NF-κB
Il fattore nucleare kappa-light-chain-enhancer delle cellule B attivate (NF-κB) è un fattore di trascrizione che regola l'espressione di geni coinvolti nelle risposte immunitarie, nell'infiammazione, nella sopravvivenza cellulare e nella proliferazione. NF-κB viene attivato in risposta a vari stimoli, tra cui citochine, agenti patogeni e segnali di stress. La disregolazione della segnalazione di NF-κB è associata a malattie infiammatorie croniche, cancro e disturbi autoimmuni. Presso CymitQuimica, offriamo una selezione completa di modulatori della via NF-κB per supportare la tua ricerca su infiammazione, oncologia e regolazione immunitaria.
Trovati 443 prodotti di "NF-κB"
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Cyclo(his-pro)
CAS:<p>Cyclo(his-pro) is a cyclic dipeptide that shields against oxidative damage by activating Nrf2.</p>Formula:C11H14N4O2Purezza:99.87%Colore e forma:SolidPeso molecolare:234.25MD2-TLR4-IN-1
CAS:<p>MD2-TLR4-IN-1 is a myeloid differentiation protein 2/toll-like receptor 4 (MD2-TLR4) complex inhibitor.</p>Formula:C22H14Cl2N4OPurezza:97.74%Colore e forma:SolidPeso molecolare:421.28ETHYL CAFFEATE
CAS:<p>Ethyl Caffeate (ETHYL 3,4-DIHYDROXYCINNAMATE) suppressed the differentiation of naive CD4+ T cells into Th1 in vitro.</p>Formula:C11H12O4Purezza:97.79%Colore e forma:SolidPeso molecolare:208.21Denosumab
CAS:<p>Denosumab is a monoclonal antibody given subcutaneously that inhibits osteoclast activity by targeting the RANK ligand</p>Formula:C6404H9912N1724O2004S50Purezza:95.9% (SDS-PAGE); 98.4% (SEC-HPLC) - 99.90%Colore e forma:LiquidPeso molecolare:144.71 kDaGSK8612
CAS:<p>GSK8612 is a highly selective and potent inhibitor of Tank-binding Kinase-1 (TBK1, pIC50: 6.8) .</p>Formula:C17H17BrF3N7O2SPurezza:99.46% - 99.8%Colore e forma:SolidPeso molecolare:520.33Tizoxanide
CAS:Tizoxanide (Desacetyl-nitazoxanide) is a metabolite of lamivudine.Formula:C10H7N3O4SPurezza:98.89% - 99.28%Colore e forma:SolidPeso molecolare:265.25Avicularin
CAS:<p>Avicularin reduces inflammation via ERK pathway in RAW 264.7 cells and hinders lipid buildup in adipocytes by limiting glucose uptake and fatty acid synthesis.</p>Formula:C20H18O11Purezza:97.02% - 99.94%Colore e forma:White PowderPeso molecolare:434.35Ginsenoside Rb3
CAS:<p>Ginsenoside Rb3 (Gypenoside IV) is a natural triterpenoid saponin, exhibiting inhibition effect on TNFα-induced NF-κB transcriptional activity.</p>Formula:C53H90O22Purezza:98% - 99.98%Colore e forma:SolidPeso molecolare:1079.27MLN120B
CAS:<p>MLN120B is a selective and ATP competitive IKKβ inhibitor (IC50: 60 nM).</p>Formula:C19H15ClN4O2Purezza:98.92%Colore e forma:SolidPeso molecolare:366.8Eclitasertib
CAS:<p>Eclitasertib is a potent inhibitor of receptor-interacting protein kinase 1 (RIPK1, IC50 of <1 µΜ).</p>Formula:C19H18N6O3Purezza:99.85%Colore e forma:SolidPeso molecolare:378.38Berbamine
CAS:<p>Berbamine is a natural product extracted from Phellodendron amurense.</p>Formula:C37H40N2O6Purezza:98.92% - 99.67%Colore e forma:White Crystal PowderPeso molecolare:608.72Isoquercetin
CAS:<p>1.</p>Formula:C21H20O12Purezza:98.08% - 99.76%Colore e forma:SolidPeso molecolare:464.38WITHAFERIN A
CAS:<p>WITHAFERIN A is a novel class of NFkappaB inhibitors, which hold promise as novel anti-inflammatory agents for treatment of various inflammatory disorders and/</p>Formula:C28H38O6Purezza:97.41% - 99.99%Colore e forma:SolidPeso molecolare:470.6Ginsenoside Rd
CAS:<p>Ginsenoside Rd (Gypenoside VIII) may have properties that inhibit or prevent the growth of tumors.</p>Formula:C48H82O18Purezza:99.13% - 99.92%Colore e forma:SolidPeso molecolare:947.15Dehydroevodiamine
CAS:<p>Dehydroevodiamine (DHED), a constituent of Evodia rutaecarpa, has various biological effects such as hypotensive, negative chronotropic, ion channel depressant</p>Formula:C19H15N3OPurezza:99.54%Colore e forma:SolidPeso molecolare:301.34IRAK inhibitor 6
CAS:<p>IRAK inhibitor 6 is an inhibitor of interleukin-1 receptor-associated kinase 4 (IRAK-4, IC50: 160 nM).</p>Formula:C20H20N4O3SPurezza:99.44%Colore e forma:SolidPeso molecolare:396.462-Hydroxychalcone
CAS:<p>2-Hydroxychalcone (2-(2-Hydroxybenzal)Acetophenone) can be used as antiparasitic hit compounds when Methoxylated. It inhibits invasion of breast cancer cells.</p>Formula:C15H12O2Purezza:99.6%Colore e forma:SolidPeso molecolare:224.252,5-Dihydroxyacetophenone
CAS:<p>2,5-Dihydroxyacetophenone has anti-anxiety, neuroprotective, anti-inflammatory properties, and modulates cell signaling and melanogenesis.</p>Formula:C8H8O3Purezza:99.75%Colore e forma:Yellow PowderPeso molecolare:152.15Muscone
CAS:<p>Muscone (3-Methylcyclopentadecanone) is an organic compound that is the primary contributor to the odor of musk.</p>Formula:C16H30OPurezza:98.97% - ≥98%Colore e forma:Colourless Liquid LiquidPeso molecolare:238.41Phellodendrine
CAS:<p>Phellodendrine may treat nephritis by blocking macrophage and T cell activity in glomeruli.</p>Formula:C20H24NO4Purezza:98.7% - 99.94%Colore e forma:SolidPeso molecolare:342.41
