molecolare:255.23MK-3984
CAS:MK-3984 is a selective androgen receptor modulator, used in the study of conditions caused by androgen deficiency.Formula:C17H12F7NO2Purezza:99.91%Colore e forma:SolidPeso molecolare:395.27TFM-4AS-1
CAS:androgen receptor modulatorFormula:C27H33F3N2O2Purezza:98%Colore e forma:SolidPeso molecolare:474.56VPC-3033
CAS:VPC-3033 is an antagonist of the androgen receptor. It acts by inhibiting the LNCaP cell line as well as cell lines with the wild-type androgen receptor.Formula:C21H14O2Purezza:98%Colore e forma:SolidPeso molecolare:298.33Topterone
CAS:Topterone (Win 17,665) is a potent topical antiandrogen that inhibits the stimulation of lumbar organ development by testosterone and dihydrotestosterone inFormula:C22H34O2Purezza:>99.99%Colore e forma:SolidPeso molecolare:330.5Ar-V7-IN-1
CAS:Ar-V7-IN-1 (compound 47) is a potent inhibitor of Ar-V7,associated with resistance to AR-targeted therapy with desmoplasia-resistant prostate cancer (mCRPC).Formula:C10H10Br2N4OSColore e forma:SolidPeso molecolare:394.09Carbazole derivative 1
CAS:Carbazole derivative 1 is used to reduce androgen or oestrogen levels in mammals.Formula:C18H13FN2Purezza:98%Colore e forma:SolidPeso molecolare:276.31Seviteronel
CAS:Seviteronel (VT-464) is a novel CYP17 cleavage enzyme inhibitor and androgen receptor antagonist for the study of breast and prostate cancer.Formula:C18H17F4N3O3Purezza:99.67% - 99.98%Colore e forma:SolidPeso molecolare:399.34BMS-641988
CAS:BMS-641988 is a novel nonsteroidal androgen receptor antagonist for the treatment of prostate cancer.Formula:C20H20F3N3O5SPurezza:99.3% - 99.92%Colore e forma:SoildPeso molecolare:471.45Rosolutamide
CAS:Rosolutamide (ALZ-003) is a curcumin analog, an Nrf1 and Nrf2 activator.Formula:C28H32O6Purezza:95.48% - 99.15%Colore e forma:SolidPeso molecolare:464.55Ralaniten triacetate
CAS:Ralaniten triacetate (EPI-506) is a precursor of Ralaniten, an AR-NTD inhibitor, which can be used in the study of prostate and breast cancer.Formula:C27H33ClO8Purezza:98.69%Colore e forma:SolidPeso molecolare:521.00Ref: TM-T36375
1mg162,00€5mg393,00€10mg655,00€25mg1.415,00€50mg1.882,00€100mg2.375,00€1mL*10mM (DMSO)449,00€ONC1-13B
CAS:ONC1-13B, an androgen receptor antagonist, is used potentially for the treatment of prostate cancer.Formula:C22H16F4N4O3SPurezza:99.36% - 99.85%Colore e forma:SolidPeso molecolare:492.45GLPG0492
CAS:GLPG0492 is a novel selective androgen receptor modulator.Formula:C19H14F3N3O3Purezza:99.58%Colore e forma:SolidPeso molecolare:389.33Ref: TM-T11410L
1mg74,00€5mg164,00€10mg235,00€25mg378,00€50mg543,00€100mg730,00€200mg938,00€1mL*10mM (DMSO)170,00€Androgen receptor antagonist 5
CAS:AR antagonist 5 blocks AR (IC50: 6.17 μM), hinders LNCaP cell growth, and has anti-tumor effects in mouse models.Formula:C21H15F4N5O3SColore e forma:SolidPeso molecolare:493.43Celiprolol hydrochloride
CAS:Celiprolol hydrochloride (Selectrol) is a cardioselective beta-1 adrenergic antagonist that has intrinsic sympathomimetic activity.Formula:C20H33N3O4·HClColore e forma:White Crystalline SolidPeso molecolare:415.96VPC-14228
CAS:VPC-14228 is a specific AR-DBD inhibitor that acts by inhibiting both Y594A and Q592A mutants.Formula:C13H14N2OSPurezza:99.96%Colore e forma:SolidPeso molecolare:246.33N-Nitrosodicyclohexylamine
CAS:N-Nitrosodicyclohexylamine (NDCHA), an N-nitrosocompound, exhibits anti-androgenic activity by competitively binding to the androgen receptor (AR) in oppositionFormula:C12H22N2OPurezza:98%Colore e forma:SolidPeso molecolare:210.32Androgen receptor degrader-2
CAS:Androgen Receptor Degrader-2 (Compound 9) is a potent degrader of androgen receptors, with potential application in cancer research [1].Formula:C16H16ClN3O4Purezza:98%Colore e forma:SolidPeso molecolare:349.77(rel)-BMS-641988
CAS:(rel)-BMS-641988, a relative configuration of the potent nonsteroidal androgen receptor antagonist BMS-641988, holds potential for prostate cancer research.Formula:C20H20F3N3O5SPurezza:98%Colore e forma:SolidPeso molecolare:471.45JNJ-26146900
CAS:JNJ-26146900 is a nonsteroidal androgen receptor (AR) ligand with tissue-selective activity in rats. JNJ-26146900 binds to the rat AR with a K(i) of 400nM.Formula:C15H15F3N2O3SPurezza:98%Colore e forma:SolidPeso molecolare:360.35Trimegestone
CAS:Trimegestone, a highly effective oral progestogen, is used for endometrial protection, all doses inducing secretory endometrial transformation.Formula:C22H30O3Purezza:98%Colore e forma:SolidPeso molecolare:342.47YXG-158
CAS:YXG-158 (Compound 23-h), an orally active androgen receptor (AR) degrader and cytochrome P450 17A1 (CYP17A1) inhibitor, exhibits AR degradation with a DC50 of 1Formula:C30H36FN3OPurezza:98%Colore e forma:SolidPeso molecolare:473.62Androgen receptor degrader-3
CAS:Androgen Receptor Degrader-3 (ARD-3) is a compound that inhibits androgen receptor signaling and promotes the degradation of the receptor, with potentialFormula:C45H51ClN8O5Purezza:98%Colore e forma:SolidPeso molecolare:819.39PLK1/BRD4-IN-1
CAS:PLK1/BRD4-IN-1 (9b) is an orally active dual inhibitor of PLK1 (IC50: 22 nM) and BRD4 (IC50: 109 nM).Formula:C31H43N9O2Colore e forma:SolidPeso molecolare:573.73Androgen receptor-IN-5
CAS:Androgen receptor-IN-5 is a potent inhibitor of the androgen receptor with anticancer properties.Formula:C22H10Cl2F4N4OSPurezza:98%Colore e forma:SolidPeso molecolare:525.31Androgen receptor degrader-1
CAS:Androgen Receptor Degrader-1 (Compound 18) is a potent agent for androgen receptor degradation, applicable in cancer research [1].Formula:C15H14ClN3O4Purezza:98%Colore e forma:SolidPeso molecolare:335.74JJH260
CAS:JJH260, a N-hydroxy hydantoin carbamate, inhibits AIG1 and ADTRP with IC50 values of 0.57 μM and 8.5 μM, respectively, and targets ABHD6, LYPLA1/2.Formula:C29H34ClN5O5Colore e forma:SolidPeso molecolare:568.06EPI-7170
CAS:EPI-7170: Ralaniten analogue, blocks androgen receptor, inhibits transcription in AR & variants, fights enzalutamide-resistant prostate cancer.Formula:C22H28Cl3NO6SColore e forma:SolidPeso molecolare:540.88LGD-2941
CAS:LGD-2941 is an androgen receptor modulator. LGD-2941 is used for the treatment of hypogonadism, female sexual dysfunction and menopausal syndrome.Formula:C17H16F6N2O2Colore e forma:SolidPeso molecolare:394.31RU 59063
CAS:RU 59063 is a prototype of a new class of high-affinity nonsteroidal androgen receptor (AR) ligands.Formula:C17H18F3N3O2SPurezza:99.09%Colore e forma:SolidPeso molecolare:385.4Ref: TM-T20761
1mg87,00€5mg192,00€10mg284,00€25mg452,00€50mg645,00€100mg867,00€200mg1.130,00€1mL*10mM (DMSO)208,00€
